ライフサイエンスコーパス: remodel

1 flx embryos, the capillary network failed to remodel.

2 EA and ELIP genes, and evidence of cell wall remodeling.

3 o regulate brain entry through vascular wall remodeling.

4 ationship between insolubility and organelle remodeling.

5 MMP transport and its overall impact on ECM remodeling.

6 and PPARgamma levels, thus promoting airway remodeling.

7 chemic injury to reduce ongoing pathological remodeling.

8 omosome subdomains during meiotic chromosome remodeling.

9 aspect of microdamage accumulation and bone remodeling.

10 gy and immunohistochemistry to assess neural remodeling.

11 ke AF or AF+AFLs, does not induce structural remodeling.

12 erlying this beneficial electrophysiological remodeling.

13 s characterized by progressive fibrotic lung remodeling.

14 ferative gene programs during cardiovascular remodeling.

15 roles in extracellular matrix structure and remodeling.

16 helial-to-mesenchymal transition, and matrix remodeling.

17 d allowing for full quantification of tissue remodeling.

18 the endothelial cytoskeleton and junctional remodeling.

19 lar adhesion under tension during epithelial remodeling.

20 -fold lower cellular zinc concentration than remodeling.

21 in the mammary gland during postlactational remodeling.

22 th1 and the nucleosome acidic patch enhances remodeling.

23 e levels, possibly by regulating cardiolipin remodeling.

24 ) are enzymes involved in peptidoglycan (PG) remodeling.

25 n chromosome translocation and peptidoglycan remodeling.

26 ntributing to both electrical and structural remodeling.

27 link between T cell activation and chromatin remodeling.

28 chromatin-lamina interactions during nuclear remodeling.

29 coupling of bone formation to resorption in remodeling.

30 vely pushed along the gut as the matrix gets remodelled.

31 oration of fatigue resistance via angiogenic remodelling.

32 ization of IL-13 may reduce asthmatic airway remodelling.

33 vivo and their relation to regional myocyte remodelling.

34 est that FASN can mediate actin cytoskeletal remodelling; a process known to be downstream of Rho fam

35 PriA can recognize and remodel abandoned DNA replication forks, unwind DNA in t

36 tions in either causing attenuated chromatin remodeling activities.

37 ent transcript recruits repressive chromatin remodelling activities and the de novo methylation appar

38 gy and demonstrates that different chromatin remodelling activities are required for efficient repair

39 Recent work has shown that the remodeling acto-myosin network modifies local membrane o

40 ests that vascular EphA4-mediated neurogenic remodeling adversely affects learning and memory behavio

41 Adverse cardiac remodeling after myocardial infarction (MI) causes struc

42 eal the spatiotemporal evolution of vascular remodeling after stroke and demonstrate that a window of

43 Indicators of MU remodelling also progressively increased with age to a s

44 nscriptional program to induce ABCB1 through remodeling and activation of an ATF4-bound, stress-respo

45 (NGF), a neurotrophin associated with airway remodeling and airway hyperresponsiveness.

46 d 136 (14.2%) individuals with concentric LV remodeling and concentric LV hypertrophy, respectively.

47 revealed that Treg depletion blocked plaque remodeling and contraction, and impaired hallmarks of in

48 tein 2 (MTA2), a component of the nucleosome remodeling and deacetylase complex (NuRD).

49 es lead to a global pattern of cardiomyocyte remodeling and dedifferentiation, hallmarked by myolysis

50 Under stress, intensive chloroplast protein remodeling and degradation can occur, releasing large nu

51 diac cells and in the progression of cardiac remodeling and dysfunction.

52 behaviors underlying each stage of vascular remodeling and identify a pathway required for neointima

53 ent of collagen-related extracellular matrix remodeling and inflammatory activity in a murine model o

54 tologically observed, and modulated key bone remodeling and inflammatory mediators in rats with ligat

55 ization domain of angiopoietin-2 in vascular remodeling and lung metastasis and provides new insights

56 spontaneous autoimmune arthritis with joint remodeling and profound bone loss.

57 ignaling pathways before adverse ventricular remodeling and progression of HF.

58 ing and non-coding mutations, with chromatin remodeling and proliferation pathways altered primarily

59 tions in lung function, diminished pulmonary remodeling and regenerative capacity, and increased susc

60 ) mice, which exhibit defective cardiolipin remodeling and respiratory supercomplex instability char

61 encoding subunits of the SWI/SNF nucleosome-remodeling and SAGA chromatin-modifying complexes.

62 s demonstrate a mechanism of dystrophic Cx43 remodeling and suggest that targeting Cx43 may be a ther

63 -infarction significantly reduced adverse LV remodeling and the decline of cardiac function.

64 o define CF heterogeneity during ventricular remodeling and the underlying mechanisms that regulate C

65 In addition, they can modulate extracellular remodelling and intracellular pathways related to cell a

66 We propose a role for Gdf5 in tissue remodelling and repair after injury, which may partly un

67 However, how ATP powers substrate remodelling and whether a shared mechanism underlies the

68 rom ATP hydrolysis to physically reshape and remodel, and thus mature, the 60S subunit of the ribosom

69 e abnormalities, morphological and metabolic remodeling, and adverse clinical outcomes in patients wi

70 from transient forces while allowing spindle remodeling, and chromosome movements, over longer timesc

71 ry fibrotic lesions and extracellular matrix remodeling, and improved pulmonary function in bleomycin

72 restores OPOA by regulating subchondral bone remodeling, and may provide an effective method for repa

73 FD-induced cardiac dysfunction, pathological remodeling, and mitochondria dysfunction, as well.

74 s (SMCs), inflammation, extracellular matrix remodeling, and mitogens.

75 t, have salutary effects on left ventricular remodeling, and reduce hospitalization for HF and cardio

76 on through induction of angiogenesis, tissue remodeling, and suppression of the cytotoxic T lymphocyt

77 to examine the clinical profile, myocardial remodeling, and survival of patients with PPCM in Nigeri

78 nfluence of B cells on lung function, tissue remodeling, and the immune response were analyzed by usi

79 enes involved in asthma pathogenesis, tissue remodeling, and tight junction formation.

80 lial cells, mucus hypersecretion, and airway remodelling, and consequently might impact asthma sympto

81 d extracellular injury, pathological cardiac remodelling, and diastolic and systolic dysfunction.

82 prevent atherosclerosis progression, cardiac remodelling, and the resulting ischaemic heart disease a

83 ating gene expression, DNA repair, chromatin remodeling, apoptosis, and cell proliferation; but it re

84 ition, Nrf2KO inhibited cardiac pathological remodeling, apoptosis, and oxidative stress associated w

85 This nucleolar remodeling appears to be mediated through the class IIa

86 rovascular dysfunction, fibrosis, and tissue remodeling are needed and ideally would be obtained from

87 interact with fibroblasts and promote tissue remodelling are beginning to be understood and will be a

88 Other properties of post-MI remodelling are present in both peri-infarct and remote

89 lic dysfunction, particularly during cardiac remodeling, are not fully understood.

90 early genes (IEGs) and longer-term chromatin remodeling around secondary response genes (SRGs).

91 l arrival and disassembly, and suggest cargo remodeling as a novel function of dynein adaptors.

92 ted with reduced stiffness and higher tissue remodeling, as well as a dual mechanical behavior, sugge

93 AntimiR-21 effectively suppressed the remodeling-associated increase of miR-21.

94 Overall, we observe extensive remodeling at active enhancers in PAH PAECs and identify

95 sthma in mice with females developing airway remodelling at a much earlier stage than males.

96 eased cholesterol efflux capacity, favorably remodels atherosclerosis lesions, supporting the potenti

97 MARCB1, a conserved subunit of the chromatin remodeling BAF complex, which has known contributions to

98 of early diagnosis and treatment of cardiac remodeling because it may attenuate cancer progression a

99 k on specialized functions such as chromatin remodelling, biomarker potential and the recently discov

100 gulatory sites by two eIF2(alphaP) molecules remodels both the ISRIB-binding pocket and the pockets t

101 cardiovascular disease due to its ability to remodel cardiac tissue and generate angiotensin II.

102 ng [>=12% decrease in LVESV]; group 2: no LV remodeling [changes in LVEDV and LVESV <12%]; group 3: a

103 st-translationally modifying histones and/or remodeling chromatin structure.

104 non-fermentable (mSWI/SNF or BAF) chromatin remodeling complex, including its core catalytic subunit

105 s, including HMGB1 and the SWI/SNF chromatin remodeling complex, that are SARS lineage and pan-corona

106 y exclusive ATPases of the SWI/SNF chromatin remodeling complex.

107 able other transcription factors, nucleosome remodeling complexes, and histone modifiers to engage ch

108 t BAF60a, a subunit of the SWI/SNF chromatin-remodeling complexes, serves an indispensable role in co

109 sferases and the SWI/SNF family of chromatin remodelling complexes - regulate gene expression and dev

110 h constituents of the NURD and BAF chromatin remodelling complexes.

111 ng the infarct, but whether and how vascular remodeling contributes to recovery are unclear.

112 DENV reconfigures phospholipids through the remodeling cycle to modify the endomembrane and facilita

113 6 causes ciliary abnormalities, ductal plate remodeling defects and periportal fibrosis in the liver.

114 tionally showed activation-related metabolic remodeling deficits and decreased mitochondrial membrane

115 rimary endpoint was a recurrence of negative remodeling, defined as an increase in left ventricular e

116 Biochemical assays and structural remodeling demonstrate that the base pairings in the ste

117 Interestingly, this metabolic remodeling did not improve insulin resistance, but induc

118 The scleral remodeling due to mass effect of retrobulbar tumor also

119 erlying molecular pathways that drive atrial remodeling during cardiac pressure overload are poorly d

120 Nucleoid remodeling during cell growth and environmental adaptati

121 hoGEF-anillin module in septin architectural remodeling during cytokinesis at the filament level.

122 We hypothesized that epithelial remodeling during diseases characterized by cilial loss

123 markers, Symptom Improvement and Ventricular Remodeling During Entresto Therapy for Heart Failure).

124 We demonstrated the early induction of remodeling during infection by using isotope tracing in

125 ch has been reported about their function in remodeling ECM in health and disease, their trafficking

126 y end point), quality of life, LV structural remodeling ( EF >5% and ESV 10%) and heart failure event

127 he short- (bone healing) and long-term (bone remodeling) effects of initial implant micromotion durin

128 ATP-dependent chromatin-remodeling enzymes control accessibility, nucleosome pos

129 ATP-dependent chromatin remodelling enzymes facilitate different DNA repair path

130 Altered PAR-2 polarization in disease-remodeled epithelia may enhance apical responses and inc

131 spective DNA binding or downstream chromatin-remodeling events have shown promise in preclinical stud

132 transport (ESCRTs) mediate diverse membrane remodeling events.

133 This basement membrane remodelling facilitates embryo growth before gastrulatio

134 eal the mechanism underlying how a chromatin remodeling factor can regulate oocyte meiosis.

135 e and shows how a highly conserved chromatin remodeling factor has a distinct role in anti-microbial

136 ferase 1 (CARM1) methylates Pontin chromatin-remodeling factor under glucose starvation, and methylat

137 Smarcad1 is a conserved chromatin remodeling factor with a poorly understood tissue functi

138 Mutations in specific chromatin-remodeling factors appear to be key determinants of the

139 Jag1 mutants until later stages, when ductal remodeling fails, and signs of acinar-to-ductal metaplas

140 show that Dysf(-/-) mice develop adverse LV remodeling following I/R injury secondary to the collate

141 nuated inflammation and abrogated adverse LV remodeling following I/R injury.

142 ed mutations in genes involved in chromosome remodelling (for example, PBRM1, BAP1 and SETD2), DNA me

143 The impact on RV remodeling, functional status, and quality of life over

144 To study 1-year changes in RV remodeling, functional status, and quality of life, we a

145 roteins with known mycomembrane synthesis or remodeling functions (CmrA, MmpL3, Ag85, Tdmh), and nume

146 /Amphiphysin/Rvs (BAR) domain, have membrane-remodeling functions, particularly at the endosome.

147 Motivated by the dynamic expression in remodeling gamma-neurons, we focus here on the role of a

148 aride and capsule synthesis genes, cell wall remodeling genes (lytN, ddh), the urease operon, genes i

149 ram modulates the expression of key neuronal remodeling genes, including S100a10 (p11), linking neuro

150 of the following groups (group 1: reverse LV remodeling [>=12% decrease in LVESV]; group 2: no LV rem

151 ease in LVEDV only]; and group 4: adverse LV remodeling [>=12% increase in both LVESV and LVEDV]) was

152 Global translational remodeling has emerged as a principal mechanism of biolo

153 cal score (RAISE) that used left ventricular remodeling (hypertrophy/diastolic dysfunction), age, inj

154 ansmembrane Lem2-Nur1 complex at the INM are remodeled in interphase by the ESCRT-III/Vps4 machinery.

155 pacity and promotes left ventricular reverse remodeling in asymptomatic or minimally symptomatic pati

156 filtration of activated PECs may disrupt ECM remodeling in cFSGS.

157 mics signature revealed abnormal cardiolipin remodeling in diabetic kidneys, a cardinal sign of disru

158 nce a mechanistic understanding of chromatin remodeling in disease states.

159 Our work reveals a key role for TAD remodeling in epigenetic regulation of transcription and

160 mineral density (BMD) and biomarkers of bone remodeling in HIV/HCV coinfected patients.

161 rse of the development of pulmonary vascular remodeling in PAH rats.

162 Neural remodeling in PVC-CM is characterized by extracardiac sy

163 This demonstrates the important role of ECC remodeling in the cardiac dysfunction secondary to chron

164 degeneration suggests moderate, stereotyped remodeling in the early stages of the human disease and

165 oligodendrocyte generation and myelin sheath remodeling in the forelimb motor cortex.

166 nesis, but also the perpetuation of electric remodeling in the intact, fibrillating atrium.

167 activity limits microglia-mediated neuronal remodeling in the medial PFC, and subsequent behavioral

168 alamic system undergoes significant synaptic remodeling in the parkinsonian state.

169 l disease characterized by profound vascular remodeling in which pulmonary arteries narrow because of

170 role of transcription factors and epigenetic remodelling in macrophages in the context of atheroscler

171 monstrated that HF-induced atrial electrical remodelling increased susceptibility to atrial alternans

172 of PP2A signaling prevents eccentric cardiac remodeling induced by myocardial infarction, in each cas

173 f RSK3 signaling prevents concentric cardiac remodeling induced by pressure overload, while inhibitio

174 The hourglass is remodeled into a double ring that sandwiches the actomyo

175 This remodeling involves disassembly of old microtubules and

176 Epithelial remodeling involves ratcheting behavior whereby periodic

177 Extracellular matrix (ECM) remodeling is a hallmark of the pathology of gastrointes

178 Developmental synaptic remodeling is important for the formation of precise neu

179 Pial collateral remodeling is limited by the crosstalk between EphA4-Tie

180 In eukaryotic cells, proteome remodeling is mediated by the ubiquitin-proteasome syste

181 To study how normal developmental remodeling is mediated, we used fluorescently tagged act

182 s into NE holes together with ESCRT-mediated remodeling is required for nuclear closure.

183 Given that adverse remodeling is the leading cause of heart failure and dea

184 effect of boron on cardiac contractility and remodeling is unknown.

185 ether, our results suggest that 3D epigenome remodelling is a key mechanism underlying endocrine resi

186 splicing or ribosome biogenesis, where they remodel large RNA-protein complexes to facilitate transi

187 depletion, translation of specific mRNAs was remodeled leading to reduced production of collagens, lo

188 g factors and consequent pre-mRNA structural remodeling, leading up to assembly of the early spliceos

189 and enCRISPRi modulate gene transcription by remodeling local epigenetic landscapes at sgRNA-targeted

190 n the association between sex and LV reverse remodeling (LV end-systolic volume change) and sex and t

191 We show that the remodelled lymphatic vessel displayed increasing intrins

192 y sheds light onto the role of the chromatin remodeling machinery in intestinal epithelial cells in t

193 The chromatin-remodeling machinery that governs genome accessibility a

194 bserved for other AAA+ proteases and protein-remodeling machines.

195 be reduced secondary to high pressures, but remodelling may increase perfusion heterogeneity.

196 erizes microdamage accumulation and abnormal remodeling mechanisms in the diabetic skeleton, which ad

197 tracellular matrix via specialized molecular remodeling mechanisms that are independent of the bone f

198 failure rate resulting from excessive inward remodeling, medial fibrosis, and thrombosis.

199 ial transcriptional factor of cardiovascular remodeling, mediates the link between mitochondrial dyna

200 y driving angiogenesis, extracellular matrix remodelling, metastasis and immunosuppression.

201 both in culture and in vivo by lipidome-wide remodeling, most notably upregulation of saturated lipid

202 odulated by the ATP-driven SWI/SNF chromatin remodeling multiprotein complexes BAF (BRG1/BRM-associat

203 variability) and biomarkers of peripheral MU remodelling (MUP size, complexity, stability).

204 hich prevents the basal extracellular matrix remodelling necessary for wing morphogenesis.

205 ded biologics that can efficiently repair or remodel neuronal circuits.

206 XBP-1s therefore remodels neuronal signaling to coordinately modulate int

207 ent forces acting on the nuclear envelope to remodel nuclear shape, which might be a defining feature

208 hromatin remodelers that directly engage and remodel nucleosomes or transcription elongation factors

209 echanosignaling loop involving the autocrine remodeling of a drug-protective ECM.

210 are crucial in dictating the deformation and remodeling of a thrombus after its formation in hemostas

211 entify Sox17 as a critical regulator for the remodeling of coronary vessels in the developing heart.

212 Time course analysis revealed rapid remodeling of diverse host systems, including signaling,

213 of SHF-derived ECs to pharyngeal arches, the remodeling of endothelial plexus into the PAAs, and the

214 1) are neurotropic, and (2) cause structural remodeling of hippocampal dendrites.

215 Enterovirus infection induces the massive remodeling of intracellular membranes and the developmen

216 Further topological remodeling of light and dark zone follicular dendritic c

217 High glucose-induced remodeling of microtubule network facilitates robust GSI

218 godendrocytes can regulate the formation and remodeling of myelin sheaths and perhaps additional func

219 ting depression-like behaviors via dendritic remodeling of NAc D1-MSNs and may prove a useful target

220 ng a critical function in loads transfer and remodeling of the alveolar bone.

221 ondrial antiviral signaling (MAVS)-dependent remodeling of the cell surface, increasing surface prese

222 or microenvironment, leading to an extensive remodeling of the ECM and an increased infiltration of C

223 cell proliferation, migration, adhesion, and remodeling of the extracellular matrix.

224 Biosynthesis and remodeling of the GPI anchor requires the activity of ov

225 n genome-wide recombination rate rather than remodeling of the local recombination landscape.

226 of endothelial plexus into the PAAs, and the remodeling of the PAAs into the aortic arch artery and i

227 Chronic hypoxia leads to pathologic remodeling of the pulmonary vasculature and pulmonary hy

228 Each stress induced rapid remodeling of the RNA-protein interactome without corres

229 might underlie distinctions in pathological remodeling of the RV in biventricular HF.

230 regeneration requires precisely coordinated remodeling of the transcriptional landscape to enable th

231 subsequently promotes tumor progression and remodeling of the tumor microenvironment (TME) by sustai

232 at distinct classes of neurons individualize remodeling of their myelination profiles to diversify ci

233 ranscriptomic analysis, revealing a striking remodeling of transcripts involved in neuronal signaling

234 Stroke causes remodeling of vasculature surrounding the infarct, but w

235 ntain osmotic and protein homeostasis during remodelling of eukaryotic proteomes, and that bioenerget

236 for the excessive synthesis, deposition and remodelling of extracellular matrix proteins in fibrosis

237 pithelial repair responses may contribute to remodelling of the airway wall.

238 epidermis, meanwhile, softening and enhanced remodelling of the basement membrane promote tumour budd

239 rogression as a result of tissue healing and remodelling of the blood vasculature, causing cancer cel

240 e of aneurysm plays an important role in the remodelling of the carotid arteries.

241 abolic pathways linked to the early and late remodelling of the left and right ventricle over the cou

242 undergo a dramatic, complex and coordinated remodelling of their cytoskeleton and membranes.

243 al characteristics, left ventricular reverse remodeling, or outcomes on multivariable analysis (P=0.0

244 athophysiology leading to Fontan palliation, remodelling, or increased gravitational gradients from l

245 h composition and interactions to manage and remodel partially-unwrapped nucleosomes.

246 7 and BRD9, which form part of the chromatin remodeling PBAF and BAF complexes, respectively.

247 uctural analysis showed that Phactr1 binding remodels PP1's hydrophobic groove, creating a new compos

248 ts were regulated by T cells during the bone remodeling process.

249 ntains multipotent cells is involved in this remodeling process.

250 how replication forks are actively stalled, remodelled, processed, protected and restarted in respon

251 the mechanisms of diverse cellular membrane remodeling processes.

252 r, the variants impair DAAM2-dependent actin remodeling processes: wild-type DAAM2 cDNA, but not cDNA

253 nistically, ZNF367 interacted with chromatin remodeling protein BRG1 and transcriptionally activated

254 lthough LSH belongs to a family of chromatin remodeling proteins, it remains unknown how LSH mediates

255 mains for multiple steps of the nucleic acid remodeling reactions.

256 olytic metabolism, collagen biosynthesis and remodeling, redox regulation and immunomodulatory protei

257 t microRNAs (miR-24-4, miR-21), cytoskeleton remodeling, response to stimuli, and inflammation can im

258 blication, we also clarify that the junction-remodelling role of Mpp5a is not specific to dividing ce

259 creased cell-cell coupling due to structural remodelling slow electrical propagation and provide obst

260 , and CCL26 and genes associated with tissue remodeling, such as COL8A1, actin gamma-2 (ACTG2), and t

261 ith RNase P undergo an unexpected RNA-driven remodeling that allows them to bind to divergent RNAs.

262 Taken together, 17-AAG liposomes could remodel the immunosuppressive microenvironment of triple

263 e mechanisms that underlie how these tumours remodel the neuronal milieu towards increased activity a

264 h acts to drive progressive cell commitment, remodeling the epigenomic landscape to define the presum

265 hat STAT5 is the earliest factor binding and remodeling the Il9 locus to allow BATF binding in both m

266 whereby AML impairs normal hematopoiesis by remodeling the mesenchymal niche.

267 proteins required for growing, repairing or remodelling the nacreous shell layer, whereas the second

268 omotes the dynamic assembly of microtubules, remodels the cytoskeleton, and enhances the acetylation

269 g "tandem duplication," a cell division that remodels the parental cell into two daughter cells.

270 hMSCs can regulate arrhythmia substrates by remodeling their secretome in disease.

271 mitochondrial homeostasis, including cristae remodeling; therefore, we examined the photoreceptors of

272 ic rearrangements, contributing to oncogenic remodeling through chimeric circularization and reintegr

273 ting the rapid evolution of regions that are remodelled through ontogeny.

274 osin II filaments and a global change from a remodeling to a contractile state of the acto-myosin net

275 ge, improves cardiac function, and mitigates remodeling to a larger extent than when administered ora

276 amic array of filaments that undergoes rapid remodeling to drive many cellular processes.

277 cellular signaling cascades and cytoskeletal remodeling to support optimal inclusion development and

278 Tumours leverage ECM remodelling to create a microenvironment that promotes t

279 d that statin-mediated cholesterol depletion remodels total vascular smooth muscle cell cytoskeletal

280 gous and homozygous regions causes crossover remodelling towards the heterozygous regions in wild typ

281 ult of a complex interplay between chromatin remodeling, transcription factors, and signaling molecul

282 stem cell (LSC) retention and growth in the remodeled tumor-promoting BM is unclear.

283 the ANGPT2 N-terminal domain in blood vessel remodeling, tumor growth, metastasis, integrin binding,

284 ivity occur due to electrical and structural remodelling under Pitx2 deficiency conditions.

285 fined, albeit flexible 3-D structure that is remodeled upon CNBP binding.

286 nisation of these clusters, and how they are remodelled upon developmental transitions remain poorly

287 uscle cells resulted in viable offspring and remodeled vasculature and did not recapitulate the betaA

288 eases in the flow-generation capacity of the remodelled vessel at the expense of normal mitochondrial

289 genesis and formed a hierarchical network of remodeled vessels, whereas in betaA-Akt1WT/flx embryos,

290 gonism can attenuate aortic inflammation and remodeling via decreased smooth muscle cell activation a

291 ing cardiomyopathy, and cardiac function and remodeling was assessed by echocardiography 10 weeks aft

292 Previously, SWI/SNF chromatin remodeling was found to define the kinetics and selectiv

293 The only predictor of left ventricular remodeling was treatment with sonothrombolysis: the cont

294 was more likely to exhibit left ventricular remodeling with an odds ratio of 2.79 ([95% CI, 0.13-6.8

295 n LVEDV and LVESV <12%]; group 3: adverse LV remodeling with compensation [>=12% increase in LVEDV on

296 ndamental to the study of heart function and remodeling with health and disease.

297 impaired relaxation and evoked hypertrophic remodeling with increased energetic stress.

298 but not mdxS3A, mice were resistant to Cx43 remodeling, with a corresponding reduction of Cx43 hemic

299 ogressive disease leads to pathologic tissue remodeling, with ensuing esophageal rigidity and loss of

300 tions cardiac lymphatics undergo significant remodeling, with insufficient lymphatic function and/or