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1 hment rates were over 150-fold compared with random screening.
2 fore enriched the hit rate by 1700-fold over random screening.
3 the model performs significantly better than random screening.
4 cially available molecules is preferred over random screening.
5 le could offer pivotal guidance to otherwise random screenings.
8 s enrichment is greater than that found with random screening and docking to three-dimensional struct
10 vious efforts to develop AS inhibitors using random screening approaches, and that all of the ionizab
13 rically, most antibiotics were discovered by random screening campaigns, but over the past 20 years,
16 ts were discovered through optimization of a random screening hit, a p-(alpha-methylbenzyloxy)cinnami
17 g both site-directed mutagenesis and in vivo random screening in the yeast three-hybrid binding assay
18 m of 3- to 4-fold enrichment in actives over random screening is observed even though the actives ide
20 human cytomegalovirus protease identified by random screening of a chemical library was 1,4-dihydro-7
21 ces that matched two cDNA clones obtained by random screening of a peppermint-oil gland cDNA library.
29 y be traced to a lead compound identified by random screening that was initially modified by incorpor
30 and least similar hit-to-clinical pairs from random screening were examined to provide perspective on