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1 children and adults, and does not seem to be rapidly progressive.
2 esence of preceding MS, C9ORF72-ALS was more rapidly progressive.
3 younger than 2 months old at diagnosis with rapidly progressive abdominal disease may benefit from e
11 proteins is the hallmark of the late-onset, rapidly progressive and devastating neurodegenerative di
12 l hypertension (PAH), a disorder that can be rapidly progressive and fatal despite current treatments
15 yotrophic lateral sclerosis (FALS) develop a rapidly progressive and fatal motor neuron disease (MND)
17 Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and fatal neurodegenerative disorder
19 severe crescentic transformation, leading to rapidly progressive and irreversible allograft failure.
22 d mitochondrial respiratory dysfunction, and rapidly progressive and lethal dilated cardiomyopathy.
24 among them that meningococcemia is rare and rapidly progressive and patients are widely dispersed ge
28 human pathogen Pseudomonas aeruginosa causes rapidly progressive and tissue-destructive infections, s
32 fected individuals share a core phenotype of rapidly progressive axonal sensorimotor neuropathy (mani
34 Cochleovestibulopathy commonly presents with rapidly progressive bilateral hearing loss and/or acute
35 e presented to the emergency department with rapidly progressive bilateral visual loss over two days.
36 erm management of corticosteroid-responsive, rapidly progressive, bilateral sensorineural hearing los
38 RF72 cases show the features of a relatively rapidly progressive, but otherwise typical, variant of a
39 f small avascular masses of tumor cells into rapidly progressive cancers is triggered by the angiogen
41 s 4 and 6, alpha-MHC403/403 mice developed a rapidly progressive cardiomyopathy with left ventricular
42 venile onset of myopathy, 8 of whom also had rapidly progressive cardiomyopathy, requiring heart tran
43 -up maximal intimal thickness, >=0.5 mm) and rapidly progressive CAV (maximal intimal thickness, >=0.
44 ed in the diagnostic workup of patients with rapidly progressive central nervous system syndromes, pa
45 ations include structural abnormalities (eg, rapidly progressive cerebellar atrophy), myopathies (inc
46 mutations in the ABCD1 gene, which lead to a rapidly progressive cerebral inflammatory demyelination
47 genetically engineered mouse model develops rapidly progressive chemosensitive neuroblastoma and lac
50 on of manganese in these patients results in rapidly progressive childhood-onset parkinsonism-dystoni
51 mon in adolescent and young adults and has a rapidly progressive clinical course and poor outcome due
52 vations, we hypothesize that during ACS, the rapidly progressive clinical course that can occur is ca
55 e children who died at our institution after rapidly progressive clinical deterioration from this inf
56 e right ventricular failure is a complex and rapidly progressive clinical syndrome, whereby the right
58 While the severe type I mouse model has a rapidly progressive condition mimicking type I SMA in hu
59 e a clinical spectrum ranging from a severe, rapidly progressive congenital or early infantile enceph
61 le in different individuals, spanning from a rapidly progressive course to a long-term asymptomatic i
63 nterferon alpha-2a and ribavirin may trigger rapidly progressive CR in patients with therapeutic immu
64 ce of congenital scoliosis is critical, as a rapidly progressive curve may lead to significant deform
66 al for microRNA (miRNA) processing, leads to rapidly progressive DCM, heart failure, and postnatal le
68 1KI/KI/Reep1-/- mice exhibit early onset and rapidly progressive declines in several motor function t
72 acterized by organic sleep related symptoms, rapidly progressive dementia and sympathetic symptoms.
73 An early and accurate in vivo diagnosis of rapidly progressive dementia remains challenging, despit
74 on-time MR images in an elderly patient with rapidly progressive dementia represents a specific findi
75 ed with HIV clade B, some patients develop a rapidly progressive dementia that if untreated results i
76 eutzfeldt-Jakob disease (sCJD) presents as a rapidly progressive dementia which is usually fatal with
79 The classic triad of symptoms consists of: rapidly progressive dementia, myoclonus and typical elec
82 ly distinguishing treatable from untreatable rapidly progressive dementias and for future therapeutic
84 onditions that typically develop over years, rapidly progressive dementias can develop subacutely ove
85 Creutzfeldt-Jakob disease (CJD) and nonprion rapidly progressive dementias is important and sometimes
86 l adrenoleukodystrophy (CALD) is an X-linked rapidly progressive demyelinating disease leading to dea
87 tic fatal demyelinating disease, because its rapidly progressive demyelination in the nervous system
88 nephritis (GN) is a devastating disease with rapidly progressive deterioration in kidney function, wh
89 ial electrodiagnostic testing demonstrated a rapidly progressive diffuse sensory motor axonopathy, an
90 ve genetic defect in a pair of siblings with rapidly progressive dilated cardiomyopathy and death in
92 Patients with CML in accelerated phase have rapidly progressive disease and are characteristically u
93 ic T lymphocytes (CTL) in an individual with rapidly progressive disease and high levels of viremia.
94 ffers the opportunity to treat patients with rapidly progressive disease and where autologous CAR-T-c
95 isease with no need for immediate therapy to rapidly progressive disease associated with therapeutic
98 tients with multiple sclerosis who display a rapidly progressive disease course and in whom potent ph
99 ommon c.745G>A mutation generally had a less rapidly progressive disease course than the 17 cases wit
100 of these enzymes were strikingly reduced in rapidly progressive disease in homozygous cystic mice an
101 ciency virus (SIV)-infected macaques develop rapidly progressive disease in the apparent absence of d
102 54, B*55, and B*56--has been associated with rapidly progressive disease in white patients with human
103 ity of some M. tuberculosis strains to cause rapidly progressive disease may relate to their intrinsi
105 nti-CTLA4 monoclonal antibody developed more rapidly progressive disease than sham-treated mice, wher
107 ent and incomplete response with evidence of rapidly progressive disease within 2.5 months posttransp
108 enotypic spectrum from infancy (early onset, rapidly progressive disease) to childhood/adolescence an
109 /null mice are normal, Pkd1RC/null mice have rapidly progressive disease, and Pkd1RC/RC animals devel
110 PC1 and PC2 in the kidney exhibited severe, rapidly progressive disease, illustrating the importance
111 nteresting feature of plague is that it is a rapidly progressive disease, suggesting that Y. pestis e
118 ung development, with a phenotype comprising rapidly progressive distal airspace dilation, impaired g
119 y young age at onset, early weight loss, and rapidly progressive dopa-responsive parkinsonism, follow
120 7-year-old Italian boy with childhood-onset rapidly progressive encephalomyopathy and stroke-like ep
122 Acute necrotizing encephalopathy (ANE) is a rapidly progressive encephalopathy that can occur in oth
124 omal acid alpha-glucosidase (Gaa), manifests rapidly progressive fatal cardiac and skeletal myopathy
128 e of the highest-expressing line developed a rapidly progressive fibrotic dilated cardiomyopathy and
129 body titers did not differ between cats with rapidly progressive FIV disease and long-term survivors.
130 irus load is 1 to 2 logs higher in cats with rapidly progressive FIV disease than in long-term surviv
131 al Alzheimer's disease clinical subtypes-the rapidly progressive form (r-AD) and the posterior cortic
132 ing the pathogenetic mechanisms of this most rapidly progressive form of focal segmental sclerosis is
134 Fibrosing cholestatic hepatitis (FCH) is a rapidly progressive form of viral hepatitis B that occur
135 c HDV infection commonly results in the most rapidly progressive form of viral hepatitis; it is the c
136 se requiring only brief hospitalization to a rapidly progressive, fulminant illness resulting in the
139 s unique periodontal presentation were pain, rapidly progressive gingival recession, and significant
140 sease were 2.33 times more likely to develop rapidly progressive glaucoma disease despite significant
141 merular basement membrane (GBM) disease is a rapidly progressive glomerulonephritis (GN) resulting fr
144 ococcal glomerulonephritis, IgA nephropathy, rapidly progressive glomerulonephritis (RPGN), and membr
145 iated vasculitis is the most common cause of rapidly progressive glomerulonephritis and immune-mediat
146 the use of PLEX to rescue organ function in rapidly progressive glomerulonephritis and lung haemorrh
148 Rapidly progressing AVCD is analogous to rapidly progressive glomerulonephritis in that inner ear
150 tation with full blown nephritic syndrome or rapidly progressive glomerulonephritis is uncommon and i
151 ciated vasculitis (AAV) is a common cause of rapidly progressive glomerulonephritis resulting in end-
152 e as a potential therapeutic intervention in rapidly progressive glomerulonephritis, we treated mice
160 e focal segmental glomerulosclerosis (FSGS), rapidly progressive glomerulonephritis/idiopathic cresce
161 the formation of both cellular crescents in rapidly progressive GN and sclerotic lesions in FSGS.
162 otoxic serum to induce crescentic nephritis (rapidly progressive GN), this genetic inactivation of th
165 HL) is characterized typically by bilateral, rapidly progressive hearing loss that responds therapeut
166 virus (EBOV) and Marburg virus (MARV) cause rapidly progressive hemorrhagic fever with high mortalit
169 ocrine cancers that are widely metastatic or rapidly progressive, however, the role of the medical on
170 dema appears to be decreasing, patients with rapidly progressive (hyperacute) liver failure, such as
171 lar mesenchymal cells of human subjects with rapidly progressive idiopathic pulmonary fibrosis (IPF).
176 specific immune responses over the course of rapidly progressive infection are not well defined.
178 acid (AAI) nephropathy (AAN) is a common and rapidly progressive interstitial nephropathy caused by i
179 RGMc) cause juvenile hemochromatosis (JH), a rapidly progressive iron overload disorder in which expr
180 HIV-associated nephropathy (HIVAN) is a rapidly progressive kidney disease that is caused by HIV
182 However, in mouse infections, after a delay rapidly progressive lesions appeared, and purified amast
183 tosomal dominant inheritance of a late onset rapidly progressive leukodystrophy in which exome sequen
184 he clinical details of three patients with a rapidly progressive, levodopa-unresponsive bradykinetic-
189 hepatitis C appears to cause more severe and rapidly progressive liver disease leading more frequentl
190 mia survivors with chronic HCV may have more rapidly progressive liver disease than has been previous
195 er the next 3 months, serial audiograms show rapidly progressive loss of threshold and word recogniti
196 t-3-deleted mice to 95% oxygen caused a more rapidly progressive lung injury associated with alveolar
198 included early lethal encephalopathies with rapidly progressive massive brain atrophy, severe develo
199 a Minnesota resident, aged 7 years, died of rapidly progressive meningoencephalitis after local fres
200 Ethylmalonic encephalopathy is a fatal, rapidly progressive mitochondrial disorder caused by ETH
202 ion of ILK in Pkd1(fl/fl) ;Pkhd1-Cre mice, a rapidly progressive model of ADPKD, decreased renal Akt/
204 hQ200 mice is paralleled by earlier and more rapidly progressive motor deficits: progressive imbalanc
206 al care unit for evaluation and treatment of rapidly progressive motor weakness and encephalopathy.
207 ly Hdh(neoQ20)/Hdh(neoQ111) mice exhibited a rapidly progressive movement disorder that, in the absen
209 Acute liver failure can be associated with rapidly progressive multiorgan failure and devastating c
212 nsthyretin-mediated (hATTR) amyloidosis is a rapidly progressive, multisystem disease that presents w
213 ine spinal muscular atrophy (HCSMA) features rapidly progressive muscle weakness that affects muscles
214 and lower motor neuron dysfunction and loss, rapidly progressive muscle weakness, wasting and death.
215 a new recessive mouse mutation that causes a rapidly progressive muscular dystrophy and a neonatal fo
219 port defects have also been observed in more rapidly progressive neurodegeneration, such as that obse
220 Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disease of motor n
221 lateral sclerosis is a relatively common and rapidly progressive neurodegenerative disease that, in t
222 y form of X-linked adrenoleukodystrophy is a rapidly progressive neurodegenerative disease, as devast
223 c lateral sclerosis (ALS) is one of the most rapidly progressive neurodegenerative diseases of unknow
226 Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder due to se
227 zheimer's disease and Parkinson disease, are rapidly progressive neurodegenerative disorders caused b
228 n levels induce SMA pathology by instigating rapidly progressive neurodegenerative pathways in lower
229 l (COFS) syndrome is a recessively inherited rapidly progressive neurologic disorder leading to brain
231 ro-oculo-facio-skeletal (COFS) syndrome is a rapidly progressive neurological disorder leading to bra
232 SF RT-QuIC testing in 2,141 patients who had rapidly progressive neurological disorders, determined d
235 besity and nutrition in the development of a rapidly progressive nonalcoholic steatohepatitis phenoty
236 imeric murine oncornavirus FrCas(E) causes a rapidly progressive noninflammatory spongiform encephalo
239 We describe 2 Greek siblings who developed a rapidly progressive oculopharyngeal somatic syndrome, at
241 f knowledge about the mechanisms involved in rapidly progressive osteoarthritis are also discussed an
242 of NGF inhibitors also increased the risk of rapidly progressive osteoarthritis in a small percentage
243 istration of the same antibodies in the more rapidly progressive P301S tauopathy model not only reduc
244 31-year-old Caucasian female presented with rapidly progressive painful proptosis of the right eye a
245 Highly aggressive Burkitt lymphoma (BL) with rapidly progressive painful proptosis of the right eye i
246 nerative disease characterized clinically by rapidly progressive paralysis leading ultimately to deat
248 imeric murine oncornavirus FrCas(E) causes a rapidly progressive paralytic disease associated with sp
249 neurodegenerative disorder characterized by rapidly progressive parkinsonism-dystonia in childhood.
252 rly-onset periodontitis (G-EOP, encompassing rapidly progressive periodontitis and generalized juveni
253 by hyperkeratosis of the palms and soles and rapidly progressive periodontitis resulting in loss of d
257 Within 31 months, six imatinib-resistant rapidly progressive peritoneal implants (metastatic foci
258 ing this autoregulatory mechanism produces a rapidly progressive phenotype and dose-dependent lethali
259 ith digenic animals exhibiting phenotypes of rapidly progressive PKD and early lethality resembling c
260 ely progressive PKD), kidneys from cpk mice (rapidly progressive PKD), and human autosomal dominant P
264 deficiency (MoCD) is characterised by early, rapidly progressive postnatal encephalopathy and intract
266 eness, and between patients with typical and rapidly progressive presentations of neurodegenerative d
267 promotes both reactivation TB from LTBI and rapidly progressive primary TB following recent exposure
268 ) with associated necrotizing fasciitis is a rapidly progressive process that kills 30-60% of patient
269 ossible to recognise that some patients with rapidly progressive psychiatric symptoms or cognitive im
271 o Jan 31, 2009, in patients with metastatic, rapidly progressive, radioiodine-refractory differentiat
272 that develop a severe glomerulosclerosis and rapidly progressive renal disease overexpress IL-4 in vi
273 en 20 years since the first description of a rapidly progressive renal disease that is associated wit
275 SP-B gene (121ins2) and is characterized by rapidly progressive respiratory failure immediately afte
277 of ocular involvement and the potential for rapidly progressive retinal vascular abnormalities and d
280 respiratory distress syndrome (ARDS) that is rapidly progressive, severe, and refractory to conventio
281 cocci (CoNS) that is responsible for severe, rapidly progressive skin and soft tissue infections and
282 riant of Friend MuLV (F-MuLV) which causes a rapidly progressive spongiform neurodegenerative disease
286 diabetic guinea pigs resulted in severe and rapidly progressive tuberculosis (TB) with a shortened s
287 olochic acid nephropathy is characterized by rapidly progressive tubulointerstitial nephritis culmina
288 ogic and clinical features, characterized by rapidly progressive tumors with high rates of extranodal
289 y healthy child who developed acute, severe, rapidly progressive vanishing bile duct syndrome shortly
291 l follow-up of 5.9 years, more patients with rapidly progressive vasculopathy died, as compared with
296 N) is a disorder characterized by severe and rapidly progressive visual loss when caused by a mutatio
297 ozygous Tk2 mutant (Tk2(-/-)) mice developed rapidly progressive weakness after age 10 days and died
298 disorder characterized by motor neuron loss, rapidly progressive weakness and early death has been co