ライフサイエンスコーパス: remodeling

1 MMP transport and its overall impact on ECM remodeling.

2 and PPARgamma levels, thus promoting airway remodeling.

3 omosome subdomains during meiotic chromosome remodeling.

4 aspect of microdamage accumulation and bone remodeling.

5 gy and immunohistochemistry to assess neural remodeling.

6 ke AF or AF+AFLs, does not induce structural remodeling.

7 chemic injury to reduce ongoing pathological remodeling.

8 erlying this beneficial electrophysiological remodeling.

9 s characterized by progressive fibrotic lung remodeling.

10 ferative gene programs during cardiovascular remodeling.

11 roles in extracellular matrix structure and remodeling.

12 d allowing for full quantification of tissue remodeling.

13 the endothelial cytoskeleton and junctional remodeling.

14 lar adhesion under tension during epithelial remodeling.

15 helial-to-mesenchymal transition, and matrix remodeling.

16 -fold lower cellular zinc concentration than remodeling.

17 th1 and the nucleosome acidic patch enhances remodeling.

18 e levels, possibly by regulating cardiolipin remodeling.

19 ) are enzymes involved in peptidoglycan (PG) remodeling.

20 ar processes including division and membrane remodeling.

21 in the mammary gland during postlactational remodeling.

22 occur in part through collagen synthesis or remodeling.

23 veolar bone loss following extraction socket remodeling.

24 sm driving neural circuit deconstruction and remodeling.

25 laments towards the membrane during membrane remodeling.

26 w of rapid behavioral development and neural remodeling.

27 mation, leukocyte infiltration, and vascular remodeling.

28 n chromosome translocation and peptidoglycan remodeling.

29 ctility and reduction in adverse ventricular remodeling.

30 during the healing phase but resorbed during remodeling.

31 y, v) fibrosis, and vi) cardiac function and remodeling.

32 ntributing to both electrical and structural remodeling.

33 ith molecular-level tracking of cytoskeletal remodeling.

34 VSD had evidence of left ventricular reverse remodeling.

35 activation and deficits in structural spine remodeling.

36 link between T cell activation and chromatin remodeling.

37 chromatin-lamina interactions during nuclear remodeling.

38 coupling of bone formation to resorption in remodeling.

39 EA and ELIP genes, and evidence of cell wall remodeling.

40 o regulate brain entry through vascular wall remodeling.

41 ationship between insolubility and organelle remodeling.

42 tions in either causing attenuated chromatin remodeling activities.

43 Recent work has shown that the remodeling acto-myosin network modifies local membrane o

44 ests that vascular EphA4-mediated neurogenic remodeling adversely affects learning and memory behavio

45 Adverse cardiac remodeling after myocardial infarction (MI) causes struc

46 eal the spatiotemporal evolution of vascular remodeling after stroke and demonstrate that a window of

47 lular functions, and they regulate chromatin remodeling, along with transcriptional and post-transcri

48 vidual pacemaker cells along with structural remodeling and a blunted beta-adrenergic response.

49 results indicate robust intratumoral immune remodeling and a window of tumor-resident T cell expansi

50 nscriptional program to induce ABCB1 through remodeling and activation of an ATF4-bound, stress-respo

51 (NGF), a neurotrophin associated with airway remodeling and airway hyperresponsiveness.

52 vides potential targets to modulate vascular remodeling and calcification in the context of mineral i

53 d 136 (14.2%) individuals with concentric LV remodeling and concentric LV hypertrophy, respectively.

54 revealed that Treg depletion blocked plaque remodeling and contraction, and impaired hallmarks of in

55 tein 2 (MTA2), a component of the nucleosome remodeling and deacetylase complex (NuRD).

56 es lead to a global pattern of cardiomyocyte remodeling and dedifferentiation, hallmarked by myolysis

57 Under stress, intensive chloroplast protein remodeling and degradation can occur, releasing large nu

58 diac cells and in the progression of cardiac remodeling and dysfunction.

59 scar thinning ratio, expansion, and cardiac remodeling and function were severely affected from the

60 dforward circuit is essential for intestinal remodeling and helminth clearance.

61 sented by these proteins may mediate cardiac remodeling and HF risk and to assess if these proteins c

62 behaviors underlying each stage of vascular remodeling and identify a pathway required for neointima

63 e Mcub gene exacerbated pathological cardiac remodeling and infarct expansion after ischemic injury i

64 ent of collagen-related extracellular matrix remodeling and inflammatory activity in a murine model o

65 tologically observed, and modulated key bone remodeling and inflammatory mediators in rats with ligat

66 ization domain of angiopoietin-2 in vascular remodeling and lung metastasis and provides new insights

67 spontaneous autoimmune arthritis with joint remodeling and profound bone loss.

68 ignaling pathways before adverse ventricular remodeling and progression of HF.

69 ing and non-coding mutations, with chromatin remodeling and proliferation pathways altered primarily

70 roves left ventricular systolic function and remodeling and reduces natriuretic peptides.

71 tions in lung function, diminished pulmonary remodeling and regenerative capacity, and increased susc

72 ) mice, which exhibit defective cardiolipin remodeling and respiratory supercomplex instability char

73 encoding subunits of the SWI/SNF nucleosome-remodeling and SAGA chromatin-modifying complexes.

74 on in the spinal dorsal horn prevented spine remodeling and significantly reduced inflammatory and ne

75 s demonstrate a mechanism of dystrophic Cx43 remodeling and suggest that targeting Cx43 may be a ther

76 -infarction significantly reduced adverse LV remodeling and the decline of cardiac function.

77 o define CF heterogeneity during ventricular remodeling and the underlying mechanisms that regulate C

78 e abnormalities, morphological and metabolic remodeling, and adverse clinical outcomes in patients wi

79 from transient forces while allowing spindle remodeling, and chromosome movements, over longer timesc

80 B-type natriuretic peptide), cardiac reverse remodeling, and health status scores were compared betwe

81 ate immune responses trigger changes in bone remodeling, and how model systems can be leveraged to id

82 ry fibrotic lesions and extracellular matrix remodeling, and improved pulmonary function in bleomycin

83 restores OPOA by regulating subchondral bone remodeling, and may provide an effective method for repa

84 FD-induced cardiac dysfunction, pathological remodeling, and mitochondria dysfunction, as well.

85 s (SMCs), inflammation, extracellular matrix remodeling, and mitogens.

86 methylation, histone modification, chromatin remodeling, and noncoding RNA expression, and elucidates

87 t, have salutary effects on left ventricular remodeling, and reduce hospitalization for HF and cardio

88 on through induction of angiogenesis, tissue remodeling, and suppression of the cytotoxic T lymphocyt

89 to examine the clinical profile, myocardial remodeling, and survival of patients with PPCM in Nigeri

90 nfluence of B cells on lung function, tissue remodeling, and the immune response were analyzed by usi

91 enes involved in asthma pathogenesis, tissue remodeling, and tight junction formation.

92 lar stiffness and regulation of cytoskeletal remodeling; and (d) TRPV4-Rac1 signaling axis is critica

93 ating gene expression, DNA repair, chromatin remodeling, apoptosis, and cell proliferation; but it re

94 ition, Nrf2KO inhibited cardiac pathological remodeling, apoptosis, and oxidative stress associated w

95 This nucleolar remodeling appears to be mediated through the class IIa

96 rovascular dysfunction, fibrosis, and tissue remodeling are needed and ideally would be obtained from

97 lic dysfunction, particularly during cardiac remodeling, are not fully understood.

98 early genes (IEGs) and longer-term chromatin remodeling around secondary response genes (SRGs).

99 l arrival and disassembly, and suggest cargo remodeling as a novel function of dynein adaptors.

100 ted with reduced stiffness and higher tissue remodeling, as well as a dual mechanical behavior, sugge

101 AntimiR-21 effectively suppressed the remodeling-associated increase of miR-21.

102 Overall, we observe extensive remodeling at active enhancers in PAH PAECs and identify

103 MARCB1, a conserved subunit of the chromatin remodeling BAF complex, which has known contributions to

104 of early diagnosis and treatment of cardiac remodeling because it may attenuate cancer progression a

105 Genital cell remodeling by HIV includes downregulating TCR complex co

106 nt; however, if unregulated, abnormal muscle remodeling can occur, such as in the heart following car

107 ng [>=12% decrease in LVESV]; group 2: no LV remodeling [changes in LVEDV and LVESV <12%]; group 3: a

108 st-translationally modifying histones and/or remodeling chromatin structure.

109 non-fermentable (mSWI/SNF or BAF) chromatin remodeling complex, including its core catalytic subunit

110 s, including HMGB1 and the SWI/SNF chromatin remodeling complex, that are SARS lineage and pan-corona

111 y exclusive ATPases of the SWI/SNF chromatin remodeling complex.

112 able other transcription factors, nucleosome remodeling complexes, and histone modifiers to engage ch

113 t BAF60a, a subunit of the SWI/SNF chromatin-remodeling complexes, serves an indispensable role in co

114 ng the infarct, but whether and how vascular remodeling contributes to recovery are unclear.

115 DENV reconfigures phospholipids through the remodeling cycle to modify the endomembrane and facilita

116 6 causes ciliary abnormalities, ductal plate remodeling defects and periportal fibrosis in the liver.

117 tionally showed activation-related metabolic remodeling deficits and decreased mitochondrial membrane

118 rimary endpoint was a recurrence of negative remodeling, defined as an increase in left ventricular e

119 Biochemical assays and structural remodeling demonstrate that the base pairings in the ste

120 Interestingly, this metabolic remodeling did not improve insulin resistance, but induc

121 The scleral remodeling due to mass effect of retrobulbar tumor also

122 e maturation was necessary to undergo vessel remodeling during angiogenesis.

123 erlying molecular pathways that drive atrial remodeling during cardiac pressure overload are poorly d

124 Nucleoid remodeling during cell growth and environmental adaptati

125 hoGEF-anillin module in septin architectural remodeling during cytokinesis at the filament level.

126 We hypothesized that epithelial remodeling during diseases characterized by cilial loss

127 While the ECM can undergo acute remodeling during embryogenesis, it is experimentally di

128 markers, Symptom Improvement and Ventricular Remodeling During Entresto Therapy for Heart Failure).

129 We demonstrated the early induction of remodeling during infection by using isotope tracing in

130 ch has been reported about their function in remodeling ECM in health and disease, their trafficking

131 y end point), quality of life, LV structural remodeling ( EF >5% and ESV 10%) and heart failure event

132 he short- (bone healing) and long-term (bone remodeling) effects of initial implant micromotion durin

133 t that conditional knockout of the chromatin remodeling enzyme Chd4 in granule neurons of the mouse c

134 is perturbed because of mutations in the CL-remodeling enzyme, tafazzin.

135 ATP-dependent chromatin-remodeling enzymes control accessibility, nucleosome pos

136 ontractile SMC markers, extracellular matrix remodeling enzymes, and cytokines/receptors.

137 spective DNA binding or downstream chromatin-remodeling events have shown promise in preclinical stud

138 transport (ESCRTs) mediate diverse membrane remodeling events.

139 Treg-specific deletion of the chromatin remodeling factor Brg1 impairs Treg cell activation and

140 eal the mechanism underlying how a chromatin remodeling factor can regulate oocyte meiosis.

141 e and shows how a highly conserved chromatin remodeling factor has a distinct role in anti-microbial

142 ferase 1 (CARM1) methylates Pontin chromatin-remodeling factor under glucose starvation, and methylat

143 Smarcad1 is a conserved chromatin remodeling factor with a poorly understood tissue functi

144 Mutations in specific chromatin-remodeling factors appear to be key determinants of the

145 Jag1 mutants until later stages, when ductal remodeling fails, and signs of acinar-to-ductal metaplas

146 show that Dysf(-/-) mice develop adverse LV remodeling following I/R injury secondary to the collate

147 nuated inflammation and abrogated adverse LV remodeling following I/R injury.

148 The impact on RV remodeling, functional status, and quality of life over

149 To study 1-year changes in RV remodeling, functional status, and quality of life, we a

150 roteins with known mycomembrane synthesis or remodeling functions (CmrA, MmpL3, Ag85, Tdmh), and nume

151 /Amphiphysin/Rvs (BAR) domain, have membrane-remodeling functions, particularly at the endosome.

152 Motivated by the dynamic expression in remodeling gamma-neurons, we focus here on the role of a

153 aride and capsule synthesis genes, cell wall remodeling genes (lytN, ddh), the urease operon, genes i

154 ram modulates the expression of key neuronal remodeling genes, including S100a10 (p11), linking neuro

155 of the following groups (group 1: reverse LV remodeling [>=12% decrease in LVESV]; group 2: no LV rem

156 ease in LVEDV only]; and group 4: adverse LV remodeling [>=12% increase in both LVESV and LVEDV]) was

157 Global translational remodeling has emerged as a principal mechanism of biolo

158 cal score (RAISE) that used left ventricular remodeling (hypertrophy/diastolic dysfunction), age, inj

159 nt a novel approach to characterize vascular remodeling in adult mice using Adipo-Clear in combinatio

160 dative injury likely contributes to electric remodeling in AF by upregulating I(KACh) by a mechanism

161 s the onset, and the maintenance of electric remodeling in AF, as well, and (2) can be successfully p

162 pacity and promotes left ventricular reverse remodeling in asymptomatic or minimally symptomatic pati

163 filtration of activated PECs may disrupt ECM remodeling in cFSGS.

164 mics signature revealed abnormal cardiolipin remodeling in diabetic kidneys, a cardinal sign of disru

165 nce a mechanistic understanding of chromatin remodeling in disease states.

166 Our work reveals a key role for TAD remodeling in epigenetic regulation of transcription and

167 mineral density (BMD) and biomarkers of bone remodeling in HIV/HCV coinfected patients.

168 rse of the development of pulmonary vascular remodeling in PAH rats.

169 The presence and significance of neural remodeling in premature ventricular contraction-induced

170 Neural remodeling in PVC-CM is characterized by extracardiac sy

171 rdiomyocytes attenuates pathological cardiac remodeling in response to pressure overload.

172 Actin cytoskeleton remodeling in spines is a key element of their formation

173 This demonstrates the important role of ECC remodeling in the cardiac dysfunction secondary to chron

174 sical processes such as extracellular matrix remodeling in the case of mesenchymal spheroids and diff

175 at mechanosensor YAP as a key player in ECM remodeling in the diseased heart via transcriptional act

176 degeneration suggests moderate, stereotyped remodeling in the early stages of the human disease and

177 oligodendrocyte generation and myelin sheath remodeling in the forelimb motor cortex.

178 nesis, but also the perpetuation of electric remodeling in the intact, fibrillating atrium.

179 stem is inextricably linked to wound healing/remodeling in the ischemically injured heart, the repara

180 rt failure induces electrical and structural remodeling in the left atrium (LA) that begets atrial my

181 activity limits microglia-mediated neuronal remodeling in the medial PFC, and subsequent behavioral

182 F1 signaling and microglia-mediated neuronal remodeling in the medial PFC.

183 alamic system undergoes significant synaptic remodeling in the parkinsonian state.

184 DNA translocation efficiency and nucleosome remodeling in vitro.

185 l disease characterized by profound vascular remodeling in which pulmonary arteries narrow because of

186 of PP2A signaling prevents eccentric cardiac remodeling induced by myocardial infarction, in each cas

187 f RSK3 signaling prevents concentric cardiac remodeling induced by pressure overload, while inhibitio

188 This remodeling involves disassembly of old microtubules and

189 Epithelial remodeling involves ratcheting behavior whereby periodic

190 Extracellular matrix (ECM) remodeling is a hallmark of the pathology of gastrointes

191 Immune evasion through membrane remodeling is a hallmark of Yersinia pestis pathogenesis

192 Because matrix remodeling is critical to the formation and growth of th

193 Developmental synaptic remodeling is important for the formation of precise neu

194 Pial collateral remodeling is limited by the crosstalk between EphA4-Tie

195 In eukaryotic cells, proteome remodeling is mediated by the ubiquitin-proteasome syste

196 To study how normal developmental remodeling is mediated, we used fluorescently tagged act

197 s into NE holes together with ESCRT-mediated remodeling is required for nuclear closure.

198 Given that adverse remodeling is the leading cause of heart failure and dea

199 effect of boron on cardiac contractility and remodeling is unknown.

200 g factors and consequent pre-mRNA structural remodeling, leading up to assembly of the early spliceos

201 and enCRISPRi modulate gene transcription by remodeling local epigenetic landscapes at sgRNA-targeted

202 n the association between sex and LV reverse remodeling (LV end-systolic volume change) and sex and t

203 y sheds light onto the role of the chromatin remodeling machinery in intestinal epithelial cells in t

204 The chromatin-remodeling machinery that governs genome accessibility a

205 bserved for other AAA+ proteases and protein-remodeling machines.

206 erizes microdamage accumulation and abnormal remodeling mechanisms in the diabetic skeleton, which ad

207 diabetic skeleton and the corresponding bone remodeling mechanisms remain poorly understood.

208 tracellular matrix via specialized molecular remodeling mechanisms that are independent of the bone f

209 failure rate resulting from excessive inward remodeling, medial fibrosis, and thrombosis.

210 ial transcriptional factor of cardiovascular remodeling, mediates the link between mitochondrial dyna

211 both in culture and in vivo by lipidome-wide remodeling, most notably upregulation of saturated lipid

212 odulated by the ATP-driven SWI/SNF chromatin remodeling multiprotein complexes BAF (BRG1/BRM-associat

213 echanosignaling loop involving the autocrine remodeling of a drug-protective ECM.

214 are crucial in dictating the deformation and remodeling of a thrombus after its formation in hemostas

215 ion imaging reveals that confinement induces remodeling of actomyosin stress fiber architecture.

216 Bone homeostasis requires continuous remodeling of bone matrix to maintain structural integri

217 entify Sox17 as a critical regulator for the remodeling of coronary vessels in the developing heart.

218 l deletion of Sox17 causes deficient cardiac remodeling of coronary vessels, resulting in improper co

219 ical TF upregulated during the sprouting and remodeling of coronary vessels, visualized by a specific

220 Time course analysis revealed rapid remodeling of diverse host systems, including signaling,

221 f ATAC-Seq profiling demonstrated a dramatic remodeling of DNA accessibility in the PVN following pub

222 of SHF-derived ECs to pharyngeal arches, the remodeling of endothelial plexus into the PAAs, and the

223 1) are neurotropic, and (2) cause structural remodeling of hippocampal dendrites.

224 of the heart, which results from electrical remodeling of individual pacemaker cells along with stru

225 Enterovirus infection induces the massive remodeling of intracellular membranes and the developmen

226 Further topological remodeling of light and dark zone follicular dendritic c

227 High glucose-induced remodeling of microtubule network facilitates robust GSI

228 godendrocytes can regulate the formation and remodeling of myelin sheaths and perhaps additional func

229 ting depression-like behaviors via dendritic remodeling of NAc D1-MSNs and may prove a useful target

230 Moreover, compressive loads stimulated remodeling of peritoneal mesothelial cell surface ultras

231 cremental and iterative, without substantial remodeling of pre-existing basal structures.

232 cific pattern of change, which reflected the remodeling of protein complexes involved in adaptation t

233 differentiation is accompanied by chromatin remodeling of specific loci to permanently silence genes

234 ng a critical function in loads transfer and remodeling of the alveolar bone.

235 ondrial antiviral signaling (MAVS)-dependent remodeling of the cell surface, increasing surface prese

236 in C. elegans epidermis during developmental remodeling of the cuticle.

237 or microenvironment, leading to an extensive remodeling of the ECM and an increased infiltration of C

238 cell proliferation, migration, adhesion, and remodeling of the extracellular matrix.

239 s of nonmalignant diseases associated with a remodeling of the extracellular matrix.

240 Biosynthesis and remodeling of the GPI anchor requires the activity of ov

241 n genome-wide recombination rate rather than remodeling of the local recombination landscape.

242 of endothelial plexus into the PAAs, and the remodeling of the PAAs into the aortic arch artery and i

243 Chronic hypoxia leads to pathologic remodeling of the pulmonary vasculature and pulmonary hy

244 Each stress induced rapid remodeling of the RNA-protein interactome without corres

245 might underlie distinctions in pathological remodeling of the RV in biventricular HF.

246 Longitudinal immune-monitoring reveals remodeling of the T-cell receptor repertoire with immuno

247 regeneration requires precisely coordinated remodeling of the transcriptional landscape to enable th

248 subsequently promotes tumor progression and remodeling of the tumor microenvironment (TME) by sustai

249 t drive proper epithelialization and stromal remodeling of the wounded area without the need for cade

250 at distinct classes of neurons individualize remodeling of their myelination profiles to diversify ci

251 ranscriptomic analysis, revealing a striking remodeling of transcripts involved in neuronal signaling

252 Stroke causes remodeling of vasculature surrounding the infarct, but w

253 onents to drive collagen fibrillogenesis and remodeling or by signaling through cell-surface integrin

254 al characteristics, left ventricular reverse remodeling, or outcomes on multivariable analysis (P=0.0

255 7 and BRD9, which form part of the chromatin remodeling PBAF and BAF complexes, respectively.

256 s then used as the initial condition for the remodeling phase during which regions healed into bone a

257 ng and marked gene alteration resembling the remodeling phase of wound healing, with increased matrix

258 Our findings suggest that HLTF promotes fork remodeling, preventing other mechanisms of replication s

259 ntains multipotent cells is involved in this remodeling process.

260 ts were regulated by T cells during the bone remodeling process.

261 the mechanisms of diverse cellular membrane remodeling processes.

262 r, the variants impair DAAM2-dependent actin remodeling processes: wild-type DAAM2 cDNA, but not cDNA

263 nistically, ZNF367 interacted with chromatin remodeling protein BRG1 and transcriptionally activated

264 lthough LSH belongs to a family of chromatin remodeling proteins, it remains unknown how LSH mediates

265 mains for multiple steps of the nucleic acid remodeling reactions.

266 olytic metabolism, collagen biosynthesis and remodeling, redox regulation and immunomodulatory protei

267 t microRNAs (miR-24-4, miR-21), cytoskeleton remodeling, response to stimuli, and inflammation can im

268 parent density with respect to a homeostatic remodeling stimulus.

269 , and CCL26 and genes associated with tissue remodeling, such as COL8A1, actin gamma-2 (ACTG2), and t

270 ith RNase P undergo an unexpected RNA-driven remodeling that allows them to bind to divergent RNAs.

271 on (PH) is characterized by pulmonary artery remodeling that can subsequently culminate in right hear

272 ological basis for chronic atrial myocardial remodeling that paves the way of atrial fibrillation.

273 h acts to drive progressive cell commitment, remodeling the epigenomic landscape to define the presum

274 hat STAT5 is the earliest factor binding and remodeling the Il9 locus to allow BATF binding in both m

275 whereby AML impairs normal hematopoiesis by remodeling the mesenchymal niche.

276 isoforms play a role in cardiac fibrosis and remodeling, the results are conflicting.

277 hMSCs can regulate arrhythmia substrates by remodeling their secretome in disease.

278 mitochondrial homeostasis, including cristae remodeling; therefore, we examined the photoreceptors of

279 ic rearrangements, contributing to oncogenic remodeling through chimeric circularization and reintegr

280 osin II filaments and a global change from a remodeling to a contractile state of the acto-myosin net

281 ge, improves cardiac function, and mitigates remodeling to a larger extent than when administered ora

282 amic array of filaments that undergoes rapid remodeling to drive many cellular processes.

283 cellular signaling cascades and cytoskeletal remodeling to support optimal inclusion development and

284 ult of a complex interplay between chromatin remodeling, transcription factors, and signaling molecul

285 the ANGPT2 N-terminal domain in blood vessel remodeling, tumor growth, metastasis, integrin binding,

286 at both neuron types show homeostatic myelin remodeling under normal vision.

287 gonism can attenuate aortic inflammation and remodeling via decreased smooth muscle cell activation a

288 ing cardiomyopathy, and cardiac function and remodeling was assessed by echocardiography 10 weeks aft

289 Previously, SWI/SNF chromatin remodeling was found to define the kinetics and selectiv

290 The only predictor of left ventricular remodeling was treatment with sonothrombolysis: the cont

291 hways associated with adhesion and molecular remodeling were also documented.

292 and tubulointerstitium identified early ECM remodeling, which may represent a new therapeutic opport

293 was more likely to exhibit left ventricular remodeling with an odds ratio of 2.79 ([95% CI, 0.13-6.8

294 n LVEDV and LVESV <12%]; group 3: adverse LV remodeling with compensation [>=12% increase in LVEDV on

295 ndamental to the study of heart function and remodeling with health and disease.

296 impaired relaxation and evoked hypertrophic remodeling with increased energetic stress.

297 but not mdxS3A, mice were resistant to Cx43 remodeling, with a corresponding reduction of Cx43 hemic

298 ogressive disease leads to pathologic tissue remodeling, with ensuing esophageal rigidity and loss of

299 tions cardiac lymphatics undergo significant remodeling, with insufficient lymphatic function and/or

300 chanical stress plays a major role in tissue remodeling, yet its role in diverticulosis has not been