ライフサイエンスコーパス: related gene

1 is sufficient to discover groups of disease-related genes.

2 e expression of stress-responsive and growth-related genes.

3 ctively, and downregulating EC proliferation-related genes.

4 rganoids and reduced expression of apoptosis-related genes.

5 nown Parkinson's disease genes and lysosomal-related genes.

6 single nucleotide polymorphisms in vitamin D-related genes.

7 r1 (encodes a transcription factor), and ECM-related genes.

8 ound in neurodegeneration- or carcinogenesis-related genes.

9 creased expression of IFN-beta and other IFN-related genes.

10 (Xcc) and reduces the expression of immunity-related genes.

11 mised expression of multiple immune-response-related genes.

12 rential induction of mitosis- and interferon-related genes.

13 nockout repress keratinocyte differentiation-related genes.

14 decreased expression of nodal cardiomyocyte-related genes.

15 nactivation of genes such as mismatch-repair-related genes.

16 These patients had no mutations in other PAH-related genes.

17 nd revealed changes in neuronal excitability-related genes.

18 ency in vivo activate hypothalamic autophagy-related genes.

19 h upregulation of angiogenesis and matrisome-related genes.

20 sis (VPS16), and then for other functionally related genes.

21 3K9 acetylation and activation of osteogenic related genes.

22 the activation of a constellation of defence-related genes.

23 get of rapamycin/Akt pathway (PI3K-mTOR-AKT)-related genes.

24 ry elements of many stemness- and cell cycle-related genes.

25 identification of pneumococcal pathogenesis-related genes.

26 nced expression of interferon and interferon-related genes.

27 identify deleterious mutations in ubiquitin-related genes.

28 ue to the expression of serotonin metabolism-related genes.

29 integrate multiple omics data to identify AF-related genes.

30 ted with bronchial expression of type 2 (T2)-related genes.

31 expression of serotonin receptors and immune-related genes.

32 extended longevity and represses excitation-related genes.

33 ng and differentially regulated phytohormone-related genes.

34 genes were significantly associated with ASD-related genes.

35 B to the nucleus and activation of autophagy-related genes.

36 ng networks of co-expressed and functionally related genes.

37 ns unknown why prophages integrate into tRNA-related genes.

38 nteract with each other or with known speech-related genes.

39 and H3K27me3 marks on typical dentinogenesis-related genes.

40 ated the expression of nasal epithelial cell-related genes.

41 de immune-, heat-tolerance- and reproduction-related genes.

42 ne-absent) according to expression of immune-related genes.

43 promotors and further repressed these EndMT-related genes.

44 stable upregulation of several pathogenesis-related genes.

45 ht involve in the transactivation of defense-related genes.

46 rm1 deficiency reduces the binding of brahma-related gene 1 (BRG1) to the IFNgamma receptor 2 (Ifngr2

47 re, we interrogated the roles of Brahma/SWI2-related gene 1 (BRG1, SMARCA4), the SWI/SNF catalytic su

48 tially expressed genes included cytoskeleton-related genes (actin and myosin), ECM genes (Collagens,

49 d animals subjected to RNAi knockdown of age-related genes (age-1 and daf-16).

50 mplex genomic profile and upregulated immune-related genes, allowing the possibility of immunotherapy

51 , we investigated whether variants in stress-related genes also contributed, directly and interactive

52 Cementoblast function-related gene and protein expression in the immortalized

53 identified an increased expression of myelin-related genes and a decreased expression of immediate ea

54 exhibit lower expression of SSC maintenance-related genes and are defective in their ability to diff

55 method promotes the discovery of functional-related genes and biosynthetic pathways.

56 s transgenic lines corresponding to 62 auxin-related genes and characterizing the translational repor

57 racterized by overexpression of ILC1/NK cell-related genes and downregulation of type 3 signature gen

58 constitutive upregulation of several defense-related genes and enrichment of gene ontology terms rela

59 pression of overlapping sets of glial/immune-related genes and female-biased expression of neuron-ass

60 k and identified the unexplored septic shock-related genes and functional groups.

61 nvolved in the regulation of numerous cancer-related genes and gene sets.

62 reversed expression changes in inflammatory-related genes and glutamatergic and GABAergic (gamma-ami

63 eported multiple point "mutations" in cancer-related genes and implicated selective culture condition

64 ell lines upregulated expression of stemness-related genes and induced conversion of non-CSC to CSC,

65 permissive for the expression of development-related genes and inhibitory for genes associated with n

66 transcription factor regulates neurogenesis-related genes and is associated with brain metastasis in

67 compromised expression of proliferation/Wnt-related genes and marked accumulation of ApoE.

68 provides resources to identify novel disease-related genes and pathways.

69 ated genes, ectopic expression of maturation-related genes and persistent, elevated expression of gen

70 n AD dataset, and identified several disease-related genes and processes demonstrating the usefulness

71 e involvement of cold-induced, vernalization-related genes and repressors of endodormancy release was

72 d that some subsets are enriched for disease-related genes and RNA signatures.

73 ending on significance, the following cancer-related genes and their alterations (%) were further inv

74 enomenon has been linked with several cancer-related genes and thus may play an important role in can

75 s with proteins encoded by AD- and psychosis-related genes and Vitamin D-perturbed genes.

76 e region includes several disease resistance related genes and we identified a PTI1-like tyrosine-pro

77 orrelation of miR-146a levels with NF-kappaB-related genes and with patient survival.

78 reprograms the expression of immune-response-related genes and, as a consequence, enhances the anti-t

79 he transcriptional mediator complex, cohesin-related genes, and cell cycle regulators that induce S p

80 ression of matured ventricular cardiomyocyte-related genes, and simultaneous decreased expression of

81 We evaluated the combination of cancer-related gene annotations, evolutionary conservation and

82 f synaptic transmission- and memory function-related genes are closely linked to the pathology of hea

83 different type of transcriptome in which ER-related genes are dominantly modulated by NF-Y, and impl

84 Many cell wall related genes are down regulated in mus-3 mul-1.

85 1 are up-regulated, while genome-wide cancer-related genes are down-regulated.

86 hanges in enteric neurons, show that disease-related genes are dysregulated with aging, and identify

87 eveal that auxin-responsive genes and growth-related genes are highly activated by epidermal, but not

88 frequencies of these and other functionally related genes are largely unknown, particularly in cance

89 Upon contact, several chemosensory related genes are repressed, especially odorant binding

90 ), coding and splice-site regions of 10 AMD-(related) genes (ARMS2, C3, C9, CD46, CFB, CFH, CFI, HTRA

91 ifferentiation and reduced expression of Wnt-related genes, as measured by real-time PCR and western

92 and expression of excitation- and inhibition-related genes, as well as genes specific to voltage-gate

93 rther revealed that NR2F2 acts with ERG (ETS-related gene) at many of these sites to drive vein-speci

94 the posttranscriptional control of autophagy-related genes (ATGs) in the intestinal epithelium.

95 A methylation changes associated with cancer-related genes become more pronounced at invasive breast

96 tivator3 (CAMTA3) is a repressor of immunity-related genes but an activator of cold-induced or genera

97 Ss/MPNs) harbor somatic mutations in myeloid-related genes, but still, current diagnostic criteria do

98 tings might be used to help identify disease-related genes by guiding the development of background-m

99 evelop an approach to identify additional AF-related genes by integrating multiple omics data.

100 capability of AAV2.retro to deliver disease-related gene cargo to biologically-relevant NHP brain ci

101 ng the complement factor H (CFH, FH) and CFH related genes (CFHR1-5) are major determinants of AMD su

102 l-learning, we demonstrate that functionally related genes cluster by morphotypic similarity and that

103 The fellutamide gene cluster and related gene clusters are recognized as relatives of the

104 ase and germline mutations in non-BRCA1/2 HR-related genes (cohort 1) or somatic mutations in these g

105 along with upregulation of myelin-synthesis related genes, collectively resulting in functional myel

106 bited a spectrum of EMT phenotypes, with EMT-related genes concomitantly expressed with the activatio

107 to coastal ecotype I in Fe physiology and Fe-related gene content, suggesting populations from these

108 that a large set of intellectual disability-related genes contribute to ADHD risk through effects of

109 anscription of two dozen defence- and health-related genes correlates a nanoscale Cu-enhanced innate

110 ind hundreds of variants within known cancer-related genes detectable only through long-read sequenci

111 carbohydrate, lipid-metabolism, and defence-related genes, differentially expressed in mycorrhiza un

112 quent aberrant expression of multiple biotin-related genes, disrupting both carboxylase and mitochond

113 eficiency dysregulates expression of meiosis-related genes (e.g. Sycp3, Rad51, Ybx2) and a variety of

114 ch was identified in TP53/cell cycle pathway-related genes (eg, TP53 and MDM2) in 72%, genes encoding

115 on-specific (ETS) transcription factors, ETS-related gene (ERG) and Friend leukemia integration 1 (FL

116 hat the erythroblast transformation-specific related gene(ERG) exerts an important role in maintainin

117 Moreover, AS-related genes exhibited rhythmic AS and APA regulation,

118 howed enhanced stem cell and axonal guidance related gene expression (Bmp2, GDNF, and Shh) in Acomys

119 showing increased inflammation and fibrosis related gene expression (Serpine 1, Plau, and Timp1) in

120 disorders, we investigated whether serotonin-related gene expression across the brain's emotion regul

121 ells, and DSP regulates extracellular matrix-related gene expression and cell migration, which is rel

122 ates, i.e. pheophorbide a Both jasmonic acid-related gene expression and jasmonic acid precursors spe

123 he loss of DSP enhances extracellular matrix-related gene expression and promotes cell migration, whi

124 nd for regulation of jasmonic acid and auxin-related gene expression as well as expression of develop

125 inib suppresses HIV-1-driven aberrant cancer-related gene expression at the integration site.

126 regulation of DNA metabolism and cell-cycle-related gene expression during nitrogen (N) deprivation,

127 tically enhance the increase in reprograming-related gene expression in mouse fibroblasts when combin

128 IAP also upregulated autophagy-related gene expression in small intestine in mice.

129 n and recapitulates the cell differentiation-related gene expression profile by suppressing Wnt pathw

130 This unique age-related gene expression profile in the red sea urchin ne

131 scriptome analysis revealed distinct disease-related gene expression profiles depending on anatomical

132 Inflammation-related gene expression showed the most pronounced varia

133 regulated Oxidative Phosphorylation (OxPhos) related gene expression, accompanied by compromised mito

134 al growth, cell morphology and lysis, cancer-related gene expression, and metabolomics.

135 th prior maps of aerobic glycolysis (AG), AG-related gene expression, postnatal cortical surface expa

136 , including copy number variation and immune-related gene expression, we demonstrate our method's uti

137 s and increased senescence- and pathogenesis-related gene expression.

138 d HPV18 E7 unable to repress differentiation-related gene expression.

139 s to determine their effect on mitochondrial-related gene expression.

140 genic, hypertrophic, rRNA and osteoarthritis related gene expression.

141 on prolonged treatment, modulated rejection-related gene-expression patterns.

142 A improved endoplasmic reticulum (ER) stress related gene expressions, fasting glucose levels, insuli

143 CTL evasion, and show that the lipid-droplet-related gene Fitm2 is required for maintaining cell fitn

144 Five polyomavirus genes and seven immune-related genes (five associated with BKVN and two associa

145 ession levels of immunity and detoxification-related genes, food collection, weight gain, worker and

146 ts, molecular ages, defined by 68 and 76 age-related genes for two brain regions respectively, were p

147 BLApn knockout of a second learning-related gene, Fos, also increased excitability and impai

148 Copy number expansion of auxin-related genes from duplications and elevated auxin produ

149 ilepsy, heart disease or respiratory disease-related genes from previous published reports and compar

150 of protein-coding regions of cancer-biology related genes (gHFI) determines which and how many somat

151 Glucocorticoid-induced TNFR family related gene (GITR) is a member of the TNFR superfamily

152 ociation between BPA-responsive genes and AD-related genes has not been thoroughly investigated.

153 More generally, these examples suggest why related genes have been maintained by evolutionary force

154 heterologously expressed human ether a-go-go-related gene (hERG) 1a/1b channels, which more closely r

155 The human ether-a-go-go-related gene (hERG) encodes the channel that conducts th

156 Human ether-a-go-go-related gene (hERG) encodes the pore-forming subunit of

157 ropensity to inhibit the human ether-a-go-go-related gene (hERG) potassium ion channel whose inhibiti

158 The human ether-a-go-go-related gene (hERG1) channel conducts small outward K(+)

159 promiscuous drug target human ether-a-go-go-related gene (hERG1), the pore-forming domain of the del

160 s of elevated expression of ALDH1A1 and stem-related genes, high aldehyde dehydrogenase activity, and

161 We performed targeted resequencing of HDL-related genes in 200 patients admitted to an emergency d

162 dentified a set of glucocorticoid and immune-related genes in association with parental Holocaust exp

163 rential expression of known root development-related genes in atdro1 mutants.

164 e also decreasing expression of inflammation-related genes in cytokine-treated cells.

165 referentially suppresses expression of clock-related genes in high throughput gene expression studies

166 Here we report that POU3F2 regulates 42 SCZ-related genes in knockdown and RNA-sequencing experiment

167 The arrangement of functionally-related genes in operons is a fundamental element of how

168 aling and modulates the expression of immune related genes in peripheral leukocytes and immune-relate

169 alysis showed downregulation of multiple WNT-related genes in primary culture cells from ampullary ad

170 owed superiority in identifying functionally related genes in real gene expression datasets.

171 coordinate the expression of photosynthesis-related genes in response to growth and environmental ch

172 n neuronal projection and synaptic structure related genes in stereotypy mice.

173 Our results support a role for adipogenesis-related genes in subcutaneous adipose tissue sex differe

174 increased expression of particular invasion-related genes in switched parasites, as well as a large

175 reens revealed positive selection on hearing-related genes in the ancestral branch of bats, which is

176 In vitro validation confirmed key diabetes-related genes in the context of immunosuppression.

177 itutive overexpression of several resistance-related genes in the resistant genotype compared to the

178 wth-regulating mechanisms acting through IGF-related genes in ways that are not reflected in measured

179 ability using a gene panel with 480 epilepsy-related genes including all GABAA receptor subunit genes

180 d higher-level expression of many osteoblast-related genes including osteopontin and osteocalcin, whi

181 ntry associated with induction of cell cycle-related genes (including cyclin D1), and up-regulation o

182 We found selection and loss of immunity-related genes (including pro-inflammatory NF-kappaB regu

183 790M mutation, chromosomal instability (CIN) related genes, including AURKA and TP53 alterations, wer

184 increased expression of extracellular matrix-related genes, including MMP7 and MMP9.

185 upregulation of transcription- and chromatin-related genes, including the histone acetyltransferases

186 differentiation-related and class switching-related genes, indicating a potential role of IL-21 in m

187 des various ways to retrieve defense systems related genes information and visualize them with multif

188 (RNAP) to control the expression of flagella-related genes involving bacterial motility and chemotaxi

189 utophagy pathways, cytoskeletal elements, AD-related genes, ionotropic and metabotropic glutamate rec

190 d in macaque, and that expression of disease-related genes is largely conserved between the two speci

191 the H3K27me3 levels in chromatin of ripening-related genes is negatively correlated with accumulation

192 4R) and Th22/Th17 (IL36G, CCL20, and S100As)-related genes, largely lacking significant Th1-skewing.

193 ies (e.g. carbonic anhydrase, anti-oxidative related genes), many of which show gametophyte-specific

194 Alteration of CAMs-related genes may be specific pathological markers for t

195 netic line differences in expression of eIF2-related genes may contribute to their differential resis

196 These common stress-related genes may represent particularly attractive ther

197 cemaker neurons express a rich set of immune-related genes mediating their interaction with the micro

198 NR3C1 and consequent changes in other stress-related genes might be fundamental in the pathophysiolog

199 atic subclones had greater activation of EMT-related gene networks than parental Suit2 cells, and for

200 nt downregulation of key MAPK and plasticity-related genes, notably of EGR1/Zif268 and Arc/Arg3.1, su

201 Meiosis- and RNAi-related genes often coamplify on recently formed X and Y

202 We further establish that cancer-related genes on Chromosome 21 are up-regulated, while g

203 nhancers were associated with chondrogenesis-related gene ontology (GO) terms.

204 s, synapse assembly, cell proliferation, and related Gene Ontology categories.

205 s mutations in homologous recombination (HR)-related genes other than BRCA1/2.

206 Notably, compared with loss of the closely related gene p130, loss of p107 results in fewer but lar

207 ound significant downregulation of autophagy-related genes particularly, autophagosome complex.

208 r profiling disclosed that neurodegenerative-related gene pathways altered in PD can be reversed usin

209 evels and dysregulation in brain development-related gene pathways in the fetal brains of MIA mice.

210 entially methylated genes, many within auxin-related gene pathways.

211 ed strong regulation of several pathogenesis-related genes, pattern recognition receptors, and resist

212 of-function mutation in the lipid-metabolism-related genes pcsk9, apoc3, and angptl3 would improve ca

213 NH2-encoded Kv11.1 hERG (human ether-a-go-go related gene) potassium channel is a critical regulator

214 nsitive inducible genes such as pathogenesis-related gene PR-1, glutathione-S-transferase, phospholip

215 Variants in ubiquitin-related genes, previously implicated in autoinflammatory

216 rugs by their likelihood of targeting ageing-related gene products in humans.

217 dy significantly extended the chemosensation-related gene profiles (particularly, OBPs and ORs) in si

218 otent pro-inflammatory and neurodegeneration-related gene program, evidenced by increased neurotoxici

219 the transcription of downstream lipogenesis-related genes, proliferation of tumour cells, and tumori

220 ar endothelial growth factor-D (VEGF-D), ETS-related gene protein (ERG), and insulin-like growth fact

221 the panel, combining biomarker proteins ETS-related gene protein (ERG), insulin-like growth factor-1

222 mRNA expression of the osteoclast activator-related gene, receptor activator of nuclear factor kappa

223 ), were analyzed for inflammation and kinome-related gene regulation.

224 Distinct Fe-related gene repertories of HNLC ecotypes CRD1 and CRD2

225 to VDR-knockdown mitochondrial function and related gene-set expression is impaired.

226 aged to improve the identification of cancer related gene sets by discovering groups with complementa

227 riched the cell proliferation and cell cycle related gene sets in GSEA.

228 gulation of matrisome, cell cycle and immune related gene sets in Lcn2(-/-) mice exposed to CCl(4), a

229 Strikingly, interferon- and inflammatory-related gene sets were enriched in cell lines exhibiting

230 ion of inflammatory and extracellular matrix related gene sets.

231 strate that the majority of seed-dehydration-related genes showed similar expression patterns in leav

232 ers, we observed induction of a strong IL-17-related gene signature in the vagina during estrogen-dep

233 rized by a strong enrichment in inflammation-related gene signatures, elevated expression of pro-infl

234 and suppressed expression of numerous cancer-related gene signatures.

235 knockout of the mitochondrial fusion-fission-related gene solute carrier family 25 member 46 (Slc25a4

236 ulates the expression of Th1 differentiation-related genes such as Ifng and Il12rb2.

237 ed recurrent alterations of Burkitt lymphoma-related genes such as MYC, ID3, and DDX3X and homozygous

238 a number of development and stress response-related genes such as the RNA silencing effector gene AR

239 ion in the expression of cellular senescence-related genes, such as beta-galactosidase, p21, p53, and

240 is a transcriptional repressor of flowering-related genes, such as FLOWERING LOCUS T (FT), FLOWERING

241 Pathogenesis-related genes, such as genes encoding chitinases and PR1

242 r that reduced the expression of contraction-related genes, such as MYH (myosin heavy chain) and trop

243 ingly, the transcription level of resistance related genes, such as PAL and PBZ1, is inhibited in pla

244 sion which might be mediated by preeclampsia-related genes, suggesting a possible association between

245 e leads to the transcriptional modulation of related genes, termed adapting genes.

246 cs approach identified many more relevant AF-related genes than using AFGen 2018 GWAS alone (1931 ver

247 re important for the regulation of virulence-related genes that control biofilm formation, streptolys

248 was correlated with tumour microenvironment-related genes that encode proteins involved in extracell

249 tantly related cell types such as the immune-related genes that were similarly expressed in immune ce

250 mRNA target interactions, with angiogenesis-related genes the most enriched.

251 fewer astrocyte, oligodendrocyte and neuron-related genes, the notable exception being a cluster of

252 essing multidrug resistance genes and cancer-related genes, thereby rendering cancer cells vulnerable

253 We identified p75NTR and related genes through extensive data mining of a PubMed

254 manipulating Wnt signalling, suggesting Wnt-related genes to be downstream effectors of AnxA8.

255 pplied a targeted sequencing of 37 TCA-cycle-related genes to DNA from 104 PPGL-affected individuals

256 d genome-wide splicing alterations of cancer-related genes to promote malignancy.

257 oped a panel of knockouts (KOs) of autophagy-related genes to test which components of the canonical

258 perform eQTL analysis for 406 breast cancer-related genes to train race-stratified predictive models

259 Among those SCZ-related genes, TRIM8 (Tripartite motif containing 8) is

260 content and expression levels of senescence-related genes under -N conditions.

261 Analyses of AKT-related genes using microarray, immunoblotting, and real

262 sion of ACE2 and other coronavirus infection-related genes using microarray, RNA sequencing, and 10x

263 tes in Lithuania, uncover potential diabetes-related gene variants, and prospectively introduce preci

264 The expression of Heph, Cp, and other iron-related genes was examined in astrocytes and oligodendro

265 Differential expression of carrageenan-related genes was found primarily between gametophytes a

266 Further, the expression of suberin-related genes was induced by ShMYB78 heterologous expres

267 which distinct down-regulation of cell cycle-related genes was observed.

268 Expression of some of the related genes was, however, different between the region

269 tility of zebrafish for the analysis of CPHD-related genes, we analyzed the effect of OTX2 loss of fu

270 embrane proteins, the WNT pathway and cancer-related genes, we identified key molecules in the select

271 actions and the expression of EC dysfunction-related genes, we suppress the LINC00607 RNA.

272 timates corroborated the finding that immune-related genes were activated in the LV but not in the RV

273 (FASN and CYP7A1), and organ growth (IGF-I) related genes were affected by the dietary treatments, w

274 in glucocorticoid signaling and inflammation-related genes were associated with alcohol use behaviors

275 y leading to cuticle formation and that NOG2-related genes were co-opted into the lignin biosynthesis

276 otide polymorphisms (SNP) in neuroplasticity-related genes were compared between asthma and healthy p

277 In DLPFC gray matter, 41% of mitochondrial-related genes were differentially expressed in the schiz

278 in metabolism-related and signalling pathway-related genes were differentially expressed in the siR10

279 C(4)-related genes were down-regulated and subsequently fully

280 In contrast, inflammation-related genes were down-regulated in the RV and while ox

281 er sequences of five paclitaxel biosynthesis-related genes were isolated.

282 Four capsidiol-related genes were selected for RT-qPCR analysis, two 5-

283 and one duplication) involved in 10 disease-related genes were selected for validation by using quan

284 Obesity-related genes were significantly enriched among 103,466

285 Ripening-related genes were significantly upregulated in SlLHP1b

286 encing of the 3 subsets revealed that G-MDSC-related genes were specifically upregulated in mature ne

287 ER stress-related genes were up-regulated in the hypothalamus of n

288 All immunity-related genes were upregulated in the bumblebees inocula

289 unity were downregulated, while inflammation-related genes were upregulated.

290 This supports a broad role for seed-related genes, where many are involved in typical drough

291 and five high-dimensional datasets of ageing-related genes, where the predictors are Gene Ontology te

292 y involves type I interferons and interferon-related genes, whereas the WT and DUBmut viruses more br

293 d upregulation of TGF-beta and Wnt signaling-related genes, which are known to play an important role

294 terns varied greatly among neuroinflammatory-related genes, which are known to play roles in alcohol

295 of Snf2h results in dysregulation of meiosis-related genes, which causes failure of maturation-promot

296 However, multiple invasion-related genes with complementary and overlapping functio

297 ws accurate consensus generation for closely related genes with nanopore sequencing.

298 ual with MCD and a comprehensive list of MCD-related genes with their associated phenotypes.

299 transcription of various mTOR and metabolism-related genes within effector CD4(+) T cells.

300 n example of this is the analysis of disease-related genes within sub-populations of blood or biopsie