ライフサイエンスコーパス: relaxant

1 O2 and VCO2 seen without the use of a muscle relaxant.

2 tor of muscle function and works as a muscle relaxant.

3 ed with rocuronium, a nondepolarizing muscle relaxant.

4 ete as predicted by its efficacy as a muscle relaxant.

5 or is prostacyclin (PGI(2)), a smooth muscle relaxant.

6 abor is prostacyclin (PGI2), a smooth muscle relaxant.

7 r to labor, prostacyclin, is a smooth muscle relaxant.

8 xamine cisatracurium, a commonly used muscle relaxant.

9 line receptors are clinically used as muscle relaxants.

10 impaired by volatile anesthetics and muscle relaxants.

11 tic and anti-inflammatory therapy and muscle relaxants.

12 ational anaesthetics and depolarising muscle relaxants.

13 to metabolize specific analgesics and muscle relaxants.

14 volatile anesthetics or depolarizing muscle relaxants.

15 scription proton-pump inhibitors, and muscle relaxants.

16 identifying cross-reactivity between muscle relaxants.

17 tion of vasodilators and other smooth muscle relaxants.

18 atric airway has reduced the need for muscle relaxants.

19 ere highly protected from water-soluble spin relaxants.

20 common medication classes were smooth-muscle relaxants (16 trials), bulking agents (13 trials), proki

21 ings to respond to the endothelium-dependent relaxant acetylcholine, both during in vitro hyperglycem

22 that are probably independent of its muscle-relaxant action.

23 ith similar in vitro potency as 4 as well as relaxant activity on bladder smooth muscle in vivo when

24 lgesic agent without centrally acting muscle relaxant activity.

25 The pericyte relaxant adenosine increased capillary diameter by 21% a

26 bitor), but not hydralazine (a smooth muscle relaxant), ameliorated colitis in RenTgMK mice, although

27 metabolites or analogs, anesthetics, muscle relaxants, amphetamines and stimulants, benzodiazepines,

28 viorally, SH-I-048A induced sedative, muscle relaxant and ataxic effects, reversed mechanical hyperal

29 ate that PDE4D plays a key role in balancing relaxant and contracting cues in airway smooth muscle, s

30 2 following the administration of the muscle relaxant and the observation that turning a patient into

31 constructs were able to relax in response to relaxants and contract in response to contractile agents

32 Specific relaxants and doses can be chosen to suit the clinical c

33 d between the sexes, particularly for muscle relaxants and opioids.

34 t antimicrobial, vasodilating, smooth muscle relaxant, and growth factor stimulating effects.

35 gical needs should dictate the use of muscle relaxants, and alternatives to their use should be consi

36 istamines, antihypertensives, antimalarials, relaxants, and bronchodilators.

37 ement strategy that avoids sedatives, muscle relaxants, and physical restraints, and allows liberal b

38 rounding ECT, cardiac effects, use of muscle relaxants, and the consent process.

39 te produces the sedative, anxiolytic, muscle relaxant, anticonvulsant and cognition-impairing effects

40 e discovery of the nonsedating potent muscle relaxant, antiinflammatory, and analgesic agent (E)-2-(4

41 paper describes the synthesis and the muscle relaxant, antiinflammatory, and analgesic structure-acti

42 steroidal anti-inflammatory drugs and muscle relaxants are a very effective combination for the effec

43 acting and low doses of medium-acting muscle relaxants are appropriate for the typically short period

44 Smooth-muscle relaxants are beneficial when abdominal pain is the pred

45 Skeletal muscle relaxants are effective for short-term pain relief in ac

46 Muscle relaxants are still indicated for intubation and procedu

47 c drugs (inhalational anesthetics and muscle relaxants) are described.

48 which is currently FDA approved as a muscle relaxant, as a safe and novel treatment of EA2.

49 olytic activity but was devoid of the muscle relaxant/ataxic effects of "classical" 1,4-benzodiazepin

50 To understand this potential contractile-relaxant autoregulatory mechanism, production of cardiac

51 least 30 case reports have linked the muscle relaxant baclofen to encephalopathy in patients with chr

52 discovery of the GABA(B) agonist and muscle relaxant baclofen, there have been substantial advanceme

53 d gamma-cyclodextrin and the first selective relaxant binding agent), forms very tight complexes in a

54 Selective relaxant binding agents offer a new approach for the rev

55 Obesity impairs the relaxant capacity of adipose tissue surrounding the vasc

56 nce of membranes and of a water-soluble spin relaxant (chromium oxalate) has been developed to determ

57 ne; the antiemetic benzquinamide; the muscle relaxant cyclobenzaprine; the analgesic nefopam; and the

58 receptor (RYR) channels, the skeletal muscle relaxant dantrolene has proven to be both a valuable exp

59 mployed for a formal synthesis of the muscle relaxant Dantrolene in excellent yields.

60 The skeletal muscle relaxant dantrolene inhibits the release of Ca2+ from th

61 In tracheal intubation, the use of muscle relaxants decreases laryngospasm.

62 ound nitroxide by a membrane-impermeant spin relaxant depends on the distance (up to tens of angstrom

63 Airway relaxant dose-response curves were constructed to measur

64 e and factors affecting the choice of muscle relaxant drugs in pediatric anesthesia.

65 lled trials concluded that the smooth muscle relaxant drugs tamsulosin and nifedipine assisted stone

66 targeted by a variety of anticonvulsant and relaxant drugs.

67 nic and anticholinergic/direct smooth muscle relaxant drugs.

68 t sites in the MRF would be effective muscle relaxants during pregnancy, prior to the fall in progest

69 drugs has reduced the requirement for muscle relaxants during surgery.

70 overy of the potent, centrally acting muscle relaxant (E)-2-(4,6-difluoro-1-indanylidene)acetamide, 1

71 benzodiazepines, gabapentinoids, and muscle relaxants each contributed substantially to the increase

72 m lacking the acidic C terminus had the same relaxant effect as wild-type telokin, whereas the C-term

73 nly terbutaline showed a differential airway relaxant effect between proximal and distal airways, as

74 This relaxant effect contributed to a beta-adrenoceptor-media

75 phospholamban phosphorylation and a de novo relaxant effect following beta(2)-AR stimulation, conver

76 The relaxant effect is thought to be due primarily to stimul

77 horylation by CaMKII and is essential to the relaxant effect of beta-adrenergic stimulation.

78 The relaxant effect of beta-receptor stimulation was absent

79 ontribution of myofilament properties to the relaxant effect of beta-stimulation may be of greater si

80 Therefore, ICCs and SMCs jointly mediate the relaxant effect of enteric NO.

81 hich is independent of, but additive to, the relaxant effect of Ser(16) phosphorylation, resulting in

82 hway providing a molecular mechanism for the relaxant effect of the hormone.

83 in-converting enzymes (ACE), and direct vaso-relaxant effect or calcium channel modulation.

84 iod (n = 10), suggesting that some of Epac's relaxant effect relies upon vascular cell hyperpolarizat

85 phosphorylation of telokin up-regulates its relaxant effect.

86 pathway, resulting in positive inotropic and relaxant effects in the heart.

87 d increased sensitivity of the muscle to the relaxant effects of 8-Br-cyclic guanosine monophosphate

88 -K channels appear to indirectly mediate the relaxant effects of a number of agents, activators that

89 sium channel mediates vascular smooth muscle relaxant effects of barks used in Native American folk m

90 d sensitivity of airway smooth muscle to the relaxant effects of endogenous NO.

91 After measurement of the contractile and relaxant effects of epinephrine (10 micromol/L) or zinte

92 in the study suggests that the smooth muscle relaxant effects of heptanol may be non-specific and unr

93 To evaluate the relaxant effects of other TLRs.

94 epleted of its endogenous telokin, and their relaxant effects were mutually potentiated.

95 In addition to its vascular relaxant effects, cAMP is known to protect endothelial c

96 ctor through which beta-agonists exert their relaxant effects.

97 The endothelium relaxant factor nitric oxide is well known to mediate mi

98 n are NSAIDs, acetaminophen, skeletal muscle relaxants (for acute low back pain), and tricyclic antid

99 that NSAIDs, acetaminophen, skeletal muscle relaxants (for acute low back pain), and tricyclic antid

100 evaluate the corpus cavernosum smooth muscle relaxant function in a murine model that displays intrav

101 y of GRK2/3 regulation of procontractile and relaxant G-protein-coupled receptors in ASM.

102 As the quality of currently available relaxants has improved, the need to combine relaxants to

103 e effects of the intubating dose of a muscle relaxant have worn off.

104 Treatment with a muscle relaxant impairs mouth opening, supporting the hypothesi

105 de, SMP) was recently identified as a muscle relaxant in the starfish Patiria pectinifera.

106 etic drugs have influenced the use of muscle relaxants in children.

107 a family of neuropeptides that act as muscle relaxants in echinoderms.

108 nce for efficacy was shown for smooth-muscle relaxants in patients with abdominal pain as the predomi

109 have reduced or obviated the need for muscle relaxants in pediatric anesthesia.

110 -1 receptor antagonist in sepsis, and muscle relaxants in severe acute respiratory distress syndrome

111 may improve upon currently available muscle relaxants in terms of rapid onset, short duration, and m

112 sults suggest the conservation of an ancient relaxant-inflammatory response of perturbed fluid-carryi

113 bolished in all regions by the smooth muscle relaxants isoproterenol (1 microM), nicardipine (1 micro

114 re incriminated: antibiotics (49.6%), muscle relaxants, latex and anesthetics (15%), nonsteroidal ant

115 To gain insight into pro-relaxant mechanisms effected by TAS2Rs, we employed an u

116 l anti-inflammatory drugs or skeletal muscle relaxants (moderate-quality evidence).

117 ing that other nonadrenergic, noncholinergic relaxant neurotransmitters lack influence under baseline

118 s ratio, 1.52; P=0.005), preoperative muscle relaxant (odds ratio, 1.52; P<0.001) or benzodiazepine (

119 maxi-K opener was identified as an effective relaxant of rabbit corporal smooth muscle and shown to b

120 , acetaminophen, opioids, or skeletal muscle relaxants, often in combination.

121 ndent relaxation, whereas responses to other relaxant or contractile factors were normal.

122 and contraction, whereas responses to other relaxant or contractile factors were normal.

123 ction, acetaminophen (with or without muscle relaxants or NSAIDS), topical capsaicin, biofeedback, co

124 oids, anti-convulsant drugs, skeletal muscle relaxants, or corticosteroids) compared with another ana

125 lementation (decreases in concomitant muscle relaxants orders [RR, 0.94; 95% CI, 0.89-1.00], initial

126 g measures (ie, decreased concomitant muscle relaxants orders, initial and renewal opioid orders, and

127 lgesics, antiinflammatory agents, and muscle relaxants) (P< 0.001) and used less physical therapy (0.

128 lock with the reversible, competitive muscle relaxant, pancuronium.

129 Pronounced contractile and relaxant parasympathetic reflex responses could be evoke

130 nse to SCD-associated hypoxia activates CSM "relaxant" pathways; excessive activation of these pathwa

131 Administration of a vascular smooth muscle relaxant prevented onset of myocardial necrosis.

132 diseases, we here tested bitter tastants for relaxant properties and profiled Tas2r expression in the

133 oforms is thought to determine smooth muscle-relaxant properties and unique responses to signaling pa

134 play a key role in the anxiolytic and muscle-relaxant properties of benzodiazepine-type drugs; instea

135 NO alters contractile and relaxant properties of the heart.

136 ic technique incorporating a nondepolarizing relaxant provides the best intubating conditions with th

137 significant inverse correlation between ACh relaxant response and 3-NT immunoreactivity.

138 rtrophy (LVH), this endothelium-dependent LV relaxant response is impaired despite a preserved respon

139 In contrast, relaxant response to acetylcholine (ACh) was decreased s

140 modifications of contractile properties and relaxant response to acetylcholine of femoral artery in

141 h) was decreased sixfold without a change in relaxant response to sodium nitroprusside.

142 A similar restoration of relaxant response to substance P was observed in the pre

143 All contractile and relaxant responses evoked by these stimuli were absent i

144 e receptor-mediated positive contractile and relaxant responses in cardiac myocytes.

145 hock exhibited reduced endothelium-dependent relaxant responses in response to acetylcholine.

146 significantly improved endothelium-dependent relaxant responses of aortic rings.

147 ibitor 1 J completely reversed the increased relaxant responses to acetylcholine and EFS in PHZ mice.

148 Increased corpus cavernosum relaxant responses to acetylcholine and EFS were observe

149 to play a significant role in contractile or relaxant responses to any pharmacomechanical or electrom

150 Contractile and relaxant responses to capsaicin and resiniferatoxin were

151 Relaxant responses to EFS were assessed at frequencies f

152 or deferoxamine (500 micromol/L) restored LV relaxant responses to the NO agonists bradykinin (10 nmo

153 survival rates and vascular contractile and relaxant responses were recorded.

154 ted animals showed decreased contractile and relaxant responses, and inosine pretreatment (but not po

155 cells leading to changes in contractile and relaxant responses, proliferation, and the ability of sm

156 dotoxemia and impaired endothelium-dependent relaxant responses, to which MPO-deficient mice were res

157 heir contractility to ACh and impaired their relaxant responsiveness to isoproterenol.

158 sthmatic-like changes in ASM constrictor and relaxant responsiveness, and that these effects were abl

159 proasthmatic changes in ASM constrictor and relaxant responsiveness.

160 Only nondepolarizing muscle relaxants should be used in patients who are at risk for

161 During ambulatory anesthesia, muscle relaxants should be used judiciously because of their im

162 e increased prescriptions of skeletal muscle relaxants (SMRs) for chronic pain, but the efficacy of l

163 n anesthetics and/or the depolarizing muscle relaxant succinylcholine in malignant hyperthermia-susce

164 by their increased sensitivity to the muscle relaxant succinylcholine.

165 e electron paramagnetic resonance (EPR) spin relaxant techniques.

166 adenylate cyclase and a much more effective relaxant than CGRP.

167 nd galantamine, and new drugs such as muscle relaxants that may be repurposed for treating nicotine a

168 re treated with hydralazine (a smooth muscle relaxant), the blood pressure was normalized but the lun

169 Locally delivered ureteral relaxants therefore may improve ureter-related condition

170 n proposed as a novel class of smooth muscle relaxants to combat excessive contraction in the airways

171 relaxants has improved, the need to combine relaxants to minimize the incidence and severity of thei

172 opioids, sedative-hypnotics, skeletal muscle relaxants, tricyclic antidepressants, and first-generati

173 tion attempts and laryngoscopic view, muscle relaxant use is an independent predictor of complication

174 r previous opioid, benzodiazepine, or muscle relaxant use, 8.9% of the remaining cohort had POU.

175 omuscular blocking agents (NMBAs) are muscle relaxants used to assist mechanical ventilation but lead

176 s and membrane-permeant and -impermeant spin relaxants, we have determined the orientation of C2cPLA2

177 Potent relaxants were evaluated in vivo in a rat model of bladd

178 Dantrolene is a skeletal muscle relaxant which acts by inhibiting intracellular Ca(2+) r

179 Because the muscle relaxant zoxazolamine is a known substrate for CYP1A2, w