ライフサイエンスコーパス: regulatory region

1 -coding variants in experimentally predicted regulatory regions).

2 E-boxes within the Ppargamma transcriptional regulatory region.

3 isparate outputs while utilizing this shared regulatory region.

4 cally induced removal of the auto-inhibitory regulatory region.

5 nding sequence(s) (DBS) in the TSLP promoter regulatory region.

6 necessary for DNA accessibility of a shared regulatory region.

7 peration between GR and NF-kB at a subset of regulatory regions.

8 convergent molecular changes in proteins or regulatory regions.

9 mised interactions between H4K20me3 and gene-regulatory regions.

10 by binding DNA recognition sites in genomic regulatory regions.

11 n factors that bind to stably accessible DNA regulatory regions.

12 ith chromatin accessibility and enriched for regulatory regions.

13 CNVs increase the risk of MDD by disrupting regulatory regions.

14 tecting enhancer RNAs that arise from distal regulatory regions.

15 lopedia of DNA Elements- and Roadmap-derived regulatory regions.

16 ter-enhancer interactions and demarcate gene regulatory regions.

17 t effect on pseudogene formation and loss of regulatory regions.

18 sing H3K27me3 deposition at critical genomic regulatory regions.

19 exome sequencing, and variants in non-coding regulatory regions.

20 on by altering the copy number of intergenic regulatory regions.

21 modeling deacetylase (NuRD) complex to Pdcd1 regulatory regions.

22 the Isl1/Lhx3 pair initially engage distinct regulatory regions.

23 cinomas (PDAs) and identify commonly mutated regulatory regions.

24 o TF binding, and often must be removed from regulatory regions.

25 l promoter regions, but vary in the upstream regulatory regions.

26 f rare naturally occurring mutations in gene-regulatory regions.

27 cogenic super-enhancers involving long-range regulatory regions.

28 ms, including genomic aberrations in the DNA regulatory regions.

29 or disease association on TF binding to gene regulatory regions.

30 iptional repressors acting directly on IFN-I regulatory regions.

31 enerating gene amplifications and remodeling regulatory regions.

32 to identify functional alleles in noncoding regulatory regions.

33 at somatic mutational hotspots and putative regulatory regions.

34 ere canonical LoF or non-coding in predicted regulatory regions.

35 hey are only required early to establish cis-regulatory regions.

36 thousands of SVs intersecting genes and cis-regulatory regions.

37 including several thousand prenatal-specific regulatory regions.

38 polygenic phenotypes, and enriched in active regulatory regions.

39 ciated with diseases or phenotypic traits in regulatory regions(1,7) is almost entirely attributable

40 2) and I-promoter transcription, with 3' IgH regulatory region (3' IgHRR) enhancers controlling the l

41 e constant genes and is controlled by the 3' regulatory region (3'RR) in a stimulus-dependent manner.

42 iption is controlled by the superenhancer 3' regulatory region (3'RR) that establishes long-range chr

43 mputational tools fail to reliably determine regulatory region accessibility from the analysis of the

44 causal variant in a cardiac muscle specific regulatory region activated during cardiomyocyte differe

45 lix switch dislodges the C-terminus from the regulatory region, activating the flippase.

46 thioredoxin-binding domains and the central regulatory region actively primes MKK6, a key ASK1 subst

47 m one set of targets to another, controlling regulatory region activity and gene expression as cell d

48 tifs found enriched in differentially active regulatory regions after interferon-beta stimulus, findi

49 dification, particularly methylation of gene regulatory regions, also acts to shape human brain funct

50 nt reflect the joint control of the negative regulatory region and activating phosphorylation.

51 ause it was reversed by anti-NOTCH2 negative regulatory region and anti-jagged 1 antibodies.

52 utated the SaeR-binding sequences in the hla regulatory region and determined the contribution of thi

53 induced AhR and MTA2 recruitment to the Stc2 regulatory region and induced Stc2 gene expression, whic

54 minantly (14 of 15 patients) in the negative regulatory region and Pro-Glu-Ser-Thr-rich domains, the

55 mage and functional decline enrich on kidney regulatory regions and associate with gene expression ch

56 -resistant ovarian lines identify key distal regulatory regions and associated master regulator trans

57 ranscriptional network, co-occupying cardiac regulatory regions and controlling cardiomyocyte-specifi

58 te that MntR binds to both the mneP and mneS regulatory regions and directly activates transcription

59 Integrative analysis of regulatory regions and gene expression revealed that exe

60 ated loci are enriched with newly mapped cis-regulatory regions and identify T1D-associated variants

61 DNA sequences in regulatory regions and in telomers at the ends of chromo

62 est that CAR is constitutively bound to gene regulatory regions and is regulated by exogenous agents

63 which could benefit screening, disruption of regulatory regions and multiplex base editing applicatio

64 iochemical and genetic data, we discover key regulatory regions and propose a Mec1 activation mechani

65 nism involving increased methylation of gene-regulatory regions and reduced levels of antiinflammator

66 lecular mechanisms of these NEDD4-1 and WWP2 regulatory regions and their interplay with allosteric b

67 Given that most GWAS hits are in putative regulatory regions and transcript abundance is physiolog

68 ignificantly over-represented in active gene regulatory regions and transcription factor binding site

69 on trans-activation through 5' conserved cis-regulatory regions and, in particular, whether the mamma

70 ranscriptomes limits our ability to identify regulatory regions, and in some cases can lead to misint

71 for high-throughput screening of genes, gene regulatory regions, and long noncoding RNAs.

72 -localize with tissue- or cell-type-specific regulatory regions, and we show that the resulting score

73 proteins across a set of coordinately bound regulatory regions, and which detects and quantifies pro

74 ta resources include evidence-based gene and regulatory region annotation, genome variation and gene

75 This problem is challenging because the regulatory regions are distal to the genes, with diverse

76 We show that regulatory regions are often shared between cell types o

77 Mutations in gene regulatory regions are thought to play an important role

78 Our results uncover a new critical regulatory region as a potential target for therapeutic

79 ytokines is mediated by the induction of new regulatory regions as well as the activation of primed r

80 s in PTSD patients are smaller in prefrontal regulatory regions, as well as in broader emotion and se

81 idate CRMs based on the input TF bindings at regulatory regions associated with genes of interest.

82 t aberrantly methylated CpGs are enriched in regulatory regions associated with MYC protein motifs an

83 s located in their 5' regulatory region (the regulatory region-associated microsatellite, RRAM) that

84 nscription factor activity and transcription regulatory region binding.

85 s toward detecting 'open' chromatin found at regulatory regions but are not well suited to studying c

86 repressor complex was absent from the CD133-regulatory region, but was present in the MCF-7 and prim

87 Most GWAS hits are located in cis-regulatory regions, but the underlying causal variants a

88 cific versus tissue-independent lipid-linked regulatory regions by contrasting with parallel assessme

89 1 controls chromatin accessibility at distal regulatory regions by modulating the recruitment of SMAR

90 ctions between BMAL1 enhancers and other cis-regulatory regions by RNA polymerase II chromatin intera

91 -guanines (CpGs) in gene promoters and other regulatory regions by specific demethylase(s) generates

92 esults suggest that methylation of the Nr3c1 regulatory region can contribute to the mechanisms under

93 e variants (SNVs) located in transcriptional regulatory regions can result in gene expression changes

94 an N-terminal kinase domain and a C-terminal regulatory region consisting of a approximately 100-resi

95 domain, followed by a likely posttranslation regulatory region consisting of high serine and threonin

96 A large downstream regulatory region contains a novel growth enhancer (GROW

97 Super-enhancers are an emerging subclass of regulatory regions controlling cell identity and disease

98 nding transcription factor 2 (SREBP2) at key regulatory regions controlling the expression of cholest

99 al analysis of five representatives of these regulatory regions demonstrated direct binding of OpaR i

100 Regulatory regions depleted of H3.3K4A showed histone mo

101 tivating transcription factors to shared cis-regulatory regions dictates hepatic lipid handling.

102 demonstrating that DNA methylation of the 5' regulatory region directly reduces C9orf72 expression an

103 ted variants, although located in putatively regulatory regions, do not have detectable effects on ge

104 r binding (TF) motifs in the DNA sequence of regulatory regions, enabling researchers to infer which

105 are isoform of NADK (isoform 3) lacking this regulatory region exhibits constitutively increased acti

106 he interaction of OGG1 with its substrate at regulatory regions followed by conformational adjustment

107 kbp region of the Z chromosome in a putative regulatory region for follistatin, an antagonist of the

108 have previously published DNA maps of these regulatory regions for kidney tubule cells and glomerula

109 ed with brain diseases, we defined noncoding regulatory regions for major cell types of the human bra

110 number of available human variants and added regulatory regions for many mouse cell types and develop

111 identify novel genes by determining putative regulatory regions for these and other tissues relevant

112 erences of H3K18ac and H3K27ac enrichment in regulatory regions, found a correlation between these mo

113 Computational analysis of regulatory regions from MEF2 isoform-dependent gene sets

114 dictive of behavior, and behavior-associated regulatory regions had more TF motifs.

115 Tissue-specific regulatory regions harbor substantial genetic risk for d

116 Genetic variation in regulatory regions has been connected with diseases and

117 ing mosquitoes, only a few germline-specific regulatory regions have been characterised to date and t

118 within and between CRF clades suggesting cis-regulatory regions have been conserved throughout CRF ev

119 valuable insight into the activity of these regulatory regions have been developed.

120 Genetic variants found in these regulatory regions have been shown to activate transcrip

121 -occupancy observed on PGC1beta and LPL gene regulatory regions identified.

122 sposons into the genome can disrupt genes or regulatory regions, impacting cellular function, so for

123 induced higher DNA methylation of the Nr3c1 regulatory region in adulthood, and this effect persiste

124 tes confirms the influence of the identified regulatory region in the expression of ACTN2.

125 x9 overexpression, and SOX9 binds the Notch2 regulatory region in the liver.

126 says showed that AioR interacts with the mcp regulatory region in vivo and in vitro, and the precise

127 Characterization of novel cis-regulatory regions in CD274 and PDCD1LG2 lead us to iden

128 sm chromatin accessibility to identify novel regulatory regions in complex systems.

129 ularly evident in HTS assays for identifying regulatory regions in DNA (DNase-seq, ChIP-seq, FAIRE-se

130 ociated variants are preferentially found in regulatory regions in immune cells, particularly CD4(+)

131 eferential mapping of associated variants to regulatory regions in kidney but not extra-renal tissues

132 ocal erosion of DNA methylation at oncogenic regulatory regions in mutant clones.

133 dictions, we identified SNVs within putative regulatory regions in promoters, transcription factor bi

134 sociated SNPs in the genome map to noncoding regulatory regions in T cells, but the nature of underly

135 n of G-quadruplex (G4) DNA structures in key regulatory regions in the genome has emerged as a second

136 ed and have provided novel insights into how regulatory regions in the genome interact.

137 We surveyed the Gdf5 locus for regulatory regions in transgenic mice and fine-mapped se

138 e enrichment of allergy SNPs falling in gene regulatory regions in various cells using Encode Roadmap

139 the prevalence of G4 sequence motifs at gene regulatory regions in various genomes, including in huma

140 d [Formula: see text] DNA methylation in key regulatory regions, including enhancers.

141 presented ([Formula: see text]) in important regulatory regions, including enhancers.

142 between the kinase domain and its N-terminal regulatory region independently of RAS activity.

143 Transcription sites of the full svb cis-regulatory region inserted into a different chromosome c

144 associated regions in vivo uncovers a distal regulatory region involved in Gja1 (Cx43) expression.

145 DNA methylation at Pdcd1's promoter-proximal regulatory regions is highly correlated with its express

146 we provide evidence that variation at these regulatory regions is likely to also influence gene expr

147 nes are hubs of interaction between multiple regulatory regions, likely to ensure their sustained exp

148 c risk variants in hyperacetylated noncoding regulatory regions linked to neuronal genes.

149 We fine-mapped the regulatory region located in SMIM1 intron 2 in Swedish b

150 of the expansion segment 7 (ES7), a putative regulatory region located on the surface of the 60S ribo

151 We show that in solution the central regulatory region mediates a compact arrangement of the

152 they are not designed to identify individual regulatory regions mediating risk or the genes under the

153 ct moa, to show that convergent evolution of regulatory regions, more so than protein-coding genes, i

154 cific neutralizing Ab to the Notch2-negative regulatory region (N2-NRR Ab).

155 rized by rearrangements within the noncoding regulatory region (NCCR) and 1 point mutation, S267L in

156 e, and that mutations in melanocyte-specific regulatory regions near DDB1/TMEM138 correlate with expr

157 Finally, we show that regulatory regions near epigenetic regulators are geneti

158 etic differences are restricted to two small regulatory regions near genes associated with pterin [se

159 Consistent with gene expression changes, regulatory regions near genes involved in inflammatory r

160 analysis revealed OpaR binding sites in the regulatory region of 55 carbon transporter and metabolis

161 he evening primrose Oenothera Repeats in the regulatory region of accD (the plastid-encoded subunit o

162 color variation by repeatedly recruiting the regulatory region of Agouti to modulate seasonal coat co

163 binding sites, and eight sites shared by the regulatory region of both genes.

164 We characterize an interaction between the regulatory region of CFTR and calmodulin, the major calc

165 ssions, we identify a cis-regulatory module, Regulatory region of DUO1 (ROD1), which replicates the e

166 vide significant insight into this important regulatory region of EZH2 and the first characterization

167 erential methylation in the -1058 to -587 bp regulatory region of FCGRT contributes to FcRn expressio

168 sertions of two transposable elements in the regulatory region of KNR6 can significantly enhance grai

169 hich maps to the well-characterized negative regulatory region of MEK1.

170 transcription and encompassing the noncoding regulatory region of mtDNA in human and murine cells and

171 was identified and inserted in the upstream regulatory region of PeMYB11 The insertion resulted in s

172 ide polymorphisms (SNPs) (rs12641001) in the regulatory region of SPP1 exhibited a statistically sign

173 The GusR-specific DNA operator site in the regulatory region of the E. coli GUS operon is identifie

174 ters (PR1-1, PR1-2 and PR1-3) within the PR1 regulatory region of the Escherichia coli kps capsule ge

175 to interact with genomic elements within the regulatory region of the gene encoding the differentiati

176 Polymorphisms in the regulatory region of the human neuroplastin gene (NPTN)

177 dified by dimethylation at lysine 9 at a key regulatory region of the MyoD locus.

178 racytoplasmic domain (ICD), which bound to a regulatory region of the PD-L1 locus containing a consen

179 protein CCA1 brings circadian signals to the regulatory region of the PIF4 signaling hub.

180 spontaneous sorghum mutant and suggested the regulatory region of the SbCAD2 can be a target site for

181 mechanism in which a nucleosome found in the regulatory region of the SV40 minichromosome is directed

182 weep among all hunter-gatherer groups in the regulatory region of TRPS1-primarily involved in morphol

183 ues in a highly conserved stretch within the regulatory region of yeast MTHFR to create a series of f

184 ranslocation disrupting ZMIZ1 or involving a regulatory region of ZMIZ1.

185 ow that ATF3 is bound to the transcriptional regulatory regions of >30% of differentially expressed g

186 Here, we demonstrate that SOX11 binds to regulatory regions of 2 important genes for microenviron

187 One method for identifying noncoding regulatory regions of a genome is to quantify rates of d

188 epressor IRF8, and impedes access of JunD to regulatory regions of alternative effector loci.

189 oped for directing specific guide (g)RNAs to regulatory regions of any gene of interest, to enhance t

190 lerosis is complex and that variation in the regulatory regions of associated genes may be important

191 We find that TP63 binds to transcriptional regulatory regions of ATDC and KRT14 directly, increasin

192 leotide polymorphisms (SNPs) were located in regulatory regions of candidate genes that may serve as

193 Mechanistically, Phf21b targets the regulatory regions of cell cycle promoting genes by virt

194 ifs of transcription factors in the upstream regulatory regions of differentially expressed lncRNAs,

195 estigated the presence of DNA methylation in regulatory regions of FCGRT in samples of human liver an

196 een performed, alterations in the non-coding regulatory regions of GBM have largely remained unexplor

197 ary shift were also enriched in putative cis regulatory regions of genes differentially expressed dur

198 s in methylation levels within promoters and regulatory regions of genes involved in TLR signaling in

199 esigned a 20.5 Mb array targeting coding and regulatory regions of genes with a known role in BC (n =

200 asizing how the recent identification of cis-regulatory regions of genes within the eggshell patterni

201 genomic variation, especially in non-coding regulatory regions of human genome.

202 gle-nucleotide polymorphisms mapped onto cis-regulatory regions of human MCs suggest that MC function

203 role in mitosis; however, H3S10ph also marks regulatory regions of inducible genes in interphase mamm

204 We cloned and analysed selected upstream regulatory regions of IRE1a and IRE1b, which revealed di

205 omain of Engrailed, a Drosophila TF, and the regulatory regions of its target genes.

206 ition to shared target genes, Hoxa1 binds to regulatory regions of Nanog, and conversely Nanog binds

207 Using ncdDetect, we screened non-coding regulatory regions of protein-coding genes across a pan-

208 causal variants were concentrated in active regulatory regions of relevant cell types and tended to

209 , p50 NF-kappaB promoted binding of STAT1 to regulatory regions of selected IFNgamma-dependent genes,

210 Hoxa1 also binds to regulatory regions of Sox2 (sex-determining region Y box

211 sequence-specific response elements (REs) in regulatory regions of target genes.

212 by binding to TH response elements (TREs) in regulatory regions of target genes.

213 Polymorphisms in regulatory regions of the CCL2 promoter were analyzed in

214 Screening the regulatory regions of the GATA6 gene in these patient ce

215 e activities are then interpreted by the cis-regulatory regions of the genes involved in cell differe

216 -A, VEGF-C, FGFR3, and p57 by binding to the regulatory regions of the genes.

217 disorder, variation that affects non-coding regulatory regions of the genome is likely to play an im

218 However, the regulatory regions of the genome that drive these gene e

219 ylated regions preferentially affected known regulatory regions of the genome, specifically overlappi

220 In this study, we identify regulatory regions of the KIT enhancer essential for KIT

221 ncreased beta-catenin recruitment within the regulatory regions of the Myc gene in tumor cells of the

222 BRD4 direct association to chromatin regulatory regions of the NADPH oxidase subunits increas

223 e identify and functionally characterize the regulatory regions of the P. falciparum gene PF3D7_12347

224 ers in Pparg and Ucp1 genes, and of putative regulatory regions of the Ppara gene.

225 In addition, regulatory regions of the transcription factors Tcf7 and

226 terns of histone acetylation at the proximal regulatory regions of these genes.

227 to the RAG1 promoter as well as directly to regulatory regions of transcription factors previously i

228 k loci of genome-wide significance at likely regulatory regions on chromosomes 13q22.1 (rs11841589, n

229 nsferase DNMT3B, the recruitment of which to regulatory regions on the miR-203 locus is directed by S

230 ding increase in cytosine methylation at key regulatory regions on the viral and host genomes.

231 r that classifies genome sequences as distal regulatory regions or not, given their histone modificat

232 ither: (1) residing within CRISPRi-sensitive regulatory regions, or (2) localizing in a chromatin acc

233 of aggregating motifs defined by gene exons, regulatory regions, or genome-wide sliding windows.

234 In addition to the analysis of known regulatory regions, our web tool is useful for the analy

235 Notably, VDR occupancy of the PPARgamma regulatory region precludes PPARgamma occupancy of this

236 h chromatin unpacking in the WRKY6 and PDF12 regulatory regions, primed WRKY6 expression, unprimed PD

237 We propose a model in which the central regulatory region promotes ASK1 activity via its pleckst

238 on on incident CHD; these CpGs map to active regulatory regions proximal to long non-coding RNA trans

239 a more systematic way by targeting specific regulatory regions relevant for the phenotype studied.

240 rthermore, we identify a remote upstream cis-regulatory region required for the expression of NIN in

241 Many repressed regulatory regions reside within "hyper-ChIPable" genomi

242 We identified and characterized regulatory regions responsible for CAV1, CAV2, and CAV3

243 The crystal structure of the central regulatory region reveals an unusually compact tetratric

244 ments, we adapt the self-transcribing active regulatory region sequencing (STARR-seq) strategy, a hig

245 ut enhancer screen (self-transcribing active regulatory region sequencing (STARR-seq)), we assembled

246 Here, we adapted self-transcribing active regulatory region sequencing (STARR-seq)-a technology fo

247 r RE activity using self-transcribing active regulatory region sequencing and a recently generated mo

248 n adaptation of the self-transcribing active regulatory region sequencing approach, we identified 24

249 By adapting self-transcribing active regulatory region sequencing, we evaluated the effect of

250 essed proteins contain within their proximal regulatory regions sites that are bound by SOX6 accordin

251 Variations in DNA methylation, especially in regulatory regions such as promoters and enhancers, are

252 Cytosine methylation of regulatory regions, such as promoters and enhancers, pla

253 and (iii) prioritizing/annotating non-coding regulatory regions targeting CCND1.

254 d active states differ by small changes in a regulatory region that extends up to 28 angstrom from th

255 redoxin-binding domain, along with a central regulatory region that links the two.

256 nslated region (UTR) of mRNAs is the primary regulatory region that mediates post-transcriptional con

257 lay an important role in methylation of gene regulatory regions that act as fetal-specific enhancers

258 parse in genes, reflecting the clustering of regulatory regions that act at short and long-range, whi

259 anscriptional start sites and other putative regulatory regions that are differentially accessible in

260 Strikingly, we also find a discrete set of regulatory regions that change in accessibility, consist

261 Our findings of transcribed uncharacterized regulatory regions that contain CRSs support their RNA-m

262 the noncoding genome, and found deletions in regulatory regions that contribute to disease causation.

263 sites in ASXL1 mutated MF cases are found in regulatory regions that could be associated with aberran

264 for cellular heterogeneity and can identify regulatory regions that separates cells from a complex p

265 ncer RNAs were produced from a subset of the regulatory regions, that they were critical for producti

266 hic microsatellite locus located in their 5' regulatory region (the regulatory region-associated micr

267 l enrichment of disease risk alleles on gene regulatory regions, they are not designed to identify in

268 the inheritance of nucleosome positioning at regulatory regions throughout the cell-cycle.

269 hich preferentially integrate near genes and regulatory regions; thus, insertional mutagenesis is a s

270 erminus lines a long groove in the cytosolic regulatory region to inhibit the flippase activity.

271 y binds to CCAACC core motifs present in AD1 regulatory regions to activate its expression.

272 ificant excess contribution of conserved and regulatory regions to cancer heritability.

273 imuli to chromatin, acting at super-enhancer regulatory regions to direct gene expression.

274 Linking such regulatory regions to gene promoters in disease-relevant

275 egy to sequence the entire HTR7 gene and its regulatory regions to investigate the association of com

276 gene regulation mediated by accessibility of regulatory regions to transcription factors (TFs).

277 enrichment of IPF susceptibility signals in regulatory regions) to determine putatively causal genes

278 We follow-up on adipose-specific regulatory regions under (1) genetic and (2) epigenetic

279 gs of putative tissue- or cell-type-specific regulatory regions under sequence constraint.

280 ent histone acetylation within proximal gene regulatory regions was coupled to cellular proliferation

281 Overlap with regulatory regions was further demonstrated by compariso

282 Global hypomethylation of gene-regulatory regions was observed during tumor progression

283 rk to functionally characterise the putative regulatory regions we have identified and their links to

284 are, highly sequence-conserved, IEC-specific regulatory regions, we discovered an ancient enhancer up

285 CD274 and PDCD1LG2 cis-regulatory regions were cloned from genomic DNA and asse

286 han 86.6% of these computationally predicted regulatory regions were partially corroborated by indepe

287 turnover and chromatin remodeler binding at regulatory regions, where tight regulation of Pol II act

288 parted from standard practice by identifying regulatory regions which replicate across samples and co

289 roach we were able to identify two novel cis-regulatory regions, which direct Eya1 expression to the

290 ptor (GR) and STAT3 bind to the same genomic regulatory regions, which were specifically open and unm

291 ent of TF binding motifs in a list of scored regulatory regions, while controlling for sequence bias.

292 y at active enhancers and cell-type specific regulatory regions with binding sequences of master tran

293 ssociated variants are often found in distal regulatory regions with cell-type specific behaviours.

294 ethods for WGBS are mainly designed for gene regulatory regions with multiple under-methylated CpGs (

295 2.2 x 10(-7)), and were mostly in introns or regulatory regions with predicted effects including prot

296 rious histone modifications primarily in the regulatory region, with a major nucleosome located withi

297 uals with ASD were enriched for overlap with regulatory regions, with 23/28 CNVs disrupting histone p

298 and histone methylation marks identified DNA regulatory regions within the Cd44, Cdkn1a, and Cdkn2b g

299 IP-Seq analyses of mouse tissues to identify regulatory regions within the Cyp24a1 gene locus.

300 o and in vitro analyses demonstrate that the regulatory regions within these two promoters contain th