ライフサイエンスコーパス: randomize

1 A total of 304 patients were randomized.

2 In total, 1027 patients were randomized.

3 Prescribers were randomized 1:1 to either a 12-month intervention consist

4 Participants were randomized 1:1 to receive 2 intramuscular injections 28

5 Patients were randomized 1:1 to receive 25 mg clazakizumab or placebo

6 randomized, controlled trial; subjects were randomized 1:1 to receive either BAT plus optimal medica

7 e outcome of patients with confirmed NSTEACS randomized 1:1 to very early (within 12 h) or standard (

8 Patients (n=448) were randomized 1:1:1 to placebo, 25 mg of OM BID, or to phar

9 Participants were randomized (1:1 ratio) to a strategy of antihypertensive

10 response to intranasal corticosteroids were randomized (1:1) to omalizumab or placebo and intranasal

11 We randomized 100 healthy adults to receive morphine versus

12 Of 40 participants who were randomized, 17 dipyridamole and 18 placebo recipients ha

13 Participants were randomized 2:1 to FAi or sham (injection plus standard o

14 After phacoemulsification, eyes were randomized 2:1 to receive a Hydrus Microstent or no sten

15 lds (N=148) into four age-descending groups, randomized 2:1 to receive two doses of TAK-003 or placeb

16 Between August 2016 and April 2018, we randomized 24 adults with obesity and mild-moderate insu

17 Patients were randomized 3:2 to suprachoroidally injected CLS-TA or sh

18 Patients were randomized 3:3:3:2 to treatment with the PDS filled with

19 omized, 3184 analyzed) with BCG-Russia (3170 randomized, 3160 analyzed).

20 continued comparing BCG-Japan (3191 neonates randomized, 3184 analyzed) with BCG-Russia (3170 randomi

21 We randomized 40 SCZ non-smokers into a double-blind clinic

22 We randomized 75 healthy, female, adult volunteers to recei

23 Among 980 patients who were randomized, 969 (99%) completed the trial (median age, 6

24 Of the 200 randomized, 98 received RT and 102 LBT.

25 In this randomized, active-controlled, double-blinded trial, 444

26 This is a randomized and double-blind clinical trial to evaluate t

27 fty participants (median age 7.3 years) were randomized and initiated treatment.

28 Randomized and observational studies consistently demons

29 Randomized and observational studies demonstrate pitolis

30 d macular degeneration in the study eye were randomized and treated in HAWK/HARRIER.

31 One hundred twenty-five patients were randomized and treated.

32 A total of 201 patients were randomized, and 199 received >=1 dose of study treatment

33 716 adults screened for the study, 558 were randomized, and 501 were confirmed to have influenza.

34 ither leaflet resection or preservation were randomized at 7 specialized cardiac surgical centers.

35 h speaking, consented to follow-up, and were randomized between December 11, 2017, and May 4, 2018 (n

36 tients randomized by site to PPIs and 13 392 randomized by site to H2RBs).

37 H2RBs and then use of PPIs (13 436 patients randomized by site to PPIs and 13 392 randomized by site

38 respecified analysis of the ODYSSEY OUTCOMES randomized clinical trial (Evaluation of Cardiovascular

39 D PARTICIPANTS: Multicenter, double-blinded, randomized clinical trial at 20 trauma centers and 39 em

40 DESIGN, SETTING, AND PARTICIPANTS: Randomized clinical trial at 39 DRCR Retina Network site

41 SIGN, SETTING, AND PARTICIPANTS: Open-label, randomized clinical trial conducted at 17 UK hospitals.

42 DESIGN, SETTING, AND PARTICIPANTS: Randomized clinical trial conducted at 22 endocrinology

43 DESIGN, SETTING, AND PARTICIPANTS: A randomized clinical trial conducted at 24 trauma hospita

44 igator-initiated, multicenter, single-blind, randomized clinical trial conducted at 5 referral center

45 N, SETTING, AND PARTICIPANTS: Noninferiority randomized clinical trial conducted from October 26, 201

46 Six-month double-blind, randomized clinical trial in which participants with PAD

47 : Multicenter, noninferiority, point-of-care randomized clinical trial including adults hospitalized

48 ry PTSD diagnosis (N = 66) participated in a randomized clinical trial of prolonged exposure therapy

49 We conducted a randomized clinical trial of text messaging (TM) versus

50 report negative results on a randomized clinical trial testing the combination of apr

51 cagrelor in Peripheral Artery Disease) was a randomized clinical trial that assigned patients with pe

52 of samples from an intrapartum azithromycin randomized clinical trial, we found that children whose

53 of patients (n = 116) enrolled in 3 phase-3 randomized clinical trials (AMAGINE -1 [Efficacy, Safety

54 ic search was performed to identify eligible randomized clinical trials (RCTs) reporting on the chang

55 Numerous randomized clinical trials have demonstrated the superio

56 this systematic review and meta-analysis of randomized clinical trials of patients with primarily no

57 re included in this review, of which 12 were randomized clinical trials of therapy that included 3074

58 Randomized clinical trials support the efficacy of MDMA

59 We conducted a meta-analysis of ten randomized clinical trials to evaluate the efficacy and

60 Fourteen randomized clinical trials were eligible for inclusion (

61 low-risk populations, in properly designed, randomized clinical trials, although data on the long-te

62 In this meta-analysis of randomized clinical trials, blood pressure lowering with

63 tes into 2 identically designed, open-label, randomized clinical trials.

64 stemsavir plus optimized background therapy (randomized cohort).

65 In the randomized cohort, glycoprotein 120 (gp120) substitution

66 her frequency of nearby premises compared to randomized configurations.

67 scoops, child potties delivered as part of a randomized control trial, WASH Benefits) in rural Bangla

68 analysis of risk and benefit will require a randomized control trial.

69 This phase 4, multicenter, open-label, randomized, control trial enrolled 360 children who were

70 Randomized controlled studies were utilized when availab

71 This randomized controlled study shows that a 45 W radiofrequ

72 The authors conducted a randomized controlled telemedicine trial of CBT-guided s

73 In an open-label, randomized controlled trial (RCT), consecutive patients

74 A 1-y randomized controlled trial [New Dietary Strategies Addr

75 We identified 17 studies (6 randomized controlled trial [RCT], 5 cohorts, and 6 case

76 VF patency, we performed an observer-blinded randomized controlled trial at three university hospital

77 A randomized controlled trial comparing mBCG and RC will b

78 These are secondary analyses of a randomized controlled trial in rural Malawi.

79 Ultimately, a randomized controlled trial is needed, examining effects

80 al meningitis using clinical isolates from a randomized controlled trial of antifungal treatment (amp

81 umber NCT03702582Rationale and Design of the Randomized Controlled Trial of New Oral Anticoagulants v

82 In the DIRECT PLUS (Dietary Intervention Randomized Controlled Trial Polyphenols-Unprocessed) wei

83 A recent multicenter, international randomized controlled trial showed that DOF following a

84 Findings from this exploratory analysis of a randomized controlled trial support further investigatio

85 19 should be prospectively investigated in a randomized controlled trial to ascertain the extent of r

86 This randomized controlled trial was primarily aimed at testi

87 Largely based on one randomized controlled trial, standard dose of epinephrin

88 vents and self-rated health in a multicenter randomized controlled trial.

89 sty; NCT01121224) prospective, double-blind, randomized controlled trial.

90 bel, two-arm, non-inferiority, multi-center, randomized controlled trial.

91 d and the Cochrane Library were searched for randomized controlled trials (RCTs) and meta-analyses of

92 d and the Cochrane Library were searched for randomized controlled trials (RCTs) and systematic revie

93 We systematically identified randomized controlled trials (RCTs) investigating the sa

94 lower than dictated by the protocol in many randomized controlled trials and negative results may re

95 Randomized controlled trials and prospective observation

96 Randomized controlled trials are needed to determine the

97 Our findings indicate the impact that randomized controlled trials can have on real-world prac

98 c analysis on 1,047 patients with PDD from 2 randomized controlled trials comparing rivastigmine vers

99 infants remains lacking; adequately powered randomized controlled trials evaluating probiotic supple

100 Randomized controlled trials examining the impact of sel

101 prove biologic plausibility and causality as randomized controlled trials have not been performed.

102 Randomized controlled trials including the use of either

103 servational study using data from four large randomized controlled trials investigating different pre

104 d risk of acute respiratory infection (ARI), randomized controlled trials of vitamin D supplementatio

105 All 29 randomized controlled trials that were included had no r

106 otics that have already been tested in human randomized controlled trials, most of these potential th

107 or 53 (93%) of the vaccines was supported by randomized controlled trials, with a median cohort size

108 es: a systematic review and meta-analysis of randomized controlled trials.

109 Two-thirds of the included studies were randomized controlled trials.

110 month, multicenter, multinational, parallel, randomized controlled, non-inferiority trial in 108 part

111 In AUGUSTUS (Open-Label, 2x2 Factorial, Randomized, Controlled Clinical Trial to Evaluate the Sa

112 In this randomized, controlled pilot trial, a post-debridement s

113 edicine and Public Health (NSIGHT2) study, a randomized, controlled trial of rapid diagnostic genomic

114 We performed a randomized, controlled trial to investigate the effects

115 This was an open-label, parallel-group, randomized, controlled trial.

116 ilure) trial was a multicenter, prospective, randomized, controlled trial; subjects were randomized 1

117 ured process to design RWE studies emulating randomized, controlled trials (RCTs) and compare results

118 The RCT DUPLICATE initiative (Randomized, Controlled Trials Duplicated Using Prospecti

119 Randomized, controlled trials evaluating the clinical ef

120 pon injury might explain results from large, randomized, controlled trials in which improved renal ou

121 Randomized, controlled trials of hydroxychloroquine in p

122 The trial was a randomized, controlled, crossover, intervention study.

123 The aim of this prospective randomized-controlled trial was to evaluate the risks/be

124 We conducted a randomized, cross-over trial in consecutive patients wit

125 This is a prospective, non-randomized, cross-sectional study of 80 neurocritical ca

126 Using a double-blind, placebo-controlled, randomized crossover design, nontreatment seeking smokin

127 This randomized crossover trial in Quetzaltenango, Guatemala

128 The randomized DAPA trial (Defibrillator After Primary Angio

129 However, long-term randomized data that test this paradigm are lacking.

130 A phase 1-2 randomized double-blind placebo-controlled trial enrolle

131 SIGN, SETTING, AND PARTICIPANTS: Multicenter randomized double-blind sequential trial conducted in Fr

132 In a randomized double-blind, placebo-controlled, time course

133 We conducted a randomized double-blinded placebo-controlled trial to de

134 omalizumab versus placebo to asthmatics in a randomized, double-blind placebo-controlled investigatio

135 TARGET was a randomized, double-blind, active-controlled, parallel-gr

136 rRus and INcreased Cardiovascular RisK) is a randomized, double-blind, multinational trial comparing

137 IGN, SETTING, AND PARTICIPANTS: Multicenter, randomized, double-blind, parallel-group trial conducted

138 In this randomized, double-blind, phase 3 trial, we assigned, in

139 reatment with empagliflozin and placebo in a randomized, double-blind, placebo-controlled crossover s

140 This single-center, phase 2, randomized, double-blind, placebo-controlled study inves

141 This was a randomized, double-blind, placebo-controlled trial in wh

142 This randomized, double-blind, placebo-controlled trial inclu

143 FOURIER was a randomized, double-blind, placebo-controlled trial invol

144 A factorial, randomized, double-blind, placebo-controlled trial was c

145 We conducted a randomized, double-blind, placebo-controlled, dose-rangi

146 A randomized, double-blind, placebo-controlled, two-way cr

147 We conducted a multisite, randomized, double-blinded, controlled trial to examine

148 A randomized, double-blinded, placebo-controlled, crossove

149 Women were randomized during their second trimester to blinded week

150 esponse, two phosphorylation pathways, and a randomized gene sets.

151 Furthermore, using seed site randomized genomes and evolutionary selection experiment

152 ed stage-adapted first-line treatment in the randomized GHSG HD7 to HD15 studies was investigated.

153 in lymphoma-directed first-line treatment in randomized GHSG trial protocols was good.

154 IRF and PFA deliveries were randomized in 8 dogs with 2 superior PVs ablated using o

155 9 patients (age range, 4-17 years) initially randomized in the 4-month VErnal KeratoconjunctiviTIs St

156 A total of 362 participants were randomized in the Study of Comparative Treatments for Re

157 s a liquified petroleum gas (LPG) fuel/stove randomized intervention trial enrolling 800 pregnant wom

158 Participants were randomized into 3 groups: control, reference chart only,

159 center, parallel-group, double-blind RCT and randomized into 4 arms (n = 23): HP-diet and beta-crypto

160 A total of 130 participants were randomized into 5 groups.

161 ese, black South African women (n = 45) were randomized into exercise (n = 23) or control (n = 22) gr

162 Overall, 12,485 individuals were randomized into the 3 study groups.

163 -specified subgroups of UA and NSTEMI of the randomized ISAR-REACT 5 trial.

164 median angiographic diameter stenosis of the randomized lesions was 41.6%; by near-infrared spectrosc

165 Comparative randomized long-term studies are needed.

166 ange of severity of FECD were evaluated in a randomized manner for the presence of 3 tomographic feat

167 In trial A, 123 patients were randomized (mean [SD] age, 45.1 [11.0] years; 95.9% wome

168 Of 152 patients who were randomized (mean [SD] age, 46 [13] years; 109 [72%] wome

169 who underwent a major hepatic resection were randomized (mean age = 62.8 years; 57% male; body-mass-i

170 Of the 1624 women randomized (mean age, 30.4 years, mean body mass index,

171 Among 352 patients randomized (mean age, 62.2 [SD, 17.7] years; 121 women [

172 Among 330 patients who were randomized (mean age, 68 years; 181 [55%] women), 320 (9

173 Of 44 PAD participants randomized (mean age, 72.3 years [+/-7.1]; mean ankle br

174 Among 479 patients who were randomized (median age, 57 years; 44.3% female; 37.2% Hi

175 zed as secondary outcomes of a double-blind, randomized, milk-based vitamin D intervention trial cond

176 SETTING, AND PARTICIPANTS: A parallel-group, randomized multicenter clinical trial in 26 centers acro

177 We designed an open-label, randomized, multicenter, two-arm phase II trial to inves

178 We conducted a randomized, observer-blind, comparator-controlled (triva

179 G4 and hypertension, we conducted a 6-week, randomized, open-label crossover trial comparing amilori

180 cin ING is a noncomparative, active-control, randomized, open-label study in HIV-1-infected antiretro

181 In an update of the randomized, open-label, phase III European Mantle Cell L

182 Of 813 randomized participants (mean [SD] age, 66.5 years [8.2

183 We included 159 randomized participants in the modified intention-to-tre

184 Among 294 randomized participants, 292 (99%) were included in the

185 Of the 343 randomized patients (mean [SD] age, 66.5 [9.7] years; 26

186 A total of 36 randomized patients received ASP4345 (3, 15, 50, and 150

187 nist in Type 2 Diabetes (MIRAD) trial, which randomized patients to either high-dose eplerenone or pl

188 ization or Not in Intermittent Claudication) randomized patients with mild-to-severe intermittent cla

189 in patients with NPM1mut AML enrolled in the randomized phase 3 AMLSG 09-09 trial.

190 We used a randomized phase II screening design with a primary end

191 ate into an overall survival (OS) benefit in randomized phase III trials.

192 We conducted an open-label, international, randomized, phase 3 trial involving patients younger tha

193 2019 (COVID-19) is currently being tested in randomized placebo-controlled clinical trials.

194 FMT-TRIM was a 12-week double-blind randomized placebo-controlled pilot trial of oral FMT ca

195 We conducted a 24-wk randomized placebo-controlled trial in 126 overweight, n

196 SHIFT was a randomized placebo-controlled trial investigating the ef

197 iological and laboratory studies, as well as randomized placebo-controlled trials, suggests supplemen

198 ta, taken together, highlight the need for a randomized, placebo-controlled efficacy trial (1) to def

199 As part of the Women's Health Initiative, randomized, placebo-controlled hormone therapy trials of

200 We conducted a double-blind, randomized, placebo-controlled noninferiority trial invo

201 We conducted a multicenter, two-group, randomized, placebo-controlled trial in nine hospitals i

202 In part 1 of this phase 2, randomized, placebo-controlled trial we sequentially enr

203 To fill this gap, we conducted a randomized, placebo-controlled, double-blind pharmacolog

204 Part 1 was a double-blind, randomized, placebo-controlled, single ascending dose st

205 tal of 7 studies with 8 group comparisons (3 randomized) representing 503 women (250 PN; 253 Control)

206 burst transcranial magnetic stimulation in a randomized, sham-controlled design.

207 In the present double-blind, randomized, sham-controlled trial, 105 patients with rec

208 d device-based therapy for hypertension, and randomized, sham-controlled trials have provided proof-o

209 Prospective randomized single-center trial.

210 CORDIOPREV) study is an ongoing prospective, randomized, single-blind, controlled trial in 1,002 coro

211 iated, National Institutes of Health-funded, randomized, single-blinded trial conducted in 12 centers

212 n Organ Transplantation-09 study in which we randomized stable kidney transplant recipients to Tac wi

213 Future randomized studies are warranted.

214 Using a matched-pair cluster randomized study design (ClinicalTrials.gov: NCT02776254

215 Baseline to month 24 data from all randomized study eyes in HARBOR with both FFA and SD OCT

216 of 90 patients (86%) included in the initial randomized study were deceased at the end of 2017.

217 In the randomized survey, only respondents who viewed a note in

218 ealthy adult participants were recruited and randomized to (I) IDA alone, (II) IDA combined with AZI,

219 Participants were randomized to 1 of 4 sunscreen products, formulated as l

220 Study eyes were randomized to 1 of 4 treatment combinations using an ada

221 Participants were randomized to 1200 mg daily of ALA or placebo.

222 A 4-5; n = 121) reporting URTI symptoms were randomized to 14 days of once-daily nebulized AZD9412 or

223 rospective trial, participants with DM1 were randomized to a behavioral intervention (n = 14) or cont

224 osed with HRS acute kidney injury (AKI) were randomized to albumin with infusion of terlipressin (2-1

225 rimental medicine study, healthy adults were randomized to an FAAH inhibitor (PF-04457845, 4 mg orall

226 lic parameters in HIV-uninfected individuals randomized to cabotegravir or a placebo.

227 68 piglets were randomized to cardiac arrest or sham procedure with cont

228 In total, 679 patients were randomized to ceftobiprole (n = 335) or vancomycin/aztre

229 ne furoate nasal spray run-in, patients were randomized to commence subcutaneous dupilumab (600 mg lo

230 Those randomized to CXL regardless of medication (topical nata

231 ren with recurrent asthma-like symptoms were randomized to either a 3-day course of oral azithromycin

232 al trial in which participants with PAD were randomized to either cocoa beverage versus placebo bever

233 ficant difference in OS in favor of patients randomized to eribulin compared with control in patients

234 In 2014, 117 programs were randomized to flexible or standard duty-hour policy.

235 ative, non-pregnant Rwandan BV patients were randomized to four groups (n = 17/group) after seven-day

236 calTrials.gov: NCT02776254), 10 clinics were randomized to intervention (5 clinics) or control (5 cli

237 Two hundred and twenty subjects were randomized to NSI-189 40 mg daily, 80 mg daily, or place

238 etinal Vein Occlusion 2, and 88 participants randomized to observation in the Standard Care vs Cortic

239 ility received an optimized regimen and were randomized to omit or add NRTIs.

240 6 months; cohort 3: > 1 to < 3 months) were randomized to oral JNJ-8678 or placebo once daily for 7

241 3 to 10 cm on computed tomography scan) were randomized to PFC versus bridged repair.

242 ion days (95% CI, 0 to 18.05), and residents randomized to placebo had a mean of 12.0 days (95% CI, 0

243 s after the de-obstruction, REL animals were randomized to rapamycin (REL+rapa) or vehicle (REL+veh).

244 ealthy adults (18-55 years of age), who were randomized to receive 2 doses-separated by 21 days-of 10

245 ruary 2018, a total of 170 participants were randomized to receive 6 monthly injections of either 1.2

246 Study participants were randomized to receive 960 mg of oral co-trimoxazole twic

247 Thirty-six patients were randomized to receive a collagen sponge with or without

248 trial enrolled 360 children who were equally randomized to receive a single dose of either JENVAC or

249 uble-blind clinical trial, participants were randomized to receive either 150 mg/d of resveratrol (n

250 , 444 adults 60 through 64 years of age were randomized to receive either a single dose of PCV20 foll

251 Overall, 394 KT recipients were randomized to receive immediate (N = 197) or delayed (N

252 through February 2018, 277 participants were randomized to receive injections of 1.25 mg bevacizumab

253 resistance mediated by an inhA mutation were randomized to receive isoniazid 5, 10 or 15 mg/kg daily

254 Patients were randomized to receive LAAC or DOAC.

255 Patients with nonischemic HF were randomized to routine versus selective CMR.

256 RT-naive participants from the ADVANCE study randomized to the efavirenz /emtricitabine/tenofovir dis

257 One hundred thirty-one patients were randomized to the ICD arm and 135 patients to the contro

258 maximum-tolerated statin treatment who were randomized to the PCSK9 inhibitor alirocumab or placebo.

259 Care home residents randomized to the probiotic group had a mean of 12.9 cum

260 PPIs and then use of H2RBs and 25 ICUs were randomized to the sequence with use of H2RBs and then us

261 y for 6 months in random order; 25 ICUs were randomized to the sequence with use of PPIs and then use

262 F with moderate-to-severe or severe SMR were randomized to TMVr with the MitraClip plus guideline-dir

263 Subjects were randomized to treatment of the six most involved airways

264 sel and/or left main coronary artery disease randomized to treatment with PCI or CABG in the SYNTAX t

265 urred from November 2011 through March 2014; randomized treatment ended on December 31, 2017, and thi

266 This multicenter randomized trial aimed at objectifying the effect of abd

267 lusions should be confirmed in a prospective randomized trial before firm recommendations regarding c

268 omes) was a double-blind, placebo-controlled randomized trial conducted from 2008 to 2012 over a medi

269 In this randomized trial conducted in the public health care sys

270 In a cluster-randomized trial in 26 Ugandan fishing communities we in

271 In a randomized trial of patients undergoing EUS-FNA for panc

272 In a randomized trial of patients with NAFLD, 1 year of admin

273 In A Randomized trial of Unruptured Brain Arteriovenous malfo

274 potential risk factors among a subset of the Randomized Trial to Prevent Vascular Events in HIV (REPR

275 We conducted a cluster-randomized trial to test the effectiveness of a high-int

276 icoagulation enrolled in the Evolut Low Risk randomized trial underwent computed tomographic imaging

277 ute Stroke Services) was a pragmatic cluster-randomized trial where the hospital was the unit of rand

278 We conducted a randomized trial with 40 children aged 4-15 years at the

279 In a phase 2 randomized trial, we found that addition of NAPs to TDF

280 3 y; BMI: 23 +/- 2) participated in a 2 x 2 randomized trial.

281 ing the performance of an adequately powered randomized trial.

282 A meta-analysis was conducted from randomized trials (2001-2020) that studied discontinuati

283 tion for sample size calculations of cluster-randomized trials and household surveys, and inform the

284 More randomized trials are urgently needed to address importa

285 Several randomized trials demonstrated that chemoprophylaxis, or

286 Mendelian randomization studies and randomized trials have conclusively demonstrated that lo

287 Randomized trials of BP pharmacologic treatment (more in

288 ed Trials, MEDLINE, and Embase databases for randomized trials of eHealth interventions in solid orga

289 In 2 randomized trials of patients with iron-deficiency anemi

290 Four registered randomized trials plan to evaluate ACEIs and ARBs for tr

291 We estimated transition probabilities from randomized trials using parametric survival modeling.

292 on of clinical efficacy would require larger randomized trials with more definitive outcome measures.

293 c disease have not been proven successful in randomized trials, but the quantity of early-life gluten

294 ved and currently is being tested in ongoing randomized trials.

295 prevention in men was demonstrated in three randomized trials.

296 PDAC and warrants confirmation in subsequent randomized trials.

297 e-blind, parallel-group, enriched enrollment randomized withdrawal trial conducted at the Medical Uni

298 e 3 multicenter, double-blind, event-driven, randomized-withdrawal trial of rilonacept in patients wi

299 cted or confirmed COVID-19 were enrolled and randomized within at least 1 domain following admission

300 Patients were randomized within the first 24 hours from intubation to