ライフサイエンスコーパス: randomized trial

1 study contemporaneous to a partner-enrolled randomized trial.

2 o Reduce HIV Transmission (PopART) community-randomized trial.

3 tial value and challenges of a sham ablation randomized trial.

4 oronary artery bypass grafting in a blinded, randomized trial.

5 3 y; BMI: 23 +/- 2) participated in a 2 x 2 randomized trial.

6 2 Study (NEAT022) is a European, open-label, randomized trial.

7 ing the performance of an adequately powered randomized trial.

8 d demonstrated efficacy in a 6-month cluster-randomized trial.

9 y exploratory interim analysis of an ongoing randomized trial.

10 supporting the testing of this strategy in a randomized trial.

11 al breast tumor recurrence (IBTR) in a large randomized trial.

12 eriod) was followed by a three-month cluster-randomized trial.

13 xamine TBE in a single-blind, sham procedure randomized trial.

14 treatment trial and the stepped-wedge group-randomized trial.

15 warrants further evaluation in a multicenter randomized trial.

16 C after LT was investigated in a prospective randomized trial.

17 hese data provide the scientific basis for a randomized trial.

18 PDAC and warrants confirmation in subsequent randomized trials.

19 ovations in the design and analysis of group-randomized trials.

20 ain probiotics in a network meta-analysis of randomized trials.

21 ork meta-analysis of 52 816 patients from 12 randomized trials.

22 nd data from uncontrolled studies and small, randomized trials.

23 nt provides minimum guidelines for reporting randomized trials.

24 oagulation therapy, require investigation in randomized trials.

25 conditioning regimen has not been studied in randomized trials.

26 ved and currently is being tested in ongoing randomized trials.

27 FADS1 genotype needs to be tested in larger randomized trials.

28 prevention in men was demonstrated in three randomized trials.

29 ower risk of cancer than in meta-analyses of randomized trials.

30 ry, supratentorial IPH are being explored in randomized trials.

31 stematic review and network meta-analysis of randomized trials.

32 ese data will provide a basis to plan future randomized trials.

33 , as they have not been compared directly in randomized trials.

34 There were no randomized trials, 11 time-series studies, 1 retrospecti

35 A meta-analysis was conducted from randomized trials (2001-2020) that studied discontinuati

36 this 4-mo, double-blind, placebo-controlled, randomized trial, 244 women (45-65 y) participated in a

37 As evidenced by multiple randomized trials, AF catheter ablation can reduce the r

38 This multicenter randomized trial aimed at objectifying the effect of abd

39 e I/II prospective, open label, multicenter, randomized trial aimed primarily at evaluating the safet

40 This randomized trial aimed to investigate the nonspecific im

41 and FGF23 in stage 3b/4 CKD, we conducted a randomized trial among individuals with eGFR 20-45 ml/mi

42 Individual patient data from 2 randomized trials and 13 PSM studies involving 3148 part

43 The review included 37 randomized trials and 2 nonrandomized controlled interve

44 tion for sample size calculations of cluster-randomized trials and household surveys, and inform the

45 t they still lag behind parallel-arm cluster-randomized trials and individually randomized trials in

46 Most recent meta-analyses of randomized trials and observational studies found no ben

47 trum and consistency of outcomes reported in randomized trials and observational studies in living ki

48 Electronic databases were searched for randomized trials and observational studies reporting ou

49 learly established by consistent findings of randomized trials and observational studies; that animal

50 eview focuses on the available evidence from randomized trials and proposes a design for future clini

51 Randomized trials and PSM studies constitute the highest

52 mework clarifies the findings of large-scale randomized trials and the close association of ketogenes

53 ic bypass are limited by low sample size (in randomized trials) and selection bias (in observational

54 men on the basis of immunogenicity data from randomized trials, and limited data suggest that even 1

55 lti-center, double-blind, placebo-controlled randomized trial (ANZCTR:12607000144415).

56 In a harmonized dataset of 4 multicenter randomized trials (APPRAISE-2 [Apixaban for Prevention o

57 Evidence from randomized trials are difficult to obtain, particularly

58 However, data from randomized trials are limited.

59 up treated surgically for bicuspid stenosis, randomized trials are needed to adequately assess the ef

60 Well-powered randomized trials are needed to conclusively address ris

61 Further well-designed randomized trials are needed to demonstrate whether (min

62 Given the observed bleeding rates, randomized trials are needed to determine any potential

63 However, further prospective randomized trials are needed to determine the optimal me

64 Randomized trials are needed to determine which cow-milk

65 Randomized trials are required to determine the optimal

66 Adequately powered randomized trials are required to evaluate the outcomes

67 Randomized trials are required to examine whether modera

68 More randomized trials are urgently needed to address importa

69 Randomized trials are warranted to provide a higher qual

70 This randomized trial assessed whether rituximab intensificat

71 However, randomized trials assessing the impact of long-term noni

72 Single-blinded parallel-group randomized trial at 12 international American College of

73 one oxytocin to the same 57 individuals in a randomized trial before conducting the RHI.

74 lusions should be confirmed in a prospective randomized trial before firm recommendations regarding c

75 owing T-cell-depleting induction in a recent randomized trial (Belatacept-based Early Steroid Withdra

76 s also essential to extend the evidence from randomized trials beyond the narrow range of settings an

77 -savings favour intermittent therapy in most randomized trials, but the benefit for clinical practice

78 c disease have not been proven successful in randomized trials, but the quantity of early-life gluten

79 ent nested within a population-based cluster-randomized trial comparing a nutrition counseling and mi

80 1-98 is a four-arm, phase III, double-blind, randomized trial comparing adjuvant letrozole versus tam

81 ted a pragmatic, nonblinded, noninferiority, randomized trial comparing antibiotic therapy (10-day co

82 ies over time; BP MAP will conduct a cluster-randomized trial comparing effectiveness of 2 versions o

83 ome will conduct an individual patient-level randomized trial comparing effectiveness of smartphone-l

84 l outcomes; however, further evidence from a randomized trial comparing immediate with delayed surger

85 We conducted a randomized trial comparing real-world case notification

86 he SVG as the second conduit and the largest randomized trial comparing the use of single and bilater

87 We wanted to understand whether a randomized trial comparing these options was possible.

88 A systematic review identified published randomized trials comparing EBRT with or without ADT, or

89 These results highlight the urgent need for randomized trials comparing OAC versus APT post-LAAC.

90 l Register of Controlled Trials searches for randomized trials comparing routine revascularization ve

91 Recently, a pooled analysis of 6 randomized trials comparing the radial artery with the S

92 Randomized trials comparing the same treatment regimens

93 s a multicenter, blinded, placebo-controlled randomized trial conducted at 34 hospitals in the US.

94 omes) was a double-blind, placebo-controlled randomized trial conducted from 2008 to 2012 over a medi

95 In the HPTN 071 (PopART) community-randomized trial conducted from 2013 through 2018, we ra

96 SIGN, SETTING, AND PARTICIPANTS: Multicenter randomized trial conducted from February 8, 2017, throug

97 nt models for OAT patients using data from a randomized trial conducted in Bronx, New York.

98 In this randomized trial conducted in the public health care sys

99 se results, based on an IPD meta-analysis of randomized trials, confirm the benefit of ExCR on HRQoL

100 Cluster-randomized trials (CRTs) are able to address research qu

101 These exploratory analyses of randomized trial data provide proof of principle that in

102 Observational and randomized trial data reporting outcomes for >5 patients

103 Randomized trials demonstrate no benefit from antibiotic

104 Randomized trials demonstrate that salt reduction lowers

105 A randomized trial demonstrated that among people living w

106 A randomized trial demonstrated that fetal spina bifida (S

107 Several randomized trials demonstrated that chemoprophylaxis, or

108 Rationale: We reported a randomized trial demonstrating daily supplemental vitami

109 STRIVE was a phase 2, double-blind, randomized trial designed to compare the safety and effi

110 n adults in the published literature nor any randomized trials designed to examine this association.

111 The COMS randomized trial documented the absence of a clinically

112 prematurely terminated and thus underpowered randomized trial, early prophylactic ICD implantation de

113 itiated, double-blinded, placebo-controlled, randomized trial enrolled 70 patients with HFrEF from Ma

114 Randomized trials established the superiority of ibrutin

115 SHINE is a randomized trial evaluating shorter treatment in 1,204 c

116 edings (1990-2018) were searched to identify randomized trials evaluating the sequencing, but not dur

117 imply causation, and there was a paucity of randomized trial evidence addressing long-term safety of

118 ir approval, there has been no real-world or randomized trial evidence evaluating the effect of the a

119 e, and summarize recent meta-analyses of the randomized trial evidence on these agents.

120 alculated by applying treatment effects from randomized trials for a 1-year time horizon.

121 important, such as in the design of cluster randomized trials for studying interventions for infecti

122 This randomized trial found that cultural integration signale

123 We performed a cluster-randomized trial from October-November 2015 at the Unive

124 ctive studies (18 cohorts, 3 case-cohorts, 4 randomized trials) from the GENIUS-CHD (Genetics of Subs

125 For two stimulation targets, pivotal randomized trials have been conducted; both failed a fut

126 Few randomized trials have compared bioprostheses for transc

127 Mendelian randomization studies and randomized trials have conclusively demonstrated that lo

128 Previous randomized trials have generated low- to moderate-streng

129 adjuvant therapy, although data from several randomized trials have shown improved outcomes with neoa

130 Randomized trials have shown that initiating breast canc

131 ING, AND PARTICIPANTS: Stepped-wedge cluster randomized trial in 15 EDs in France of 503 patients 75

132 In a cluster-randomized trial in 26 Ugandan fishing communities we in

133 We conducted a pair-matched, community-randomized trial in 30 rural or periurban communities in

134 We conducted a pragmatic randomized trial in a large integrated healthcare delive

135 In a randomized trial in adults assigned to 1 of 6 treatment

136 we conducted a parallel-group, double-blind, randomized trial in participants aged 18 or older with C

137 This was a phase III randomized trial in patients with advanced NSCLC harbori

138 r, 8-week, double-blind, placebo-controlled, randomized trial in patients with anhedonia and a mood o

139 In a pilot randomized trial in persons with opioid use disorder hos

140 h cohort study nested within a large cluster-randomized trial in the Republic of Belarus, that had re

141 h cohort study nested within a large cluster-randomized trial in the Republic of Belarus, with repeat

142 We conducted a multicenter, randomized trial in the United Kingdom that enrolled adu

143 ventional chemotherapy was not achieved in a randomized trial in this setting.

144 con Dieta Mediterranea) cohort, originally a randomized trial in which participants followed a Medite

145 educes left ventricular mass, we conducted a randomized trial in which patients received either low-s

146 In this randomized trial in which patients with peripheral arter

147 m cluster-randomized trials and individually randomized trials in achieving adequate power to detect

148 The external validity of multicenter randomized trials in cancer treatment has been criticize

149 Randomized trials in children show inconsistent effects

150 Randomized trials in community settings found possibly n

151 n in HIV preexposure prophylaxis studies and randomized trials in persons without HIV.

152 Randomized trials in the operating room have demonstrate

153 There were 68 randomized trials included in the systematic review, of

154 We conducted post-hoc analysis of two randomized trials including 6859 adult participants with

155 th prior surgical results, in the context of randomized trials including the left main (LM) coronary

156 Evidence from meta-analyses of randomized trials indicates that self-measured BP monito

157 Incorporating randomized trials into dialysis clinical care delivery s

158 for Promotion of Health) study is a cluster-randomized trial involving 15 Head Start preschools in H

159 In this phase-3, randomized trial involving 756 adults with stage-3 to -5

160 We conducted an open-label, cluster-randomized trial involving asymptomatic contacts of pati

161 In a randomized trial involving patients with chronic coronar

162 We conducted a multicountry, randomized trial involving pregnant women between 26 wee

163 Randomized trials involving patients with stroke have es

164 In an open, cluster-randomized trial (ISRCTN47196031), we randomized 26 high

165 These data demonstrate how registry-based randomized trials may offer methods for enrollment feedb

166 We review, in addition to the group-randomized trial, methods for two closely related design

167 of 3511 patients from the PARTNER 2 Cohort A randomized trial (n=1910) and SAPIEN 3 registry (n=1601)

168 of this strategy in a stepped-wedge cluster randomized trial (NCT01960972).

169 In a randomized trial of 103 patients with COVID-19, convales

170 ASPREE was a randomized trial of 19,114 community-dwelling persons in

171 : Double-blind, placebo-controlled, parallel randomized trial of 342 patients with IPF, breathlessnes

172 is a multicenter, open-label, 2x2 factorial, randomized trial of 447 patients with aortic stenosis un

173 We performed a single-center, randomized trial of 66 patients with confirmed or suspec

174 Data came from a randomized trial of a cash transfer conditional on schoo

175 Data came from a randomized trial of a cash transfer conditional on schoo

176 y-2 factorial design, we conducted a cluster-randomized trial of a home-based CHW intervention in 2 o

177 We report a randomized trial of a research ethics training intervent

178 wledge, this was the first large, long-term, randomized trial of an intervention directed at improvin

179 We performed a randomized trial of clopidogrel in patients undergoing T

180 lysis to compare the predicted outcomes of a randomized trial of EBRT plus ADT versus EBRT plus BT.

181 nhibition in Subjects with Elevated Risk), a randomized trial of evolocumab versus placebo in patient

182 timmunization from 60 patients enrolled in a randomized trial of HD versus SD vaccine (30 HD; 30 SD)

183 A randomized trial of hydroxychloroquine as postexposure p

184 (Randomized Trial of IN.PACT Admiral(R) Drug Coated Ballo

185 n (5-17 years old) were enrolled in a 1-year randomized trial of integrated pest management plus educ

186 In this randomized trial of laparoscopic and open liver surgery,

187 In a randomized trial of patients undergoing EUS-FNA for panc

188 ral selective Janus kinase 1 inhibitor, in a randomized trial of patients with Crohn's disease (CD).

189 In a randomized trial of patients with IBS, we found that nei

190 In a randomized trial of patients with NAFLD, 1 year of admin

191 In this subanalysis of a randomized trial of patients with polycystic liver disea

192 In a randomized trial of patients with refractory GERD, addin

193 In a randomized trial of patients with treatment-refractory I

194 In older patients with SCA, a randomized trial of postoperative chemotherapy compared

195 We conducted a phase II randomized trial of romiplostim versus untreated observa

196 both the WGHS and in JUPITER (N = 8,749), a randomized trial of rosuvastatin for primary prevention

197 A prospective, randomized trial of systemic corticosteroid use in endop

198 We performed a cluster randomized trial of TB screening among adults newly diag

199 We performed a phase 2b, randomized trial of the safety and efficacy of GR-MD-02

200 (Prospective, Randomized Trial of Ticagrelor Versus Prasugrel in Patie

201 In A Randomized trial of Unruptured Brain Arteriovenous malfo

202 ine candidates are available, but conducting randomized trials of additional candidates in outbreaks

203 he systematic review identified 114 eligible randomized trials of antibiotic prophylaxis.

204 220 patients with parenchymal NCC from three randomized trials of antiparasitic treatment was assesse

205 ening instruments; and systematic reviews of randomized trials of behavioral and pharmacologic treatm

206 Randomized trials of BP pharmacologic treatment (more in

207 PATIENTS: Secondary analysis of multicenter randomized trials of critically ill adults in which mort

208 Randomized trials of drug-eluting stents (DES) and drug-

209 ed Trials, MEDLINE, and Embase databases for randomized trials of eHealth interventions in solid orga

210 Randomized trials of masks and risk for respiratory viru

211 m the selection of targets and the design of randomized trials of novel therapeutics.

212 In 2 randomized trials of patients with iron-deficiency anemi

213 Individual patient-data were pooled from 10 randomized trials of patients with STEMI undergoing prim

214 We systematically identified all randomized trials of PCI on a background of medical ther

215 ese points with evidence from two studies of randomized trials of PES programs aimed at increasing fo

216 ibility of potential individual- and cluster-randomized trials of sodium reduction on cardiovascular

217 ther research into underlying mechanisms and randomized trials of supplementation.

218 Recently reported, positive randomized trials of the drugs gilteritinib, quizartinib

219 Randomized trials of therapies that primarily lowered tr

220 The randomized trials of ticagrelor captured adverse events,

221 This is the first prospective randomized trial on the influence of initial prescriptio

222 SCOPE 2 was a randomized trial performed at 23 centers in 6 countries

223 farction) was a prospective, open, parallel, randomized trial performed at 26 centers.

224 ences in overall survival have been found in randomized trials performed in the general breast cancer

225 Four registered randomized trials plan to evaluate ACEIs and ARBs for tr

226 atrial fibrillation has been evaluated in 2 randomized trials; post-approval clinical data are limit

227 However, further randomized trials powered to address potential sex-speci

228 In this long-term follow-up study of 2 randomized trials, prior randomized use of CEE alone, co

229 Two randomized trials published in 2019 to assess TAVI in pa

230 follow-up analysis of a previously-published randomized trial (RCT) evaluating the 2-years effects of

231 There are limited data from randomized trials regarding whether volume-based, low-do

232 In this adequately powered randomized trial, repair of mitral prolapse with either

233 This randomized trial report is based on a post hoc analysis

234 Three single-center randomized trials reported no significantly different or

235 This long-term follow-up of a randomized trial reporting no apparent effect of high-do

236 nti-PD-L1 monoclonal antibody) from multiple randomized trials representing 1,445 patients with metas

237 We extended the community-randomized trial results about vaccination strategy with

238 Randomized trials should be performed to confirm these r

239 In a phase 2 multicenter open-label randomized trial sponsored by the National Institutes of

240 These data strongly support the need for a randomized trial sufficiently powered to compare the lat

241 The results from this randomized trial suggest that SMILE produced promising r

242 , mechanistic insights and observations from randomized trials suggest no clear benefit on HF-related

243 We conducted a randomized trial that assessed the efficacy of single-ag

244 PALLET is a phase II randomized trial that evaluated the effects of combinati

245 Data on major amputation from a large randomized trial that included a substantial cohort of p

246 In a 2010 randomized trial (the PANTER trial), a surgical step-up

247 n the United Kingdom, we conducted a cluster randomized trial, the Primary-Secondary Care Partnership

248 Post hoc analysis within a randomized trial, the Starting Antiretroviral Therapy at

249 Among the 16 randomized trials, the most promising results showed imp

250 In a multicenter randomized trial, thermal ablation of the post-EMR mucos

251 ion Effectiveness Trial (ResPECT), a cluster randomized trial to assess personal protective equipment

252 We performed a multicenter, randomized trial to assess the safety and efficacy of a

253 We conducted a parallel, nonblinded randomized trial to assess whether offering home pregnan

254 In a randomized trial to compare 2 commonly used electrosurgi

255 We conducted a randomized trial to compare physical therapy with glucoc

256 mph node retrieval strengthen the need for a randomized trial to confirm the oncological safety of MI

257 We conducted a pragmatic, cluster-randomized trial to determine whether contact evaluation

258 We performed a single-blinded, randomized trial to determine whether type of electrosur

259 igned this double-blind, placebo-controlled, randomized trial to determine, in patients with COPD who

260 We conducted a randomized trial to evaluate GO in combination with inte

261 We conducted a pragmatic, cluster-randomized trial to evaluate the effectiveness of a mult

262 We performed a randomized trial to evaluate the efficacy of complete cl

263 red multiple treatment arms from a community-randomized trial to evaluate whether increasing frequenc

264 This is the first international randomized trial to our knowledge conducted in chemother

265 potential risk factors among a subset of the Randomized Trial to Prevent Vascular Events in HIV (REPR

266 The Randomized Trial to Prevent Vascular Events in HIV (REPR

267 The REPRIEVE trial (Randomized Trial to Prevent Vascular Events in HIV) enro

268 ed baseline kidney function in the REPRIEVE (Randomized Trial to Prevent Vascular Events in HIV) tria

269 rin inhibitors avoidancE trial was the first randomized trial to study early withdrawal of CNIs in de

270 We conducted a cluster-randomized trial to test the effectiveness of a high-int

271 We conducted an open-label, randomized trial to test whether a moxifloxacin-containi

272 icoagulation enrolled in the Evolut Low Risk randomized trial underwent computed tomographic imaging

273 These data need to be confirmed in randomized trials using new-generation TAVR devices.

274 We estimated transition probabilities from randomized trials using parametric survival modeling.

275 A stepped-wedge, cluster-randomized trial was conducted in 11 hospitals recruited

276 A prospective, open, randomized trial was conducted in nonpregnant, consentin

277 The randomized trial was fielded in active faculty-led labor

278 N, SETTING, AND PARTICIPANTS: This clustered randomized trial was implemented at 160 worksites from J

279 ulticenter, pragmatic, stepped-wedge cluster randomized trial was performed in five UK hospitals, inv

280 The aim of this randomized trial was to evaluate the efficacy and safety

281 In this multicenter, randomized trial, we assigned patients with ARDS to rece

282 In this double-blind, randomized trial, we assigned patients with type 2 diabe

283 In this randomized trial, we compared rivaroxaban (20 mg once da

284 In this prospective, single-blinded, 1:1 randomized trial, we enrolled 330 participants at 29 int

285 In a phase 2 randomized trial, we found that addition of NAPs to TDF

286 In a randomized trial, we found that endoscopic clip closure

287 In a multicenter, randomized trial, we found that including CADe in real-t

288 Using a parallel-group randomized trial, we randomly allocated 174 postmenopaus

289 In a substudy of a large randomized trial, we randomly assigned patients who had

290 In this double-blind, randomized trial, we recruited 88 hospitalized patients

291 review, one meta-analysis, and 34 additional randomized trials were identified.

292 ute Stroke Services) was a pragmatic cluster-randomized trial where the hospital was the unit of rand

293 Low risk of bias randomized trials which compared hypothermia applied for

294 An ongoing randomized trial will help confirm these hypothesis-gene

295 We conducted a randomized trial with 40 children aged 4-15 years at the

296 s a multicenter, open-label, non-inferiority randomized trial with a factorial design among treatment

297 PARTICIPANTS: FORWARD (FGF-18 Osteoarthritis Randomized Trial with Administration of Repeated Doses)

298 DESIGN, SETTING, AND PARTICIPANTS: Cluster randomized trial with enrollment from July 19, 2016, thr

299 OUT IX trial (Scandinavian Organization for Randomized Trials With Clinical Outcome IX), was a large

300 on of clinical efficacy would require larger randomized trials with more definitive outcome measures.