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1 different end products; duplex linear DNA or relaxed circular DNA.
2 t make contributions during the synthesis of relaxed circular DNA.
3 on of circularized plus-strand DNA generates relaxed circular DNA.
4 more readily to supercoiled DNA than to the relaxed circular DNA.
5 ase efficiently converts the linear DNA into relaxed circular DNA.
6 tor sites, are required for the synthesis of relaxed-circular DNA.
7 old decrease in the level of the full-length relaxed circular DNA, a 4- to 5-fold decrease in the plu
9 V reservoir (circular covalently closed DNA, relaxed circular DNA, and pregenomic RNA: 5.6, 2.4, and
10 hy this region also enhances supercoiling of relaxed circular DNA by the didomain and circularization
11 s formed by the repair of lesion-bearing HBV relaxed circular DNA delivered by the virions to hepatoc
13 ntermediate, termed pregenomic RNA, into the relaxed circular DNA genome, which is subsequently conve
14 in-specific PCR assays and (i) finding WHVNY relaxed circular DNA in the serum samples collected from
16 activity of RecG but not for RuvAB, whereas relaxed circular DNA is a poor cofactor for RecG but an
17 imals, the kinetics of accumulation of serum relaxed circular DNA of WHV demonstrated that the virion
18 cytolytically, probably by eliminating their relaxed circular DNA precursors and perhaps by destabili
21 ere that viral capsids, single-stranded DNA, relaxed circular DNA (rcDNA) and covalently closed circu
22 s was found in a few samples; and (ix) serum relaxed circular DNA (rcDNA) and rd-RNAs should be quant
23 f PFA to allow the synchronized synthesis of relaxed circular DNA (rcDNA) and subsequent conversion i
24 NA) is formed in the cell nucleus from viral relaxed circular DNA (rcDNA) by hijacking host DNA repai
25 s (HBV) contains a partially double-stranded relaxed circular DNA (rcDNA) genome that is converted in
26 on of replication-derived RNAs (rd-RNAs) and relaxed circular DNA (rcDNA) in serum provides more adeq
27 host DNA repair mechanisms to convert viral relaxed circular DNA (rcDNA) into a persistent viral gen
28 viously demonstrated that deproteinized (DP) relaxed circular DNA (rcDNA) of hepatitis B virus (HBV)
30 HBV cccDNA is converted from viral genomic relaxed circular DNA (rcDNA) through a complex process t
31 is formed by conversion of capsid-associated relaxed circular DNA (rcDNA) via unknown mechanisms and
32 end of the minus strand [(-)strand] of viral relaxed circular DNA (rcDNA), which generates a deprotei
34 loped experimental systems where various HBV relaxed-circular-DNA substrates are repaired to form ccc
35 ate for reverse transcription to produce the relaxed circular DNA that transforms into a covalently c
37 nctioning as loading sites for the enzyme as relaxed circular DNA treated with DNA gyrase, resulted i