1 renal function, persistent proteinuria, and
relentless accumulation of extracellular matrix leading
2 The
relentless adaptability of pathogen populations is a maj
3 Amyotrophic lateral sclerosis is a
relentless and devastating adult-onset neurodegenerative
4 However,
relentless and ever-deeper exploration and analysis of t
5 separated driver mutations, coupled with the
relentless and heterogeneous nature of the genome instab
6 nd health care professionals struggle with a
relentless and irreversible neurological syndrome that c
7 Clinical progression was
relentless and many children died in infancy.
8 ng in adulthood, tumor progression is rapid,
relentless,
and ultimately leads to the patient's death
9 To counteract this
relentless assault, cells have developed multiple pathwa
10 There is no better example of a
relentless attack on evidence-based biomedical research
11 In the
relentless battle against the COVID-19 pandemic, the dep
12 sts of public health importance due to their
relentless biting habits that can lead to allergies, sec
13 state of cellular amnesia, not only inducing
relentless cellular proliferation, but also bypassing ch
14 Plants are under
relentless challenge by pathogenic bacteria, fungi, and
15 tmentalized inflammation is thought to drive
relentless clinical deterioration.
16 This increase parallels the
relentless clinical progression seen in these disorders.
17 We suggest that this
relentless competition drives positive selection, promot
18 f these antibacterial molecules reflects the
relentless competition Streptomyces engage in with other
19 Throughout my career I was a
relentless consumer of the work of previous and current
20 Treatments that slow its
relentless course are not yet available, and biomarkers
21 utic approaches are available that alter the
relentless course of AD or other dementias of aging.
22 atric symptoms, weight loss, dementia, and a
relentless course with death about 20 years after diseas
23 Organisms are adapted to the
relentless cycles of day and night, because they evolved
24 lethal disease that is characterized by the
relentless death of motoneurons.
25 The
relentless decline in beta-cell function frequently obse
26 lation of fibroblasts and myofibroblasts and
relentless deposition of extracellular matrix (ECM).
27 cemia, consequent chronic hyperglycemia, and
relentless deterioration of beta-cell function.
28 Here, we show that rapid and
relentless dilution of surface water chemistry is occurr
29 The
relentless discovery of cancer biomarkers demands improv
30 The absence of effective treatments and
relentless disease course frequently leads to death in c
31 h T2DM is traditionally viewed as a chronic,
relentless disease in which delay of end-organ complicat
32 spread that may represent the mechanism for
relentless disease progression.
33 nderstanding of this molecule because of the
relentless efforts of multiple investigators who have di
34 To cope with
relentless environmental pressures, plants produce an ar
35 Chronic wasting disease (CWD) is a
relentless epidemic disorder caused by infectious prions
36 sometimes develop increasingly frequent and
relentless episodes of devastating generalized dystonia
37 ration of traits for attack and defense, but
relentless escalation of these arms races does not neces
38 Therapy to slow the
relentless expansion of interstitial extracellular matri
39 The
relentless expansion that threatens the sustainability o
40 e face of unyielding mortality rates and the
relentless expense of end-stage renal disease, governmen
41 osing panencephalitis (SSPE), a progressive,
relentless fatal disorder.
42 Amyotrophic lateral sclerosis (ALS) is a
relentless,
fatal neurodegenerative disease.
43 firm that inter-core XT distortions are more
relentless for cores fabricated around the central axis
44 by the AHA's new Mission Statement, to be a
relentless force for a world of longer, healthier lives,
45 of the American Heart Association is to be a
relentless force for a world of longer, healthier lives.
46 merican Heart Association's mission "to be a
relentless force for longer, healthier lives," this poli
47 ond century in its continued mission to be a
relentless force for longer, healthier lives.
48 from a well-characterized, early-onset, and
relentless form of photoreceptor cell degeneration.
49 As of this writing, the
relentless growth in computational power, the developmen
50 f radiologists in the United States has seen
relentless growth in recent years.
51 Trypanosoma brucei faces
relentless immune attack in the mammalian bloodstream, w
52 from all types of devices together with the
relentless increase in computer capacity is revolutioniz
53 Relentless increases in the size and performance of mult
54 The natural history of AMD demonstrates
relentless loss of vision in persons who developed advan
55 These cancers exhibit a
relentless malignant progression characterized by widesp
56 The
relentless march of a highly pathogenic avian influenza
57 The mechanism of
relentless muscle damage (a classic manifestation of the
58 The
relentless nature of treatment was also a burden, since
59 Amyotrophic lateral sclerosis (ALS) is a
relentless neurodegenerative disease of the human motor
60 considered in the differential diagnosis of
relentless otorrhea and external auditory canal stenosis
61 urophysiology have continued developing at a
relentless pace ever since.
62 steadily becoming glucose specialists by the
relentless pressure of mutation accumulation, which has
63 with complete remission in some patients and
relentless progression in others.
64 levated renal TGF-beta1 levels result in the
relentless progression of fibrotic disease.
65 e mutant, but not the wild-type, protein had
relentless progression of motor neuron loss with concomi
66 ses of the illness by preparing them for the
relentless progression of the disease and by supporting
67 -inflammatory therapies that may prevent the
relentless progression of the disease.
68 th the aim of identifying the causes of such
relentless progression through an insightful and critica
69 deprivation therapy experience relapse with
relentless progression to lethal metastatic castration-r
70 ve diseases are characterized by late onset,
relentless progression, and finally death.
71 rgo spontaneous regression while others show
relentless progression.
72 type, ranging from spontaneous regression to
relentless progression.
73 r genes usurp physiologic programs mandating
relentless proliferation and growth.
74 Relentless proliferation associated with self-sufficienc
75 y through the division cycle, leading to the
relentless proliferation characteristic of the neoplasti
76 Metastasis is the
relentless pursuit of cancer to escape its primary site
77 treatment, and monitoring owe much to Tom's
relentless pursuit of excellence in research and the tra
78 nts on the idea that natural selection is in
relentless pursuit of increasing organismal complexity,
79 The
relentless pursuit of miniaturization and performance en
80 se research activity on metallic glasses and
relentless pursuit of their structural description, the
81 In their
relentless pursuit of thinness, individuals with anorexi
82 Two-thirds had an insidious onset and a
relentless rather than stepwise progression of disabilit
83 ic neoplasm marked by local invasiveness and
relentless recurrence.
84 Relentless research efforts in molecular biology and dru
85 viduals with anorexia nervosa (AN) engage in
relentless restrictive eating and often become severely
86 most robust signals of climate change is the
relentless rise in global mean surface temperature, whic
87 Thus, the
relentless rise in global NH(3) emissions has positioned
88 D biosynthesis, it now may contribute to the
relentless rise in skin cancer incidence in humans.
89 ent relapse and remission, and those who had
relentless seizures.
90 Coevolutionary antagonism generates
relentless selection that can favour genetic exchange, i
91 Viruses are under
relentless selective pressure from host immune defenses.
92 r inability to prevent the frequently, often
relentless symptomatic recurrences of BV and to reduce s
93 he authors point out, they also counteract a
relentless tendency for positive emotions to become bori
94 Confounding by indication is a
relentless threat to validity in observational studies o