ライフサイエンスコーパス: regioisomer

1 ter produced the 1-aza-1,3-diene as the sole regioisomer.

2 varying amounts of the corresponding 2-amino regioisomer.

3 p, affording the natural product as a single regioisomer.

4 ylation of 2,5-dihydrofuran to form a single regioisomer.

5 ity at 1681 cm(-1) in the 1-benzoyl-3-pentyl regioisomer.

6 roposed that exclude the formation of a side regioisomer.

7 minal alkene exclusively generate the linear regioisomer.

8 6,7-dibromo isomer was observed as the major regioisomer.

9 isubstituted 3,3'-bisisoxazole over the 4,5'-regioisomer.

10 iers for those pathways leading to the major regioisomer.

11 d identified a 6,13-endoperoxide as the sole regioisomer.

12 ted aryls correspondingly preferred the beta-regioisomer.

13 )imidazolidin-2-one in 96% yield as a single regioisomer.

14 ently on the way to the N(beta)-fumaroyl-DAP regioisomer.

15 producing a stable trans oxetane as the only regioisomer.

16 r the pyrimidin-7-one or the pyrimidin-5-one regioisomer.

17 preference for sn-2 versus the sn-1 acyl-LPA regioisomer.

18 for the 18:2 fatty acyl-stabilized LPA sn-1 regioisomer.

19 alternative Diels-Alder product as a single regioisomer.

20 and modest regioselectivity for the desired regioisomer.

21 for exclusive formation of one or the other regioisomer.

22 clusively, and form a single alkene addition regioisomer.

23 of the Z,E configuration as the more active regioisomer.

24 g in the preferential formation of the gamma-regioisomer.

25 ycan connectivity and discrimination between regioisomers.

26 nantioselectivities as single diastereo- and regioisomers.

27 ,3-dipolar cycloaddition yielding unexpected regioisomers.

28 diate is responsible for producing undesired regioisomers.

29 -ray crystallographic data of three pairs of regioisomers.

30 le product was found among the four expected regioisomers.

31 esent in the drug molecule revealed a set of regioisomers.

32 le derivative gave a nearly equal mixture of regioisomers.

33 cells, and the most phototoxic are the 13(1) regioisomers.

34 to provide allylic alcohols 2m-2o as single regioisomers.

35 tical distribution of zirconacyclopentadiene regioisomers.

36 acid (NO(2)-LA), exists as a mixture of four regioisomers.

37 as DDQ or CA/H(+), for accessing bicarbazole regioisomers.

38 tures of N9 (usually desired), N7, and other regioisomers.

39 biliverdin IXalpha out of the four possible regioisomers.

40 acement of Val-7.39 profoundly affected both regioisomers.

41 tion with the acetyl group of the stabilized regioisomers.

42 by their inherent selectivities for specific regioisomers.

43 d much more effectively against the 4- and 7-regioisomers.

44 a substantial energetic difference for these regioisomers.

45 sis of AAB and ABC type triacylglycerol (TG) regioisomers.

46 ,2-dialkylidene cyclopentanes as mixtures of regioisomers.

47 s formed alongside either one or both of its regioisomers.

48 is employed, this method generally gives two regioisomers.

49 in CH(2)Cl(2) are (Z)-AM (anti-Markovnikov) regioisomers.

50 plex scaffolds, such as 11, contain multiple regioisomers.

51 stereoisomeric dihydroxytetrahydroporphyrin regioisomers.

52 romene-annulated bacteriochlorin stereo- and regioisomers.

53 n of the C-2, C-5, and C-6 prenylated A-ring regioisomers.

54 delate 1a to furnish adducts 5a-8a as single regioisomers.

55 ing step for one of the two possible product regioisomers.

56 hile N-Boc-alkyl ynamides yield a mixture of regioisomers.

57 hromatography of the ethyltoluene and cymene regioisomers.

58 ed for two of the ferrocene-based compounds, regioisomers 1 and 5.

59 11 did not prevent formation of the minor N7 regioisomer 13.

60 One regioisomer, 14,15-EET, stereospecifically blocks cycloo

61 pled 13, then monobenzylation gave separable regioisomers 15 and 16.

62 While the two regioisomers 1PCP-IP5 and 5PCP-IP5 inhibited Akt phospho

63 ted activity previously reported for the AdA regioisomer 2''-phospho-3''-dephospho-AdA 40.

64 The third possible regioisomer 2,6-diamino-3,7-dibromo product was formed,

65 On the other hand, epimerization of ortho-regioisomer 2-acetyl estrone occurred during the irradia

66 ielded (S)-phenylpropanol in 99% ee, and its regioisomer 2-MAP gave the opposite enantiomer, (R)-phen

67 ctivities for two series of substituted aryl regioisomers (2', 3', 4') showed that 4'-modified deriva

68 zole (NAI) to different pyridylcarbinol (PC) regioisomers (2-PC, 3-PC, and 4-PC) is demonstrated for

69 icosatrienoylglycerols (2-EG), including two regioisomers, 2-(11,12-epoxyeicosatrienoyl)glycerol (2-1

70 ypothesis that the natural lactam may be the regioisomer 27, a structure previously ascribed by Jarvi

71 report catalytic asymmetric syntheses of Trp regioisomers 2a-e, where the alanine unit is attached no

72 The 1-lithio regioisomer, 2a, is insoluble; in the presence of additi

73 ies correspond well to the observed ratio of regioisomers 3-5.

74 thiazoles 3, which included examples of both regioisomers 4 and 5.

75 hlorotoluene (affording 5a); the alternative regioisomer (5a') was obtained when using [Pd(cinnamyl)C

76 pecificity comparable to 4 was its 3-hydroxy regioisomer 8.

77 ligand and reaction conditions used, the C6 regioisomer a can be obtained in 4:1 ratio and excellent

78 Within each set of regioisomers, a slight red shift is revealed in the onse

79 rcinoma HEp2 cells show that the 15(2)-lysyl regioisomers accumulate the most within cells, and the m

80 8,9- and 14,15-EET regioisomers activated the Kir6.2 channel as potently as

81 leads to only one of the two possible indole regioisomers, along with minor decomposition products.

82 The use of temperature to select between two regioisomers also worked in the photocyclization of the

83 -substituted-furo[2,3-d]pyrimidine thiophene regioisomers, also inhibited growth of FR-expressing CHO

84 howed a preference for the 1,4-anti-triazole regioisomers among nAChRs.

85 A beta-4-beta' C70 bis-adduct regioisomer and an uncommon mono-adduct beta-malonate C7

86 2-Chloroaryl triflates (Tf) produce one regioisomer and the corresponding 2-chloroaryl mesylates

87 Various EET regioisomers and enantiomers are formed from arachidonat

88 reaction paths that provide mixtures of both regioisomers and stereoisomers of the hexahydroindane ad

89 one step baseline-resolves underivatized EET regioisomers and their enantiomers.

90 Each of the four EET regioisomers and their hydrolysis products (DHETs) has m

91 structures of AChE complexes with the TZ2PA5 regioisomers and their TZ2/PA5 precursors (2.1-2.7 A res

92 Comparisons of the regioisomers and thermodynamics for addition reactions o

93 demonstrate good selectivity for the linear regioisomer, and the reactions with alkynes provide enon

94 Alkene stereoisomers, vinylogous ester regioisomers, and beta-diketone congeners are also synth

95 tial reaction rates with MOF topology and PC regioisomer are consistent with preconcentration effects

96 ission spectra of the neutral and protonated regioisomers are distinct from each other, and generally

97 f 11,12-EET, we also found that all four EET regioisomers are equipotent activators of the K(ATP) cha

98 A number of different F4-NP regioisomers are formed from the peroxidation of DHA.

99 e case of the 1,3,4-thiadiazol-2-amines, the regioisomers are formed in approximately equal amounts a

100 When regioisomers are possible, the more crowded (doubly orth

101 with our hypothesis that 4- and 20-series NP regioisomers are preferentially generated.

102 ioactivities; therefore, to determine if the regioisomers are quantitatively or qualitatively differe

103 d reagent leads to the formation of a single regioisomer as a result of the pronounced directing effe

104 ncreased mechanical deformability of the 1,5-regioisomer as compared to the 1,4-isomer.

105 ulting in the formation of the unprecedented regioisomers as major products, which is in contrast to

106 ed with ribosome affinity for the anti (1,4)-regioisomers as revealed by measured Kd values.

107 conjugates are L-shaped, the 15(2) and 13(1) regioisomers assume extended conformations, and the 13(1

108 ters with linoleic acid and the synthesis of regioisomers at position 3'.

109 From 40 to 120 psi, both regioisomer (b:l) and enantiomer (R:S) ratios are propor

110 , diborylation can be achieved with a single regioisomer being formed in certain cases.

111 Activation via this route is rapid for the 3-regioisomers, but is considerably slower for the 2-subst

112 , allowing the selective formation of either regioisomer by careful choice of reaction conditions.

113 at MDA can be converted into two glutathione regioisomers by human liver microsomes, but only the 5-(

114 ynthetic route to prepare all four carboline regioisomers by photostimulated cyclization of anilinoha

115 Each of these regioisomers can be obtained as the major product depend

116 either one of the two possible beta-lactone regioisomers can be obtained selectively.

117 rence in profile between the 1,2,4 and 1,3,4 regioisomers can be rationalized by their intrinsically

118 The analytical protocol for regioisomer characterisation of fatty acids in a triacyl

119 gioisomers of the lead revealed that the cis regioisomer, (+/-)-cis-2-(3,5-dichlorphenylcarbamoyl)cyc

120 d the characteristic headgroup fragment, the regioisomer composition from fragment ions unique to the

121 The more stable dihydropyran regioisomer could not be generated due to poor geometric

122 yr) at ambient temperature gave the betabeta regioisomers, Cp(2)Zr[2,5-Me(2)-3,4-Mes(2)C(4)] and Cp(2

123 c analyses of AChE complexes with the TZ2PA6 regioisomers demonstrated that syn product association i

124 proceed to give head-to-tail or head-to-head regioisomers, depending on the nature of the solvent emp

125 eads to the synthesis of the most conjugated regioisomer derivative.

126 gue 2,2'-bithieno[3,2-b]thiophene, all three regioisomers derived from the dimerization of thieno[3,2

127 14,15-DHET is the major regioisomer detected in the plasma samples while other r

128 tification and quantitation of monoglyceride regioisomers directly from tissue extracts.

129 t methods for the quantitative prediction of regioisomer distribution in kinetically controlled nucle

130 Tethers less than 6 carbon atoms lead to 1,3-regioisomers due to conformational restrictions.

131 The structures of the two regioisomers Eu(3+) subset1 and Eu(3+) subset2 were assi

132 Of the five possible indenofluorene regioisomers, examples of a fully conjugated indeno[1,2-

133 [3]Naphthylene regioisomers exhibited distinct optoelectronic propertie

134 The 3-lithio regioisomer exists as tetranuclear [2-(Me2NCH2)C10H6Li-3

135 gs in the exTTFs, as well as the more stable regioisomers for the bisadducts 28.

136 lectrostatic interactions (i.e., for the 1,5-regioisomer formation from 1-fluoro-2-butyne and methyl

137 s), and excellent regioselectivity (only one regioisomer formed).

138 triazoles were compared to the 1,4- and 1,5-regioisomers formed in the reaction of an azide with a t

139 xidation of internal alkynes as the opposite regioisomers frequently predominate.

140 us report, these reactions yield mixtures of regioisomers generally favoring the 2,2,3-trisubstituted

141 CHCl3 solution the relative stability of the regioisomers (Gexp = 1.2 kcal/mol; Gcalcd = 3.2 kcal/mol

142 ore hindered, less stable, and usually minor regioisomer has been developed.

143 When a terminal alkyne is employed, only one regioisomer has been isolated.

144 To date, the availability of regioisomers has been dictated by the innate electronics

145 The formation of two benzofuran regioisomers has been explained in terms of competitive

146 Mixtures of regioisomers have been obtained when unsymmetrical alkyn

147 ced intermediates representing each of these regioisomers have been prepared, and the new C-6 interme

148 The set of 131 phospholipids (including regioisomers) here identified represents the most compre

149 nd (13)C chemical shift assignments for each regioisomer, heteronuclear multiple-bond correlation spe

150 ols and furyl sulfonamides generate only one regioisomer in each case.

151 d to characterize involvement of the 5-PAHSA regioisomer in the adaptive metabolic response of white

152 with sn-18:1-16:0-18:1 as the most prevalent regioisomer in the milk (13.8+/-2.7%).

153 yielded the 2-carbaldehyde (3) as the major regioisomer in up to 68% yield (with ligand L2) along wi

154 or the preparation of all TG enantiomers and regioisomers in a mixture, while the stereospecific este

155 ular nature of the process, providing single regioisomers in all cases.

156 consisted of four, rather than two, nitrated regioisomers in approximately equal abundance.

157 ion 4a-4l and 5a-5l, respectively, as single regioisomers in good to excellent yield with uniformly h

158 displays regioselectivity in forming single regioisomers in good yields.

159 The composition of TG enantiomers and regioisomers in hazelnut oil and human plasma samples is

160 of a series of unprecedented [3]naphthylene regioisomers in high yields, where three naphthalenoids

161 allows for quantification of the designated regioisomers in one simple, rapid chromatographic proced

162 baseline-resolves underivatized EET and DHET regioisomers in one step.

163 reactivity differences between naphthopyran regioisomers in terms of the alignment of the target C-O

164 terization of purified 3-ring and 4-ring MDA regioisomers in this current study.

165 The percentage of M regioisomer increased significantly with 1 and BrCl in M

166 ir unoxidized counterparts while maintaining regioisomer-independent elution, allowing quantification

167 ntify multiple full-length oxFA species in a regioisomer-independent manner without the need for time

168 The preferred regioisomer is determined by thermodynamic rather than k

169 ethyl [6,6]-pyrrolidino-Y3N@C80 to the [5,6] regioisomer is reported, as well as the synthesis, chara

170 e pathway leading to the tetrahydroquinoline regioisomer is significantly more sensitive toward the e

171 aterial, it is possible to prepare different regioisomers just by appropriately choosing the catalyst

172 Additionally, the symmetrically arranged regioisomer L(4a') was also synthesized as well as its [

173 Complexation with Ni(II) of the major regioisomer led to good quality crystals, suitable for X

174 lglucopyranose and N'-biphenoylglucopyranose regioisomers led to the production of a focused set of l

175 rovides a quick access to a large variety of regioisomer libraries that can be tested for selective r

176 e formation of two different hydroxybenzoate regioisomers, likely in a single active site.

177 The synthesis of thiazole(Tz)-based regioisomer materials using selective direct arylation t

178 port the notion that these novel O-3 and O-4 regioisomers may represent novel promising leads for dru

179 the formation of the product as a mixture of regioisomers mediated by a ring-opening reaction.

180 Seven examples provided inseparable regioisomer mixtures of -two to three compounds (16 nucl

181 The ratio of the three regioisomers N-alkyl-N-nitrosourethane 3, azoxy 4, and O

182 hynyl)benzene with zirconocene gave a single regioisomer (o-xylyl groups in both beta-positions) whil

183 aminofuro[2,3-d]pyrimidine (1) [which is a 6-regioisomer of LY231514 (Alimta)] and a 6-subsituted 2-a

184 cyanates enables a facile access to a single regioisomer of N(1)-substituted 2-aminobenzimidazoles as

185 rtorum, a producer of desertorin A, the 6,8'-regioisomer of orlandin.

186 ultimately converging to provide the desired regioisomer of the amine products.

187 ndolo-, pyrrolo[2,1-a]isoquinolines 15a-g, a regioisomer of the bisindolo[1,2-a]quinolines used as or

188 n good yields giving a single diastereo- and regioisomer of the branched allylic acetate trans-vinyls

189 A regioisomer of the phenyltriazole substituent, that is t

190 Orthocetamol is a regioisomer of the well-known pain medication paracetamo

191 the access to either formal hydrosilylation regioisomer of unsymmetrical aliphatic-substituted inter

192 nine, 2 and 3, respectively, which represent regioisomers of (2S,3R)-ceramide (1).

193 Furthermore, the isolation of the regioisomers of (i) ethyltoluene and (ii) cymene, togeth

194 at allowed for distinction between the three regioisomers of 1,2-di(9Z-octadecenoyl)-sn-glycero-3-[ph

195 hod for the preparation of both 1,4- and 1,6-regioisomers of 1-substituted 4(6)-trifluoromethyl-pyrim

196 s rich in CLA, with a ratio of sn-1,3/sn-1,2 regioisomers of 21.8, compared to 2.3 for Novozym(R) 435

197 c pairs of AAB type TGs and five triplets of regioisomers of ABC type TGs with acyl carbon number (AC

198 an anomers, sialoglycan linkage isomers, and regioisomers of afucosylated and fucosylated sulfoglycan

199 yrrolo[2,3-d]pyrimidine antifolate thiophene regioisomers of AGF94 (4) with a thienoyl side chain and

200 lpha-MeDA and 6-(glutathion-S-yl)-alpha-MeDA regioisomers of alpha-MeDA.

201 ensional (1)H and (13)C NMR assigned the two regioisomers of benzo[a]pyrene-7,8-catechol monosulfate

202 Here two regioisomers of bis(10H-phenothiazin-10-yl)dibenzo[b,d]t

203 Two regioisomers of bis[1]benzothieno[1,4]thiazine are unexp

204 This is the first time that the regioisomers of carotenoid esters have been identified i

205 Novel regioisomers of conformationally constrained analogues o

206 r detected in the plasma samples while other regioisomers of DHETs are probably present at too low a

207 All four approaches generate single regioisomers of diversely substituted chlorins, and in e

208 Thus, both regioisomers of enantioenriched 1,2-aminoalcohols can be

209 Each of the four regioisomers of epoxyeicosatrienoic acids (EETs) is a ca

210 Both the BacA and BacB products are regioisomers of H(2)HPP (dihydro-4-hydroxyphenylpyruvate

211 ion of PPARgamma-dependent LNO(2) signaling, regioisomers of LNO(2) were synthesized and characterize

212 ctrometric analysis to identify and quantify regioisomers of monoglycerides in biological samples.

213 ng in the case of each reagent two different regioisomers of NHC-coordinated cyclic germylenes.

214 revious studies with the naturally occurring regioisomers of nitrolinoleic acid revealed that the iso

215 We conclude that the regioisomers of NO(2)-LA are not functionally equivalent

216 These regioisomers of OA-NO2 were quantified in clinical sampl

217 F(2)-isoprostanes are stereo- and regioisomers of prostaglandin F(2alpha) (PGF(2alpha)) an

218 xides can be manipulated to provide pairs of regioisomers of pyrrole-modified porphyrin N-oxides.

219 f [RR](+) product ions and the proportion of regioisomers of TGs.

220 tion-elimination process, yielding different regioisomers of the allylic alkylation products in a hig

221 Resolution of the regioisomers of the lead revealed that the cis regioisom

222 not available in the stacked dimer or other regioisomers of the polymer which possess lesser degrees

223 omerically pure diastereomers of the several regioisomers of these important human metabolites.

224 cile access to 1,4-cycloheptadienes that are regioisomers of those formed from the tandem cyclopropan

225 NTP incorporation, consists of a set of four regioisomers of trifluoromethyl benzimidazole.

226 the characterization of the [5,6] and [6,6] regioisomers of trimetallic nitride endohedral metallofu

227 ure (benzene, toluene, ethylbenzene, and the regioisomers of xylene), into their pure components, in

228 the fatty acid composition (determination of regioisomers) of the lipids without purification of the

229 dology enabled the synthesis of each desired regioisomer on 50-75 g scale with minimal purification.

230 ly substituted aryne either gave mixtures of regioisomers or failed.

231 classes because the precursors that lead to regioisomers other than those of the 4- and 20-series ca

232 ges of alkynes correlated qualitatively with regioisomer outcome.

233 quantification of all DAG species including regioisomers, particularly in an approach of shotgun lip

234 With the exception of 3 and ICl, the (E)-AM regioisomers predominate when pyridine was added as an a

235 ifying and quantifying DAG species including regioisomers present in lipid extracts of biological sam

236 Of these, 32 yielded single regioisomer products, and six resulted in separable mixt

237 electrophilic cyclization and separation of regioisomers provided the corresponding 2,7,3',6'-tetras

238 as developed, validated and caffeoyl glucose regioisomers quantified for the first time in dietary pl

239 The regioisomer ratios (3 degrees,2 degrees /2 degrees,3 deg

240 Reversed regioisomer ratios were observed with 6,7-epoxygeranyl a

241 ed at 25 degrees C, most of the EET and DHET regioisomers remained intact when suspended in alkaline

242 le in the preparation of the pyrimidin-5-one regioisomer represents a correction of previously report

243 Herein, the preparation of the regioisomer (S)-N(1)-methyl-2-[2'-(3''-methoxy-4''-hydro

244 ed by allylation typically gives mixtures of regioisomers (S(N)2 and S(N)2' products), whereas transm

245 u-2.60 and Val-7.39 of LPA(3) underlying the regioisomer-selective interaction with the acetyl group

246 The (+/-)-14,15-EET regioisomer selectively rescues breast cancer cells from

247 )H and (11)B NMR studies on two boro-oxazine regioisomers showed that selective deprotection can be p

248 The 1-benzoyl-3-n-pentylindole inverse regioisomer shows a base peak at m/z 105 for the benzoyl

249 djacency penalty rule), (iii) the changes in regioisomer stability due to the chemical nature of the

250 eration and activates apoptosis, whereas its regioisomers stimulate growth.

251 e pyrrole or the furan derivative is pH- and regioisomer-structure-dependent.

252 electron-poor alkynes are shown to favor the regioisomer that has either the most favorable TS intera

253 ynes, on the other hand, generally favor the regioisomer that has the smaller TS distortion energy.

254 deborylation reactions provide monoborylated regioisomers that complement those prepared by C-H boryl

255 d metabolic stability in comparison to its 5-regioisomer, the 3-amino-isoxazole group was combined wi

256 three possible disulfide-cross-linked NCR247 regioisomers, the reduced peptide, and a variant lacking

257 to afford 5-alkyl or 4-alkyl cyclopentenone regioisomers: the former conditions afford 5-alkyl subst

258 minimal discrimination against the 5- and 6-regioisomers, they discriminated much more effectively a

259 aining 18:3 fatty acyl chains as well as TAG regioisomers to be separated and identified.

260 t similar changes were not observed with the regioisomer (+/-)-trans-4,5-dihydroxy-4,5-dihydrobenzo[a

261 The mixture of regioisomers, trapped as carboxylates, formed in an equi

262 ion in molecular solvents led to mixtures of regioisomers under similar conditions.

263 ectroscopy, and it converted to a mixture of regioisomers upon heating via a sigmatropic rearrangemen

264 determined, and the formation of the target regioisomer was demonstrated.

265 t-dependent polymerization of one macrocycle regioisomer was observed and characterized.

266 ed (R > or = 1.3); 10 pg of an EET or a DHET regioisomer was readily detectable at 194 nm.

267 An access to N-sulfonylated 2-substituted regioisomers was established.

268 Formation of all three possible regioisomers was only observed in the reaction of one of

269 When subjected to CE, the EET and DHET regioisomers were baseline resolved (R > or = 1.3); 10 p

270 The regioisomers were characterized by elemental analyses (C

271 Minor amounts of the M regioisomers were formed with 1 and 2 and BrCl.

272 Three EET regioisomers were found to be substrates for COX, based

273 enzyme assay, whereas the corresponding C-4 regioisomers were less potent.

274 (KRs) or thermodynamically (TRs) controlled regioisomers were obtained at room temperature and on he

275 Single regioisomers were obtained when three atoms linked the k

276 f medicinal chemistry where para-substituted regioisomers were perhaps more easily accessed, and furt

277 sis products including diolein and monoolein regioisomers were quantified within a single HPLC run.

278 Purified methylenedianiline (MDA) regioisomers were structurally characterized and differe

279 Both regioisomers were synthesized from the cyclocondensation

280 All three regioisomers were synthesized in good yields and in five

281 Isolated yields of single regioisomers were typically 65-84%, while observed regio

282 ly proceed to an equilibrium distribution of regioisomers where Rh-CH(CH(2)OH)X is the predominant th

283 d substrate for the corresponding 1,3-distal regioisomer, whereas the opposite holds for GpA.

284 increased the EC(50) of the sn-2 acetyl-LPA regioisomers, whereas alanine replacement of Val-7.39 pr

285 solved by HRdm, including two monosaccharide regioisomers which differed in drift time by only 0.8%.

286 DG meta-substituted aryls preferred the beta-regioisomer, which was demonstrated by 3,5-dimethoxy- an

287 ome extent, favored the cyclopentenone alpha-regioisomer, while the EWG-substituted aryls correspondi

288 ng group desosamine affords a 1:1 mixture of regioisomers, while synthetic anchors shift YC-17 analog

289 Subsequent coupling of each regioisomer with diethyl-l-glutamate followed by saponif

290 regioselectivity toward the targeted 3-amino regioisomer with significantly shorter reaction times an

291 ty and potency against human tumor cells, 3b regioisomers with [1,3] (7 and 8) and [1,2] (4, 5, and 6

292 lpha-methylene lactone reacts to mixtures of regioisomers with a high proportion of (E)-alpha-benzyli

293 gen bonds, the reaction selectively leads to regioisomers with C4 symmetry.

294 the latter result in the 4-alkyl substituted regioisomers with concomitant oxidation at the gamma-pos

295 Two alternative regioisomers with different polymer attachment points ar

296 roducts of hydrohydroxymethylation as single regioisomers with excellent levels of enantiomeric enric

297 duct, and carbamates gave a 50:50 mixture of regioisomers with phthalimide as the nucleophile.

298 substitution is favored over meta and ortho regioisomers, with p-chlorophenyl (p-ClPh) being one of

299 f the reaction, opening the access to either regioisomer without modification of the starting substra

300 he differentiation of discrete monoglyceride regioisomers without chromatography through their distin