ライフサイエンスコーパス: regulation of expression

1 rhesus tissues demonstrated tissue-specific regulation of expression.

2 ns and/or via changes in temporal or spatial regulation of expression.

3 was complex, suggesting post-transcriptional regulation of expression.

4 e active rather than passive participants in regulation of expression.

5 xpression, whereas low levels resulted in up-regulation of expression.

6 he infection, suggesting an infection-driven regulation of expression.

7 vation disturbed both temporal and cell-size regulation of expression.

8 tion of IFNlambda4 to determine its role and regulation of expression.

9 hich genes might be subject to tRNA-mediated regulation of expression.

10 ion machinery to accomplish rigorous spatial regulation of expression.

11 oter, and dramatically altered iron-mediated regulation of expression.

12 II/Gu, its chromosomal localization, and the regulation of expression.

13 posin displayed similar temporal and spatial regulation of expression.

14 undergo thigmomorphogenesis and TCH gene up-regulation of expression.

15 3' of the US3 TATA box are required for down regulation of expression.

16 eam sequence may be involved in quantitative regulation of expression.

17 iana, the members of which show differential regulation of expression.

18 owed unusually rapid decay, indicating tight regulation of expression.

19 ages that have evolved a tight, hierarchical regulation of expression.

20 2, was previously shown to be essential for regulation of expression.

21 me that the LINC complex facilitates mechano-regulation of expression across the genome.

22 ervations reveal a crucial role for LTCCs in regulation of expression, activity and stability of aqua

23 genes were found to have at least 3-fold up-regulation of expression after treatment in each cell li

24 Our results indicate some cross-regulation of expression among ABI3, ABI4, and ABI5 and

25 tems have revealed fundamental shifts in the regulation of expression among critical genes in the not

26 Compensatory up-regulation of expression and activation of Vav3 in Vav1/

27 Using shRNA knockdown, we confirmed c-Myc regulation of expression and activity of AR-FL and AR-Vs

28 Down-regulation of expression and activity of erbB2, a member

29 We investigated the regulation of expression and activity of the MC1R in pri

30 nic changes in sodium intake caused parallel regulation of expression and amount of receptor protein

31 However, few demonstrate the exquisite regulation of expression and breadth of functional impor

32 y have dramatically different mechanisms for regulation of expression and enzymatic activation.

33 is a secreted, pentameric glycoprotein whose regulation of expression and function are not well under

34 lectively, the present results shed light on regulation of expression and function of ICAM-1 on neutr

35 ere, we investigated the role of MTA1 in the regulation of expression and function of MyD88, a proxim

36 asiveness of tumor cells may also involve up-regulation of expression and function of the autocrine m

37 expression of NeuroD1 subsequently leads to regulation of expression and function of the nicotinic a

38 that Nrf2 regulates Cul3-Rbx1 by controlling regulation of expression and induction of Cul3-Rbx1.

39 These results implicated Nrf2 in the regulation of expression and induction of INrf2.

40 n human and mouse kidney was studied and the regulation of expression and localization of this subuni

41 cells, inhibition of PI3K was followed by up-regulation of expression and phosphorylation of multiple

42 Taken together, these data indicate that the regulation of expression and processing of LAT RNA withi

43 homeotic gene as a result of changes in both regulation of expression and specific alterations in the

44 Relatively little is known about the regulation of expression and stability of BubR1 (or othe

45 present study is the first demonstration of regulation of expression and transactivation ability of

46 rates of murein hydrolases as well as in the regulation of expression and/or activity of some murein

47 Our results implicate ct in the regulation of expression and/or function of two homeotic

48 s within TR genes may be relevant to complex regulation of expression and/or organelle- and cell type

49 ncomitant loss of function in Chk2 (via down-regulation of expression) and p53 (via mutation) occurs

50 , genomic organization, molecular structure, regulation of expression, and function.

51 er analysis of the transcriptional function, regulation of expression, and phenotypic effects will he

52 o explore the cells of origin, localization, regulation of expression, and putative functions of IHH

53 to examine CCRL2 expression in RA, cytokine regulation of expression, and the source of a putative l

54 These data indicate that there is a mutual regulation of expression between p53 and AR.

55 ding was the dramatic change observed in the regulation of expression between proteases and their cog

56 e fragmentation pattern of the mRNA, and the regulation of expression by a repression mechanism descr

57 ressed from a foreign promoter to circumvent regulation of expression by FlgM, which is itself a fila

58 r the control of class II expression and the regulation of expression by interferon-gamma.

59 course of regeneration, direct and indirect regulation of expression by p53 is mediated in a gene-sp

60 sential vitamins, with an overall twofold up-regulation of expression compared with free-living cells

61 Because glycolytic enzyme up-regulation of expression contributes to glycolytic flux,

62 n mouse and man and striking spatio-temporal regulation of expression during embryogenesis, suggest t

63 n, we characterized its tissue distribution, regulation of expression during hematopoietic differenti

64 R shortening in S. pombe coordinates with up-regulation of expression for genes involved in translati

65 ession quantitative trait and determined cis regulation of expression for nine of the miRNAs and of t

66 cific ribosomal proteins to allow autogenous regulation of expression from large multi-gene operons,

67 The regulation of expression from the URE2 internal ribosome

68 The regulation of expression from this promoter may involve

69 Aspergillus fumigatus induced differential regulation of expression in 1,827 genes (P < 0.05).

70 e cDNAs, their genomic arrangement and their regulation of expression in different fly tissues and sp

71 For the otpb enhancer, regulation of expression in dopamine neurons requires mu

72 edium (4710 +/- 2643), and verified the down-regulation of expression in medium that contained only g

73 ple of the utilization of different modes of regulation of expression in T and B cells.

74 Efficient regulation of expression in these systems makes use of s

75 ributing to nearly 90% of all UFs, but their regulation of expression is poorly characterized.

76 While numerous studies have investigated regulation of expression level, little is known about ge

77 1) direct interaction between receptors, 2) regulation of expression levels and localization, and 3)

78 cations appear to confer risk of T2D via the regulation of expression levels for a large number (266)

79 ose of wild-type mice indicating possible co-regulation of expression levels.

80 inding in tick-transmitted bacteria, and the regulation of expression may be broadly applicable to un

81 ly regulated Ras isoform with significant up-regulation of expression observed pre-term in stomach, i

82 associated with metformin IC50 through trans-regulation of expression of 11 or 26 genes with P-value

83 Marked up-regulation of expression of 24p3/lcn2 was seen throughou

84 been shown to play an important role in the regulation of expression of a subclass of adipocyte gene

85 hain reaction (Q-RT-PCR) was used to confirm regulation of expression of a subset of 6 genes with imp

86 a role for the daf-7 TGF-beta pathway in the regulation of expression of a subset of chemoreceptor ge

87 thelial cells is associated with up-and-down regulation of expression of a variety of genes including

88 of the organism at acidic pH also results in regulation of expression of a variety of genes, such as

89 reorganization of the actin cytoskeleton to regulation of expression of a wide range of genes, inclu

90 ymphoid tissue organization, we analyzed the regulation of expression of adhesion molecules and chemo

91 on of DC function was associated with the up-regulation of expression of Ag-processing machinery comp

92 Down-regulation of expression of AKT kinase by RNA interferen

93 The independent regulation of expression of all of these genes, implied

94 ulatory system is an important mechanism for regulation of expression of aminoacyl-tRNA synthetase, a

95 ene expression and the first report of viral regulation of expression of an RNA processing factor.

96 eptide Y and agouti-related protein and down-regulation of expression of anorexigenic neuropeptides p

97 d the transcription of PSA not only via down-regulation of expression of AR, but also by a direct inh

98 d in activation of lymph node T cells and up-regulation of expression of B220, CD11a, and CD44 and ca

99 Regulation of expression of both human GCS subunit genes

100 a correlation with the complex developmental regulation of expression of btk.

101 To understand the regulation of expression of cagA, picB, associated with

102 ulation of exit from the cell cycle; and (d) regulation of expression of carbonic anhydrases 9 and 12

103 Regulation of expression of CARD15/NOD2 by cytokines was

104 This enhancement was associated with the up-regulation of expression of CCR5, a primary coreceptor f

105 rapid induction of expression of CD80 and up-regulation of expression of CD86, incubation with killed

106 Down-regulation of expression of Cep55 was accompanied by rep

107 However, little is known about the regulation of expression of chemokine receptors in the b

108 The regulation of expression of components and substrates of

109 This study tests the hypothesis that the regulation of expression of connexin 43, a gap junction

110 However, the molecular regulation of expression of Cosmc, which is encoded by a

111 s, because these cells showed significant up-regulation of expression of costimulatory molecules B7.1

112 owever, molecular mechanisms involved in the regulation of expression of COX-2 are not well understoo

113 Currently, knowledge of the regulation of expression of COX-2 by endogenous cell-sur

114 se loops can be generated by auto- and cross-regulation of expression of CREB proteins, via CRE eleme

115 However, the mechanisms responsible for the regulation of expression of cutaneous adhesion molecules

116 ment of Drosophila is at least partly due to regulation of expression of cuticle patterning genes by

117 fungal cell, and report the transcriptional regulation of expression of CWDE genes in both saprophyt

118 important factors in the differentiation and regulation of expression of dendritic cell-associated ma

119 We conclude that through regulation of expression of DNA damage response genes, C

120 factor HNF-3beta has been implicated in the regulation of expression of each of these MODY genes, su

121 ion, consistent with their role in circadian regulation of expression of eas(ccg-2).

122 ific transcription factor likely involved in regulation of expression of endogenous genes.

123 rogenesis at least in part through molecular regulation of expression of endothelial adhesion molecul

124 scussed, addressing the associated roles and regulation of expression of endothelial cell luminal and

125 enomic sequences that may be involved in the regulation of expression of exons 1b and 1c of the RFC1

126 We demonstrate that regulation of expression of extracellular matrix compone

127 knowledge, this is the first example for the regulation of expression of flagella by hydrogen in any

128 NA immediately flanking fruA, to explore the regulation of expression of fruA by the carbohydrate sou

129 A better understanding of the regulation of expression of FUS may give insight into ho

130 a broad range of biological roles, including regulation of expression of genes and chromosomes.

131 ithelial cell growth is mediated by androgen regulation of expression of genes controlling cell cycle

132 produced at 37 degrees C and are involved in regulation of expression of genes encoding stress respon

133 Marked up regulation of expression of genes involved in interferon

134 of intracellular redox state by Nrf2-related regulation of expression of genes involved in intracellu

135 re accepted effects of this pathway, but the regulation of expression of genes involved in mesoderm s

136 he hexosamine biosynthesis pathway (HBP) via regulation of expression of glutamine:fructose-6-phospha

137 Up-regulation of expression of group I and II mGluRs is cor

138 It is concluded that although a degree of regulation of expression of GSTs occurs in human pancrea

139 We conducted experiments to study the regulation of expression of heat shock proteins (HSPs) i

140 activation of interleukin-6-STAT3 signaling, regulation of expression of hepatic C/ebpalpha, C/ebpbet

141 We have examined the regulation of expression of human colonic MCT1 by butyra

142 due to inhibition of the fasting-induced up-regulation of expression of hypothalamic orexigenic neur

143 lls and differentiated T cells results in up-regulation of expression of I.1 isoform of HIF-1 alpha m

144 hanism of action, and the molecular basis of regulation of expression of IL-21 and its receptor.

145 ions demonstrating both S. aureus-induced up-regulation of expression of IL-6 and IL-12p40 mRNA and s

146 nscription activation, which is important in regulation of expression of immediate-early response gen

147 The fast initial down-regulation of expression of inflammatory mediators coinc

148 Regulation of expression of inflammatory mediators was e

149 ained dysfunctional, which suggests that the regulation of expression of inhibitory receptors is unco

150 Temporal and spatial regulation of expression of introduced genes, or of RNAi

151 equences of depletion of isoprenoid pools on regulation of expression of isoprenylated proteins have

152 Mechanisms governing the regulation of expression of its subunit genes remain lar

153 nfiltration was followed by the transient up-regulation of expression of LIFR, IL-6, and IL-6R in ens

154 Hence, discordant regulation of expression of major histocompatibility com

155 tion factors also play critical roles in the regulation of expression of many functional genes in the

156 f the POU domain factors, is involved in the regulation of expression of many tissue-specific and hou

157 e results indicate a key role for Ids in the regulation of expression of Math1 and hair cell differen

158 dy, we investigated the role of SphK1 in the regulation of expression of matrix metalloproteinase 1 (

159 esults suggest that TIMP3 is involved in the regulation of expression of matrix metalloproteinases in

160 ed immunosorbent assays were used to examine regulation of expression of metalloproteinases and chemo

161 reduction in iron cofactor availability, and regulation of expression of methyl-modifying enzymes.

162 gulation might play an important role in the regulation of expression of miRNAs in acute leukemias.

163 Recent studies implicated E2F in regulation of expression of mitochondria-associated gene

164 MKK4 signaling cascade showed a loss or down-regulation of expression of MKK4 or c-Jun, a downstream

165 RK-MAPK and PKC pathways are involved in the regulation of expression of MMP-2 and TIMP-1 and -2.

166 on antitumor agents results in p53 dependent regulation of expression of most TLR genes in human prim

167 Analyses of hormone regulation of expression of mRNA for the aleurone RNase

168 developed slowly, and was associated with up-regulation of expression of mRNA for the MAC inhibitor C

169 ping study and functional analyses implicate regulation of expression of MSMB as a plausible mechanis

170 ons, CD63, MMP-3 and Cdc42, and that PYY/NPY regulation of expression of mucosal proteins such as vil

171 n promoter that may contribute to coordinate regulation of expression of multiple cell-type specific

172 vo results suggest a carbon source-dependent regulation of expression of Mxr1-activated genes by 14-3

173 Here, pre-let-7a transfections led to down-regulation of expression of MYC and its target genes and

174 This includes up-regulation of expression of N-cadherin and c-MYC and dow

175 d with an increased proliferation and a down-regulation of expression of negative regulators of the J

176 asmic-interacting protein, BOD1, leads to up-regulation of expression of numerous genes modulating fa

177 Noncoding RNAs have been implicated in the regulation of expression of numerous genes; however, the

178 ate an important role for these genes in the regulation of expression of other CoA biosynthesis genes

179 pecies-specific and conserved mechanisms for regulation of expression of P-selectin, we cloned the 5'

180 ingly, one cell line exhibited complete down-regulation of expression of p14(ARF), with only slight d

181 xpression of p14(ARF), with only slight down-regulation of expression of p16(INK4a).

182 expression of N-cadherin and c-MYC and down-regulation of expression of p53 and E-cadherin.

183 ort that DNA methylation plays a role in the regulation of expression of pathogenically relevant gene

184 ons indicate that CsrABb plays a role in the regulation of expression of pathophysiological determina

185 pilB, a transcription factor involved in the regulation of expression of pili, from Neisseria gonorrh

186 of PLD (hPLD1-K898R or mPLD2-K758R) or down-regulation of expression of PLD with PLD1 or PLD2 siRNA

187 and NF-kappaB signaling, as well as the down-regulation of expression of prosurvival genes.

188 ese results show that desiccation-induced up-regulation of expression of protective genes may be nece

189 Its primary function is the regulation of expression of pyrimidine biosynthetic (pyr

190 t cause cell cycle arrest but did cause down-regulation of expression of RB, p107, p130, and other pr

191 ic acid biosynthesis in murine liver through regulation of expression of regucalcin or senescence mar

192 the first evidence that this is mediated by regulation of expression of replication-dependent core h

193 utant cspE was functional with respect to up-regulation of expression of rpoS, but, unlike the wild-t

194 3)-dependent 32Dcl3 did not result in the up-regulation of expression of secondary granule genes comp

195 ting possibility that fungi use differential regulation of expression of secondary metabolite gene cl

196 of tooth morphogenesis through antagonistic regulation of expression of secreted Wnt antagonists, in

197 umber of genes was performed and a strong up-regulation of expression of secretory phospholipase A(2)

198 ia nitrite reductase NirS contributes to the regulation of expression of selected virulence factors i

199 ersus P-selectin represents a novel level of regulation of expression of selectin ligands and lymphoc

200 morphogenesis by pathways other than through regulation of expression of semaphorin and ephrin.

201 first of which we are aware, to demonstrate regulation of expression of SERCA2a, a critical determin

202 our results show that there is differential regulation of expression of several genes in the mannose

203 protein responsible for post-transcriptional regulation of expression of several iron metabolism prot

204 s may be patterned during development by the regulation of expression of single genes.

205 mal phenotype is accompanied by gradual down-regulation of expression of Smad3.

206 Such ribosome stalling is used for regulation of expression of some bacterial and eukaryoti

207 for cell proliferation in contrast with the regulation of expression of specific genes.

208 osphorylation targets that might explain Stk regulation of expression of specific operons and the pos

209 can respond to fetal demand signals through regulation of expression of specific placental transport

210 the Type I IFN receptor (IFNR), there is up-regulation of expression of Sprouty (Spry) proteins 1, 2

211 results provide insight into KstR2-mediated regulation of expression of steroid catabolic genes and

212 role played by host-pathogen interactions in regulation of expression of streptococcal virulence fact

213 s in muscle fibers that may experience local regulation of expression of structural proteins that are

214 ion of spontaneous cytotoxicity based on the regulation of expression of surface molecules involved i

215 We found that K-201 significantly reduced up-regulation of expression of terminal differentiation mar

216 In the current study, we investigated the regulation of expression of the A3 AR gene, focusing on

217 hese studies establish a role for Sp1 in the regulation of expression of the angiogenic factor TP in

218 of Src or Stat3 is also accompanied by down-regulation of expression of the anti-apoptotic genes, Bc

219 nes affect production of antibiotics through regulation of expression of the antibiotic-specific regu

220 RE activation by a mechanism other than down-regulation of expression of the AR.

221 Regulation of expression of the Arabidopsis COB gene fam

222 stand this regulatory system, studies of the regulation of expression of the beta-glycosidase gene (l

223 Regulation of expression of the catalytic subunit, human

224 of TCR signaling in lineage commitment, the regulation of expression of the CD4 and CD8 genes, and t

225 here that the GC reaction required biphasic regulation of expression of the cell-cycle regulator c-M

226 These data support a model of regulation of expression of the CFTR gene in which multi

227 Regulation of expression of the CFTR gene is poorly unde

228 ze of Dunaliella salina, we investigated the regulation of expression of the Chl a oxygenase (CAO) an

229 9 in the intestines of mice, including their regulation of expression of the cholesterol transporter

230 FOXO1 in these cells is also involved in regulation of expression of the critical master regulato

231 ast formation, and suggest that differential regulation of expression of the CSF-1 isoforms may influ

232 s indispensable for the post-transcriptional regulation of expression of the cyclins.

233 show its importance for the transcriptional regulation of expression of the Enterococcus faecalis pi

234 f poly(ADP-ribose) polymerase (PARP), and up-regulation of expression of the Fas ligand.

235 Regulation of expression of the fatty acid desaturase Ol

236 Regulation of expression of the gene encoding interleuki

237 ter effect was found to be accompanied by up-regulation of expression of the gene for the F-box prote

238 We have investigated the regulation of expression of the genes encoding CS1 pili

239 The regulation of expression of the genes encoding the cellu

240 We propose that loss of up-regulation of expression of the genes for glucose transp

241 Transcriptional regulation of expression of the human mitochondrial thia

242 ral nervous system often show a transient up-regulation of expression of the immediate early gene c-f

243 such as nitroxyl and peroxynitrite, after up-regulation of expression of the inducible nitric oxide s

244 indings that expand our understanding of the regulation of expression of the iscRSUA genes in Salmone

245 vity may provide a basis for the coordinated regulation of expression of the Klf4 gene in the intesti

246 that has been proposed to be involved in the regulation of expression of the LEE1 operon.

247 he specification of serotonergic neurons via regulation of expression of the Lmx1b transcription fact

248 Inhibition of RNA editing by down-regulation of expression of the mitochondrial RNA editin

249 rmation is currently available regarding the regulation of expression of the multiple protease genes.

250 one abscisic acid (ABA), are involved in the regulation of expression of the NPR1 gene of Lemna gibba

251 In parallel, we examined the regulation of expression of the PAF acetylhydrolase gene

252 port here that parS also participates in the regulation of expression of the par genes.

253 for transcriptional and posttranscriptional regulation of expression of the pIgR.

254 Both RpoN and PilR are involved in regulation of expression of the pilA gene, whose product

255 S) to experimental animals results in the up-regulation of expression of the plasma form of platelet-

256 The cell type specificity of the regulation of expression of the potent growth inhibitory

257 from our murine models revealed DMA-mediated regulation of expression of the proinflammatory cytokine

258 port that Rbm15 may function in part through regulation of expression of the proto-oncogene c-Myc.

259 at this H1b protein plays a specific role in regulation of expression of the replication-dependent hi

260 , these results revealed a difference in the regulation of expression of the TCR/CD3 complex on CD4+

261 Down-regulation of expression of the transporters for CMP-sia

262 The distinct patterns of regulation of expression of the two isoforms suggest dis

263 However, a link between regulation of expression of the two transporters in resp

264 domain of the type III receptor resulting in regulation of expression of the type III receptor at the

265 However, down-regulation of expression of these genes did not disrupt

266 The up-regulation of expression of these genes during forelimb

267 This process leads to regulation of expression of these genes.

268 However, the regulation of expression of these HAS isoforms at transc

269 transcripts, suggesting posttranscriptional regulation of expression of these latter genes.

270 The regulation of expression of these receptors occurs at th

271 ty complex class II, suggesting a coordinate regulation of expression of these various B-cell-specifi

272 anism of action of these two hormones in the regulation of expression of this gene, we cloned the 127

273 translational fusion construct to study the regulation of expression of this gene.

274 To increase our understanding of the regulation of expression of this imprinted gene, we have

275 Our data further suggest a dynamic regulation of expression of this pathway in the gastroin

276 Down-regulation of expression of trmD, encoding the enzyme tR

277 the present study, we have investigated the regulation of expression of two key heparan sulfate chai

278 ve PI 3-kinase controls cell motility by the regulation of expression of uPA through the activation o

279 ands in attenuation of new vessel growth via regulation of expression of VEGF or soluble fms-like tyr

280 rt of transcription are not required for the regulation of expression of vrg6.

281 rly, there is no information on the hormonal regulation of expression of WNK kinases.

282 for therapeutic targeting of RGS proteins by regulation of expression or allosteric modulation to per

283 ntal settings, but little is known about the regulation of expression or function of neutrophil ICAM-

284 n in the DRG may be due to glucose-driven up-regulation of expression or the result of impaired axona

285 colonic expression of meprin alpha, although regulation of expression, particularly under inflammator

286 ed to be the driver in PTC development, down-regulation of expression should contribute to the low ri

287 Regulation of expression studies showed that the malE ge

288 n chemical, functional, pharmacological, and regulation of expression studies, human alpha4 and beta2

289 nfectious cycle of B. burgdorferi, the tight regulation of expression suggests a beneficial contribut

290 e endogenous ligase by RNA interference down-regulation of expression, the added proteins were integr

291 thrombospondin 2 gene (THBS2) important for regulation of expression, the sequences of 5 kb of the p

292 extent by nucleosome prepositioning but that regulation of expression through these sites is dictated

293 is more similar in primary sequence and the regulation of expression to levansucrases of gram-negati

294 Studying the genetic regulation of expression variation is a key method to di

295 d in a series of pathways such as epigenetic regulation of expression (via TLE1 and HTATIP), biosynth

296 For the majority of the miRNAs, genetic regulation of expression was independent of the expressi

297 vated AKT resulted in rapamycin-induced down-regulation of expression, whereas low levels resulted in

298 CFTR shows tight tissue-specific regulation of expression, which is largely determined by

299 1R activity in vitro with NVP-AEW541 or down-regulation of expression with siIGF1R led to cytotoxicit

300 esence of specific mRNAs, but do not address regulation of expression within a single cell at a singl