ライフサイエンスコーパス: refractive error

1 nal misregistration vs strabismus vs optical/refractive error).

2 on due to the fact that myopia is a negative refractive error.

3 ified 336 novel genetic loci associated with refractive error.

4 al diameter, vertical cup-to-disc ratio, and refractive error.

5 8.2 million people had VI due to uncorrected refractive error.

6 and 16.4 million with VI due to uncorrected refractive error.

7 so involved in the development of myopia and refractive error.

8 ns exchange was successful in correcting the refractive error.

9 K1, ARID2-SNAT1 and SLC14A2) associated with refractive error.

10 s prevalence being attributed to uncorrected refractive error.

11 long ALs were within +/-1 D of the predicted refractive error.

12 opic child using a simple, single measure of refractive error.

13 A total of 41 children had high refractive error.

14 visual impairment secondary to a correctable refractive error.

15 tter average best-corrected acuity and lower refractive error.

16 h as visual impairment, strabismus, or major refractive error.

17 correct for the spherical equivalent of the refractive error.

18 significantly overrepresented in relation to refractive error.

19 o 17 years with no ocular abnormality except refractive error.

20 ng for age, optic disc diameter, gender, and refractive error.

21 eans of large genetic association studies of refractive error.

22 deling correlated to the preoperative myopic refractive error.

23 58-12.96) were significantly associated with refractive error.

24 was attributable to cataract and uncorrected refractive error.

25 red noise-on mean spherical equivalent (MSE) refractive error.

26 AMD was caused by a 1-diopter (D) change in refractive error.

27 potential influences of viewing behaviors on refractive error.

28 eridians were used to calculate the intended refractive error.

29 s of intraocular pressure, axial length, and refractive error.

30 ment, axial length, and spherical equivalent refractive error.

31 ted macular degeneration (AMD), glaucoma and refractive error.

32 d they cannot support users with uncorrected refractive errors.

33 most frequently used options for correcting refractive errors.

34 improves visual acuity and reduces residual refractive errors.

35 igher among those with VI due to uncorrected refractive errors.

36 udy were conjunctivitis, ocular injuries and refractive errors.

37 mpliance with spectacle use in children with refractive errors.

38 are now available to treat a wider range of refractive errors.

39 visual performance of uncorrected (residual) refractive errors.

40 nctivitis (35%), then ocular trauma (11.8%), refractive error (11.4%) and trachoma (7.6%).

41 llion]), the leading causes were uncorrected refractive error (116.3 million [49.4 million to 202.1 m

42 were female; mean [SD] spherical equivalent refractive error, -2.39 [1.00] D).

43 identified 124 systematic reviews related to refractive error; 39 met our eligibility criteria, of wh

44 s found in 119 children, and the causes were refractive errors (47.1%), keratitis/corneal opacity (16

45 hildhood-onset nyctalopia, myopia (mean [SD] refractive error, -6.71 [-4.22]), and nystagmus.

46 ading causes of vision loss were uncorrected refractive error (60.8%), cataract (20.1%), and diabetic

47 ading causes of vision loss were uncorrected refractive error (61.3%), cataract (13.2%), and age-rela

48 agmus (14%), amblyopia (24%) and uncorrected refractive error (62%).

49 The most prevalent eye diseases were refractive error (63.2%), conjunctivitis (17.1%), visual

50 [3.4 million to 28.7 million]), uncorrected refractive error (7.4 million [2.4 million to 14.8 milli

51 control group comprised 125 persons without refractive error (79 girls and 46 boys).

52 deling confirmed both traits were heritable (refractive error 85%, intelligence 47%) and the genetic

53 le retinal cell type and have a high risk of refractive errors, a study investigating the affected ce

54 ed information on potential risk factors for refractive error across the life course, but ophthalmic

55 rious steps and methods in managing residual refractive error after laser in situ keratomileusis and

56 epths, thicker lenses, and higher degrees of refractive errors (all P < .001) than those of the full-

57 The high prevalence of refractive error, allergic conjunctivitis, visual impair

58 Refractive error alone accounted for 68.9% of childhood

59 rmination of the proportion of children with refractive errors, amblyopia, and/or strabismus.

60 l symptoms and the association of those with refractive errors among Thangka artists.

61 nding about the interactions among hyperopic refractive error and accommodative and binocular functio

62 ere cataract (19.7%), corneal scars (15.7%), refractive error and amblyopia (12.1%), optic atrophy (6

63 Cataract corneal opacities, refractive error and amblyopia, globe damage due to trau

64 stently reported strong associations between refractive error and AMD are likely to be the result of

65 the assumption that the relationship between refractive error and AMD risk is linear.

66 However, the negative association between refractive error and an increase in height was only pres

67 lues as well as their correlations with age, refractive error and axial length.

68 (OCT) and to perform correlations with age, refractive error and axial length.

69 Refractive error and binocular vision assessment, integr

70 ading causes of vision loss were uncorrected refractive error and cataract, which are readily treatab

71 = 0.01); independent of the effects of age, refractive error and disc area (p < 0.05).

72 These data suggest that vision screening for refractive error and early eye disease may reduce or pre

73 The phenotypic correlation between refractive error and intelligence was -0.116 (p < 0.01)

74 previous genome-wide association studies of refractive error and intelligence.

75 We sought to determine the association of refractive error and its associated determinants (axial

76 was to assess the prevalence of uncorrected refractive error and its associated factors among school

77 ults have identified 39 loci associated with refractive error and myopia.

78 Accurate estimation of refractive error and ocular alignment is critical for id

79 association of height, weight, and BMI with refractive error and ocular biometric measures at age 15

80 To explore a potential relationship with refractive error and ocular structure we performed a lif

81 Vision screening for refractive error and related eye diseases may prevent a

82 r angle measurements and ACV, ACD, spherical refractive error and sex, emerging the ACV as the main d

83 a new abnormality, most commonly significant refractive error and strabismus.

84 These results may enable the prediction of refractive error and the development of personalized myo

85 further investigate the association between refractive error and the likelihood of having diabetic r

86 ere used to estimate the association between refractive error and the prevalence of glaucoma overall

87 assumption of a linear relationship between refractive error and the risk of AMD, myopia and hyperop

88 tists present with significant proportion of refractive error and visual symptoms, especially among f

89 mprised of 112 participants with significant refractive errors and 130 absolutely emmetropic particip

90 diagnosis and early treatment of uncorrected refractive errors and amblyopia.

91 hthalmic examination including assessment of refractive errors and best-corrected visual acuity, biom

92 ive treatments are available for uncorrected refractive errors and cataracts.

93 l acuity, source and type of injury, type of refractive errors and diagnosis were collected and analy

94 e displays can be tailored to correct common refractive errors and provide natural focus cues by dyna

95 Prevalence of refractive errors and school-based differences were anal

96 ditional insight on the proportion of common refractive errors and their association with race/ethnic

97 se cases (69%) arose from simple uncorrected refractive error, and 43000 (25%) from bilateral amblyop

98 ing examination were strabismus, significant refractive error, and eyelid abnormalities (including ec

99 ity (VA), the time course of VA improvement, refractive error, and family history were assessed.

100 or women with visual impairment, uncorrected refractive error, and normal vision were 24.5%, 56.0%, a

101 for men with visual impairment, uncorrected refractive error, and normal vision were 58.7%, 66.5%, a

102 portant to account for age, body mass index, refractive error, and sex when using GCC thickness as a

103 gery), and clinical measures (visual acuity, refractive error, and slitlamp and posterior segment eye

104 visual acuity (CDVA), contrast sensitivity, refractive error, and wavefront aberrometry.

105 including amblyopia, strabismus, significant refractive errors, and unexplained reduced VA.

106 associated with age, smoking status, SBP and refractive error; and ISOS-RPE was additionally associat

107 Most systematic reviews of interventions for refractive error are low methodological quality.

108 Amblyopia, strabismus, and refractive errors are common in young children.

109 Eyeballs having these refractive errors are known to exhibit abnormal eye shap

110 Uncorrected refractive errors are the most common cause of visual im

111 Refractive errors are the product of a mismatch between

112 Uncorrected refractive errors are the second leading cause of worldw

113 ing the 126 genetic variants associated with refractive error as instrumental variables, under the as

114 ay also have treatable strabismus or optical/refractive error as the primary barrier to single vision

115 visual impairment and strabismus, but not on refractive errors, as a whole.

116 cantly with cup-to-disc ratio, axial length, refractive error, astigmatism, and posterior corneal ele

117 hich included age, sex, race, visual acuity, refractive error, astigmatism, cataract status, glaucoma

118 had an MRSE within +/-1.00 D of their target refractive error at 5 years and 67.3% (n = 278/413) were

119 edi and associates may achieve an acceptable refractive error at 7 years of age.

120 The mean refractive error at age 5 years was -2.53 D (95% CI, -4.

121 8) and 2.3% (P = 6.9E-21) of the variance in refractive error at ages 7 and 15, respectively, support

122 in multivariate models: spherical equivalent refractive error at baseline, parental myopia, axial len

123 The median refractive error at the age 5 years visit of the treated

124 Biometric data included values for refractive error, axial length (AL), corneal curvature,

125 Measurement of refractive error, axial length, and complete ophthalmic

126 spectively reviewed with regard to symptoms, refractive error, best corrected visual acuity (BCVA) of

127 constant exotropia) and spherical equivalent refractive error between -6.00 diopters (D) and +1.00 D.

128 llowed by post-VR testing of binocular CDVA, refractive error, binocular eye alignment (strabismus),

129 cuity impairment associated with uncorrected refractive error, cataracts, and age-related macular deg

130 f early vision impairment due to uncorrected refractive error, cataracts, and age-related macular deg

131 impaired visual acuity, such as uncorrected refractive error, cataracts, and dry or wet AMD.

132 odds ratios of visual impairment for various refractive error categories and determined causes by usi

133 al impairment ranged from virtually 0 in all refractive error categories at 55 years of age to 9.5% (

134 or causes of visual impairment for the other refractive error categories were AMD and cataract.

135 omes were safety, predictability, stability, refractive error, CDVA, contrast sensitivity, and higher

136 When adjusted for age and refractive error, central choroidal thickness may not be

137 d a significantly (p < 0.001) lower trend of refractive error change during the follow-up periods.

138 ive Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study was an observational coh

139 Cataract and uncorrected refractive error combined contributed to 55% of blindnes

140 Uncorrected refractive errors contribute enormously to the burden of

141 ar contraindications to LRS include unstable refractive error, corneal ectatic disorders, a history o

142 The outcome measures included visual acuity, refractive error, corneal topography and axial length.

143 s decrease was proportional to the amount of refractive error corrected.

144 post operation, while the combined effect of refractive error correction and optical diameter appeare

145 One refractive error currently attracting significant scient

146 Refractive errors, defined as myopia less than -3 diopte

147 This review defines refractive errors, describes their prevalence, and prese

148 genetic and environmental factors related to refractive error development.

149 eye shape remodeling across the globe during refractive-error development.

150 7.6, P = .03) at baseline, but not with age, refractive error, diagnosis of typical AMD or PCV, numbe

151 Refractive errors did not change across the decade (line

152 were the mean spherical equivalent (MSE) of refractive error (dioptres), axial length (AXL; mm), and

153 nd to be associated with increased change of refractive error during follow-up years.

154 nd to be associated with increased change of refractive error during follow-up years.

155 Refractive error, especially myopia, is the most common

156 Genetic variants for intelligence and refractive error explain some of the reciprocal variance

157 Refractive error, expressed as spherical equivalent (SE)

158 The association with refractive error for the 126 variants was obtained from

159 indicating that it is the commonest type of refractive error found amongst secondary school students

160 Myopia and astigmatism, two common refractive errors frequently co-exist, are affecting vis

161 nd major eye diseases (cataract, uncorrected refractive error, glaucoma, age-related macular degenera

162 pediatric eye care facilities for cataract, refractive errors, glaucoma and rehabilitative services

163 as an axial length less than 20.0 mm and/or refractive error greater than +7.00.

164 The majority of participants (65.1%) among refractive error group (REG) were above the age of 30 ye

165 ination, anisometropia, myopic and hyperopic refractive error (>/= 3 dioptres), astigmatism, birth we

166 MR analysis suggested that refractive error had very limited influence on the risk

167 Of all refractive errors, high myopia has the most severe visua

168 After adjustment for age and refractive error, however, there was no significant diff

169 s and SNP x education interaction effects on refractive error in 40,036 adults from 25 studies of Eur

170 reatment of amblyopia, its risk factors, and refractive error in children aged 6 months to 5 years to

171 ing the affected cell type, causal gene, and refractive error in IRDs may provide insight herein.

172 for amblyopia risk factors or nonamblyogenic refractive error in most studies of test accuracy and we

173 or mechanisms involved in the development of refractive error in populations of European origin.

174 indings provide evidence that development of refractive error in the general population is related to

175 th sex, type of healthcare insurance, or the refractive error in the treated or fellow eye.

176 f hyperopia was defined based on cycloplegic refractive error in the worse eye.

177 trabismus was found in 17.4% (68 of 390) and refractive errors in 29.7% (115 of 387) of the EPT child

178 Correction of refractive errors in the students remained a challenge.

179 Astigmatism (>=1 D) was the most common refractive error, in 13 (40%) and 14 (47%) subjects, res

180 Refractive errors, in particular myopia, are a leading c

181 Refractive errors, in particular myopia, are common in I

182 Treating the components of the refractive error independently, outliers were observed i

183 Visual acuity, refractive error, intraocular pressure, slit lamp examin

184 R(2): IOPg 2.30%, IOPcc 2.26%), followed by refractive error (IOPg 0.60%, IOPcc 1.04%).

185 Residual refractive error is a known complication after both lase

186 the number of people affected by uncorrected refractive error is anticipated to rise to 127.7 million

187 rk, especially among people with uncorrected refractive error is considered a potential source of vis

188 Our results suggest that refractive error is genetically heterogeneous, driven by

189 The refractive error is measured using a Shack-Hartmann wave

190 Uncorrected Refractive Error is one of the leading cause amblyopia t

191 Using a phoropter to measure the refractive error is one of the most commonly used method

192 Refractive error is the main cause of visual impairment

193 The burden of uncorrected refractive errors is high among primary schools children

194 ns that these children will often have large refractive errors later in childhood that may necessitat

195 ase opportunities for integrated research on refractive error leading to development of novel prevent

196 %) had normal distance vision or uncorrected refractive error, less than half (46.1%) used near-visio

197 igher systolic blood pressure, more negative refractive error, lower IOPcc and lower corneal hysteres

198 hree students were identified to have myopic refractive error making the prevalence of 6.5% (95% CI:

199 Thirty-six subjects whose baseline age and refractive error matched with those in the orthokeratolo

200 patients with PPG and 67 eyes of 67 age- and refractive error-matched controls.

201 (rd6) mice suggests hyperopia and associated refractive errors may be amenable to AAV gene therapy.

202 raphic optical elements to perform automatic refractive error measurement and provide a diagnostic pr

203 children (71%) were eligible for cycloplegic refractive error measurements.

204 Prediction error was defined as refractive error minus emmetropia.

205 heral rivalry-type diplopia), 1 (4%) optical/refractive error (monocular diplopia), 2 (8%) mixed reti

206 th and central and peripheral mean spherical refractive error (MSE) were measured at baseline and aft

207 Refractive error (myopia or hyperopia) was significantly

208 0.0001) and greater magnitude of significant refractive errors (myopia, hyperopia, astigmatism, and a

209 From the total students diagnosed to have refractive error (n = 92), myopia constituted 83/92 (90.

210 s of these children were examined, including refractive errors, need for optical correction, and diag

211 Forty-one eyes of 21 patients with low refractive error, no visual impairment, and no known ret

212 d demographics, history of cataract surgery, refractive error, number of glaucoma medications, family

213 (odds ratio 1.230, P = .021) and uncorrected refractive error (odds ratio 0.834, P = .032) according

214 and chronic disease status, both uncorrected refractive error (odds ratio [OR], 1.36; 95% CI, 1.15-1.

215 High myopia was defined as myopic refractive error of </=6.0 diopters in the right eye.

216 es were from females, 74% were myopic with a refractive error of +3.00 to -17.00 diopters (spherical

217 presentation of 35.2 (14.2) years, and mean refractive error of -1.6 diopters.

218 ation with an initial targeted postoperative refractive error of either +8 diopters (D) (infants 28 t

219 luences the progression rate of the manifest refractive error of myopic children in a longer follow-u

220 taphyloma was 25.14 +/- 0.77 mm and the mean refractive error of the affected eyes was -4.28 +/- 2.65

221 alysis was used to assess the causal role of refractive error on AMD risk, using the 126 genetic vari

222 ed an effect of ethnicity, axial length, and refractive error on BMO-based parameters.

223 A (OR = 0.84 per week; p = 0.001), hyperopic refractive error (OR = 4.22; p = 0.002) and astigmatism

224 pia, ocular disease, or spherical equivalent refractive error outside of -3.00 to +8.00 diopters.

225 of ocular structures and the development of refractive error over the life-course is required, parti

226 .7 million cases of cataract, 2.3 million of refractive error, over 250,000 cases of glaucoma, and 11

227 sses were associated with age (P < .001) and refractive error (P < .001), but not other variables tes

228 ine in measures of binocular CDVA (P = .89), refractive error (P = .36), binocular eye alignment (P =

229 037) after adjusting for age (P = 0.001) and refractive error (P = 0.06).

230 .1), after adjusting for age (P < 0.001) and refractive error (P = 0.20).

231 d magnitude of absolute spherical equivalent refractive error (P<0.001).

232 ostoperative outcomes include visual acuity, refractive error, patient-reported visual function, and

233 c examination in such cases to determine the refractive error phenotype is challenging and costly.

234 Items from the National Eye Institute (NEI) Refractive Error Quality of Life Instrument (NEI-RQL-42)

235 tient satisfaction by National Eye Institute Refractive Error Quality of Life Instrument-42 (NEI RQL-

236 CL presence and thickness included hyperopic refractive error (R2 = 0.123; P = .045) and increased TC

237 Refractive errors ranged from -3.0 diopters (D) to 0.63

238 y of best-corrected visual acuity (BCVA) and refractive error (RE) after immediate sequential (ISBCS)

239 Uncorrected refractive error (RE) is a leading cause of visual impai

240 izing the burden of visual impairment due to refractive error (RE) worldwide is substantially higher.

241 monstrated its effects on the post-operative refractive errors (RE) one month after cataract surgery.

242 %) was the commonest VR disease, followed by refractive errors referred for retinal evaluation (16.7%

243 referred Practice Pattern(R) guideline (PPP) Refractive Errors & Refractive Surgery is unknown.

244 eliable systematic reviews to assist the AAO Refractive Errors & Refractive Surgery PPP.

245 ty of interventions included in the 2012 PPP Refractive Errors & Refractive Surgery.

246 st sensitivity, higher-order aberrations, or refractive error-related quality of life following both

247 st sensitivity, higher-order aberrations, or refractive error-related quality of life.

248 rast sensitivity, wavefront aberrations, and refractive error-related quality-of-life questionnaire.

249 Cases of uncorrected refractive error remained the major cause for presenting

250 Uncorrected refractive error remains a significant cause of impaired

251 Uncorrected refractive error remains the major causes of visual impa

252 ome-wide association meta-analysis (GWAS) of refractive error reported shared genetics with anthropom

253 ue to cataract (reversible with surgery) and refractive error (reversible with spectacle correction)

254 eoperative values, mean spherical equivalent refractive error (SEQ) increased by +0.78 diopter (D) (P

255 The mean preoperative spherical equivalent refractive error (SEQ) was -5.13 D (range, -2.75 to -8.0

256 ning, choroidal and retinal folds, hyperopic refractive error shifts, and nerve fiber layer infarcts.

257 Prevalence of significant refractive errors, specifically hyperopia, astigmatism,

258 Prevalence of myopic refractive error (spherical equivalent less than -0.50 d

259 Ophthalmologic findings such as refractive errors, strabismus, and fundus abnormalities

260 d benefits of the procedure, including lower refractive error, structural globe integrity, and faster

261 Astigmatism is a common refractive error that affects a significant portion of t

262 After adjusting for age and refractive error, the mean (SD) difference in the superf

263 For refractive errors, the association with GA remained afte

264 After correcting for refractive errors, the model can only reach healthy perf

265 ion to 31.6 million), because of uncorrected refractive error to 8.0 million (2.5 million to 16.3 mil

266 therapy, and analyze the effect of age, sex, refractive errors, type of amblyopia, and adherence to g

267 significant advantages in terms of residual refractive error, uncorrected distance acuity and contra

268 orrected visual acuity excluding uncorrected refractive errors (URE) as a visual impairment cause.

269 logMAR after refractive correction and unmet refractive error (UREN), individuals who had visual impa

270 intelligence explained 0.99% (p = 0.008) of refractive error variance.

271 The main outcome measures were refractive error, visual acuity, corneal topographic ker

272 symptoms, visual functioning, visual acuity, refractive error, visual field, diabetic retinopathy, ag

273 on visual acuity was -0.075 (0.087), and the refractive error was -0.071 (+1.91) diopters (D).

274 The actual postoperative refractive error was -0.30+0.47x6 (95% LCL, -2.36+1.31x3

275 ubfoveal choroidal thickness with the myopic refractive error was -10.45 mum per diopter.

276 Spherical equivalent refractive error was -2.82 +/- 1.65 D and -0.26 +/- 0.25

277 Overall prevalence of refractive error was 43 (10.2%).

278 Specifically, 1 D more hyperopic refractive error was associated with an odds ratio (OR)

279 Refractive error was calculated as sphere plus half nega

280 A less hyperopic/more myopic baseline refractive error was consistently associated with risk o

281 Refractive error was found significantly associated with

282 h participant, the eye with the worse myopic refractive error was included in this analysis.

283 In this young adult population, myopic refractive error was inversely associated with objective

284 etween genetic variants at these 39 loci and refractive error was investigated in 5200 children asses

285 months from standard fundus photographs, and refractive error was measured annually during the 6.5 ye

286 l image size (RIS) on the measurement of RA, refractive error was separately corrected with (i) trial

287 Spherical equivalent refractive error was the single best predictive factor t

288 rence between the intended and postoperative refractive errors was more than 3 standard deviations (S

289 survival, best-corrected visual acuity, and refractive error were analyzed for 3 consecutive time pe

290 BCVA, ECD, and refractive error were compared using linear mixed models

291 roidal thickness and axial length and myopic refractive error were obtained (r = -0.649, P < 0.001, a

292 ences between the intended and postoperative refractive errors were calculated as a compound spherocy

293 Visual acuity, manifest strabismus, and refractive errors were evaluated.

294 Mean refractive errors were hyperopic for all age groups but

295 Strabismus and significant refractive errors were risk factors for unilateral ambly

296 Refractive errors were significantly correlated with sev

297 We found most of the amblyogenic refractive errors were underdiagnosed in rural school ch

298 ess was additionally associated with age and refractive error, while ELM-ISOS was additionally associ

299 ms to be superior to DSEK and to induce less refractive error with similar surgical risks and EC loss

300 which was defined as the presence of myopic refractive error worse than -6.0 diopters with the prese