ライフサイエンスコーパス: rarity

1 PTID) have not been established due to their rarity.

2 on2 remain uncertain because of its relative rarity.

3 e frequencies (MAF) < 0.1%, indicating their rarity.

4 difficult to conduct because of the disease rarity.

5 appropriate to present this case due to its rarity.

6 the species' conservation status and global rarity.

7 the artery of Adamkiewicz, which is another rarity.

8 ey are considered introductions due to their rarity.

9 ult because of its asymptomatic features and rarity.

10 ndividuals, where aggregation increases with rarity.

11 en hindered by high diversity and consequent rarity.

12 ary significance of parasex and its apparent rarity.

13 zyme mechanisms have obscured its parametric rarity.

14 -dependent cost to commonness and benefit to rarity.

15 een limited due to their reactive nature and rarity.

16 ces from formally described species remain a rarity.

17 FIF is a pediatric rarity.

18 rs, appear to be incompatible with sustained rarity.

19 esidents, after controlling for MHC genotype rarity.

20 genomic profiling remains limited given its rarity.

21 to treatment and strikingly, in view of its rarity a genome-wide association study has identified a

22 w similar rates of scaling in commonness and rarity across microorganisms and macroscopic plants and

23 ed questions remain about how common chronic rarity actually is, which traits are consistently associ

24 Because of its rarity, acute liver failure has not been studied in larg

25 One consequence of their rarity among sarcomas, as well as their biologic and cli

26 ered flight potential in early birds but its rarity among the ancestors of the closest avialan relati

27 Despite its rarity, anaphylaxis is a potentially life-threatening me

28 n misdiagnosed before surgery because of its rarity and a lack of awareness of the condition by clini

29 However, despite its rarity and absence in large sudden death cohorts, TKOS r

30 Because of the rarity and aggressive nature of malignant thyroid mesenc

31 Different interpretations of rarity and co-occurrence with pathogenic variants contri

32 Despite their relative rarity and complexity, most porphyrias can be easily def

33 Diagnosis is often missed due to its rarity and confusing definitions of the Foix-Alajouanine

34 d has defied proper treatment trials for its rarity and deadly behavior.

35 us is a challenging condition because of its rarity and dismal prognosis.

36 ve molecular characterization because of the rarity and diversity of cells.

37 Given their rarity and diversity, the idiopathic inflammatory myopat

38 tion trends were poorly captured by species' rarity and global-scale threats.

39 is is poorly understood due, in part, to the rarity and heterogeneity of the affected hematopoietic p

40 ood are still elusive because of the extreme rarity and heterogeneity of the cells.

41 s of IIMs remains limited in part due to the rarity and heterogeneity of these disorders.

42 NETs have been poorly defined because of the rarity and heterogeneity of these neoplasms.

43 Reflecting their rarity and heterogeneity, Pan-NENs represent a clinical

44 me both reduced statistical power because of rarity and higher population divergence.

45 Owing to their rarity and histologic overlap, accurate diagnosis of sar

46 st 1358 have been awarded, and, due to their rarity and historic interest, have become highly prized

47 the condition is challenging because of its rarity and its difficulty to diagnose.

48 n among some derived tyrannosaurids, but the rarity and juvenile nature of these fossils leaves many

49 ) manifestations, but the combination of the rarity and lack of in-depth reporting often limit our un

50 uch patients in isolation is hindered by the rarity and novelty of such disorders.

51 cal procedure at varying levels of cell type rarity and other experimental parameters.

52 Rarity and phylogenetic rarity - direct measures of the

53 In fact, the rarity and poorer preservation of the sphenodiscids rela

54 ess have seldom been visualized due to their rarity and rapidity.

55 f genetic causes which due to their relative rarity and sometimes variable and overlapping presentati

56 ty that an aposematic prey can increase from rarity and spread across a large population.

57 The relative rarity and unpredictability of esophageal perforation ha

58 The rarity and unpredictability of the disorder have signifi

59 ng genetic diseases affecting the eyelids on rarity and whether the disease manifests itself at birth

60 its are consistently associated with chronic rarity, and how chronically rare species are distributed

61 ue to its relationship with extinction risk, rarity, and invasiveness, but it also provides insights

62 Given its rarity, and paucity of randomized trials, the nuances of

63 Given its unique biology, relative rarity, and the difficulty in achieving long-lasting rem

64 riable clinical presentation, their relative rarity, and the overlap of the signs and symptoms of vas

65 e factors determining species commonness and rarity are poorly understood, particularly in highly div

66 ose with greatest "evolutionary distinctness rarity") as well as some of the most imperiled distinct

67 -especially for forests-due to feedback from rarity-based conservation decisions.

68 Echinococcal involvement of the spine is a rarity but needs to be considered in the differential di

69 cies into four weighted categories of global rarity called Stars.

70 This case highlights the rarity caudal regression syndrome in a foetus of a non-d

71 Because of their rarity, centralised pathology and treatment, and nationa

72 Despite its relative rarity, CIDP represents a significant economic burden, m

73 of isotype-switched CLL, which, despite its rarity, contributes intriguing ontogenetic hints.

74 Rarity declined from natural forest to planted forest, g

75 Because of this rarity, developing cohorts with enough individuals to ro

76 Due to expense and rarity, developing synthetic protocols that reduce preci

77 r, because of their heterogeneous nature and rarity, diagnosis and treatment of these disorders eithe

78 Rarity and phylogenetic rarity - direct measures of the number of species or the

79 mmigrating into a community may experience a rarity disadvantage due to competition for the services

80 ease incidence, but coyote abundance and fox rarity effectively predict the spatial distribution of L

81 However, species valued for their rarity, endemism, and evolutionary distinctness declined

82 Shared variants were filtered for rarity, evolutionary conservation, and predicted functio

83 Overall, phylogenetic rarity explained the highest proportion of land use-rela

84 patterns to chemotherapy, and despite their rarity, future trials will need to emphasize specific hi

85 Despite their perceived rarity, gastroenteropancreatic neuroendocrine tumors (GE

86 ation emphasis should be given to ecological rarity given future environmental conditions and the nee

87 Despite its rarity, group P shows evidence of adaptation to humans.

88 n hard drives at room temperature, and their rarity has motivated many fundamental studies in materia

89 Its relative rarity has prevented prospective study of the entity.

90 e of nitric oxide in this nucleus, but their rarity has so far prevented systematic studies.

91 Despite their rarity, IGH chromosomal translocations in BCP-ALL theref

92 out the body ensures that, in spite of their rarity, ILCs are able to regulate immune homeostasis eff

93 ) MBCs in humans, demonstrated their extreme rarity in circulation and cautioned against the clinical

94 key phenomena: (i) the relative lateness and rarity in geological time of the emergence of eusocialit

95 wn about the amorphous Li2 O2 because of its rarity in high purity.

96 w diversity does not explain N-fixing trees' rarity in higher-latitude forests.

97 th rare frequency in East Asians but extreme rarity in other populations were associated with alanine

98 n analysis, functional characterization, and rarity in public databases.

99 eted either at random, or according to their rarity in the assemblage, to assess to what extent patte

100 However, due to their rarity in the general population, these founders have be

101 s consistent with patterns of commonness and rarity in the marine biosphere.

102 mobilia in children after liver biopsy are a rarity in the scientific literature because there are on

103 mobilia in children after liver biopsy are a rarity in the scientific literature because there are on

104 anced diabetic nephropathy in humans, so its rarity in typical rodent models may partly explain their

105 lian body size distributions and patterns of rarity in worldwide plant communities.

106 Rarity is a population characteristic that is usually as

107 eir evolutionary distinctness and geographic rarity is a surprisingly effective and spatially economi

108 Explaining patterns of commonness and rarity is fundamental for understanding and managing bio

109 One hypothesis for their rarity is that evolutionary constraints limit N-fixing t

110 is integrative approach can solve the sample rarity issue in the neuroscience.

111 Despite its rarity, it is imperative for a radiologist to be aware o

112 Despite its rarity, it represents the major cause of acute liver fai

113 Research into SSc has been hampered by its rarity, its clinical heterogeneity, and the lack of mous

114 ate that reduced RNA structure and not codon rarity itself is responsible for expression increases.

115 was conducted using filters based on variant rarity (less than one in 10,000 or private), computation

116 te variant-gene relevance score based on the rarity, location and predicted pathogenicity of variants

117 This rarity makes it daunting to select a CT and MRI protocol

118 e are still under debate, and their supposed rarity makes modelling their formation difficult(7,8).

119 This dependence and the cofactor's rarity may make F(420)-related proteins promising drug t

120 Mass rarity may provide the most robust measure of our curren

121 on all aspects of PTLD is limited due to its rarity, morphologic heterogeneity, and the lack of prosp

122 Because of their perceived rarity, NETs have not historically been a focus of rigor

123 Because of their rarity, no randomized trials have been reported and many

124 ered in the NP likely contribute to relative rarity of 11E among carriage isolates, whereas selective

125 Because of the rarity of AEF, evaluation and validation of strategies t

126 Because of the relative rarity of AgP in the population, and attendant difficult

127 The rarity of altruistic punishment in small-scale societies

128 However, due to the rarity of antimatter and weakness of the gravitational f

129 Our findings may explain the rarity of apoptosis but the inevitable cell death associ

130 naccessibility of autoimmune tissues and the rarity of autoimmune T cells in the blood hinder their s

131 The relative rarity of basophils and their phenotypic similarities wi

132 ssible but difficult, potentially due to the rarity of bNAb clones and their precursors.

133 The rarity of both birth defects and childhood cancers makes

134 Because of the rarity of brain samples from living humans with VZV ence

135 In neuroscience, the rarity of brain tissue is the bottleneck for such study.

136 Given the rarity of BRCA1 mutations in sporadic ovarian cancers, w

137 stion has remained unanswered because of the rarity of cases of late sight onset.

138 t on the number of single cells isolated and rarity of cell types to be identified.

139 possibly ornithomimosaurs), and the relative rarity of ceratosaurs, is strikingly dissimilar to penec

140 Our results highlight the rarity of chromosome copy number alterations across mamm

141 about their short-term impact because of the rarity of clinical events.

142 temperatures is occurring worldwide, but the rarity of co-occurring long-term observational and tempe

143 In view of the rarity of coenzyme Q(10) deficiency, we hypothesized tha

144 o be present in humans and contribute to the rarity of commotio cordis.

145 The apparent rarity of contingent cooperation in animals has convince

146 porting others, suggesting that the apparent rarity of contingent cooperation in primates may not ste

147 tely 60 years) is largely unknown due to the rarity of continuously sustained biological observations

148 of isolating these cells is arduous, and the rarity of CSCs makes it difficult to test potential drug

149 The rarity of CTCs in peripheral blood has driven the develo

150 wever, in mice, limited blood volume and the rarity of CTCs in the bloodstream preclude longitudinal,

151 The rarity of cumulative culture in nature may result from t

152 ality inside prisons can be explained by the rarity of deaths unlikely to occur in the context of inc

153 degree of underestimation increases with the rarity of disease, the heritability of the disease, and

154 The rarity of disruptive mutations among unaffected individu

155 disorders in chILD, in combination with the rarity of each diagnosis, has hampered scientific and cl

156 verse pathophysiologies of the PIDDs and the rarity of each disorder, data are often lacking, leading

157 ncestral body size suggests that the extreme rarity of early ornithodirans in the fossil record owes

158 Because of the relative rarity of ECD, key clinical features of the disease may

159 The rarity of elemental iodine and I(-) in the environment c

160 However, given the rarity of endophthalmitis following DEX and the heteroge

161 The rarity of failures argues that safety factor is high und

162 n into such compounds are lacking due to the rarity of fluorine in nature.

163 However, the rarity of fossilized CNSs, even when exoskeletons and ap

164 The rarity of full brain viral infections raises the importa

165 Due to the rarity of GPS, it has been difficult to fully understand

166 Prior research has been limited by the rarity of HL and the requirement for extended follow-up

167 diagnosis may be challenging because of the rarity of HLH, its variable presentation, and the time r

168 inhabited by 22 million people; however, the rarity of human outbreaks emphasises the very low probab

169 These studies have been thwarted by the rarity of IgE(+) cells in vivo and the low frequency of

170 Diagnosis is challenging because of the rarity of ILD and the fact that the presenting symptoms

171 s in human physiology is strengthened by the rarity of inactivating mutations in their genes and by t

172 antial change in the relative commonness and rarity of individual species, indicating considerable tu

173 small sample size, which was a result of the rarity of individuals presenting during hyperacute infec

174 de almost complete striatal degeneration and rarity of intranuclear inclusions in HD, and the fact th

175 lost in large continuous forests due to the rarity of large-bodied mammalian frugivores.

176 antification of this risk is hampered by the rarity of long-term data for multiple interacting specie

177 cal or inferred through phylogeny due to the rarity of meaningful fossils.

178 reactivity of bNAbs surely contribute to the rarity of membrane-proximal external region (MPER) and C

179 Because of the rarity of MF/SS, only a large collaboration would power

180 ambrian life is still unknown because of the rarity of microbial fossils and biomarkers.

181 Due to the rarity of monomorphic T-cell PTLD (T-PTLD), knowledge ab

182 The rarity of most high-impact genetic variants typically pr

183 Due to the extreme rarity of mutations and high-dimensionality, significanc

184 g HIV vaccine designs because of the in vivo rarity of naive B cells that recognize broadly neutraliz

185 s (rapid cheat invasion) may account for the rarity of natural disease outbreaks caused by B. thuring

186 ses provides a potential explanation for the rarity of Neu5Gc in the vertebrate brain.

187 WHERE NEXT?: Despite the rarity of neuromyelitis optica spectrum disorder, a rela

188 The rarity of nitrogen (N)-fixing trees in frequently N-limi

189 Given the rarity of NPCs, the long history of NPC cell lines, and

190 Although the rarity of nuclear disasters limits opportunities to unde

191 out individual and group responses given the rarity of observed predation events.

192 Evaluation of the rarity of observing particular ranges for these characte

193 rventricular septal aneurysm, because of its rarity of occurrence and complications.

194 rventricular septal aneurysm, because of its rarity of occurrence, complication in the form of thromb

195 Because of its rarity of occurrence, no multivariable analysis of risk

196 y and reduction of hindlimbs [8-11], but the rarity of Oligocene whale skeletons [12, 13] has hampere

197 The rarity of our patient suggests the influence of modifier

198 Given the rarity of patient-matched samples, no exclusion criteria

199 incidence increased with age, but due to the rarity of PCNs in younger people in the general populati

200 This may help explain the rarity of PDAC in persons with chronic inflammatory cond

201 The rarity of pediatric glomerular disease makes it difficul

202 in vitro and in vivo, likely explaining the rarity of plasmid-deficient isolates in nature.

203 Despite the rarity of PMCR among clinical isolates in the United Sta

204 The rarity of PMP in humans makes evaluation of the disease

205 Despite the rarity of POC, it is imperative for a radiologist to be

206 We extrapolate from this to suggest that the rarity of polyploidy in gymnosperms may be due to slow d

207 e infant oral/gastrointestinal tract and the rarity of postnatal virus transmission in natural hosts

208 challenge this approach by showing that the rarity of previously abundant taxa may be more important

209 use of the overlapping features and relative rarity of PS, we hypothesized that some patients in whom

210 Rarity of recombination between the closely linked and p

211 The histologic diversity and rarity of retroperitoneal sarcoma has hampered the abili

212 Owing to the rarity of severe necrotising enterocolitis, internationa

213 nding group of human viruses and explain the rarity of some novel polyomavirus-associated diseases.

214 Owing to the rarity of some of these forms and a general lack of comp

215 his complex landscape could explain both the rarity of specialists across many similar environments d

216 Our results (i) explain the rarity of strain-transcending P. falciparum infection bl

217 een relatively few in number, suggesting the rarity of such associations and of such a predisposition

218 Lake Balls in nature seems to be due to the rarity of such environmental conditions.

219 The rarity of such extreme events and the response of the so

220 The rarity of such genes indicates that few genes escape X i

221 wheat, however, genic redundancy results in rarity of such mutants, with the ethyl methanesulfonate-

222 nges will exist in doing this because of the rarity of suicide even among patients considered high-ri

223 The rarity of symbiotic nitrogen (N)-fixing trees in tempera

224 cancer immunotherapy remains limited by the rarity of targetable tumor-specific antigens, tumor-medi

225 The extremely ancient age combined with the rarity of the A00 lineage, which we also find at very lo

226 lity in laboratory approaches as well as the rarity of the complication act as a barrier to future st

227 The rarity of the disease and difficulty in diagnosis contri

228 Because of the rarity of the disease and limited available data, the st

229 have been uncovered in IL36RN and AP1S3, the rarity of the disease has hindered the study of genotype

230 The rarity of the disease has stymied therapeutic developmen

231 and geographic distribution of cases and the rarity of the disease make it unlikely that data from ra

232 However, because of the rarity of the disease, the disease frequently remains an

233 The true incidence may be confounded by the rarity of the disorder, with a resultant lack of appreci

234 he HMB-45 negativity may be explained by the rarity of the epithelioid cells, and the HMB-45 positivi

235 rate of disruption is lacking, owing to the rarity of the events.

236 ndered by potential heterogeneity and by the rarity of the implicated alleles.

237 differential diagnosis either because of the rarity of the infection, because the microorganism has n

238 well studied in mammals, due in part to the rarity of the latter.

239 Due to the rarity of the mutant events, rare variants are routinely

240 The rarity of the outcome limited the number of variables in

241 s usually need large sample sizes due to the rarity of the variants, and large sample sizes typically

242 atomy of the developing spine as well as the rarity of their occurrence.

243 Owing to the rarity of these 2 diseases, patients with co-occurrence

244 ffer significant benefit, but because of the rarity of these cancers, novel therapies are slow to dev

245 Given the rarity of these childhood tumors and their propensity to

246 Yet, owing to the rarity of these disorders, little clinical evidence rega

247 resia through clinical trials because of the rarity of these disorders.

248 However, the rarity of these events has created challenges for the id

249 ocular adnexal neoplasms; however, given the rarity of these neoplasms, large epidemiological studies

250 The rarity of these neoplasms, the limited knowledge of thei

251 treatment options in clinical trials is the rarity of these subtypes.

252 Given the rarity of these tumors and the lack of clinical trials t

253 mic malignancies is difficult because of the rarity of these tumors.

254 Given the rarity of these tumours, efforts to optimize infrastruct

255 ailable genotype databases, we confirmed the rarity of these variants in European populations but sho

256 The rarity of these variants makes it challenging to evaluat

257 ed by CD4bs bNAbs offers a mechanism for the rarity of this bNAb class.

258 We discussed the rarity of this condition and its management.

259 Because of the rarity of this condition, information on pregnancy-assoc

260 Despite the rarity of this condition, it is important to know that h

261 l sequence variation in JCPyVAN owing to the rarity of this condition.

262 The rarity of this disease, along with lack of nodal involve

263 Because of the relative rarity of this disease, its molecular drivers and optima

264 Because of the rarity of this disease, little is known about optimal tr

265 Because of the rarity of this disease, the molecular mechanisms regulat

266 l benefit remains challenging because of the rarity of this disease.

267 ategies remain undetermined, in light of the rarity of this disease.

268 s a paucity of prospective data owing to the rarity of this disease.

269 The rarity of this disorder and the complexity of its clinic

270 h tyrosine kinase inhibitors (TKIs), but the rarity of this leukemia in children and adolescents make

271 fatal anaphylaxis are limited because of the rarity of this outcome.

272 as no greater than small, given the relative rarity of thyroid cancer, the apparent lack of differenc

273 However, the rarity of tumor-reactive T cells in cancer patients, the

274 his approach, however, is constrained by the rarity of tumor-specific single antigens.

275 inal stromal tumor is an uncommon tumor, the rarity of which has made both laboratory research studie

276 ibuted to the paucity of young elements; the rarity of young LTR-RTs is a consequence of fewer births

277 Its heterogeneity and rarity often result in underpowered clinical trials maki

278 To overcome this cellular heterogeneity and rarity problem, we have developed multicolor QD-antibody

279 s of land use on soil invertebrates, whereas rarity provides clearer and more consistent evidence of

280 ng our daily interactions with objects are a rarity rather than the norm.

281 Such conservation of rarity-rather than specific codon identity-could coordin

282 ity, spatial extent, recording potential and rarity recording.

283 r rocks are rare, they are not absent: their rarity reflects the low diversity of life at this time,

284 This rarity reinforces the concept of folds as reusable units

285 Despite its rarity, Schnitzler syndrome is an important diagnosis as

286 Using a range-rarity scoring method we identified where clusters of en

287 However, the rarity, secretive behaviours and obscure microhabitats o

288 vaccine candidate, but due to their previous rarity, serotype 35B strains have not been scrutinized f

289 opment index are also hotspots of ecological rarity, suggesting transboundary responsibility for thei

290 Because of its rarity, the clinical and biological features of WDSM rem

291 Because of its rarity, the diagnosis and specific treatment of XLH are

292 is challenging to investigate because of its rarity, the lack of experimental models, the number of m

293 tedly been poor, but because of its relative rarity, the natural history remains incompletely charact

294 d and rejected as explanations for arthropod rarity; the preserved biota is considered to be an appro

295 Due to disease rarity, there is limited information regarding the optim

296 to be identified, and given their increasing rarity, this will require large-scale collaboration that

297 ation allows cooperative alleles to overcome rarity thresholds and invade bacterial populations struc

298 ortion in transition, either to abundance or rarity, thus offering a first view on how it varies acro

299 ency of HSCs depicted with imaging and their rarity when measured with limiting dilution transplant.

300 dons change from organism to organism, codon rarity will be conserved at specific positions in a set