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1 coli, Thermus thermophilus, and Deinococcus radiodurans.
2 e crystal structure of RecF from Deinococcus radiodurans.
3 tion resistance on the bacterium Deinococcus radiodurans.
4 t DNA strand-annealing system of Deinococcus radiodurans.
5 re of a prokaryotic Ro ortholog, Rsr from D. radiodurans.
6 f the large ribosomal subunit of Deinococcus radiodurans.
7 e activity, which occurs in IR-irradiated D. radiodurans.
8 atory mechanism of aromatic catabolism in D. radiodurans.
9 e to the ionizing radiation resistance in D. radiodurans.
10 single-stranded DNA-binding protein from D. radiodurans.
11 he radiation-resistant bacterium Deinococcus radiodurans.
12 ly radiation resistant bacterium Deinococcus radiodurans.
13 oneidensis, Escherichia coli and Deinococcus radiodurans.
14 ting the extraordinary radioresistance of D. radiodurans.
15 ng radiation-resistant bacterium Deinococcus radiodurans.
16 ng radiation-resistant bacterium Deinococcus radiodurans.
17 xtremely radioresistant organism Deinococcus radiodurans.
18 ly 210 peaks in the pI range of 3-8.8 for D. radiodurans.
19 cerevisiae, Eschericia coli, and Deinococcus radiodurans.
20 tecting against ROS are more resistant in D. radiodurans.
21 of the bacteriophytochrome from Deinococcus radiodurans.
22 tein, encoded by ORF DR_1909, of Deinococcus radiodurans.
23 sible for the high radiation tolerance of D. radiodurans.
24 context of severe genomic degradation in D. radiodurans.
25 compared to a tryptic digest of Deinococcus radiodurans.
26 nit complexes of the eubacterium Deinococcus radiodurans.
27 bacteriophytochrome (BphP) from Deinococcus radiodurans.
28 ons approached that exhibited by Deinococcus radiodurans.
29 still preserved in many species including D. radiodurans.
30 e transcriptional regulation of growth in D. radiodurans.
31 2 bridging 5 S and 23 S rRNAs) and 30 in D. radiodurans 23 S rRNA (plus 1 bridging 5 S and 23 S rRNA
33 ure in situ Mn(II) speciation in Deinococcus radiodurans, a radiation-resistant bacteria capable of a
34 whole-genome restriction map of Deinococcus radiodurans, a radiation-resistant bacterium able to sur
37 he radiation-resistant bacterium Deinococcus radiodurans accumulates less carbonylation than sensitiv
39 mple, we use data on survival of Deinococcus radiodurans after high doses (thousands of Gy) of acute
41 er bacteria, such as E. coli and Deinococcus radiodurans, although the average mutation rate per muta
42 mutations in Escherichia coli to Deinococcus radiodurans, an extremeophile with an astonishingly high
43 t are unable to replicate autonomously in D. radiodurans and carry homologous sequences for replaceme
44 e purified the RecN protein from Deinococcus radiodurans and characterized its DNA-dependent and DNA-
45 tails of the in vivo Mn(2+) speciation in D. radiodurans and E. coli cells and their responses to 10
48 40 of the large subunit rRNA in Deinococcus radiodurans and Escherichia coli, respectively, are phyl
49 ynthetase from M. jannaschii and Deinococcus radiodurans and its characterization in vitro and in viv
53 radiation-resistant eubacterium Deinococcus radiodurans and show that DNA binding does not require i
54 he radiation-resistant bacterium Deinococcus radiodurans and some eukaryotes, Ro has also been implic
55 een the SF1B helicase RecD2 from Deinococcus radiodurans and ssDNA in the presence and absence of an
56 or ECF-derived heat shock sigma factor in D. radiodurans and that it plays a central role in the posi
57 ata indicate that DrII is the RNase II of D. radiodurans and that its structure and catalytic propert
58 the first example of expression of GFP in D. radiodurans and the first detection of GFP in a single b
59 ic sequence analysis showed that Deinococcus radiodurans and Thermus thermophilus do not possess aspa
60 As of Haloarcula marismortui and Deinococcus radiodurans, and the small ribosomal subunit RNA of Ther
61 ing RNAPs from Escherichia coli, Deinococcus radiodurans, and Thermus aquaticus, we show that the fun
62 Yersinia pestis and the other in Deinococcus radiodurans, appear to encode closely related proteins.
65 en exponential-phase cultures of Deinococcus radiodurans are exposed to a 5000-Gray dose of gamma rad
67 peptides (Cys-polypeptides) from Deinococcus radiodurans as well as from mouse B16 melanoma cells.
68 ow that in Synechocystis sp. and Deinococcus radiodurans, as in A. aeolicus, CCA is added by homologo
69 ine, serine, or valine resulted in mutant D. radiodurans AspRS2 enzymes still capable of forming Asp-
70 1 loop of the non-discriminating Deinococcus radiodurans AspRS2 is required for tRNA(Asn) recognition
71 as transformed with DNA from a library of D. radiodurans aspS2 genes with a randomized codon 77 and t
74 ng a photosensory core module of Deinococcus radiodurans bacterial phytochrome (DrBphP-PCM) to the ki
75 he chromophore-binding domain of Deinococcus radiodurans bacterial phytochrome assembled with its chr
76 bining the photosensor module of Deinococcus radiodurans bacterial phytochrome with the effector modu
77 logy and mutational analysis suggest that D. radiodurans bacteriophytochrome functions as a light-reg
79 thin the bilin-binding domain of Deinococcus radiodurans bacteriophytochrome with respect to chromoph
81 ty by a different bacterial NOS (Deinococcus radiodurans) but not by any of the three mammalian NOS o
82 regulates uricase expression in Deinococcus radiodurans by binding a shared promoter region between
84 res of this D207H variant of the Deinococcus radiodurans CBD, in which His-207 is observed to form a
85 ates of D. radiodurans SSB protein in the D. radiodurans cell indicate approximately 2500-3000 dimers
87 o information about such complexes within D. radiodurans cells is lacking, and the idea that they can
88 teins may confer a selective advantage to D. radiodurans cells that aids viability in environments th
89 he radiation-resistant bacterium Deinococcus radiodurans charges tRNA with tryptophan and 4-nitrotryp
90 applications to the analysis of Deinococcus radiodurans chromosome I, of two strains of Helicobacter
94 ing frames for the microorganism Deinococcus radiodurans, consistent with previous results for a spec
95 radiation-resistant eubacterium Deinococcus radiodurans contains an ortholog of an RNA-binding prote
96 ly radiation resistant bacterium Deinococcus radiodurans contains genes for two SSB homologs: the hom
98 he radiation-resistant bacterium Deinococcus radiodurans contains two DNA-binding proteins from starv
99 radiation-resistant eubacterium Deinococcus radiodurans contributes to survival of this bacterium af
100 e expression as stationary phase Deinococcus radiodurans cultures recover from acute exposure to gamm
102 characterized a hemeprotein from Deinococcus radiodurans (D. radiodurans NO synthase, deiNOS) whose s
103 de co-occurrence patterns in the Deinococcus radiodurans, D. geothermalis, and Thermus thermophilus g
104 he radiation-resistant bacterium Deinococcus radiodurans (deiNOS) associates with an unusual tryptoph
106 enced >250 mutations leading to Rif(r) in D. radiodurans derived spontaneously in wild-type and uvrD
110 lease of Fe(2+), the crystal structure of D. radiodurans Dps-1 was determined to 2.0 Angstroms resolu
113 ins of Escherichia coli (Ec) and Deinococcus radiodurans (Dr) both promote a DNA strand exchange reac
116 m the amidohydrolase family from Deinococcus radiodurans (Dr-OPH) with homology to phosphotriesterase
118 lyl-tRNA synthetase) or with the Deinococcus radiodurans DR0705 gene, the ortholog of the MJ1477 gene
120 nt high-resolution structures of Deinococcus radiodurans (Dra)Nramp in multiple conformations to prov
122 f the bacterial phytochrome from Deinococcus radiodurans (DrBphP), which is weakly fluorescent in the
123 Here, we investigate DXPS from Deinococcus radiodurans (DrDXPS), showing that it has similar kineti
126 he radiation-resistant bacterium Deinococcus radiodurans (DrSSB) functions as a homodimer in which ea
128 n that urate is a ligand for the Deinococcus radiodurans-encoded MarR homolog HucR (hypothetical uric
129 utY homolog gene (mutY(Dr)) from Deinococcus radiodurans encodes a 39.4-kDa protein consisting of 363
130 rom the radioresistant bacterium Deinococcus radiodurans encodes three "Helicase and RNase D C-termin
132 tems could provide models to guide future D. radiodurans engineering efforts aimed at integrating sev
134 klandii, Cytophaga hutchinsonii, Deinococcus radiodurans, Escherichia coli, Magnetospirillum magnetot
135 e the Haloarcula marismortui and Deinococcus radiodurans examples, the lower portion of helix 42 in E
136 ein of D. radiodurans is ot detectable in D. radiodurans except in the setting of DNA damage and that
139 synthetase and the lack of this enzyme in D. radiodurans extracts, suggests that the gatCAB genes may
140 s-1 from the radiation-resistant Deinococcus radiodurans fails to protect DNA from hydroxyl radical-m
141 from gene expression studies on Deinococcus radiodurans following DNA damage using cDNA microarrays.
142 eserving the genome integrity of Deinococcus radiodurans following treatment by gamma radiation in an
143 support the prospective use of engineered D. radiodurans for bioremediation of mixed wastes containin
144 terpretations of the capacity of Deinococcus radiodurans for resistance to high doses of ionizing rad
145 t gene clusters could be used to engineer D. radiodurans for treatment of mixed radioactive wastes by
146 Hs from Thermus thermophilus and Deinococcus radiodurans form trimer-of-dimers hexamers in solution,
148 dopyrimidines are preferred substrates of D. radiodurans Fpg protein over 8-OH-Gua, whereas E. coli F
150 ation, combined with the absence from the D. radiodurans genome of genes encoding tRNA-independent as
151 a factors were identified in the Deinococcus radiodurans genome sequence and designated sig1 and sig2
153 (ORFs) from the prerelease version of the D. radiodurans genome were screened for genes more closely
154 how the genome of the bacterium Deinococcus radiodurans gets reassembled after being shattered by hi
155 ed by the inability of the discriminating D. radiodurans GluRS to produce the required mischarged Glu
157 h other Dps proteins, Dps-1 from Deinococcus radiodurans has an extended N terminus comprising 55 ami
158 The MarR homolog, HucR, from Deinococcus radiodurans has been shown to repress expression of a pr
159 ntrachromosomal recombination in Deinococcus radiodurans has been studied recently and has been found
160 -type heat shock sigma factor of Deinococcus radiodurans, has been shown to play a central role in th
161 the radiation-resistant organism Deinococcus radiodurans have been cloned into vectors under the cont
162 s examined, 20 showed topologies in which D. radiodurans homologues clearly group with eukaryotic or
164 mobility shift assays (EMSA), we show that D.radiodurans HU (DrHU) binds preferentially only to DNA j
165 es of proline dehydrogenase from Deinococcus radiodurans in the oxidized state complexed with the pro
166 n DXS, from Escherichia coli and Deinococcus radiodurans, in complex with the coenzyme thiamine pyrop
167 se, an S9C subfamily member from Deinococcus radiodurans, in its active and inactive states at 2.3- a
168 that a bacteriophytochrome from Deinococcus radiodurans, incorporating biliverdin as the chromophore
169 we demonstrate that the RecF of Deinococcus radiodurans interacts with DNA as an ATP-dependent dimer
176 venger of reactive oxygen species, and as D. radiodurans is known for its remarkable resistance to DN
177 We now find that the RecA protein of D. radiodurans is ot detectable in D. radiodurans except in
179 tremely radioresistant bacterium Deinococcus radiodurans is the exact inverse of this established pat
181 cular family member, ISDra2 from Deinococcus radiodurans, is dramatically stimulated upon massive gam
182 ereas DraRnl is inessential for growth of D. radiodurans, its absence sensitizes the bacterium to kil
184 cula marismortui) and bacterial (Deinococcus radiodurans) large ribosomal subunits have been reported
185 Furthermore, detection of DrDps2 in the D. radiodurans membrane fraction suggests that the N-termin
186 y, 10 kGy irradiation causes no change in D. radiodurans Mn(2+) speciation, despite the paucity of ho
189 hemeprotein from Deinococcus radiodurans (D. radiodurans NO synthase, deiNOS) whose sequence is 34% i
190 report that the complex between Deinococcus radiodurans NOS (deiNOS) and an unusual tryptophanyl-tRN
192 knockout disrupting this pathway deprives D. radiodurans of the ability to synthesize asparagine and
194 radiation-resistant eubacterium Deinococcus radiodurans participates in ribosomal RNA (rRNA) degrada
195 putrefaciens, Synechocystis sp., Deinococcus radiodurans, Pasteurella multocida, and Actinobacillus a
196 he chromophore-binding domain of Deinococcus radiodurans phytochrome assembled with its chromophore b
198 rough structural analysis of the Deinococcus radiodurans phytochrome BphP assembled with biliverdin (
199 a 57-kDa photosensory module of Deinococcus radiodurans phytochrome changes from a structurally hete
200 nd computational analyses of the Deinococcus radiodurans phytochrome, we demonstrate that two dimeriz
201 analysis of site-directed mutants in the D. radiodurans phytochrome, we show that this bilin prefere
203 logenetic analysis shows the M. ruber and D. radiodurans prolyl RS to be more closely related to arch
204 te, the bilin chromophore of the Deinococcus radiodurans proteobacterial phytochrome (DrBphP) is hype
211 he radiation-resistant bacterium Deinococcus radiodurans R1 is composed of two chromosomes (2,648,638
213 anscriptional and proteomic profiles of a D. radiodurans R1 sig1 mutant and wild-type cells in respon
214 to facilitate gene disruption in Deinococcus radiodurans R1, has been used to inactivate the gene des
215 Rad54 helicase were reported for Deinococcus radiodurans R1, leading to the speculation that a frames
220 ding and biological functions of DrSSB in D. radiodurans radiation resistance, we have examined the s
221 The unusual DNA pairing properties of the D. radiodurans RecA protein can be explained by postulating
224 results are the first indication that the D. radiodurans RecD protein has a role in DNA damage repair
231 s can be proteolytically removed from the D. radiodurans RecQ (DrRecQ) C terminus, consistent with ea
232 reconstitution of the 10 kGy IR-shattered D. radiodurans replicons that correlates with the timing of
235 s that control DrRecA activity during the D. radiodurans response to gamma radiation exposure are unk
236 ribosomal proteins from H.marismortui and D.radiodurans revealed striking examples of molecular mimi
240 Thermus aquaticus and mesophilic Deinococcus radiodurans RNAPs and identify the FL as an adaptable el
243 We hypothesize that differences between D. radiodurans SSB and homotetrameric bacterial SSB protein
244 mmetry exists between the two OB folds of D. radiodurans SSB because of sequence differences between
246 Extensive crystallographic contacts link D. radiodurans SSB dimers in an arrangement that has import
247 and-double-strand DNA junctions in vitro, D. radiodurans SSB protein has a limited capacity to displa
251 a DNA damage-sensitive strain of Deinococcus radiodurans strain 302 carrying a mutation in an unchara
252 he mutant gene for ddrA157, the resulting D. radiodurans strain became almost as sensitive to gamma r
254 cury (Hg) (II), we have generated several D. radiodurans strains expressing the cloned Hg (II) resist
258 he radiation-resistant bacterium Deinococcus radiodurans suggests the presence of both direct and ind
259 HucR, a novel MarR homolog from Deinococcus radiodurans that demonstrates phenolic sensing capabilit
260 he HspR-like global negative regulator of D. radiodurans that directly represses chaperone and protea
261 the large ribosomal subunit from Deinococcus radiodurans that exploits its association with FLAG-tagg
262 ent, we employ a model system of Deinococcus radiodurans that has been engineered to express GFP unde
263 um albumin and proteins from the organism D. radiodurans that was analyzed using gradient reversed-ph
264 ong most prokaryotes, we derived again in D. radiodurans the rpoB/Rif(r) system that we developed in
265 been characterized primarily in Deinococcus radiodurans, the first sequenced bacterium with a recogn
266 bioremediation strategies using Deinococcus radiodurans, the most radiation resistant organism known
267 l lateral transfer with archaea; Deinococcus radiodurans, the most radiation-resistant microorganism
268 characterization of recombinant Deinococcus radiodurans, the most radiation-resistant organism known
269 In the extremophile bacterium Deinococcus radiodurans, the outermost surface layer is tightly conn
270 and the ICAT-labeled proteome of Deinococcus radiodurans, the presence of these label-specific produc
271 animal cells and the eubacterium Deinococcus radiodurans, the Ro autoantigen, a ring-shaped RNA-bindi
272 In the only studied bacterium, Deinococcus radiodurans, the Ro ortholog Rsr functions in heat-stres
274 teria as t(6)A is dispensable in Deinococcus radiodurans, Thermus thermophilus, Synechocystis PCC6803
275 osome recombination following exposure of D. radiodurans to 1.75 Mrad (17.5 kGy) 60Co, when the plasm
277 he biochemical details of the response of D. radiodurans to ionizing radiation are poorly understood,
279 he radiation-resistant bacterium Deinococcus radiodurans to protect protein epitopes from radiation-i
281 trongly suggest that H(4)F may be used by D. radiodurans to replace H(4)B as a redox-active cofactor
282 remarkable ability of bacterium Deinococcus radiodurans to survive extreme doses of gamma-rays (12,0
283 plasmid that contribute to the ability of D. radiodurans to survive under conditions of starvation, o
285 the 1.75-A crystal structure of Deinococcus radiodurans topoisomerase IB (DraTopIB), a prototype of
287 TrpRS II binds tryptophan (Trp), ATP, and D. radiodurans tRNA(Trp) and catalyzes the formation of 5'
290 OS gene from one such bacterium, Deinococcus radiodurans, was cloned and expressed (deiNOS) in Escher
291 he amidohydrolase superfamily in Deinococcus radiodurans, was cloned, expressed, and purified to homo
292 scuous PLL scaffold (Dr0930 from Deinococcus radiodurans ), we designed an extremely efficient organo
293 nd radiation-resistant bacterium Deinococcus radiodurans, we suggest that the extraordinary radiation
296 g radiation-sensitive strains of Deinococcus radiodurans were evaluated for their ability to survive
297 he radiation-resistant bacterium Deinococcus radiodurans, which is being engineered to express biorem
298 the sHsp system of the bacterium Deinococcus radiodurans, which is resistant against various stress c
299 ults from multiplexed-MS/MS analysis of a D. radiodurans whole cell digest to illustrate the utility