ライフサイエンスコーパス: rapid

1 ure positivity; however, this was not always rapid.

2 ofunctionalized byproducts, thereby offering rapid access to these privileged scaffolds with high che

3 rge scale population studies that provides a rapid, accurate and reproducible alternative to labor in

4 ficient excision is limited by the lack of a rapid, accurate measurement of DNA excision outcomes tha

5 , we present a machine learning pipeline for rapid, accurate, and sensitive assessment of the endocri

6 ty of NMDARs, which are the targets of novel rapid-acting antidepressants.

7 In addition, the antidepressant effects of rapid-acting drugs are thought to occur via inhibition o

8 hours of a pulse disturbance, demonstrating rapid adaptation by specific populations.

9 onstrate metabolic coupling in a remarkable, rapid adaptation process (1 in 1,000 cells adapt per hou

10 lso accelerating genetic diversification and rapid adaptation.

11 erves as a fundamental mechanism that drives rapid adaptive evolution in human populations.

12 the advent of effective therapy have led to rapid adoption of diagnostic scintigraphy, there is hete

13 The rapid adoption of LEPA technologies did not slow pumping

14 f large-scale science-related challenges and rapid advancements in groundbreaking science with major

15 Rapid advances in cellular engineering(1,2) have positio

16 mM1000, with the latter appearing capable of rapid aggregation, albeit initially forming smaller, wea

17 ed quickly with high reliability and exhibit rapid, aggressive infiltration when transplanted into ad

18 Rapid and accurate diagnostic tools are needed for appro

19 d a tetrazine (Tz)-based radioligand via the rapid and bioorthogonal inverse electron-demand Diels-Al

20 nostic tests play a crucial role in enabling rapid and correct diagnosis of diseases in prehospital c

21 This methodology can be used for rapid and cost-effective measurements of emerging materi

22 A rapid and early diagnostic test to identify the encephal

23 This rapid and extensive dark oxidation elevates the importan

24 Our results demonstrate that rapid and extensive transcription reprogramming associat

25 a large mutant resource for S. viridis in a rapid and high throughput manner, and has the potential

26 The assay allowed a rapid and high-sensitive C. acutatum detection mean, bei

27 The optimized CBS workflow allows for rapid and high-throughput screening and quantitation of

28 Here, we achieved rapid and homogeneous electrochemical detection by fabri

29 These rapid and living practice points from the American Colle

30 Our analysis approaches provide rapid and modular approaches to screen for alterations i

31 Here, we present a highly sensitive, rapid and multiplexed protocol termed UbiFast for quanti

32 Thioflavin T fluorimetry estimates rapid and near-stoichiometric coassembly of CATCH(+) and

33 clinicians and scientists with an accurate, rapid and objective technique for quantification of lens

34 Our study demonstrates the rapid and portable detection of the two most relevant ge

35 Development of a rapid and portable platform for detecting and monitoring

36 Innate immune responses rely on rapid and precise gene regulation mediated by accessibil

37 Rapid and precise identification of cases and tracing of

38 A rapid and reliable method for the differentiation betwee

39 We identified rapid and repeated loss of olfactory capacities synchron

40 We established rapid and reversible optogenetic control for Set2, the s

41 is mostly image based and therefore requires rapid and robust extraction of phenotypic measurements f

42 We developed a rapid and robust separation protocol for trace silver ex

43 ard culture conditions are associated with a rapid and selective loss of BBB transcripts and chromati

44 omposite system as a biosensing test-bed for rapid and sensitive detection of dopamine (DA).

45 anomaterials offers a viable alternative for rapid and sensitive determination of these non-PSA marke

46 In this study, we developed a rapid and simple capillary electrophoresis-ultraviolet a

47 The developed test strip shows promise as a rapid and simple POC quantitative acetaminophen assay.

48 d to mass spectrometry (SLIM IMS-MS) for the rapid and simultaneous characterization of the drug load

49 -specific nanobodies, this method will allow rapid and specific degradation of a wide range of endoge

50 GB001 may have a rapid and sustained effect on lung function, particularl

51 RUX cream provided rapid and sustained improvements in AD symptoms and was

52 effective treatment is expected to achieve a rapid and sustained response, the response at a fixed ti

53 Rather, translocation is rapid and thermodynamically favorable after enzyme openi

54 .03 $ per sweat patch), portable, selective, rapid, and non-invasive healthcare monitoring device for

55 fluidic device that was capable of executing rapid antimicrobial susceptibility tests with one, two,

56 A sensitive and rapid assay for distinguishing positive from negative de

57 naxNOW TM and RT-PCR in a community setting, rapid assay sensitivity was 100%/98.5%/89% using RT-PCR

58 hly novel gene therapy approach in a canine, rapid atrial pacing model of AF, we demonstrate that NAD

59 still allow effective treatment of patients, rapid, automated, and reliable antibiotic susceptibility

60 ous anatomic compartments obtained through a rapid autopsy program of individuals undergoing long-ter

61 od samples before death and their bodies for rapid autopsy.

62 rizontally transmit genetic traits, enabling rapid bacterial adaptation to new environments and hosts

63 kill assay revealed that auranofin exhibited rapid bactericidal activity against N. gonorrhoeae.

64 igallocatechin gallate (ECGC) exhibited very rapid binding (in the order of seconds) with Human Saliv

65 ficient structural definition to support the rapid binding of a heme cofactor.

66 otentially noninvasive, high-resolution, and rapid biological imaging materials.

67 Glucocorticoids induced rapid bone marrow homing of eosinophils.

68 The pace of knowledge acquisition has been rapid, but ongoing challenges include accurately diagnos

69 The method involves the rapid capture of multiple visible and near-infrared imag

70 nhancers with specific binding sites promote rapid Cdk8-dependent Notch turnover, and thereby reduce

71 modulating the developmental transition from rapid cell elongation to secondary cell wall synthesis.

72 the Drosophila germband predict the onset of rapid cell rearrangement in both wild-type and snail twi

73 tumor glioblastoma (GBM) is characterized by rapid cellular infiltration of brain tissue, raising the

74 ticipation is maintained throughout times of rapid change to adapt while supporting essential structu

75 arance of hepatitis C virus (HCV) results in rapid changes in metabolic parameters early in direct-ac

76 Reducing unnecessary biopsies and rapid characterization of breast microcalcifications are

77 sides the development of new drugs, requires rapid, cheap, scalable, and accurate diagnostics.

78 To support rapid chemical toxicity assessment and mechanistic hypot

79 However, the rapid clearance of Sunb-malate eye drops administered th

80 Rapid climate change has wide-ranging implications for t

81 Four key features of DVME that allow for the rapid collection of vapor samples under thermodynamic co

82 , where efforts may necessitate establishing rapid conservation interventions postconflict that align

83 sis of useful alpha-chiral alkyl amines, and rapid construction of different ureas and primary amines

84 animal communication have documented myriad rapid, context-dependent changes in visual and acoustic

85 quency alternating current (KHFAC) generates rapid, controlled, and reversible conduction block in mo

86 In the present study, the effect of rapid cooling on the silicon particle size, distribution

87 This work presents for the first time a rapid creation of 3D scaffolds using magnetic levitation

88 rical simulations indicate that the observed rapid cross-frontal mixing occurs via shear dispersion,

89 In the presence of rapid cultural, environmental, or genetic change, the re

90 s was acquired early during the evolution of rapid cycling trait in rice subspecies.

91 The rapid, data-driven evolution of these procedures is uniq

92 ation of bacteria throughout the organs, and rapid death.

93 Following the rapid decay (0.6 ns) of a small spectral side band, the

94 cts from this facility was associated with a rapid decline in the incidence of L. monocytogenes ST6 i

95 le duplication defects, in part by causing a rapid decline in the level of TUBGCP6.

96 Global biodiversity is undergoing rapid declines, driven in large part by changes to land

97 ransfer insulator YBa(2)Cu(3)O(6.1) revealed rapid demagnetization within 90 fs of photoexcitation.

98 ve a high peak incidence consistent with the rapid depletion of susceptible individuals.

99 Rapid detection of Acinetobacter baumannii (AB) is criti

100 and researchers are developing tests for the rapid detection of individuals who may carry the severe

101 e developed the first biosensor platform for rapid detection of otolin-1 and prestin, blood-circulati

102 discovery offer promising potential for the rapid development of novel polymer systems.

103 ceuticals with antitumour effects, have seen rapid development over the past decade.

104 Improved rapid diagnosis and antimicrobial resistance determinati

105 y fluids has become the preferred method for rapid diagnosis of many infectious diseases.

106 T2) study, a randomized, controlled trial of rapid diagnostic genomic sequencing of infants in region

107 ification (LAMP) was compared to traditional rapid diagnostic testing (RDT) for the improved detectio

108 Tp with SP against intermittent screening by rapid diagnostic tests (ISTp).

109 proper guidelines and algorithms, available rapid diagnostic tests (RDTs) for common acute undiffere

110 consider incorporating dual HIV and syphilis rapid diagnostic tests as the first test in antenatal ca

111 Incorporating dual rapid diagnostic tests in antenatal care can be cost-sav

112 g evaluated for tuberculosis (TB), a lack of rapid diagnostic tests which can fully describe TB resis

113 luate a new diagnostic test developed in the Rapid Diagnostics in Categorizing Acute Lung Infections

114 sing clinical awareness and access to simple rapid diagnostics may improve the diagnosis of blastomyc

115 portunities and challenges for integrating a rapid diet screener tool into clinician workflows throug

116 the theory- and practice-based criteria of a rapid diet screener tool that supports valid and feasibl

117 ide rationale for the widespread adoption of rapid diet screener tools in primary care and relevant s

118 and federal levels, as well as the need for rapid dissemination of clinical information related to t

119 s, providing a modular disconnection for the rapid diversification of heteroaromatic cores.

120 Heme, in a dose-dependent manner, induced a rapid drop in the endothelial barrier integrity of HLMVE

121 esenting cell form an immunological synapse, rapid dynein-driven translocation of the centrosome towa

122 at electronic-vibrational mixing facilitates rapid EET over moderately size energy gaps.

123 redox-active ligands work together to enable rapid electrochemical CO(2) reduction at moderate overpo

124 tors (SSRIs), initiate their drug actions by rapid elevation of serotonin, but they take several week

125 that termination is completely abolished by rapid elimination of CPSF73, which causes very extensive

126 eriods of stable viral loads are followed by rapid elimination, which could be coupled with cytokine

127 on of resistant strains, thus leading to the rapid emergence and subsequent spread of resistance.

128 ts that balance is increasingly urgent under rapid environmental change.

129 canonical gene regulation and can respond to rapid environmental changes.

130 that facilitates robust protein extraction, rapid enzymatic digestion (30 min compared to overnight)

131 ecificity, robustness, and clinical value of Rapid Estimation of Myelin for Diagnostic Imaging, a new

132 (SCPCompanion), a software tool that enables rapid evaluation of single-cell proteomic data and recom

133 te features of disturbances, species traits, rapid evolution and dispersal.

134 omy of cranial elements and facilitating the rapid evolution of regions that are remodelled through o

135 mammals, plants, and flies report pervasive rapid evolution of telomere proteins.

136 These findings support rapid evolvability of disomic strains that can be used t

137 nterconnections (plasmodesmata) facilitating rapid exchange of metabolites and signal molecules, plan

138 hange in clinical management after the ultra-rapid exome sequencing report, the time from hospital ad

139 ndividuals' ties undergo an initial cycle of rapid expansion and contraction.

140 hanisms could underlie this aneuploidy peak: rapid expansion of the engrafted HSPC population and bon

141 ntrained region in early visual areas in non-rapid eye movement (NREM) and REM sleep.

142 clear whether learning is facilitated by non-rapid eye movement (NREM) sleep or by REM sleep, whether

143 Notably, rapid eye movement (REM) sleep regulates emotional memor

144 Reward provided during training enhanced rapid eye movement (REM) sleep time, increased oscillato

145 During rapid eye movement (REM) sleep, behavioral unresponsiven

146 trocytes become less synchronized during non-rapid eye movement sleep after sleep deprivation at the

147 History can include prodromal features (eg, rapid eye movement sleep behavior disorder, hyposmia, co

148 The study demonstrates a novel, rapid, facile, and powerful approach for identification

149 s from very large blood volumes, followed by rapid flow, high-gradient magnetic sorting of untagged C

150 lpha-3 resulted in Arabidopsis plants with a rapid flowering phenotype similar to that of plants with

151 avior both on an acute timescale to adapt to rapid fluctuations in caloric intake and on a chronic ti

152 (PSII) model) incorporating parameters from rapid fluorescence response curves.

153 allow the standardisation of the cell-based rapid fluorescent-focus inhibition test (RFFIT) for rabi

154 ns of NBT plus beta- or alpha-NADPH elicited rapid formation of diformazan in the absence or presence

155 By monitoring the decay of Omega through rapid freeze-quench trapping at progressively longer tim

156 d the phosphorylation step, resulting in the rapid generation of the more active phosphorylated confo

157 We validate this technology with the rapid generation of three BCR KI lines expressing native

158 ression from promoter sequences would enable rapid generation of useful promoters and facilitate synt

159 In an era of rapid global change, our ability to understand and predi

160 The rapid global spread of COVID-19 represents perhaps the m

161 Tissue was stained with a modified rapid Golgi technique.

162 However, the rapid growth in complexity of data from these assays has

163 The rapid growth in U.S. unconventional oil and gas has made

164 Rapid growth of BAP1-deficient tumors indicates that the

165 All modern standards exhibit rapid growth releases every circa 30 years, most likely

166 renal and iliac arteries, and it can achieve rapid hemostasis in acutely injured vessels.

167 n-specialist veterinary clinicians to make a rapid herd level diagnosis and promptly implement approp

168 bacteria are inefficient, and often prevent rapid, high-throughput analyses.

169 ons in control over system properties (e.g., rapid hydrolysis or slow photolysis).

170 lear correlation NMR experiments allow for a rapid identification and differentiation of surface hydr

171 y/specificity of developed nanosystem toward rapid identification of ill people even at incubation an

172 observation suggests that HIV progress more rapid in females than males.

173 The rapid increase in antibiotic resistant pathogenic bacter

174 s an apparent coincidence between periods of rapid increase in refractive index in the lens nucleus a

175 The rapid increase of global temperatures highlights the nee

176 and chemokine gene promoters, facilitating a rapid inflammatory response to microbial pathogens.

177 ress a key drawback of Laurdan linked to its rapid internalization and subsequent labeling of interna

178 unctions indicating that Abeta(25-35) causes rapid internalization of Cx43 gap junctions.

179 r diffuse large B-cell lymphoma that require rapid interventions.

180 hem versus allowing clinicians some time for rapid investigation to minimize the risk of overtreatmen

181 their prey's response threshold until after rapid jaw expansion.

182 lications of pre-existing osteonecrosis, and rapid joint destruction (including bone loss) may be obs

183 ss spectrometry has the potential to provide rapid large-scale sample analysis at a speed of more tha

184 few colony-forming units, and infections are rapid, lasting roughly between 1 d and 3 d in the wild.

185 and their cognate pathogens often triggers a rapid localized cell death at the pathogen infection sit

186 It is thus a rapid, low cost portable test suitable for point-of-need

187 otagmin-1 by Ca(2+) is sufficient to trigger rapid (<100 msec) and synchronous fusion of the docked v

188 If repeated today, such rapid mass loss to the ocean would have clear implicatio

189 Here we report a versatile and rapid metallaphotoredox-catalysed method for late-stage

190 pectrometry (TIMS) is presented as a new and rapid method to distinguish between electrochemically ge

191 ecessary to ensure stability in transit, but rapid micellar breakdown and concomitant drug release, w

192 Dynamic phase separation enables rapid mobilization of this protein pool to protect expos

193 neutralization capacity within 12-15 days, a rapid, mostly transient upregulation of selective inflam

194 he results demonstrate that the capacity for rapid Na(+)-based signaling in eukaryotes is not restric

195 NIRS is a suitable, rapid, nondestructive method to determine isoflavone com

196 The method allows rapid, nontoxic measurement of the three-dimensional (3D

197 he subsequent dynamics is characterized by a rapid oblate-to-prolate shape transformation of the elec

198 period, July 2007-April 2013, a time of both rapid ocean warming throughout the Gulf of Maine and app

199 Treatment with NS9283 restores the rapid onset of the postsynaptic cholinergic response wit

200 The reaction is rapid, operationally simple, and chemoselective.

201 o regulate osteoclasts at the early stage of rapid palatal expansion and further facilitate bone form

202 pathogens can be attributed to the lack of a rapid pathogen identification (ID) or antimicrobial susc

203 cterial plasma membrane and thereby promotes rapid permeabilization of the plasma membrane and bacter

204 We therefore developed a platform for rapid phage display screening of deep recombinant librar

205 Rapid phenotypic AST for Ng is challenged by the pathoge

206 duals, random founder effects can facilitate rapid phenotypic divergence even in the absence of selec

207 R) signals induce Syk activation followed by rapid phosphatase-mediated desensitization; however, how

208 it, which likely promotes ATP hydrolysis and rapid phosphate release.

209 ) provided an ideal platform to achieve very rapid (picosecond time scale) and highly efficient energ

210 witch to glycolysis to allow them to perform rapid plastic responses.

211 ipants were randomly assigned to prospective rapid point-of-care genotyping of CYP2C19 major alleles

212 suspect screening workflow that allows for a rapid preannotation of HRMS data sets.

213 Given the rapid presentation rate and absence of explicit instruct

214 ctions with successive adjustments hindering rapid process intervention.

215 Equally rapid progress in mathematical oncology over this time p

216 resolution mass spectrometry has undergone a rapid progress in the last years due to instrumental imp

217 The rapid progress of MAS DNP has been largely enabled throu

218 ased (18)F-fluoride uptake demonstrated more rapid progression of calcification compared with those w

219 ment, but during the open-label period, more rapid progression was noted among patients in the placeb

220 The rapid proliferation of new synthetic cannabinoid recepto

221 CTAs) initiate polymerization and facilitate rapid proton transfer between active and dormant chains.

222 rganic materials is a versatile approach for rapid prototyping of various types of haptic devices.

223 hods, such as the end-user customization and rapid prototyping, useful in different application field

224 metamaterials remain hindered by the lack of rapid-prototyping ferroelectric metamaterial structures.

225 ism by which the innate immune system allows rapid quality check of absorbed fluids to avoid intoxica

226 More broadly, NucleaSeq enables rapid, quantitative and systematic comparisons of specif

227 e manufacturing (AM) are being reported at a rapid rate, the accountable thermokinetics of the entire

228 coral communities worldwide are declining at rapid rates.

229 RBCs leads to either abortive invasion with rapid RBC lysis, or successful entry but developmental a

230 ) and T(regs), subsequently followed by more rapid rebound of T(regs) Despite robust depletion of hos

231 GT3-Nano can facilitate rapid recovery of hematopoietic components in mice treat

232 follow-up; use of prescreening to facilitate rapid recruitment of participants; use of pre-randomizat

233 Time course analysis revealed rapid remodeling of diverse host systems, including sign

234 he ultrasmall size of Cu(5.4)O USNPs enables rapid renal clearance of the nanomaterial, guaranteeing

235 NA-responsive materials while enabling their rapid repurposing toward new sequence targets.

236 ted for greater competitive ability and more rapid resource utilization.

237 virus 2 (SARS-CoV-2) has elicited an equally rapid response aiming to develop a COVID-19 vaccine.

238 crucial state of this enzyme, allowing for a rapid response demanded by the biological function.

239 t lung eosinophilia that is initiated by the rapid response of bronchiolar club cells to Alp1.

240 These findings may inform rapid response strategies to optimize health care delive

241 y, low-cost production, high selectivity and rapid response, MIPs combined with miniaturized electroc

242 ned and executed an innovative, cooperative, rapid-response translational-research program that broug

243 d c-Myc and following BETi washout exhibited rapid restoration of c-Myc and JMJD6.

244 We observed a rapid, robust, and focused response to the EndoUmut viru

245 as magnetic stars(3), blue stragglers(4) and rapid rotators(5)), they play an important part in our i

246 Rapid SARS-CoV-2 countermeasure development is contingen

247 enultimate deglaciation can explain the more-rapid sea-level rise compared with the last deglaciation

248 atible ruthenium(II) vinyl probes allows the rapid, selective and sensitive detection of endogenous c

249 n the 3' UTR of the target gene, resulted in rapid self-cleavage and subsequent decay of the mRNA.

250 tion and its time-dependent progression, the rapid, sensitive, and noninvasive determination of immun

251 erall, our technology can greatly facilitate rapid, sensitive, and quantitative analysis of COVID-19

252 resent study, we report the development of a rapid, sensitive, robust, reliable, and highly specific

253 Rapid-set liquid bandages are efficient alternatives but

254 f both sexes in the new environment but also rapid sex-specific adaptation.

255 cfDNA, measured by a rapid simple assay, proved a valuable early marker of se

256 These nanocomposite sorbents exhibit rapid sorption with saturation occurring in less than 5

257 wareness of the need for early diagnosis and rapid specialist input from endocrinologists and ophthal

258 ease whereas the HSMRF-based model detects a rapid speciation-rate decrease in the last 12 million ye

259 However, the rapid spin relaxation observed in colloidal quantum dots

260 ins (both uncharacterized and known) using a rapid split fluorescent reporter characterization platfo

261 The rapid spread of COVID-19 has focused the efforts of scie

262 The rapid spread of severe acute respiratory syndrome corona

263 ed higher alpha-amylase activity, leading to rapid starch degradation and increase in soluble sugars,

264 iator-controlled Pol II kinetics by coupling rapid subunit degradation with orthogonal experimental r

265 noxide-releasing molecule 2 treatment caused rapid suppression of 2B6 enzyme activity, significant HM

266 A rapid Surface Enhanced Raman Spectroscopy (SERS) method

267 ssociated with indolent (TDT > 365 days) and rapid (TDT < 90 days) tumor growth.

268 POT1 alterations cause rapid telomere elongation, ATR kinase activation, telome

269 ly confined isthmus dimensions, confirmed by rapid termination of VT during radiofrequency delivery.

270 Galactomannan Lateral Flow Assay (LFA) is a rapid test for the diagnosis of invasive aspergillosis (

271 rmatory assay in 12.0% (10/83) and in an HIV rapid test in 31.3% (26/83).

272 s focus on pathogen identification that lack rapid testing of the patient immune response, impeding c

273 The availability of rapid tests to exclude bacteraemia may be of benefit in

274 to the strong requirement of zeaxanthin for rapid thermal dissipation and unsaturated fatty acids fo

275 0 vector into ZAP-70(-/-) mice resulted in a rapid thymocyte differentiation associated with the deve

276 new Corynebacterium RT-PCR method provides a rapid tool to screen isolates and identify probable diph

277 Our results thus demonstrate rapid trait refinement and adaptation to the new citrate

278 ion, however, was found to be dependent on a rapid transition to a cleaner grid.

279 As such, we favor rapid translation to human patients as an antiscarring t

280 n and evaluation of immunogenicity to enable rapid translation to the clinic.

281 port models remain unable to account for the rapid transport of sediment released from behind inciner

282 cted DAA therapy in Australia have permitted rapid treatment scale-up, with a dramatic reduction in H

283 Rapid trio genome sequencing in family 1 and exome seque

284 ided pharmacotherapy recommendations using a rapid turnaround test would change antiplatelet prescrib

285 Point-of-care (POC) testing with rapid turnaround times would allow more effective triage

286 nner' B cell clones at steady state, despite rapid turnover of germinal-centre B cells.

287 endogenous LAPTM4B-24 protein was subject to rapid turnover with a t(1/2) of approximately 1 hour.

288 They have rapid twitch kinetics (full width at half-maximal stress

289 architecture that is both robust, to enable rapid ubiquitylation of the substrate, and fragile, to e

290 e illumination were specifically impaired in rapid uncertainty-safety discrimination.

291 ile: the long noncoding RNA ephemeron, whose rapid upregulation is crucial for the transition of ESCs

292 dependence on this energy source, spurred by rapid urbanization and absence of viable cleaner alterna

293 JCI, Broger and Nicol et al. investigated 3 rapid urine tests in 372 ambulatory HIV-negative individ

294 rine diagnostics in Malawi and South Africa (Rapid urine-based Screening for Tuberculosis to reduce A

295 tic state, hemodynamic and hormonal changes, rapid uterine growth, changes associated with endothelia

296 al spike protein (S protein) associated with rapid virologic clearance.

297 t inducible deletion of adipose OGT causes a rapid visceral fat loss by specifically promoting lipoly

298 Detecting rapid visual field deterioration is crucial for individu

299 review, we address issues that relate to the rapid "Warp Speed" development of vaccines to counter th

300 This process causes rapid Y/W degeneration and simultaneous evolution of dos