ライフサイエンスコーパス: racemize

1 st abundant abiotic amino acids, glycine and racemized alanine, dried and reconstituted MU soup was f

2 The identification of racemized amino acid residue(s) by mass spectrometry is

3 m mass spectrometry (CID-MS/MS) to elucidate racemized amino acid residues in immunoglobulin samples.

4 methodology successfully identified several racemized amino acid residues in the constant region of

5 mized peptides and elucidate the location of racemized amino acid residues.

6 iment that abiotically produced a mixture of racemized amino acids, we provide a definite proof that

7 They cannot racemize and have a small but real excess of those with

8 4 may be recovered from the resolution step, racemized, and resubjected to enzymatic acylation to inc

9 highly selective toward L-serine, failing to racemize any other amino acid tested.

10 be particularly elusive, and its ability to racemize as a peptide-bound residue (like asparagine and

11 ation reactions that generate isomerized and racemized aspartyl derivatives.

12 Met)-dependent methylation of isomerized and racemized aspartyl residues in age-damaged proteins as p

13 y recognizing and methylating isomerized and racemized aspartyl residues in aging proteins.

14 taneously degrade, generating isomerized and racemized aspartyl residues.

15 dies; however, SeAdoMet and TeAdoMet did not racemize at detectable rates.

16 nzymatically synthesized AdoMet was found to racemize at rates that were consistent with earlier stud

17 ved from allenes bearing beta-hydrogen atoms racemize at room temperature by reversible beta-hydride

18 al derivatives, however, gave thiohydantoins racemized at C-5 of the heterocyclic ring.

19 igurationally stable at room temperature and racemizes at 199 degrees C with a half-time of about 11

20 organic molecule with helical chirality that racemizes at room temperature.

21 site in a pocket that excludes DNA bases and racemized beta-anomer AP sites.

22 Metallacycles derived from diarylallenes racemize by reversible thermal bond homolysis at 95 degr

23 phenylalanine, each of these amino acids was racemized by P. putida KT2440 enzymes.

24 gonist at many mature forebrain synapses) is racemized by the neuronal enzyme serine racemase (SR) fr

25 The enantiomeric capsules can interconvert (racemize) by dissociation and recombination of their sub

26 ions that allow the nitrogen stereocentre to racemize, chiral ammonium cations can be produced in exc

27 y stable below -95 degrees C, and the latter racemized completely at -50 degrees C.

28 Extension to non-racemizing conditions provides a novel methodology for c

29 growth and dissolution under solution-phase racemizing conditions.

30 mammalian enzyme can recognize spontaneously racemized d-aspartyl residues for conversion to l-aspart

31 tiary (3 degrees )-benzylic position was not racemized during oxidation, and methyl indoprofen was pr

32 econdary optically enriched amines have been racemized efficiently, with residence times compatible w

33 r PIMT target site in H2B) was significantly racemized, exhibiting d/l ratios as high as 0.12, wherea

34 Several Asp residues are racemized in Abeta plaque, with residue 1 being predomin

35 5'-phosphate (PLP) cofactor, but is neither racemized nor efficiently hydrolyzed.

36 eracemizations, which rely on the ability to racemize or interconvert enantiomers, are a promising se

37 In human serum at 37 degrees C (-)-3 did not racemize over the course of the 30 h study.

38 e mother liquors are continuously separated, racemized over a fixed-bed catalyst, and recirculated to

39 ts, these isoxazolidine alkaloids arise from racemizing oxidative rearrangements of prominent isoquin

40 andem mass spectrometry (LC-MS/MS) to detect racemized peptides and elucidate the location of racemiz

41 fications, the identification of isobaric or racemized peptides is confounded by modern mass spectrom

42 dynamic kinetic resolution (DKR) of rapidly racemizing precursors exhibiting free bond rotation.

43 how that the resolved, crystalline materials racemize quickly when dissolved at 5 degrees C.

44 tudies reveal that, while the parent amide 5 racemizes rapidly, for the sterically more hindered amid

45 l 2 is less configurationally stable than 1, racemizing rapidly in CHCl3 (t1/2(rac) = 1.9 h, rt), and

46 These compounds, however, racemized readily through rapid acyl migration and lost

47 th as a reagent for detecting isomerized and racemized residues in damaged proteins and for possible

48 The corresponding alpha-nitro amides racemized significantly during chromatography, but this

49 es; for 2m, 5600 degrees), but the molecules racemize slowly at room temperature (DeltaG++rac = 24 kc

50 cemization via temperature fluctuations in a racemizing solution (thanks to the presence of the base

51 Azirine-2-carboxylate esters were shown to racemize spontaneously.

52 with a nonchiral copper(II) complex that can racemize the ligand.

53 late stage indoline oxidation which does not racemize the product.

54 nism where complex oligomeric catalysts both racemize the starting material and select one enantiomer

55 he single mutations were unable to invert or racemize the stereochemistry of hydride transfer even th

56 A primary amine racemizes the aldehyde substrate via enamine formation a

57 t the Pt-N bond of the phenanthridine ligand racemizes the complex, and the question arises as to whe

58 ugh heterochirality or by partially or fully racemizing the dendritic dipeptide destructively interfe

59 in both selecting different pathways and in racemizing the starting material via formation of an all

60 Since this enantiomer is continuously racemized, the major enantiomer is enriched in the photo

61 The two enantiomers interconvert (racemize) through an achiral intermediate involving a sl

62 however, the sulfonium ion can spontaneously racemize to the R form, producing (R,S)-AdoMet.

63 The chiral sulfonium spontaneously racemizes to form a mixture of S and R isomers of AdoMet

64 These results quantify the intermediacy of a racemized triplet biradical (3)16 on the major rearrange

65 r of the alpha-nitro ester products does not racemize under controlled workup conditions.

66 thetic sample of cleroindicin F was found to racemize under slightly basic conditions.

67 results reveal that phenanthriplatin rapidly racemizes under physiological conditions.

68 homochiral, heterochiral, and differentially racemized variants is reported.

69 ion of conformationally chiral enolates that racemize very slowly under the reaction conditions.

70 hicine analogue without the acetamido group, racemizes within minutes.