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1 hesis of NAD (+) and clearing the neurotoxin quinolinate.
2 he phthalate catabolic pathway cometabolizes quinolinate.
3                                              Quinolinate achieved an AUC of 0.77 after 1 month of tre
4                      This pathway results in quinolinate, an excitotoxin that is an NMDA receptor ago
5 e enzymatic product subsequently cyclizes to quinolinate, an intermediate in the biosynthesis of nico
6                                 In contrast, quinolinate, an NMDA receptor agonist, produced only min
7 elis complex is approximated by PRPP and the quinolinate analogue phthalate bound to the active site.
8  formation of nicotinate mononucleotide from quinolinate and 5-phosphoribosyl-1-pyrophosphate (PRPP).
9 o and singly bound forms with the substrates quinolinate and PRPP.
10 ntrastriatal injection of either malonate or quinolinate and systemic administration of 3-NP resulted
11 e "activity" reported does not correspond to quinolinate formation.
12                                              Quinolinate has also been implicated in important neurol
13                               High levels of quinolinate have been correlated with the etiology of ne
14                                              Quinolinate-induced stimulation of intracellular NAD in
15 h necrotic morphologies were detected in the quinolinate-injected striata.
16 cted outside the needle track 10 hours after quinolinate injection and, on average, 20% of neurons ex
17 ced hippocampal cell death, are resistant to quinolinate, malonate, and 3-nitropropionic acid (3-NP).
18 Rats were killed 6, 8, 10, or 12 hours after quinolinate or vehicle injection.
19 of two metabolic pathways: the tryptophan to quinolinate pathway and the bacterial 2-nitrobenzoic aci
20  NCQDs were immobilized with an enzyme named quinolinate phoshphoribosyl transferase (QPRTase).
21                                Low placental quinolinate phosphoribosyl transferase (QPRT), the enzym
22             The fact that elevated levels of quinolinate phosphoribosyl transferase enhance growth on
23                 A gene coding for an enzyme (quinolinate phosphoribosyl transferase) involved in the
24 e biosynthetic pathway including NtPMT1a and quinolinate phosphoribosyltransferase (NtQPT2), and lowe
25                                              Quinolinate phosphoribosyltransferase (QAPRTase, EC 2.4.
26                                              Quinolinate phosphoribosyltransferase (QAPRTase, EC 2.4.
27 tion of a bottleneck enzyme in this pathway, quinolinate phosphoribosyltransferase (QPRT) may contrib
28 ave one de novo pathway gene, nadC, encoding quinolinate phosphoribosyltransferase.
29 tructural similarities between phthalate and quinolinate: phthalate is a competitive inhibitor of thi
30     When supplied as the sole NAD precursor, quinolinate promoted B. bronchiseptica growth, and the a
31 metabolism of tryptophan and accumulation of quinolinate (QA) as a metabolic node in glioblastoma and
32                                  Indeed, the quinolinate (Qa) phosphoribosyltransferase activity of N
33                                              Quinolinate (Quin), a metabolite in the kynurenine pathw
34                                              Quinolinate synthase (NadA) catalyzes a unique condensat
35                                              Quinolinate synthase (NadA) catalyzes a unique condensat
36                                              Quinolinate synthase (NadA) is a Fe4S4 cluster-containin
37 AP) and iminoaspartate (IA) by the action of quinolinate synthase (NadA).
38 DHAP) and aspartate-enamine by the action of quinolinate synthase (NadA).
39 entified by MutMap in the encoding region of Quinolinate Synthase (QS) gene required for the de novo
40 S cysteine desulfurase activity 70-fold) and quinolinate synthase activity.
41 chosen the [4Fe-4S] cluster-dependent enzyme quinolinate synthase to illustrate each one of these pro
42 ike and one with similarity to the bacterial quinolinate synthase, NadA.
43 study concludes that all currently annotated quinolinate synthases harbor a [4Fe-4S] cluster, that th
44  the biosynthetic pathway from tryptophan to quinolinate, the universal de novo precursor to the pyri
45 sis by limiting the conversion of downstream quinolinate to NAD(+), a profile recapitulated in aging
46  ratios of 3-sialyllactose to xanthosine and quinolinate to X-16397 and our previously reported urina
47 e, fumarate, hypoxanthine, acetone, leucine, quinolinate, valine, O-acetylcarnitine, citrate, and tri
48                                              Quinolinate was also significantly associated with prese
49 metabolites (kynunerate, 8-methoxykyunerate, quinolinate) were higher in patients who developed AKI.