ライフサイエンスコーパス: reactive nitrogen species

1 ion are dependent on protein modification by reactive nitrogen species.

2 ction or denitrification, bacteria encounter reactive nitrogen species.

3 as a biomarker of oxidative stress caused by reactive nitrogen species.

4 ) whose products are thought to remove toxic reactive nitrogen species.

5 hat counteract the effects of NO and related reactive nitrogen species.

6 se (iNOS) and increased production of NO and reactive nitrogen species.

7 ake, are major regulators of the response to reactive nitrogen species.

8 thers that are collaterally activated by the reactive nitrogen species.

9 prevent nitration of tyrosines caused by the reactive nitrogen species.

10 ese effects on TH of tetrahydrobiopterin and reactive nitrogen species.

11 reactivity and the interaction of CcOX with reactive nitrogen species.

12 e pathogen from the antimicrobial actions of reactive nitrogen species.

13 intracellular reactive oxygen species (ROS)/reactive nitrogen species.

14 tions and has been linked to the presence of reactive nitrogen species.

15 mage: hydroxyl radical, tyrosyl radical, and reactive nitrogen species.

16 d LDL and LDL modified by monocyte-generated reactive nitrogen species.

17 oprotein damage induced by this pathological reactive nitrogen species.

18 molecules, can also lead to the formation of reactive nitrogen species.

19 ts a specific marker of protein oxidation by reactive nitrogen species.

20 undergo abiotic transformations mediated by reactive nitrogen species.

21 up-regulated activity of enzymes, generating reactive nitrogen species.

22 nitric oxide synthase and the production of reactive nitrogen species.

23 ate that circumvents the negative effects of reactive nitrogen species.

24 is sensitive to exogenously supplied ROS and reactive nitrogen species.

25 ble mechanism for recycling nitrate anion to reactive nitrogen species.

26 of beta-cells to reactive oxygen species and reactive nitrogen species.

27 eduction product of NO, remains an enigmatic reactive nitrogen species.

28 eduction to nitrite, nitric oxide, and other reactive nitrogen species.

29 ent of macrophages that produce microbicidal reactive nitrogen species.

30 H antagonizes the bacteriostatic activity of reactive nitrogen species.

31 r exposure to host-like stresses, especially reactive nitrogen species.

32 erium to overcome the toxicity of Fe(II) and reactive nitrogen species.

33 e to redox modifications of its SH groups by reactive nitrogen species.

34 ed to higher optical emission intensities of reactive nitrogen species (328-426 nm), hydroxyl radical

35 ve oxygen species or decreased production of reactive nitrogen species, a situation of nitroso-redox

36 Thus, a reactive nitrogen species acts directly on the channel o

37 nd transcriptional regulation in response to reactive nitrogen species, allowing the bacteria to face

38 Reactive nitrogen species also reacted with emtricitabin

39 O when tested against other common gas-phase reactive nitrogen species, although loss of O(3) on Nafi

40 mportant role in the spatial distribution of reactive nitrogen species and consequently in ozone form

41 oncentrations of reactive oxygen species and reactive nitrogen species and contributes to tissue prot

42 formation: for example, reactive oxygen and reactive nitrogen species and elevated levels of DNA mut

43 thways available to monocytes for generating reactive nitrogen species and explored their potential c

44 (8-NO(2)-dG) DNA adducts are induced by the reactive nitrogen species and may be associated with the

45 ion pathway extends the apparent lifetime of reactive nitrogen species and modifies the atmospheric o

46 The study highlights the involvement of reactive nitrogen species and nitric oxide (NO) on autop

47 NH(3) combustion may introduce reactive nitrogen species and organic byproducts that af

48 This interaction between reactive nitrogen species and PGHS may provide new appro

49 gamma-Tocopherol is effective scavengers of reactive nitrogen species and prevents DNA bases nitrati

50 is theory predicts that interactions between reactive nitrogen species and reactive oxygen species pr

51 e for ytfE in resistance of H. influenzae to reactive nitrogen species and the antibacterial effects

52 can be used to identify proteins modified by reactive nitrogen species and to determine the specific

53 aptive response to nitric oxide (NO)-derived reactive nitrogen species and to iron limitation in the

54 They also show that reactive nitrogen species and tyrosyl radical (and conse

55 hese in vivo and in vitro findings implicate reactive nitrogen species and tyrosyl radical in MPTP ne

56 ature, hypoxia, reactive oxygen species, and reactive nitrogen species) and in bioimaging (lymph node

57 ants (e.g., O2, reactive oxygen species, and reactive nitrogen species) and toxic levels of certain m

58 duced antimicrobial reactive oxygen species, reactive nitrogen species, and autophagy pathways and in

59 endent induction of reactive oxygen species, reactive nitrogen species, and autophagy.

60 clerotic lesions implicates tyrosyl radical, reactive nitrogen species, and hypochlorous acid in LDL

61 kill phagocytosed Escherichia coli, produce reactive nitrogen species, and retain S. Typhimurium wit

62 precursors include reactive oxygen species, reactive nitrogen species, and sulfur dioxide.

63 composed of various reactive oxygen species, reactive nitrogen species, and UV photons, shows great p

64 Reactive oxygen species and reactive nitrogen species are biological molecules that

65 There is evidence that reactive nitrogen species are implicated in diabetic vas

66 ps susceptible to transformations by AMO and reactive nitrogen species are systematically classified.

67 f labile Zn(2+), and its inter-relation with reactive nitrogen species, are poorly understood due to

68 phils generate reactive oxygen species (ROS)/reactive nitrogen species as a defense mechanism for the

69 tively, these results identify MPO-generated reactive nitrogen species as a physiologically plausible

70 (91)), a major source of microglial ROS, and reactive nitrogen species as candidate inhibitors of NPC

71 Major host insults are reactive oxygen and reactive nitrogen species as well as cellular stress ind

72 sis, and defense against reactive oxygen and reactive nitrogen species, as key determinants of its pa

73 sulted in sensitivity to reactive oxygen and reactive nitrogen species, as well as increased DNA dama

74 erate sustainable high concentrations NO and reactive nitrogen species at tumor sites after treatment

75 ought to be driven by production and loss of reactive nitrogen species by microorganisms in the soil.

76 n determining how DA neurons are affected by reactive nitrogen species by shifting the balance of the

77 etoxification of reactive oxygen species and reactive nitrogen species can protect neurons.

78 lative nitrations of Y190, Y317, and Y380 by reactive nitrogen species cause destabilization of CYP2B

79 ify a pathological signaling cascade whereby reactive nitrogen species cause S-nitrosylation of TDP-4

80 osure to C. jejuni and that nitric oxide and reactive nitrogen species comprise part of the innate de

81 A kinetic model indicated that reactive nitrogen species could be important to the phot

82 ntial targets of reactive oxygen species and reactive nitrogen species could contribute to ERK1/2 act

83 d macrophages, and the resultant increase in reactive nitrogen species damages axons by injuring thei

84 Furthermore, reactive nitrogen species derived from internalized and

85 otyrosine in HDL raises the possibility that reactive nitrogen species derived from nitric oxide migh

86 lycoxidation, the enzyme myeloperoxidase, or reactive nitrogen species derived from nitric oxide.

87 In addition, reactive nitrogen species derived from NO can display an

88 FAs) are the product of the reaction between reactive nitrogen species derived of nitric oxide (NO) a

89 We report the generation of these reactive nitrogen species during automotive braking usin

90 al (lipid peroxidation) and 3-nitrotyrosine (reactive nitrogen species formation) protein adducts cau

91 to tyrosine nitration in vivo; 2) the major reactive nitrogen species formed by leukocyte peroxidase

92 Reactive nitrogen species formed from nitric oxide (NO)

93 Reactive nitrogen species, formed during oxidative stres

94 We conclude that reactive nitrogen species generated by iNOS cooperate wi

95 Recent studies have identified reactive nitrogen species generated by monocytes by way

96 Our observations raise the possibility that reactive nitrogen species generated by myeloperoxidase a

97 We now report that reactive nitrogen species generated by the MPO-H2O2-NO2-

98 sion patterns of reactive oxygen species and reactive nitrogen species generators in male versus fema

99 Oxidative damage by reactive nitrogen species has been implicated in the pat

100 However, the ability of EPO to generate reactive nitrogen species has not yet been reported.

101 compounds indicate that tyrosyl radical and reactive nitrogen species have attacked tyrosine residue

102 Since MPO and MPO-derived HOCl, as well as reactive nitrogen species, have been implicated in the p

103 a hydroxylation, while biologically produced reactive nitrogen species (hydroxylamine (NH(2)OH), nitr

104 To investigate the involvement of reactive nitrogen species in atherogenesis, we quantifie

105 d the hypothesis that increased formation of reactive nitrogen species in biliary cirrhosis causes ni

106 the interplay of reactive oxygen species and reactive nitrogen species in cardiac signaling pathways

107 ng the concentrations of reactive oxygen and reactive nitrogen species in cells, tissues, and biologi

108 le nitric oxide synthase and accumulation of reactive nitrogen species in lung tissue and bronchoalve

109 nt control over the form and availability of reactive nitrogen species in marine environments.

110 The predominant reactive nitrogen species in mitochondria are nitric oxi

111 e BRB by a mechanism involving the action of reactive nitrogen species in promoting expression of VEG

112 ablished whether HDL proteins are damaged by reactive nitrogen species in the circulation or artery w

113 , these data indicate a significant role for reactive nitrogen species in the insulin exocytosis mech

114 Urea is one of the most essential reactive nitrogen species in the nitrogen cycle and play

115 the important contribution of photoproduced reactive nitrogen species in vanillin phototransformatio

116 S) renders nonreplicating Mtb susceptible to reactive nitrogen species in vitro and unable to survive

117 rong evidence that myeloperoxidase generates reactive nitrogen species in vivo and that it operates i

118 , a global marker of protein modification by reactive nitrogen species, in proteins recovered from br

119 Des-nitro metabolite formation generated reactive nitrogen species, including nitric oxide (NO),

120 e and susceptible to the formation of highly reactive nitrogen species, including nitrogen dioxide, d

121 e/nitrative damage arising from formation of reactive nitrogen species, including peroxynitrite.

122 The addition of the reactive nitrogen species increases the disinfection eff

123 vel mechanism by which products generated by reactive nitrogen species induce dopaminergic neuron dea

124 em revealed that reactive oxygen species and reactive nitrogen species inhibit SufB extein ligation b

125 binding of nitrite to heme Fe, and that the reactive nitrogen species involved derives from nitrous

126 that the E. coli transcriptional response to reactive nitrogen species is a composite response mediat

127 thological conditions in which production of reactive nitrogen species is increased and that antinitr

128 NO), which has recently been identified as a reactive nitrogen species, is a challenging task.

129 c cells (i.e., reactive oxygen species [ROS]/reactive nitrogen species, lysosome, iron uptake, and tr

130 Host reactive nitrogen species maintain intracellular Salmone

131 ived radical species formed by reaction with reactive nitrogen species may account for inhibition of

132 Production of reactive nitrogen species may be one important pathway,

133 We hypothesized that NO or derivative reactive nitrogen species may generate adducts of tyrosi

134 Reactive nitrogen species may play a mechanistic role in

135 real time, although peroxynitrite and other reactive nitrogen species may potentially contribute to

136 ted from macrophages may occur chemically by reactive nitrogen species-mediated protein modification,

137 ould lead to the sustained production of the reactive nitrogen species nitric oxide and peroxynitrite

138 In the presence of oxygen, NO and NO-related reactive nitrogen species nitrosate 4,5-diaminofluoresce

139 ote the release of atmospherically important reactive nitrogen species (NO(y)), such as HONO, via mec

140 determine the effects of reactive oxygen and reactive nitrogen species on DDAH activity demonstrated

141 a powerful tool for exploring the impact of reactive nitrogen species on oxidative reactions in vivo

142 attributable solely to chemical quenching of reactive nitrogen species or reduction in mutation frequ

143 dase-generated reactive brominating species, reactive nitrogen species, or tyrosyl radicals in vitro

144 itrated at tyrosine residues in vitro by the reactive nitrogen species peroxynitrite and nitrogen dio

145 Among reactive nitrogen species, peroxynitrite is the most pow

146 Reactive intermediates such as reactive nitrogen species play essential roles in the ce

147 Reactive oxygen species and reactive nitrogen species play important roles during im

148 uni viability was measured after exposure to reactive nitrogen species produced biochemically as acid

149 Reactive oxygen species and reactive nitrogen species produced by epithelial and inf

150 lmonella enterica serovar Typhimurium to the reactive nitrogen species produced by inducible nitric o

151 In low stenosis areas, diabetes enhanced reactive nitrogen species production, as evidenced by in

152 n under pathological conditions encompassing reactive nitrogen species production.

153 ) and several downstream effects of ROS/RNS (reactive nitrogen species) production such as inhibiting

154 ions, biomolecules, reactive oxygen species, reactive nitrogen species, redox potential, chemical rea

155 following haemorrhagic shock is mediated by reactive nitrogen species released within the airspaces

156 Blocking the generation of reactive nitrogen species relocated CD8(+) T cells into

157 tional regulators of the E. coli response to reactive nitrogen species remain to be identified becaus

158 tyrosine, markers of lipid peroxidation, and reactive nitrogen species, respectively, and an antibody

159 t, aniA, norB, and dnrN (encoding a putative reactive nitrogen species response protein) were express

160 acellular electrons by causing intracellular reactive nitrogen species (RNS) accumulation, suppressin

161 duction of reactive oxygen species (ROS) and reactive nitrogen species (RNS) and subsequent oxidative

162 Reactive Nitrogen Species (RNS) are a group of bacterici

163 stimulated reactive oxygen species (ROS) and reactive nitrogen species (RNS) are essential activators

164 Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are produced, in part, f

165 hort-lived reactive oxygen species (ROS) and reactive nitrogen species (RNS) are strongly coupled in

166 e of substantially inhibiting PDHC and OGDC: reactive nitrogen species (RNS) can covalently modify th

167 d by inducible nitric oxide synthase (iNOS), reactive nitrogen species (RNS) can kill Mycobacterium t

168 Higher AMP/ATP ratios and increased reactive nitrogen species (RNS) can lead to AMPK activat

169 ransplantational hepatic iNOS expression and reactive nitrogen species (RNS) formation (nitrite and n

170 Cl(2), N(2)O, and DO profiles indicated that reactive nitrogen species (RNS) formed during NHCl(2) de

171 Reactive nitrogen species (RNS) function as powerful ant

172 oQ sensor kinase lessens the cytotoxicity of reactive nitrogen species (RNS) generated by inducible n

173 ibutes to the resistance of this pathogen to reactive nitrogen species (RNS) generated from the nitri

174 damine-123 was used to quantify in real time reactive nitrogen species (RNS) generation by renal tubu

175 study, the effects of 1 mM sodium nitrite, a reactive nitrogen species (RNS) generator, and 0.5 mM pa

176 Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been implicated in

177 induced by reactive oxygen species (ROS) and reactive nitrogen species (RNS) in aerobic metabolism.

178 its surface and the subsequent formation of reactive nitrogen species (RNS) in doses that could be m

179 es produce reactive oxygen species (ROS) and reactive nitrogen species (RNS) in response to bacterial

180 ma composition with a particular emphasis on reactive nitrogen species (RNS) including nitrogen dioxi

181 that damage to the ETC following exposure to reactive nitrogen species (RNS) is less in co-cultured n

182 Elevated levels of nitric oxide (NO) and reactive nitrogen species (RNS) may link inflammation to

183 ants have increased airway concentrations of reactive nitrogen species (RNS) metabolites.

184 consistent with the idea that GSH scavenges reactive nitrogen species (RNS) other than NO.

185 Reactive nitrogen species (RNS) play an essential role i

186 that both reactive oxygen species (ROS) and reactive nitrogen species (RNS) play important roles in

187 ter persister formation in macrophages, host reactive nitrogen species (RNS) produced in response to

188 (LTB(4)), reactive oxygen species (ROS), and reactive nitrogen species (RNS) production is unclear, a

189 Superoxide and ROS/reactive nitrogen species (RNS) productions were determi

190 roducts of the reactive oxygen species (ROS)/reactive nitrogen species (RNS) reactions, particularly

191 Nitrogen dioxide is a highly toxic reactive nitrogen species (RNS) recently discovered as a

192 The addition of a reactive nitrogen species (RNS) scavenger, that is, 2-4-

193 ctericidal reactive oxygen species (ROS) and reactive nitrogen species (RNS) than those recruited to

194 nt of both reactive oxygen species (ROS) and reactive nitrogen species (RNS) that act to further incr

195 a burgdorferi encounters potentially harmful reactive nitrogen species (RNS) throughout its infective

196 that BCKDC can be substantially inhibited by reactive nitrogen species (RNS) via a mechanism similar

197 homatis genital infection, the production of reactive nitrogen species (RNS) via iNOS protects a sign

198 generating reactive oxygen species (ROS) and reactive nitrogen species (RNS) via radiolysis of water.

199 ty against reactive oxygen species (ROS) and reactive nitrogen species (RNS) was determined.

200 ts against reactive oxygen species (ROS) and reactive nitrogen species (RNS) was evaluated by in vitr

201 xynitrite ((-)OON horizontal lineO, PN) is a reactive nitrogen species (RNS) which can effect deleter

202 on and exposure to reactive oxygen (ROS) and reactive nitrogen species (RNS), allowing them to surviv

203 tion of reactive oxygen species (ROS) and/or reactive nitrogen species (RNS), and antioxidants or ROS

204 eration of reactive oxygen species (ROS) and reactive nitrogen species (RNS), and dopamine release we

205 e a number of reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur spe

206 ecifically reactive oxygen species (ROS) and reactive nitrogen species (RNS), has been proposed as an

207 Reactive nitrogen species (RNS), in particular nitric ox

208 r mechanism, this leads to the generation of reactive nitrogen species (RNS), including peroxynitrite

209 s, such as reactive oxygen species (ROS) and reactive nitrogen species (RNS), promote diseases such a

210 re, we identify mitochondrial superoxide and reactive nitrogen species (RNS), specifically peroxynitr

211 d pancreatic tumors and found that excessive reactive nitrogen species (RNS), such as nitrite, are ge

212 ediated by reactive oxygen species (ROS) and reactive nitrogen species (RNS), which can alter the bio

213 ever, GPX1 exerts an intriguing dual role in reactive nitrogen species (RNS)-related oxidative stress

214 ) leak, which drives increased generation of reactive nitrogen species (RNS).

215 it survives in the host despite exposure to reactive nitrogen species (RNS).

216 AMPK in parallel with increased detection of reactive nitrogen species (RNS).

217 rotyrosine, a stable biomarker of NO-induced reactive nitrogen species (RNS).

218 ntributes to the resistance of Salmonella to reactive nitrogen species (RNS).

219 duction of reactive oxygen species (ROS) and reactive nitrogen species (RNS).

220 duction of reactive oxygen species (ROS) and reactive nitrogen species (RNS).

221 selectivity of the reaction of Cys(203) with reactive nitrogen species (RNS).

222 -generated reactive oxygen species (ROS) and reactive nitrogen species (RNS).

223 somes/lysosomes by nitric oxide (NO)-derived reactive nitrogen species (RNSs) and/or superoxide-deriv

224 he generation of reactive oxygen species and reactive nitrogen species (ROS and RNS).

225 Reactive oxygen and reactive nitrogen species (ROS, RNS) formed in the inner

226 -redox-potential reactive oxygen species and reactive nitrogen species (ROS/RNS), generated by NADPH

227 as the generation of reactive oxygen species/reactive nitrogen species (ROS/RNS), have not been fully

228 antioxidant through reactive oxygen species/reactive nitrogen species scavenging, or 3) post-transla

229 ylori strains to reactive oxygen species and reactive nitrogen species, stressors found in their natu

230 Reactive nitrogen species such as nitric oxide, peroxyni

231 high levels of nitric oxide (NO) and related reactive nitrogen species such as nitroxyl and peroxynit

232 vations strongly support the hypothesis that reactive nitrogen species such as ONOO- form in the huma

233 To explore the role of reactive nitrogen species such as ONOO- in the pathogene

234 nclude hydroxyl radical, tyrosyl radical, or reactive nitrogen species such as peroxynitrite.

235 ls in the hydrogen peroxide solution and the reactive nitrogen species supplied by the plasma effluen

236 Because nitric oxide (NO) and derived reactive nitrogen species target zinc ions and cysteine

237 ide inactivation and generation of cytotoxic reactive nitrogen species that attack DNA, lipids, and p

238 amage induced by peroxynitrite, an important reactive nitrogen species that causes a diversity of pat

239 was concluded that GlbN protects cells from reactive nitrogen species that could be encountered natu

240 Peroxynitrite and nitrogen dioxide (NO2) are reactive nitrogen species that have been implicated as c

241 rophages produce reactive oxygen species and reactive nitrogen species that have potent antimicrobial

242 Nitrites generate reactive nitrogen species that may cause damage to the l

243 for iNOS overexpression and the increase in reactive nitrogen species that promote damage in dystrop

244 on of light also results in the formation of reactive nitrogen species that transform organic contami

245 e intense interest in pathways that generate reactive nitrogen species, the physiologically relevant

246 asbestos inhalation induces the formation of reactive nitrogen species, three groups of rats were exp

247 for therapies capitalizing on the ability of reactive nitrogen species to induce autophagy-mediated c

248 we investigated the ability of nitric oxide/reactive nitrogen species to kill two strains of C. jeju

249 Here we report that generation of reactive nitrogen species upon lipopolysacharide/interfe

250 atment of NAC solution creates predominantly reactive nitrogen species versus reactive oxygen species

251 Activation of iNOS to produce reactive nitrogen species was not necessary for vaccine

252 genes involved in the protective response to reactive nitrogen species were up-regulated in the bubo.

253 roxide (H2O2) and nitrite (NO2-) to generate reactive nitrogen species which convert tyrosine to 3-ni

254 has been shown to mediate the generation of reactive nitrogen species, which have antimicrobial acti

255 These "reactive nitrogen species" will, in turn, mediate both o

256 Azanone (HNO) is a reactive nitrogen species with pronounced biological act

257 coccus aureus endures bursts of host-derived reactive nitrogen species, yet the molecular defenses th