ライフサイエンスコーパス: redundancy

1 d a quantitative measure of their functional redundancy.

2 cture, 2) enzyme promiscuity, and 3) network redundancy.

3 ng signaling pathways, leading to functional redundancy.

4 evenness, leading to declines in functional redundancy.

5 null embryos, providing in vivo evidence of redundancy.

6 t, prompting efforts to unravel this seeming redundancy.

7 s' initial trait structure and initial trait redundancy.

8 ological features that favor high functional redundancy.

9 nts despite inherent physiological noise and redundancy.

10 e to completely exploit much of the inherent redundancy.

11 initial activation of these inputs, removing redundancy.

12 elective constraints consistent with greater redundancy.

13 ion factor paralogs with apparent functional redundancy.

14 subtypes and no indication of comprehensive redundancy.

15 effector proteins comprising high functional redundancy.

16 to use such interfaces involves dealing with redundancy.

17 for mitosis, demonstrating their functional redundancy.

18 utagenesis is highly inefficient due to gene redundancy.

19 tribute to enhancing GrC diversification and redundancy.

20 same set of GPCRs, which implies functional redundancy.

21 e primary and secondary CESAs, and some CESA redundancy.

22 omputational handicap and reduce information redundancy.

23 mains with phenotypes masked by lethality or redundancy.

24 on largely supports the notion of functional redundancy.

25 nzymes and two MutMs, suggesting substantial redundancy.

26 PC in each pathology, considering functional redundancy.

27 dual hepatic transcription factor via mutual redundancy.

28 ological features that favor high functional redundancy.

29 g an ecological property known as functional redundancy.

30 e over 70 MRPs and suggest little functional redundancy.

31 ers phenotypes normally masked by functional redundancy.

32 artifacts, chemical contaminants, and signal redundancies.

33 ampal output area CA1 are thought to exhibit redundancy across cortical and hippocampal inputs.

34 n addition to structural diversity to define redundancy across the compound sets.

35 Functional redundancy among factors and pathways underlies the impo

36 ion that was previously hidden by functional redundancy among homoeologs.

37 fied new targets of non-HLA Abs, with little redundancy among individuals.

38 These findings identify functional redundancy among Kit-dependent hematopoietic lineages an

39 Functional redundancy among the three mtACPs was indicated by the e

40 However, redundancy among the two mammalian family members and th

41 Both environmental gradient and redundancy analyses revealed significant association bet

42 Redundancy analyses revealed that in the summer, urban a

43 Redundancy analysis (RDA) indicated that humidity, tempe

44 A) was used to characterize trait variation, redundancy analysis (RDA) to reveal climate effects, and

45 In addition, redundancy analysis indicated that the Fusarium genera w

46 Primary dimensions in distance-based redundancy analysis of clinical chemistries explained 18

47 w how the use of phylogenetic distance based redundancy analysis provides ecological interpretation o

48 ity, DO, and other variables (regression and redundancy analysis r(2) = 0.68-0.82), displaying predic

49 Redundancy analysis revealed that community variation of

50 Redundancy analysis showed significant correlations betw

51 A distance-based redundancy analysis was used to show that DO perturbatio

52 ygous for predicted LoF alleles reveals both redundancies and advantages of such deficiencies for hum

53 ucture of domesticated barley and points out redundancies and coverage gaps in one of the world's maj

54 manner will unmask the effects of homoeolog redundancy and allow the hidden potential of this polypl

55 m ticks bind multiple chemokines to overcome redundancy and are effective in several preclinical dise

56 family member has been limited due to their redundancy and broad effects on multiple lineages of cel

57 e the differences among these sites based on redundancy and cluster analyses.

58 nges are expected to decrease the functional redundancy and complementarity of pollinator assemblages

59 Structural redundancy and directional network stiffening ensure rob

60 ality sensing to improve precision by adding redundancy and encoding features, thus increasing measur

61 ere has the potential to increase functional redundancy and enhance the ability of soil communities t

62 Chemokine redundancy and ensuing network robustness has frustrated

63 round metabolism offers, providing metabolic redundancy and flexibility which allow for the best use

64 re, we briefly review the general concept of redundancy and focus on the evolutionary importance of r

65 s resistance, among host genotypes may offer redundancy and generally limit the invasion potential of

66 We reveal that plant VOC redundancy and herbivore specialization can be explained

67 Because of partial redundancy and high endogenous expression of PP2A holoen

68 ferent co-existing taxa supported functional redundancy and imparted process stability to these react

69 nd cooling elements to regulate temperature, redundancy and incoherence in regulation generally sugge

70 ngs show that high TF motif density provides redundancy and increases promoter activity at the expens

71 In conclusion, Kv3 channels exhibit both redundancy and Kv3.3 dominance between the brainstem nuc

72 ilar objects during a beamtime leads to data redundancy and long acquisition times.

73 To minimise redundancy and maximise discovery, we undertook a multip

74 issection of actin molecular function due to redundancy and neofunctionalization.

75 Functional redundancy and phase variation might explain the lack of

76 tribute to regulatory plasticity by inducing redundancy and potentiating genetic drift locally while

77 This feature is often explained in terms of redundancy and regulatory flexibility, but it has remain

78 Phosphoproteomics suffers from lack of redundancy and statistical power for generating high con

79 Using genetic redundancy and structure-function analyses to truncate C

80 ion method was implemented to reduce feature redundancy and subset selection.

81 We developed GOMCL to reduce redundancy and summarize lists of GO terms effectively a

82 analysis and highlights the consequences of redundancy and synergy during information transmission,

83 e altered the resource availability, trophic redundancy and the flow of energy to other trophic level

84 rved throughout evolution, together with the redundancy and tissue specificity of their components, p

85 eater integration across theories (to reduce redundancy) and greater emphasis on the circumstances un

86 t file, estimates of genome completeness and redundancy, and a phylogenomic tree based on a specified

87 justing the neuron's dynamic range, reducing redundancy, and facilitating probabilistic inference.

88 as distinct entries in databases causes data redundancy, and misleads downstream analysis.

89 h phenotype dominated by MAD, marked leaflet redundancy, and repolarization abnormalities.

90 esis bias, storage physical density, logical redundancy, and sequencing redundancy, providing insight

91 tly associated with presence of MAD, leaflet redundancy, and T-wave inversion/ST-segment depression (

92 l species can achieve a degree of functional redundancy, and that their compensatory herbivory may pl

93 Further redundancies are suggested for individual tricalbin prot

94 , whereas PCs that potentially could provide redundancy are expressed at considerably lower levels.

95 e greatest mutualist richness and functional redundancy are nearly two times more likely to survive e

96 me duplication may have occurred due to gene redundancy (as functional copies of MSH5A, MSH4A, and MS

97 Several levels of functional redundancy at different scales of the bacterial metacomm

98 onfidence in existing measures of pollinator redundancy at the community level using visitation data,

99 as the leave-one-out differences in average redundancy, average number of edges in the step-1 ego ne

100 tistical and computational challenges due to redundancy, badly behaved data and noise.

101 bvious phenotype, possibly due to functional redundancy, because Sdr16c5 and Sdr16c6 exhibit an overl

102 Simulations predict redundancies between lower level sibling SCPs within eac

103 of stress-induced anxiety and the functional redundancy between AEA and 2-AG signaling in the modulat

104 s) to further study the extent of functional redundancy between both genes regarding two processes: m

105 radation, and have illuminated the extent of redundancy between different ER-phagy 'pathways' in remo

106 s, we have implemented two methods to reduce redundancy between enriched gene sets.

107 een antigens driving population dynamics, or redundancy between functionally similar accessory ABTs,

108 across individual time steps, and we compute redundancy between genes by using a dynamical time warpi

109 Although redundancy between H2BE18 and H2BE19 ADP-ribosylation is

110 Functional redundancy between H3K27 demethylase activities of KDM6A

111 s model to estimate the degree of functional redundancy between homeoallelic loci and a statistical f

112 Partial functional redundancy between homeologous genes should result in a

113 of dnapkcs-exo1- cells to PARPi, indicating redundancy between nucleases that initiate HR can drive

114 the largest role, but there is also partial redundancy between receptors.

115 early diverging lineages and the functional redundancy between species increased multifunctionality.

116 -objective control models demonstrated clear redundancy between stepping variables, but could not rep

117 ity are difficult to decipher as a result of redundancy between the family members.

118 ndings demonstrate that there is a degree of redundancy between the PRMT5 and PRMT1 pathways, even th

119 Moreover, we show that there is functional redundancy between the two type II receptors as well as

120 tes were excluded, indicating low functional redundancy between these groups.

121 orrelations and, in some cases, evidence for redundancy, between Implicit Association Tests (IATs) me

122 Consistent with this redundancy, both LjEin2a and LjEin2b are required for ne

123 that MLL1/MLL2 collaboration is not through redundancy, but regulation of distinct pathways.

124 ncrease model complexity, and reduce network redundancy by focusing on relevant anatomy.

125 iseases, and, more generally, that metabolic redundancies can be exploited for selective targeting of

126 This work reveals how context-dependent redundancies can shape tumor-type specific mutation patt

127 of the plant TGN and suggest that functional redundancy can be achieved through parallelization of mo

128 Genetic redundancy can be exploited to identify therapeutic targ

129 Environmental dependency and genetic redundancy can explain the maintenance of atavistic trai

130 truly matters amid a complex system full of redundancy can now be identified.

131 Here, through a combination of a redundancy-circumventing genetic screen and biochemical

132 ts that high species richness and functional redundancy could promote mutualism persistence in comple

133 data based on maximum relevance and minimum redundancy criteria.

134 e benefits of a mass balance approach due to redundancy, data consistency, and transparency for optim

135 dimensionality (reflecting less information redundancy) during task states, suggesting that decrease

136 We discuss the challenges in determining redundancy empirically, with published experimental exam

137 We learn that high structural redundancy enables reduced total cost and faster recover

138 ructure and function, it is likely that some redundancy exists between the two isoforms, meaning that

139 account of efficiency: In certain contexts, redundancy facilitates communication (e.g., when the col

140 We assembled two redundancy-filtered reference protein catalogs, 2 billio

141 iological roles and the extent of functional redundancy following embryo implantation.

142 %-64%) observed is likely enabled by genomic redundancy following polyploidy.

143 Although eukaryotes possess a number of redundancies for initiating and completing repair of mis

144 Our data further indicate limited redundancy for NSD family members in HPV-negative HNSCCs

145 We also uncover functional redundancy for somatic embryogenesis among other Arabido

146 This two-tier functional redundancy for translation quality control breaks down d

147 a require careful calibration, adequate data redundancy from a 2D array of 2048 elements and a paraxi

148 y local network damage, analogous to the way redundancy guarantees the large-scale function of vascul

149 Genetic redundancy has been defined in many different ways at di

150 Such functional redundancy has been hypothesized to underlie the stabili

151 information significantly better compared to redundancy hubs or heterogeneous sub-populations.

152 y across cortical layers to form synergy and redundancy hubs.

153 Urban food webs also had lower trophic redundancy (i.e. fewer species at each trophic level) an

154 genetic interactions can dissect functional redundancies in cellular networks.

155 tomic and genomic data to evaluate potential redundancies in cork triterpenoid biosynthesis.

156 e assumptions are often violated due to both redundancies in functional descriptions and biological f

157 The lack of redundancies in ribonucleotide repair in archaea perhaps

158 pression facilitates tumor resistance due to redundancies in the phosphatidylinositol-3'-kinase/prote

159 rticle explores the functional diversity and redundancy in a bacterial metacommunity constituted of t

160 The level of genetic redundancy in a single-celled organism may thus reflect

161 iggers MST2 autophosphorylation and possible redundancy in activation.

162 mputation accuracy, model incompleteness and redundancy in different gene sets.

163 The redundancy in E2's induction of MMP9 and MMP13 suggests

164 GM-CSF and IL-5 stimulation demonstrated redundancy in eosinophil gene expression.

165 We define RNL redundancy in ETI conferred by some TNLs and in basal re

166 te the use of the C-score metric to quantify redundancy in evolution studies.

167 her understanding the prevalence and role of redundancy in evolution.

168 mine the capabilities afforded by functional redundancy in fatty acid synthesis.

169 gradely labelled colonic neurons, suggesting redundancy in function.

170 rgistic defects in RNA packaging, suggesting redundancy in Gag-RNA interactions and a requirement for

171 lation could overcome the signalling pathway redundancy in GBM and, hence, promote tumour cell death.

172 Additionally, there appears to be functional redundancy in genera of CCRA providing cues to abalone,

173 measure, co-information, quantifies the net redundancy in global and local control.

174 ssect complex biological systems and genetic redundancy in microbial systems.

175 covarying acoustic attributes, resulting in redundancy in neural coding.

176 diploids, suggesting that increased genomic redundancy in polyploids does not necessarily translate

177 n which a like-suppresses-like motif reduces redundancy in population activity and may assist with in

178 -based data formats do not fully exploit the redundancy in population sequencing nor take advantage o

179 We contrast the implicit assumptions of redundancy in quantitative versus population genetic mod

180 sgRNAs) were designed per gene to facilitate redundancy in rendering the genes inactive, thereby redu

181 analysis has shown the absence of functional redundancy in resistance to SCN.

182 lication of model restructuration, to reduce redundancy in rule-derived equations.

183 . japonicus While mutant analysis identified redundancy in several biosynthesis families, we found th

184 bly in vivo reveal structural and functional redundancy in Spc42 assembly.

185 and focus on the evolutionary importance of redundancy in terms of the number of genotypes that give

186 gime, mechanical cooperativity sets in via a redundancy in the assignment of constraints, and the deg

187 A percolation transition in the redundancy in the constraints as a function of constrain

188 Synonymous codons provide redundancy in the genetic code that influences translati

189 egulatory module that takes advantage of the redundancy in the genetic code to modulate protein expre

190 rocesses that create and maintain functional redundancy in the human microbiome and contribute to its

191 ere, we investigate the basis for functional redundancy in the human microbiome by analyzing its geno

192 ringently required, likely due to functional redundancy in the latter.

193 Second, there may be high functional redundancy in the methanogens with regard to methane pro

194 g in one dimension and increasing structural redundancy in the other.

195 With consideration of structural redundancy in the PDB, tendencies toward specific molecu

196 Specifically, we include redundancy in the physical sensor design to alleviate th

197 tratified RGC, indicating that there is more redundancy in the retinal color code than previously app

198 er continues unabated, suggesting functional redundancy in the traits examined.

199 strates that EEEV exhibits a unique level of redundancy in the use of host factors in RNA replication

200 ncludes seven endoproteases with significant redundancy in their cleavage activity.

201 e powerful tools for overcoming the issue of redundancy in these gene families and will undoubtedly a

202 Furthermore, the redundancy in this collection of plants allowed for the

203 in macrophages and, in some cases, leads to redundancy in this host cell type.

204 Pseudomonas syringae, indicating functional redundancy in this large gene family.

205 Here we show that redundancy in this system is provided by a protonated Sc

206 ular Cu homeostasis and suggests a potential redundancy in this system, where hGrx1 has the potential

207 North American EEEV exhibits a high level of redundancy in using host factors in replication complex

208 They play key roles, often in redundancy, in multiple developmental pathways, includin

209 We demonstrate that this redundancy is absent in the murine Anp32 orthologues; mu

210 Moreover, redundancy is neither necessary nor sufficient to make p

211 nicate efficiently, yet the tendency towards redundancy is said to increase in older age.

212 The origin of functional redundancy is still elusive.

213 Because of complex feedback interactions and redundancy, it has been difficult to define the portion

214 e duplicate genes may retain some functional redundancy, it is clear that to survive selection they c

215 eory predicts that key traits and high trait redundancy-large species richness and abundance supporti

216 detect such covariation and adapt to reduce redundancy, leading to more efficient neural coding.

217 To reduce such redundancy, many tools have been developed to recognize

218 eature selection procedures based on Minimum Redundancy Maximum Relevance (mRMR) and variance prior t

219 We propose a temporal minimum redundancy - maximum relevance (TMRMR) feature selection

220 s the coordination of muscles using pairwise redundancy measured through interaction information.

221 male sex, bileaflet prolapse, marked leaflet redundancy, mitral annulus disjunction (MAD), a larger l

222 The maximum relevance minimum redundancy (mRMR) algorithm and the least absolute shrin

223 meostasis in the majority of contexts due to redundancy of adult function with E2F1 and E2F2.

224 may share factors to enhance the functional redundancy of both.

225 stion(9,10), which may be accentuated by the redundancy of CD28 and CD3zeta signaling(11,12) as well

226 equired for protection and reveal unexpected redundancy of common beta chain-dependent cytokines prev

227 ensive corticoreticular convergence provides redundancy of control, which may allow the cortex to con

228 taken here overcomes a problematic molecular redundancy of CspC and CspE that likely explains why the

229 of metabolic controls-produced when gains in redundancy of dietary inputs coincide with increased bra

230 an effect on the level of repeatability and redundancy of features, emphasizing the importance of bo

231 Supporting redundancy of function by the two cytokines, CA-MSC indu

232 ditional knockout mice, we show that genetic redundancy of Gata3 with paralog Gata2 in trophoblast pr

233 on anatomical pattern, also led to increased redundancy of GrC input combinations.

234 frequently is complicated by the functional redundancy of homologous genes.

235 ts of CA-MSC paracrine LIF signaling and the redundancy of IL6 and LIF in activating ovarian cancer S

236 A large proportion of the complexity and redundancy of LC-MS metabolomics data comes from adduct

237 our results suggest functional divergence or redundancy of MCTP members in Arabidopsis and provide a

238 natorial TIMP-deficient mice demonstrate the redundancy of metalloprotease inhibitor function in embr

239 echanisms involved, routes of dissemination, redundancy of molecular pathways that can be utilized, a

240 To reduce statistical redundancy of natural inputs and increase the sparseness

241 due to promiscuity of complement factors and redundancy of pathways, it is still a major challenge.

242 The resulting redundancy of RITS may have eased the selection pressure

243 ics of communities as well as the functional redundancy of taxonomic groups.

244 These findings indicate functional redundancy of the B. pseudomallei phospholipases in viru

245 However, functional identity and functional redundancy of the community as a whole remain unchanged.

246 r the frontoparietal cortical area where the redundancy of the extension wire is placed subcutaneousl

247 l infection, illustrating the robustness and redundancy of the innate antiviral defenses in fish.

248 Particularly, we demonstrate redundancy of the Pol alpha-primase DNA polymerase activ

249 ore than 180 million years, the reduction of redundancy of the polyploid genome seems to have been re

250 antation (FMT), finding that high functional redundancy of the recipient's pre-FMT microbiota raises

251 clinic have failed thus far, possibly due to redundancy of the target receptor.

252 h predation and warmer temperatures suggests redundancy of their size-selective effects, meaning that

253 e of any single ZDHHC, suggesting functional redundancy of these enzymes in the IFITM3-mediated antiv

254 ot vice versa, indicating partial functional redundancy of these two closely related isoforms and hig

255 strong structural similarity and functional redundancy of these two enzymes, the mechanisms regulati

256 This 'apparent redundancy' of MDR efflux systems can be understood as a

257 cesses regulated by a hierarchy, rather than redundancy, of effectors.

258 trating the influence of trait structure and redundancy on community sensitivity over large temporal

259 Due to feature redundancy or outliers in samples, using all available d

260 sing from whole-genome duplication-generated redundancy or the capture and movement of gene fragments

261 am and 79 kb downstream) with median 27-fold redundancy per base.

262 Targeting this redundancy provides a vulnerability for tumors carrying

263 We propose that this functional redundancy provides one explanation for the absence of S

264 density, logical redundancy, and sequencing redundancy, providing insights for engineering efficient

265 From this redundancy reduction hypothesis, a theory of retinal col

266 spite their extreme diversity and functional redundancy, respond to disturbances like many macro-ecol

267 Genetic redundancy resulting from whole genome duplication is th

268 In allohexaploid wheat, however, genic redundancy results in rarity of such mutants, with the e

269 ing that the computational advantage of such redundancy should be reflected in differences in how the

270 sation is inversely correlated with enhancer redundancy, suggesting that such compensation may often

271 This functional redundancy suggests that therapeutic targeting of a sing

272 It exploits the redundancy that arises from multiple rounds of PCR ampli

273 s a high degree of functional plasticity and redundancy through myriad mutational pathways.

274 al code could be defined as one that reduces redundancy to communicate as much information as possibl

275 interdependence among closed areas and allow redundancy to develop in some of the areas of the networ

276 ive of unappreciated evolutionary functional redundancy to facilitate angiogenesis and ensure mainten

277 ial transcription factor input, feedback and redundancy to generate cell type-specific levels of dve

278 t that several domains contribute, with some redundancy, to maintenance of the overall RRE shape.

279 they showed phenotypic instability, the high redundancy was lost, and gid1a exhibited dwarfism that w

280 Here, to explore centrin redundancy, we generated Cetn3 (GT/GT) single-knockout a

281 change, while communities with higher trait redundancy were more resistant.

282 This circuit is masked by feedback and redundancy when chemoattractant is used as the input, hi

283 stic value across different time steps, with redundancy, which is calculated by employing dynamical t

284 , coastal food webs have greater interaction redundancy, which may confer robustness to species extin

285 twork of signalling cascades with functional redundancy, which provides them with robust compensatory

286 ear load, providing mechanical isolation and redundancy while allowing spindle fluidity.

287 h G4-forming sequences, and exhibits partial redundancy with an adjacent PARP-binding domain.

288 ate the role of Chk in platelets, functional redundancy with Csk, and the physiological consequences

289 with OsPIP5K1 and shares partial functional redundancy with DWT1 in controlling rice uniformity.

290 , noncanonical) function of the enzyme or to redundancy with EZH1.

291 We postulated that functional redundancy with its closely related family member, lymph

292 029 grown under continuous light, suggesting redundancy with other ELF3 homologs or possibly an alter

293 Based on functional redundancy with similar motifs derived from human picorn

294 Our data found CHH methylation to act in redundancy with symmetric methylation in silencing trans

295 (OADH) remains obscure due to its catalytic redundancy with the ubiquitous OGDH-encoded 2-oxoglutara

296 c severity over males (MKOs), due to partial redundancy with UTY, a Y-chromosome demethylase-dead hom

297 sed to characterize functional diversity and redundancy within (alpha), between (beta) and across (ga

298 Our results suggest interesting patterns of redundancy within subclass 1 SnRK2 protein kinases, with

299 We take advantage of siderophore redundancy within the non-pathogenic mycobacterial model

300 Due to genetic redundancy within this system, the carbohydrate specific