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1 odistribution profiles with both hepatic and renal excretion.
2 arance from tissue compartments primarily by renal excretion.
3 e, unless the investigational agent involves renal excretion.
4  injection followed by a decline, indicating renal excretion.
5 a protein binding, a necessary condition for renal excretion.
6 and ultimate elimination of the K(+) load by renal excretion.
7 ydrodynamic diameter by >15 nm and prevented renal excretion.
8             18F-FB-[Lys3]BBN had predominant renal excretion.
9 e injected dose per gram]) and predominantly renal excretion.
10 ncomitant rapid disappearance from blood and renal excretion.
11 in very high for several days due to lack of renal excretion.
12 r, first-order process and that there was no renal excretion.
13  of the radiotracer from the blood and rapid renal excretion.
14 sue distribution and retention by preventing renal excretion.
15 minantly hepatobiliary clearance with modest renal excretion.
16 , DS exhibited a progressive increase in MBG renal excretion (66 +/-13 pmol/24 hours at week 4 versus
17            (68)Ga-NOTA-UBI-29-41 showed high renal excretion (83.2% +/- 7.3%) of injected dose and ra
18 ion and excrete from normal tissue/organ via renal excretion after complete targeting to the tumor si
19  function may have abnormal renal transit of renal excretion agents during exercise, although their b
20 bution in the abdomen and pelvis with little renal excretion and bladder activity-characteristics ben
21            Loss of Ttc30a impaired embryonic renal excretion and ciliogenesis because of altered post
22 s in preclinical studies, with predominantly renal excretion and good tumor-to-normal-tissue ratios.
23 ) is cleared intact into the bladder through renal excretion and has a prolonged blood half-life comp
24 efficacy of N-BPs is hampered by their rapid renal excretion and high affinity for bone.
25                               However, their renal excretion and retention are obstacles for applicat
26 above 15 mg kg(-1) : high dose expedited the renal excretion and shortened the blood retention.
27                                              Renal excretion and vasodilation did not account for the
28 ategories, namely, metabolic transformation, renal excretion, and hepatobiliary excretion.
29 .21 percentage injected dose per gram), fast renal excretion, and low background; tumor-to-blood and
30                       Diuresis, natriuresis, renal excretion, and tissue levels of MBG and OLC were m
31 rom blood, low hepatobiliary excretion, fast renal excretion, and very low uptake of (18)F activity i
32 ng and locally produced inhibitors; impaired renal excretion; and current therapies.
33                         Sulfoconjugation and renal excretion are important determinants of the wide i
34 ncreased efflux of bile acids into blood for renal excretion as well as hydroxylation of bile acids b
35 sing renal activity at 1-2 min (PETinitial), renal excretion at 2-10 min (PETearly), and, subsequentl
36 N) and (99m)Tc(CO)(3)(dd,ll-LAN) showed good renal excretion, averaging 85% and 77% that of (131)I-OI
37    Extracellular phosphate regulates its own renal excretion by eliciting concentration-dependent sec
38                              There is little renal excretion compared with (18)F-FDG.
39           It shows rapid blood clearance and renal excretion, enabling high contrast-to-noise imaging
40 lear phagocyte system (MPS) entrapment, fast renal excretion, endosomal escape, and off-target effect
41                                              Renal excretion fractions were measured from 10 to 14 di
42                                          The renal excretion fractions were measured from 12-24 discr
43                                    The 24-hr renal excretion fractions were measured from conjugate e
44 as kidney-specific biodistribution and rapid renal excretion (>80% injected dose in 4 h), compared to
45 alities of AuPC clusters combined with rapid renal excretion, high biocompatibility, and safety make
46 ac arrest and resuscitation, sepsis, reduced renal excretion, hypoxia induced cancer, decreased extra
47   Renal tubular reabsorption (RTR) following renal excretion is also common but not easily assessed.
48 t from the accumulation of metabolites whose renal excretion is coupled to uric acid reabsorption.
49                                Moreover, the renal excretion kinetic and intrahepatic albumin binding
50 d in 5-25% of the human population, impaired renal excretion leads to hyperuricemia.
51                                              Renal excretion of 8-iso PGF(2alpha) was increased in An
52 ent relies on fluid resuscitation to promote renal excretion of active metabolite, withholding the do
53 titution at the cleavage site resulted in no renal excretion of AIM.
54 lasma bile salt levels predominantly through renal excretion of bile products.
55 e, we conclude that strategies to accelerate renal excretion of bile salt and other toxins should be
56 testinal calcium may increase absorption and renal excretion of both phosphate and oxalate.
57 ngs and secondarily systemically followed by renal excretion of byproducts were the predominant elimi
58  wider range of values for serum calcium and renal excretion of calcium than we observe in control li
59 e kidney proximal tubule (PT) participate in renal excretion of drugs and endogenous compounds.
60                                              Renal excretion of imatinib was less than 10% of the tot
61 g for 1 wk decreased PMg++ 18%, TZR 25%, and renal excretion of magnesium (UMg) and calcium (UCa) mor
62 oximal tubule epithelial cells, mediates the renal excretion of many clinically important drugs.
63 uction is explained partly by the absence of renal excretion of metabolizable organic anions, leaving
64                                     Impaired renal excretion of NOx is a contributor to the high plas
65 a volume by at least 3 mechanisms: increased renal excretion of salt and water, vasodilation, and inc
66                                              Renal excretion of some prostate-specific membrane antig
67 ium excretion by the kidney is essential for renal excretion of sufficient amounts of protons and to
68 lthough the plasma clearance and the rate of renal excretion of the (99m)Tc(CO)(3)(LAN) complexes wer
69          Analysis of urine extracts revealed renal excretion of the cy-2-glu probe in the form of fre
70 he renal proximal tubule is critical for the renal excretion of the prototypic organic anion, para-am
71           These reactions result in enhanced renal excretion of the sulfate-conjugated reaction produ
72                               Because of the renal excretion of the tracer, the absorbed dose was hig
73 ne samples from patient studies showed rapid renal excretion of these radioactive cyclized species.
74 aminoguanidine (AG) can improve turnover and renal excretion of these substances.
75 rs and uncover a biochemical pathway for the renal excretion of this signaling metabolite.
76 mplicates them as substantial players in the renal excretion of urate.
77 sis of infected red blood cells and impaired renal excretion of uric acid were the primary drivers of
78  genes seem to be involved in regulating the renal excretion of uric acid which underscores the impor
79            These substances rapidly increase renal excretion or reduce renal tubular reabsorption and
80 ptake and urinary clearance, visualizing the renal excretion pathway from cortex to ureter.
81 ively, at 1 h after injection), indicating a renal excretion pathway.
82  from systemic blood circulation through the renal excretion route.
83 chanisms to achieve controlled and efficient renal excretion to improve potential clinical translatio
84 leading to enhanced tumor targeting and fast renal excretion to reduce toxicities.
85                               This defect in renal excretion was associated with a severe, PTH-induce
86 inetic parameters (solubility, permeability, renal excretion) were substantially improved by a bioiso
87 ly low activity and small size lead to rapid renal excretion when applied in vivo, limiting its thera
88 t showed rapid blood clearance and exclusive renal excretion, which provides a clear abdominal field
89  (CLP)-induced septic injury caused impaired renal excretion, which was improved in DHHC21 functional
90 PET imaging and biodistribution showed rapid renal excretion with low liver activity.
91 re eliminated completely through hepatic and renal excretion within four weeks of injection with no e
92 rest of the RNA nanoparticle were cleared by renal excretion within half hour after systemic injectio
93  can be easily cleared from the body through renal excretion without causing accumulation/toxicity pr