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1 mparable) sugar acids and sugar alcohols are racemic.
2 s viable and that natural paracaseolide A is racemic.
3 d to radical reactions, which are invariably racemic.
9 emporary substitution of chloride ligands by racemic 4-(s) Bu-phenolates and subsequent crystallizati
10 iox = 9, 10-dihydroxyphenanthrene, rac-cth = racemic 5, 5, 7, 12, 12, 14-hexamethyl-1, 4, 8, 11-tetra
11 to the enhanced fibril formation propensity, racemic Abeta42 was less prone to form soluble oligomers
13 RhCl(CS-L)]2 were employed in 1,2-additions, racemic addition products were observed, suggesting a C
17 ctivity and mechanism of action of RJW100, a racemic agonist of the nuclear receptors liver receptor
18 , as well as chiral amines directly from the racemic alcohol precursors in up to >97 % ee, releasing
21 (coined coetaneous) kinetic resolution of a racemic alkyne and racemic azide, utilising an asymmetri
22 of Rh(I) catalysts enables the conversion of racemic allene to enantiopure cyclopentenone product in
28 dditions of alkylzirconocene nucleophiles to racemic allylic halide electrophiles were conducted usin
30 ing group and ligand to enable conversion of racemic allylic trichloroacetimidates to the correspondi
31 ve formation of substituted spiroketals from racemic, allylic carbonates is reported, which enables t
33 has been developed for the transformation of racemic alpha-bromo ketones to chiral alpha-azido and al
34 ism of enantioconvergent Kumada reactions of racemic alpha-bromoketones catalyzed by a nickel complex
35 unprecedented stereodivergent resolution of racemic alpha-chiral carboxylic acids, thus providing ac
36 t alkyl-alkyl couplings of readily available racemic alpha-haloboronates with organozinc reagents und
37 catalyst can accomplish Negishi reactions of racemic alpha-halosilanes with alkylzinc reagents with g
38 Here, the enantioselective conversion of racemic alpha-tosyloxy ketones to optically enriched alp
40 ch, the classical kinetic resolutions of the racemic amines have been investigated using Candida anta
43 tegy allowed the efficient synthesis of both racemic and (S)-configured puraquinonic acid, deliquinon
45 re synthesized from a common intermediate in racemic and enantioenriched forms using Pd(0)-catalyzed
47 behavior of real chiral molecules, including racemic and enantiopure crystals, as well as amorphous s
48 s of lundurines A-C has been accomplished in racemic and enantiopure forms in 11-13 and 12-14 steps,
49 erimental and theoretical comparison between racemic and enantiopure samples revealed that the two en
50 phenyl packing motifs between some groups of racemic and enantiopure structures, although they show v
56 nces observed in the (1)H NMR spectra of the racemic and the enantio-enriched compounds in an achiral
58 fluoro-alpha,beta-unsaturated esters both in racemic and, for the first time, in enantioselective ver
59 iPPO including enantiopure, enantioenriched, racemic, and stereoblock were synthesized with a single
62 ) kinetic resolution of a racemic alkyne and racemic azide, utilising an asymmetric CuAAC reaction is
67 ent arylation reactions of boronic acids and racemic beta-stereogenic alpha-keto esters have been dev
69 dynamic kinetic asymmetric transformation of racemic biaryl substrates on the basis of axial-to-centr
70 mmonium salt catalyzed kinetic resolution of racemic BINOLs with benzyl tosylate proceeds with s up t
71 ntioselective Tsuji-Trost-type aminations of racemic branched alkyl-substituted allylic acetates usin
72 r-catalyzed enantioselective fluorination of racemic, branched allylic trichloroacetimidates with Et3
74 ts 2,3-dihydro isomer 2, which is chiral and racemic, by base-catalyzed olefin isomerization followed
78 e sensors for enantiodiscrimination of alpha-racemic carboxylic acids containing tertiary or quaterna
80 onstrate that illumination of dispersions of racemic CdTe NPs with right- (left-)handed circularly po
81 oted by amidine-based catalysts (ABCs) and a racemic chain mechanism mediated by a thiolate nucleophi
83 lysis shows that host-guest interactions and racemic cocrystallization allow for controlling the soli
84 he nematic elasticity to predefine chiral or racemic colloidal superstructures in nematic colloids.
86 rom resolution) in complex with fadrozole, a racemic compound normally used to treat breast cancer by
87 tereoselective interaction of a benzothiazol racemic compound that acts as a positive allosteric modu
88 perform both the kinetic resolution (KR) of racemic compounds and the desymmetrization of centrosymm
90 improve on the therapeutic promise of other racemic compounds, including the development of safer th
94 eric assembly is precisely reproduced in the racemic crystal, which strengthens the conclusion that t
95 ructural analysis providing insight into the racemic crystallization process as well as structural de
96 vincing evidence of the applicability of the racemic crystallization technique to DNA through the stu
97 rystals containing ferric enterobactin using racemic crystallization, a method that involves cocrysta
99 More broadly, these findings suggest that racemic crystallography can provide insight on native qu
100 ork highlights the utility of small-molecule racemic crystallography for obtaining elusive structures
103 termined the X-ray structure of ShK toxin by racemic crystallography, in the course of which we disco
105 d strategy enables the kinetic resolution of racemic cyclic 2-arylamines, using benzyl acrylate as th
107 selective ring-opening (co)polymerization of racemic cyclic diolides (rac-8DL(R) , R=alkyl group).
108 es were not suitable for resolution of these racemic cyclic nitrogenated amines, alternative chemoenz
116 report a chiral nickel catalyst that couples racemic electrophiles (propargylic halides) with racemic
117 specifically, enantioconvergent couplings of racemic electrophiles-that substantially enhances the al
118 inely arranged triangular necklace 1 has two racemic enantiomers in its solid state with intriguing p
119 layer composed of enantiomorphic domains of racemic entities is demonstrated by scanning tunneling m
120 ations, we developed a kinetic resolution of racemic epoxides, which proceeds with high selectivity (
121 sed, beta-lactones were first synthesized in racemic fashion via the NCAL process with excellent dias
124 This represents the first example to use a racemic fluorescent probe to determine the ee of a chira
125 dendrimer, contains a combination of chiral-racemic fluorinated and achiral hydrogenated dendrons (R
126 Two Janus dendrimers contain either chiral-racemic fluorinated dendrons and a green fluorescent dye
127 ules contain environmentally friendly chiral-racemic fluorinated dendrons in their hydrophobic part (
128 e absence of a ligand, the reaction provided racemic Fmoc-protected amino alcohols with excellent reg
129 l alkaloid and biosynthetic intermediates in racemic form and in vitro enzymatic reconstitution to pr
130 id 7-hydroxydocosahexaenoic acid (7-HDHA) in racemic form and the enantioselective synthesis of 7-(S)
133 carbons, has been achieved in seven steps in racemic format from tryptamine and in nine steps in asym
136 re attractive to beetles of both sexes, than racemic fuscumol and a blend of host plant volatiles com
137 ective Suzuki-Miyaura cross-coupling between racemic fused bicyclic allylic chlorides and boronic aci
145 tuted cyclopentanones, which can be prepared racemic (in six steps) or optically pure (in ten steps)
146 oute involved the late-stage resolution of a racemic intermediate to provide both enantiomers of this
147 ved in the alkynylation of widely available, racemic isochroman and chromene acetals to deliver alpha
148 lins, and we enantioselectively crystallized racemic jasmonic acid, whose absolute configuration had
149 s efficient conversion of readily available, racemic ketals into high-value enantioenriched isochroma
150 tion, acid-catalyzed cyclization to form the racemic ligand alcohol, and an enzymatic resolution with
158 a stereoconvergent oxidative dimerization of racemic materials in a transformation that likely coinci
161 ed employing a stereodivergent reaction of a racemic mixture (stereodivergent RRM) involving [4+2] cy
162 By enantioselective HPLC, we solved the racemic mixture and ascertained that the two enantiomers
163 applied for the estimation of ETB isomers in racemic mixture and real samples viz., blood, urine and
164 esis of molecular structures from an initial racemic mixture and without the need of enantiopure modi
165 tallization of chiral small molecules from a racemic mixture but also imposes diastereoselective inco
166 recognition of an enantiomeric guest from a racemic mixture by a chiral host is well-known, present
169 racemization is a powerful method by which a racemic mixture can be transformed into an excess of one
170 tereoselective metabolism within the body, a racemic mixture in wastewater suggests a nonconsumed dru
171 dsorption of one enantiomer from the aqueous racemic mixture into the chiral pores of the AAO membran
172 Dosing with (+)-pioglitazone instead of the racemic mixture may result in higher levels of brain exp
175 t of sergeants (0.5%) or a small bias from a racemic mixture of enantiopure comonomers (10% ee).
176 prepared on a solid phase using l-Ser and a racemic mixture of Fmoc- trans-2-aminocyclohexanecarboxy
178 d either an intravenous saline infusion or a racemic mixture of ketamine (100 ng/ml) separated by at
179 (+)- and S-(-)-enantiomers and the R,S-(+/-) racemic mixture of LA or lipoamide, we identified the bi
181 rated in vivo by E. coli is expected to be a racemic mixture of the (R) and (S) enantiomers, so it ha
183 line systems showed that each conjugate is a racemic mixture of two atropisomers resulting from the a
187 ogical activities of the two enantiomers and racemic mixture were tested in a New Zealand vineyard.
188 the high load of fluoxetine was present as a racemic mixture, which is typical for fluoxetine in disp
194 wing question based on available data: in 2D racemic mixtures adsorbed on surfaces, is there a clear
197 e of 1S and 1R with respect to resolution of racemic mixtures of 1-phenyl-1-propanol (PP) was studied
199 uid crystals (NLCs) of achiral molecules and racemic mixtures of chiral ones form flat films and show
203 It has previously been shown that the use of racemic mixtures of naturally chiral macromolecules such
204 Stereodynamic probes typically consist of racemic mixtures of rapidly interconverting enantiomeric
205 ttribute specific activities are produced as racemic mixtures of stereoisomers, and it may be that al
207 ipids, but these studies were performed with racemic mixtures, and the role of stereochemistry remain
208 wn to be able to separate a variety of model racemic mixtures, including drugs, in a wide range of so
210 umed that chemical reactions produced 50:50 (racemic) mixtures of enantiomers, as evidenced by common
211 ing a cationic cyclization process, into the racemic modification of the unusual uleine alkaloid gilb
213 and this could be readily elaborated to the racemic modifications of the alkaloids uleine, dasycarpi
215 n, the stereoselective polymerization of the racemic monomer by yttrium catalysts bearing tetradentat
216 transition from homochiral nuclei to larger racemic motifs, although the extended homochiral phase e
219 e one-step bicyclization of 10-oxocitral to (racemic) nepetalactone in diastereomerically pure form.
221 mic electrophiles (propargylic halides) with racemic nucleophiles (beta-zincated amides) to form carb
222 these reactions use a single enantiomer from racemic nucleophiles to afford stereopure quaternary car
223 he term flavonolignin is recommended for the racemic oligomers and polymers of monolignols that start
226 ngenic wild type (WT) mice were treated with racemic PCB 136, and levels and chiral signatures of PCB
228 unexpected outcome from crystallization of a racemic peptide corresponding to the transmembrane domai
229 ranging from aggregates made of natural and racemic peptides and DNA, through artificial functional
232 In a Leishmania donovani mouse model, two racemic phenylpyridines (71 and 93) were superior, with
233 chiral amines and easily prepared achiral or racemic phosphoric acids, together with a suitable Pd-so
236 Such a large nonlinear effect allows the racemic polymer rac-1 to be used to determine the ee of
237 A straightforward approach using a common racemic precursor was employed to obtain the desired opt
238 lly reported to lack activity when used as a racemic preparation, is an alpha7 nicotinic acetylcholin
242 f the nonaxially chiral derivatives from the racemic products were found to be optically stable under
246 These atactic polymers are produced from racemic propylene oxide using chain shuttling agents and
247 telechelic isotactic PPO is synthesized from racemic propylene oxide with control of molecular weight
248 of the Ts3 protein molecule, and the use of racemic protein crystallography to determine the folded
249 (i) enantioselective transesterification of racemic proxyphylline with vinyl acetate as well as (ii)
253 cross-coupling, specifically, reactions of a racemic pyrrolidine-derived nucleophile with cyclic alky
254 omers with varying starting ratios of chiral racemic (rac) and achiral meso diastereomers into stereo
255 ver exhibited the highest deviation from the racemic ratio, indicating enantiomer-selective metabolis
257 elopment of the methodology from the initial racemic report to recent asymmetric examples is summariz
260 gly, NMR and X-ray analysis gave exclusively racemic (RR/SS)-1,2-disilane 3a, indicating a stereospec
261 nctional theory calculations reveal that the racemic RS dimer is more stable than the RR dimer as a r
264 sts, well-known in asymmetric hydrogenation, racemic secondary alcohols are shown to couple with prim
265 Under the co-catalysis of a ketone and NaOH, racemic secondary alcohols reacted with Ellman's chiral
266 antioconvergent nucleophilic substitution of racemic secondary alkyl halides (alpha-iodolactams) by i
267 gs of arylzinc reagents with CF3-substituted racemic secondary alkyl halides, a process that necessit
268 ogen-borrowing process, the catalysis allows racemic secondary allylic alcohols to react with various
269 omplexes derived from 2-lithio furan and non-racemic secondary and tertiary alkyl or aryl boronic est
270 d with a new environmentally friendly chiral racemic semifluorinated alkyl group and with AB3 miniden
271 o allows highly enantioselective addition to racemic seven-membered-ring allyl chlorides for the firs
273 ess also provides direct access to novel non-racemic spirolactam scaffolds that are likely to be of i
274 China show smaller deviations from those of racemic/standard compound, indicating the DDT residues t
275 n enantioconvergent mechanism transforms the racemic starting material into a single product enantiom
276 se when there is a kinetic resolution of the racemic starting material, and its magnitude is correlat
278 cts a simultaneous kinetic resolution of two racemic starting materials to give one major triazolic d
279 hates undergo stereospecific reactions and a racemic substrate undergoes a Cu-catalyzed kinetic resol
280 bled the enantioconvergent transformation of racemic substrates that possess a tertiary C(sp(3))-H bo
281 configuration of the drug is responsible for racemic switch with enantiomers in presence of chiral en
282 describe here the diastereocontrolled formal racemic syntheses of tricyclic marine alkaloids, lepadif
283 ng enantiopure reference compounds of eleven racemic TAGs with C12-C22 fatty acids with 0-2 double bo
284 butyl 3,4-dihydroxybutanoate carbonate) from racemic-tert-butyl 3,4-epoxybutanoate (rac-(t)Bu 3,4-EB)
285 alyzed method for coupling readily available racemic tertiary alkyl chloride electrophiles with amine
286 alyze the enantioconvergent 1,6-amination of racemic tertiary C(sp(3))-H bonds at the optimal tempera
288 rise to deracemizative functionalization of racemic tertiary C-H bonds for stereoselective construct
291 , racemic trans-1,2-diaminocyclopentane, and racemic trans-1,2-diaminocyclohexane and theoretical cal
292 ompetition reaction of 2,6-diformylpyridine, racemic trans-1,2-diaminocyclopentane, and racemic trans
293 nitial hit 2, resulting in identification of racemic-trans-(3-((4-(aminomethyl)-6-(trifluoromethyl)py
298 st one of the polypeptides in the mixture is racemic, which disrupts backbone hydrogen-bonding networ
299 K analogue proteins were determined by quasi-racemic X-ray crystallography and were similar to wild-t
300 ed by Cu-catalyzed [3 + 2] cycloadditions of racemic (Z)-2-benzylidene-5-oxopyrazolidin-2-ium-1-ides