ライフサイエンスコーパス: raphe nuclei

1 pramammillary nucleus, lateral habenula, and raphe nuclei).

2 erences were found in cell counts within the raphe nuclei.

3 d on the ventrolateral medulla and medullary raphe nuclei.

4 by serotonin axons originating in the median raphe nuclei.

5 labeled neurons within the dorsal and median raphe nuclei.

6 itary tract (NTS), and the dorsal and median raphe nuclei.

7 ) receptor-immunoreactive cell bodies in the raphe nuclei.

8 ce of serotonergic innervation, the midbrain raphe nuclei.

9 , the periaqueductal gray, and/or the dorsal raphe nuclei.

10 ocaudal extent of rat serotonergic hindbrain raphe nuclei.

11 g the central gray and the dorsal and median raphe nuclei.

12 poglossal nucleus originates from the caudal raphe nuclei.

13 cleus, the ventral subiculum, and the median raphe nuclei.

14 L), receive serotonergic input from midbrain raphe nuclei.

15 in, thalamus, epithalamus, hypothalamus, and raphe nuclei.

16 present and arises from cells in the caudal raphe nuclei.

17 he periaqueductal gray and dorsal and median raphe nuclei.

18 certain Pet1/Fev neurons of the serotonergic raphe nuclei.

19 profiles, we examined the neurons within the raphe nuclei.

20 h their projections to the dorsal and median raphe nuclei.

21 rgic genes that are known to be expressed in raphe nuclei.

22 ing the neural circuitry between the LHb and raphe nuclei.

23 subpopulation of SERT-containing synapses in raphe nuclei.

24 tic acid (5-HIAA), and norepinephrine in the raphe nuclei.

25 roughout both cortical brain regions and the raphe nuclei.

26 mical modulation via the locus coeruleus and raphe nuclei.

27 laminergic VTA/SNc homologs and serotonergic raphe nuclei.

28 ls suggested this effect was mediated in the raphe nuclei.

29 ronal sections were cut through the midbrain raphe nuclei.

30 corpus C1, the reticular formation, and the Raphe nuclei.

31 g in known SERT-rich structures, such as the raphe nuclei.

32 aflet of the thalamus, and dorsal and median raphe nuclei.

33 ive strong serotonergic projections from the raphe nuclei.

34 de that (1) RTN receives input from multiple raphe nuclei, (2) serotonin, substance P, and TRH activa

35 ffected axon terminal field from the rostral raphe nuclei, (2) the degree of initial 5-HT axonal inju

36 d may antagonize self-inhibition of midbrain raphe nuclei 5-HT neurons.

37 In the raphe nuclei, 5-HT-immunoreactivity and 5-HT(5A)-immunor

38 ffinity dihydroergotamine receptors, and the raphe nuclei, a postulated brainstem site of action duri

39 Non-serotonergic neurons in the caudal raphe nuclei also project to the hypoglossal nucleus.

40 N include a serotonergic projection from the raphe nuclei and a neuropeptide Y (NPY) input from the i

41 within the dorsal, median, and caudal linear raphe nuclei and are suspected to inhibit AVP-facilitate

42 on after DD, including NA-LC, serotoninergic-raphe nuclei and dopaminergic-ventral tegmental area neu

43 es a dense serotonergic innervation from the raphe nuclei and expresses several serotonin (5-hydroxyt

44 MI) to quantify 5-HT(1A) binding in midbrain raphe nuclei and functional magnetic resonance imaging (

45 ing was evident in the pontine and medullary raphe nuclei and in sensory and spinal trigeminal nuclei

46 lar granule neurons, the locus ceruleus, and raphe nuclei and in various nuclei of the hypothalamus.

47 pathways originating from the medial/dorsal raphe nuclei and intergeniculate leaflet, or the brain's

48 anscripts expressed in neurons of the dorsal raphe nuclei and lateral hypothalamus that project to th

49 iac afferents reach subcortical serotonergic raphe nuclei and noradrenergic locus coeruleus (among ot

50 , locus coeruleus, pontine and caudal dorsal raphe nuclei and periaqueductal gray.

51 e (5-HT, serotonin), synthesized in midbrain raphe nuclei and released in various hypothalamic sites,

52 reas of the brainstem, the dorsal and median raphe nuclei and the locus coeruleus, were also investig

53 %) labeled for TPH2 in each of the medullary raphe nuclei and the medullary ventrolateral column were

54 te in the adult Pet-1(-/-) dorsal and median raphe nuclei and thus provided additional insight into F

55 mine was injected into the dorsal and median raphe nuclei and was visualized with Texas Red, while se

56 ontent, including the ventrolateral medulla, raphe nuclei, and area postrema, but were absent from al

57 ngulate cortex, nucleus accumbens, thalamus, raphe nuclei, and bed nucleus of the stria terminals.

58 lateral habenular nucleus, locus coeruleus, raphe nuclei, and cerebellar granule cells, intermediate

59 al area, substantia nigra, dorsal and median raphe nuclei, and cholinergic basal forebrain.

60 is bilaterally connected with serotoninergic raphe nuclei, and expresses high density of serotonin re

61 tegmental nucleus, in the linear and dorsal raphe nuclei, and in the substantia nigra.

62 the anterior nuclear group of the thalamus, raphe nuclei, and locus ceruleus.

63 thalamus, hypothalamus, periaqueductal gray, raphe nuclei, and locus coeruleus.

64 nuclei, hippocampus, medial thalamic groups, raphe nuclei, and many hypothalamic nuclei including the

65 ubstantia nigra, serotonergic input from the raphe nuclei, and noradrenergic input from the nucleus l

66 amygdala, ventral hippocampus, mesencephalic raphe nuclei, and novel localizations in the nucleus of

67 medullary reticular formation, the medullary raphe nuclei, and nucleus retroambiguus (the expiration

68 ular nuclei, the ventral medial medulla, the raphe nuclei, and parapyramidal areas.

69 in the the serotoninergic dorsal and median raphe nuclei, and the core of the noradrenergic locus co

70 rea, the rhabdoid nucleus, the mesencephalic raphe nuclei, and the dorsal tegmental nucleus.

71 and lateral pontine reticular formation, the raphe nuclei, and the locus coeruleus.

72 gic neurons in the tuberomammillary nucleus, raphe nuclei, and ventrolateral medulla, as well as a fe

73 zoid nucleus (RTN), in the medullary midline raphe nuclei, and, more dorsally in the medulla, in the

74 circadian timekeeping system, and within the raphe nuclei, appear to be present on serotonin neurons.

75 We conclude that the raphe nuclei are affected in a subgroup of early drug-na

76 Serotonergic (5-HT) axons from the raphe nuclei are among the earliest afferents to innerva

77 The serotonergic raphe nuclei are involved in regulating brain states ove

78 Serotonergic neurons in the raphe nuclei associated with stress and fear project to

79 Pet-1 and 5-HTT mRNA levels in the midbrain raphe nuclei at a time when the anorexigenic effect of e

80 h tryptophan hydroxylase-positive neurons in raphe nuclei but not with their nonserotonergic neuron o

81 eriaqueductal grey and the dorsal and linear raphe nuclei, but no double labeled cells were seen in t

82 mpus, subiculum, locus coeruleus, and dorsal raphe nuclei, but not inferotemporal cortex or cerebellu

83 te that action potentials conducted from the raphe nuclei can release 5-HT throughout the NAc, wherea

84 the ventral (p<0.0001) and dorsal (p=0.0002) raphe nuclei, caudate (p=0.00015), putamen (p=0.036), th

85 in transporter availability in the brainstem raphe nuclei compared to controls (P < 0.01) and subject

86 rved at any level of the locus coeruleus, or raphe nuclei, comparing subjects with major depression t

87 The medullary raphe nuclei contain putative central respiratory chemor

88 .62 +/- 0.07; ADs 1.18 +/- 0.26) and also in raphe nuclei (controls 0.63 +/- 0.09; ADs 0.37 +/- 0.20)

89 Serotonergic neurons in the brainstem raphe nuclei densely innervate the olfactory bulb (OB),

90 Serotonin neurons in the dorsal and median raphe nuclei (DR and MR) are clustered into heterogeneou

91 to the serotonergic median (MnR) and dorsal raphe nuclei (DR).

92 quantified throughout the dorsal and median raphe nuclei (DRN and MRN) by conducting in situ hybridi

93 ectrical stimulation of the dorsal or median raphe nuclei (DRN and MRN, respectively) induced 5-HT re

94 vely from serotonergic neurons in the dorsal raphe nuclei (DRN) augments aggressive behavior in male

95 re, we reveal that 5HT neurons in the dorsal raphe nuclei (DRN) send projections to the fastigial dee

96 found that neurotoxic lesions of the dorsal raphe nuclei (DRN) significantly decreased HAL-induced V

97 used to elevate RGS4 mRNA in the rat dorsal raphe nuclei (DRN) while extracellular levels of 5-HT in

98 neurons preferentially project to the dorsal Raphe nuclei (DRN).

99 a) in serotonin (5-HT) neurons in the dorsal raphe nuclei (DRN).

100 fatin-1 immunoreactivity was detected in the raphe nuclei, Edinger-Westphal nucleus, locus coeruleus

101 T), either systemically or into the midbrain raphe nuclei, elicit food intake in otherwise satiated r

102 vivo, stimulation of brainstem serotonergic raphe nuclei evokes whisker movements.

103 C regions (F1,88 = 5.19; P = .03) and in the raphe nuclei (F1,87 = 7.38; P = .008; R2 = 0.12).

104 FC regions (F1,88 = 0.03; P = .87) or in the raphe nuclei (F1,88 = 0.29; P = .59).

105 positive neurons were present in the midline raphe nuclei, formed a column in the ventrolateral medul

106 lore the role of GABAergic modulation in the raphe nuclei, from which most 5-HT in the forebrain orig

107 ut, the serotonin (5-HT) projection from the raphe nuclei, has been extensively investigated in rats

108 (5-HTP) in tissue from the dorsal and median raphe nuclei, hippocampus, cortex, caudate nucleus, and

109 onergic neurons would be found in the dorsal raphe nuclei in depressed elderly subjects, compared wit

110 the level of involvement of the serotonergic raphe nuclei in early Parkinson's disease is still debat

111 etermine: (i) the integrity of the brainstem raphe nuclei in early Parkinson's disease; and (ii) whet

112 te reticular formation with its serotonergic raphe nuclei in facilitating locomotion, postural moveme

113 urons or of neuritic pathology in the dorsal raphe nuclei in older people with depression, with or wi

114 TPH-IR) in the dorsal (DRN) and median (MRN) raphe nuclei in suicides and controls.

115 However, the role of these three raphe nuclei in the acupuncture responses is unknown.

116 In mammals, 5-HT release from the raphe nuclei in the brainstem can modulate the functiona

117 ey role for microRNA-135a [corrected] in the raphe nuclei in the molecular mechanisms underlying the

118 eniculate leaflet, and the median and dorsal raphe nuclei), in the Syrian hamster.

119 Therefore, the raphe nuclei, in addition to their role in neuromodulati

120 formation as well as the spinally projecting raphe nuclei increased their projections to the cortical

121 ed in Pet-1(+/-) and Pet-1(-/-) adult dorsal raphe nuclei, indicating that the majority of mutant ser

122 sent study evaluated c-Fos activation in the raphe nuclei induced by EA and examined its relationship

123 retrorubral field, rostral and caudal linear raphe nuclei, interfascicular nucleus, and supramammilla

124 mosensory behaviours driven by the brainstem raphe nuclei into these parallel systems.

125 Elevated 5-HT1A binding in raphe nuclei is associated with subsequent remission wit

126 system, which originates from the brainstem raphe nuclei, is disrupted in Parkinson's disease.

127 n the hippocampus and cortex, but not in the raphe nuclei, is sufficient to rescue the behavioural ph

128 NTS, area postrema, VRC, dorsolateral pons, raphe nuclei, lateral hypothalamus, central amygdala, an

129 zona incerta, thalamus, periaqueductal gray, raphe nuclei, lateral parabrachial nucleus, locus coerul

130 following brainstem/forebrain sites: caudal raphe nuclei, laterodorsal tegmental nucleus, dorsal rap

131 Brief stimulation of the raphe nuclei led to excitation of tufted cells at rest a

132 aused neuronal loss in the substantia nigra, raphe nuclei, locus coeruleus, nucleus basalis of Meyner

133 significant effect of MAO-A genotype in the raphe nuclei, medial and inferior temporal cortex, insul

134 Serotonin (5-HT) neurons located in the raphe nuclei modulate a wide range of behaviors by means

135 sms through which 5-HT neurons in the dorsal raphe nuclei modulate amygdala circuits.

136 CRFR2 in the midbrain raphe nuclei modulate serotonergic activity of this key

137 The dorsal (DRN) and median raphe nuclei (MRN) are two major sources of serotonergic

138 vely few PVH-projecting neurons in ascending raphe nuclei, nucleus of the solitary tract, or ventrola

139 aining the opioid and 5-HT were found in the raphe nuclei of all animals following application of col

140 hology in serotonergic neurons in the dorsal raphe nuclei of elderly subjects with primary major depr

141 Serotonin(1A )BPF in the raphe nuclei of suicide attempters was positively correl

142 rogeneity in populations of the serotonergic raphe nuclei of the brainstem reticular formation, with

143 lei, nucleus incertus, and dorsal and median raphe nuclei of the brainstem.

144 MN deficiency in serotonergic neurons in the raphe nuclei of the brainstem.

145 malian spinal cord, originates mainly in the raphe nuclei of the brainstem.

146 e of dopamine (DA) in the frontal cortex and raphe nuclei of the freely moving rat was measured using

147 the locus coeruleus as well as in the dorsal raphe nuclei of the human.

148 The serotonergic raphe nuclei of the midbrain are principal centers from

149 tor heterocomplexes in the dorsal and median raphe nuclei of the Sprague Dawley rat as well as in the

150 PHA-L was also placed into the dorsal raphe nuclei or nucleus of Darkschewitsch and interstiti

151 prelimbic PFC that may arise from different raphe nuclei or that represent varicose and intervaricos

152 tal gray matter, dorsal and central superior raphe nuclei, parabrachial nucleus, pre-locus coeruleus

153 ular nuclei; substantia nigra, central gray; raphe nuclei; parabrachial nuclei; locus ceruleus, nucle

154 tic labeling was identified in the medullary raphe nuclei, parapyramidal region, A5, Barrington's nuc

155 These results suggest that the medullary raphe nuclei, particularly the NRP, process somatic sign

156 ic nuclei, the reticular formation, midbrain raphe nuclei, periaqueductal gray and parabrachial nucle

157 ental area, oculomotor nucleus, red nucleus, raphe nuclei, periaqueductal gray, locus coeruleus, trig

158 ncluding basal ganglia, locus coeruleus, and raphe nuclei (phase II), followed by primary motor corte

159 Midbrain raphe nuclei provide a diffuse projection to all regions

160 The raphe nuclei provide serotonergic innervation widely in

161 The dorsal raphe nuclei receive light input from the circadian visu

162 n the striatum, its binding in the brainstem raphe nuclei reflects serotonin transporter availability

163 e of PR-ir cells colocalizing TPH-ir in both raphe nuclei, regardless of sex and genotype.

164 TP influx rate was observed in the amygdala, raphe nuclei region, caudate nucleus, putamen, hippocamp

165 elevated [11C]DASB binding potential in the raphe nuclei region, caudate nucleus, putamen, thalamus,

166 Serotonin 1A (5HT(1A)) autoreceptors in the raphe nuclei regulate adult stress vulnerability, but wh

167 ervation from the dorsal and median midbrain raphe nuclei, respectively.

168 er the hippocampal formation or the midbrain raphe nuclei resulted in retrograde labeling of many cel

169 , various tegmental nuclei, locus coeruleus, raphe nuclei, reticular nuclei, and the nuclei of the tr

170 higher serotonin1A binding potential in the raphe nuclei (RN) is associated with greater lethality o

171 g neurons control sleep via the serotonergic raphe nuclei (RN), a hindbrain structure that is critica

172 At day 31, their raphe nuclei (RN), amygdala (AMY), frontal cortex (FC),

173 The serotonergic raphe nuclei (RNi) connections involve regions of the SM

174 oeruleus (LC) neurons and serotonergic (5HT) raphe nuclei (RNs) in the hindbrain express distinct pth

175 Raphe nuclei serotonin(1A) BPF was 45.1% greater in high

176 urons), rostral ventromedial medulla, caudal raphe nuclei (serotonin neurons in the raphe pallidus an

177 vision are known to be the dorsal and median raphe nuclei, sources of serotonin located within other

178 ptor sub-type at different locations (brain, raphe nuclei, spinal cord and autonomic ganglia) may mod

179 Consistent SERT pathology in raphe nuclei, striatum, thalamus, and hypothalamus and a

180 (5-HT)-immunoreactive neurons of the caudal raphe nuclei, substance P (SP)-immunoreactive neurons of

181 ially innervate the interpeduncular nucleus, raphe nuclei, substantia nigra pars compacta and ventral

182 serotonergic projections from the medullary raphe nuclei, suggesting that 5-HT modulates vagal activ

183 eral nuclei, but not with locus coeruleus or raphe nuclei support the view that these peptides origin

184 dbrain but higher uptake in the thalamus and raphe nuclei than control patients.

185 ad 33% higher baseline 5-HT1A binding in the raphe nuclei than nonremitters (p = .047).

186 l molecular and neurochemical changes in the raphe nuclei that dysregulate 5-HT neuronal activity and

187 enkephalin-containing neurons in the caudal raphe nuclei that projected to the hypoglossal nucleus a

188 samples that contained the dorsal and median raphe nuclei (the location of serotonin cell bodies that

189 Among the brainstem raphe nuclei, the dorsal raphe nucleus (DR) contains the

190 ental area, the interpeduncular nucleus, the raphe nuclei, the dorsal tegmental nucleus, and the nucl

191 , the medial reticular formation nuclei, the raphe nuclei, the glossopharyngeal nuclei, and the Purki

192 the central gray, the substantia nigra, the raphe nuclei, the parabrachial area, the medullary retic

193 c periaqueductal grey, the dorsal and linear raphe nuclei, the parabrachial nucleus, and the dorsal v

194 binding for each marker was observed in the raphe nuclei, the site of the highest density of 5-HT ce

195 the inferior olivary nucleus, the medullary raphe nuclei, the spinal and principal trigeminal nuclei

196 ulate 5-HT neuronal activity in the midbrain raphe nuclei through alpha-amino-3-hydroxy-5-methyl-4-is

197 Serotonin (5-HT) neurons project from the raphe nuclei throughout the brain where they act to main

198 The two raphe nuclei thus give dual innervation within the OB, w

199 pallidus, and the rostral and caudal linear raphe nuclei to subsets of midline and intralaminar thal

200 find that serotonergic projections from the raphe nuclei to the olfactory bulb dramatically enhance

201 and several brainstem cell groups: medullary raphe nuclei, ventromedial medulla (VMM), rostral ventro

202 oss of 5-HT nerve cell bodies in the rostral raphe nuclei was found, indicating that abnormal innerva

203 Innervation of raphe nuclei was most dense at the level of RVLM, but ro

204 and the serotonergic cell groups, the dorsal raphe nuclei, was measured autoradiographically in postm

205 s in the SLN, PMRF, dorsal raphe, and median raphe nuclei were 4,571, 1,948, 15,191, and 4,114, respe

206 Many non-serotoninergic neurons in the raphe nuclei were also infected with rabies virus, indic

207 Tryptophan hydroxylase protein levels in the raphe nuclei were not significantly different between co

208 inding densities of [3H]nisoxetine in dorsal raphe nuclei were similar to that in the locus coeruleus

209 repositus hypoglossi, vestibular nuclei, and raphe nuclei, were infected by transynaptic passage of P

210 ibers originating from the dorsal and median raphe nuclei while fluorescence immunohistochemistry was

211 f 5-HTT mRNA were detected in all brain stem raphe nuclei, with variations in labeling among the vari

212 tegy to manipulate 5-HT(1A) autoreceptors in raphe nuclei without affecting 5-HT(1A) heteroreceptors,