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1 in time, consequently, have to be updated or replaced.
3 threonine, tyrosine) code to systematically replace 29 membrane-facing leucine, isoleucine, valine,
4 re a short-term catch buffer large enough to replace ~43 +/- 35% of today's global animal protein pro
9 ective results reveal how lncRNA effectively replaces a DNA repair protein for efficient NHEJ with im
10 acceptor polymer (N2200), by systematically replacing a certain amount of alkyl side-chains with com
11 es including suppressing a specific thought, replacing a thought with a different one, and clearing t
12 ted lanthanide-doped MB structures that have replaced all the {Mo(2)} units with lanthanide ions on t
14 -chip (OOC) devices are miniaturized devices replacing animal models in drug discovery and toxicology
15 inted polymers (MIPs) have been developed to replace antibodies for the recognition of target molecul
16 Transradial intervention is increasingly replacing approaches, due to lower access complications,
17 water channels were developed with an aim to replace aquaporins for possible uses in water purificati
19 oft tissue substitutes have been proposed to replace autogenous connective tissue grafts, therefore t
21 de as much granularity as possible, e.g., by replacing bar graphs with scatter plots wherever feasibl
24 urgeries and multidisciplinary management to replace bone and soft tissues, as well as restore esthet
25 values <= 35 for unamplified cDNA) had to be replaced by (3) proofing linear pre-amplification for ea
26 like motif bridging the two thienyl units is replaced by a benzene motif, and show that this compound
27 d to elute the NAs off the magnetic beads is replaced by a carefully selected PCR solution, enabling
28 th a single-rooted tooth to be extracted and replaced by a dental implant were recruited for this stu
29 s in which one of the benzene rings has been replaced by a different (4n + 2) pai-electron system hav
30 se macrophages disappear after birth and are replaced by a dynamic mixture of macrophage subtypes, de
31 by a single bond, which could potentially be replaced by a fused aromatic ring to enhance the rigidit
33 l oxidative addition (OA) mechanism has been replaced by a halogen abstraction-radical capture (HARC)
35 s unnecessary to prevent errors and could be replaced by a rejection comment specifying clinical situ
37 In the simpler young wine model, V1 could be replaced by a vector containing just 3 odorants (ethyl 2
38 imaging revealed that caudal vertebrae were replaced by a ventrally-positioned, unsegmented endoskel
39 over across the early warming phase and were replaced by a virtually monotypic assemblage of a smalle
40 he nonpolymerizing fetal hemoglobin has been replaced by adult hemoglobin S at about 1 y after birth.
41 l-binding site of the polymerase domain were replaced by alanine is highly toxic to E. coli cells.
45 that the amino acid asparagine 285, which is replaced by an aspartate residue in type P(O) SadP, was
47 ly from late embryonic precursors and become replaced by bone-marrow-derived macrophages over time.
48 healthy Lactobacillus-dominant microflora is replaced by BV-associated bacteria (BVAB), can significa
51 CTA2/CTB) in which the CTA1 domain of CT was replaced by dsc(19)CfaE that was strongly immunogenic wh
52 eologous pairing is gradually eliminated and replaced by exclusive homologous pairing in well-establi
54 of drugs on a compassionate basis should be replaced by highly powered, multi-centre, multi-arm clin
55 gan to resolve, and eventually this area was replaced by hyperreflective, irregular, knobbly elevatio
56 ominated response in the pretransplant group replaced by IL-10-dominated response in the 1-6 m posttr
57 ion and follicle cell differentiation can be replaced by its mouse homolog steroidogenic factor 1 (mS
58 ription factor TATA binding protein (TBP) is replaced by its paralogue, TBPL2 (TBP2 or TRF3), which i
61 ecies with small geographic ranges are being replaced by more widely distributed species, and our res
66 ions from South America will be increasingly replaced by open savanna species, a phenomenon we name "
67 that olivine in this sample has been partly replaced by orthopyroxene, troilite, and minor metal.
68 h potential adverse health effects are being replaced by other phthalates or phthalate alternatives.
70 ibacterium) at the surgical site, which were replaced by potential pathogens and intestinal anaerobes
71 nally residing in the N(2) S(2) (4-) pocket, replaced by protonation at the amido nitrogens, generati
74 a redox-insensitive mutant in which C674 is replaced by serine (C674S) were exposed to H(2)O(2) (100
75 nd thus costly experimental studies could be replaced by simulations for movement analysis and virtua
77 These lineages may have been evolutionarily replaced by the ecological revolution launched by angios
78 nding RTX domain of CyaA can be functionally replaced by the HlyC-acylated segment and the much short
81 nosoma brucei the function of Pam18 has been replaced by the non-orthologous euglenozoan-specific J-p
82 s containing the zinc-binding CXXC motif are replaced by their motif-free paralogues, collectively ca
85 conversion in state where ZEB2 expression is replaced by ZEB1 expression associated with gain of an i
86 reate alternative drivers of INS expression, replacing canonical PDX1-driven beta cell specification
88 ease in global energy demand and the need to replace carbon dioxide (CO(2))-emitting fossil fuels wit
91 demic healthcare centre, we examined whether replacing CO(Fick) in the Gorlin formula with Cheetah-NI
92 suggest that temperate adapted bacteria may replace cold water taxa under a future scenario of incre
93 Low calorie foods are products designed to replace complete meals or to control snacking in many hy
94 FA may serve a role as a rapid test that may replace conventional GM testing in settings where GM res
95 maize meal with SA and has the potential to replace conventional HMT in the development of lower GI,
97 a higher proportion of HCT recipients after replacing conventional stool testing with a multiplexed
98 Additionally, distinct histone variants can replace core histones to regulate chromatin structure an
100 realm of diagnostic methods to complement or replace current culture-based and molecular microbiologi
101 ion, this method can augment and potentially replace current dissolution tests and support product de
103 separation methods based on physisorption to replace currently used energy-intensive distillation/abs
104 abolic proteins, including as selenocysteine-replacing cysteine at position 253 in uncoupling protein
105 n's disease (PD) aim to delay progression or replace damaged neurons by restoring the original neuron
108 dy failed to find evidence that medical POHS replaced dental visits for young children enrolled in Me
109 ph, Noctiluca scintillans which has recently replaced diatoms as the dominant winter, bloom forming o
110 within benchmarks when synthetic mammography replaces digital mammography in digital breast tomosynth
111 100 years of forest regrowth following stand-replacing disturbance, asking (a) Which processes and pa
112 nce of these engineered receptors, GFP could replace Dpp to organize patterning and growth in vivo.
113 n vivo studies, the M. tuberculosis Tam also replaced E. coli BioC both in vivo and in vitro and comp
115 polyploid PCs are outnumbered by RSCs, which replace each lost cell with multiple PCs of lower ploidy
118 disease, we engineered C57BL/6J (B6) mice to replace endogenous murine Cr2 with human complement rece
123 rom the scientific literature, and partially replace expert curation, but such machine learning frame
126 tudy aimed to determine if it is possible to replace FO by a mixture of FO and rapeseed oil (RO) with
127 ve been considered as promising organisms to replace fossil resources with contemporary primary produ
129 alt in enrolled households was retrieved and replaced, free of charge, with a combination of 75% NaCl
130 d turnover of the GBM improves, therapies to replace GBM components or to stimulate GBM repair could
131 that undergoes RNA editing in GluA2 subunits replacing glutamine to arginine, with the percent inhibi
132 ith land degradation via xerification, which replaces grasses with shrubs and bare soil patches.
133 (moderate) CVD risk than the population mean replaced habitual dairy products with study products (mi
134 oxides as starting materials and effectively replaces harsh fluorinating reagents by a combination of
135 of trabecular bone and collagen fibers that replace hematopoietic cells, resulting in abnormal bone
138 that deep learning may have the potential to replace humans in applications where conservation of mea
139 or lost post-duplication, we systematically replaced hundreds of essential yeast genes with their hu
142 multipotent basal stem cells (BSCs) that are replaced in adult life by distinct pools of unipotent st
143 loro-2-pyridylmethyl)amine (TPMA(3Cl) ) were replaced in one step and high yield by electron-donating
144 material combined during manufacturing would replace injectable defect fillers (cements) and allow pe
145 diomyocytes can affect "heart regeneration", replacing injured cardiac scar tissue with concomitant e
148 ing mitosis, CRL4 dissociates from RepID and replaces it with RB Binding Protein 7 (RBBP7), which ubi
149 associate a tone with a strong footshock by replacing it with a much weaker one during memory retrie
150 emonstrating that when only one ortholog can replace its corresponding yeast equivalent, it tends to
151 imary structure of yeast cyclophilin CPR1 by replacing its homologous sequence resulted in a hybrid m
153 ights into IVIg activity brought the goal of replacing IVIg within reach, at least in select indicati
159 er and potent alternative mucosal vaccine to replace live vaccines against IBV and other emerging cor
160 ring the last glacial maximum (LGM)(1-3) and replaced local wolf populations.(4) Moreover, ancient ge
161 generation is the process by which organisms replace lost or damaged tissue, and regenerative capacit
162 been introduced in hybrid SPECT/CT systems, replacing low-end x-ray tubes with high-end multislice C
163 ively charged lysine 319 residue on TM2, and replacing lysine 319 with a glutamate residue converts P
164 ound that granulocytes and monocytes rapidly replaced macrophages and dendritic cells in tumors follo
165 tion by spray drying was evaluated partially replacing maltodextrin (13.5% w/w dry matter) and totall
166 gans fitness, there is an increasing need to replace manual assessments of worm motility with automat
168 one-third (37.6%) of the respondents did not replace mask when it had been used for more than 8 hours
170 nvasiveness of the test, with an interest in replacing multiple diagnostic methods with one powerful
171 d mild fibrosis (n = 8) in the endomysium or replacing muscle fibers, with no granulomas or vasculiti
173 s is to utilize stem and progenitor cells to replace neurons in situ, with the expectation that new n
174 red structures, durability, and functions to replace nonrenewable plastics, polymers, and metals.
175 larizing agonists varied in their ability to replace OCH as the initial hit, with their lipid chain l
176 elminth interactions with their hosts and to replace or reduce the dependence on using animal models.
177 aceuticals, provide the potential for either replacing or complementing (18)F-FDG PET/CT in the selec
178 as a promising energy storage technology to replace organic liquid electrolyte-dominated Li-ion batt
181 ed production technologies may complement or replace petroleum-based production of chemicals, but the
182 (Fe-N-C) materials are leading candidates to replace platinum catalysts for the oxygen reduction reac
183 henyl)amine (PTAA)) is employed to partially replace polymer donors in the active layer of PBDB-T/Y1.
184 local conformational changes not only in the replaced positions but also on their neighbor residues o
185 n alternative, discrete, representation that replaces positions (points and distances) with niches (b
186 mate when determining the best locations for replacing power plants with new wind, solar, or natural
187 he SAFER Reporting Framework is not meant to replace previous research reporting guidelines, but rath
193 eptide mapping can, in principle, adequately replace selected QC methods and would add value to the i
196 oped over a number of cooking events and are replaced slowly over time, with little evidence of the f
197 bling technology for asymmetric synthesis to replace some aspects of conventional batch electrochemic
198 ng enables new types of imaging systems that replace standard optical components like lenses with cle
200 arent and non-toxic alternative front layers replacing state-of-the-art CdS in Cu(In,Ga)Se(2) thin-fi
201 rosyntheses create the unique possibility to replace stoichiometric amounts of oxidizing or reducing
203 arch of antioxidants and natural pigments to replace synthetic molecules is increasingly considering
207 uch functionalized composites can be used to replace the common heavyweight materials used for microw
208 utants, were able to effectively compete and replace the defective myelin (n = 2 at each of four end
209 split lens is designed to be small enough to replace the entrance lens of a Bruker FT-ICR collision c
213 rates and thus MALDI-TOF MS might be able to replace the LB agar colony to evaluate the photodynamic
214 lternative approaches have been developed to replace the linear reference with a variation graph whic
216 rp73 gene, we selectively engineered mice to replace the most abundantly expressed C-terminal isoform
219 ts have been realized by using memristors to replace the static random-access memory cell in conventi
221 functionally assess both TOMM70 variants, we replaced the Drosophila Tom70 coding region with a Kozak
225 mapping of blochnium onto a transmon, which replaces the external flux by the offset charge and intr
227 ide (DMSO) into ZnCl(2)-H(2)O, in which DMSO replaces the H(2)O in Zn(2+) solvation sheath due to a h
228 ing networks: (1) a "local" framework, which replaces the hard integrate-and-fire spiking rule within
229 tion and because a single-stranded donor DNA replaces the original allele, transformation efficiency
232 ogel-based vascular model was developed that replaces the ubiquitous fluorescent tracer with an elect
235 urosteroid analogues with diazirine moieties replacing the 3-hydroxyl (KK148 and KK150) bind to all t
236 ANT3310, which uniquely has a fluorine atom replacing the carboxamide and stands apart from the curr
237 ough there has been near-uniform support for replacing the eligible death denominator with CDC data,
238 The utility of our system is demonstrated by replacing the enzymatically biased RNA-to-DNA reverse tr
240 evealed that, contrary to a previous report, replacing the ester bond with an amide bond significantl
241 Further improvements were realized upon replacing the ether-linked amines with carbon-linked mor
243 initially stimulated microbial growth by (i) replacing the function of enzymes that degrade higher mo
246 r, a chimeric virus ( XG4J) was generated by replacing the indigenous X174 J gene with that of G4.
247 r UFP) for two study areas in Boston (MA) by replacing the measured PNC term with an hourly model and
248 ctric layer for the excitation of LRSP modes replacing the most explored Cytop and Teflon polymers.
249 severe, murine model of C3G was developed by replacing the mouse C3 gene with the human C3 homolog us
251 trom X-ray structure of kappaOR-MP1104 after replacing the nanobody with the activated Gi protein and
252 culture of intestinal organoids, potentially replacing the need for animal-derived matrices, while al
254 ta analysis has been unveiled (version 5.0), replacing the previous single pipeline with multiple ana
255 obutyric acid (DABA), or serine, effectively replacing the ring-closing ester bond with an amide link
257 generated a mouse model of this condition by replacing the wild type gene with one encoding Kcnt1(R45
258 ,13-epoxide and macrolactam NH moieties were replaced, the former with a substituted aziridine moiety
259 ote the expansion of haematopoietic cells to replace their homologous (allelic) counterparts, increas
261 receptor (hMET) into glutamate receptors by replacing their extracellular binding domains with the l
264 e allotransplantation (VCA) has appeared for replacing tissue defects in patients for whom no other s
265 ells are preferentially depleted, and can be replaced to promote spermatogenesis from surviving (host
269 s enumerated herein afford opportunities for replacing traditional rare-metal-based emitters for sola
270 shifted toward more xeric communities, with replacing tree and shrub species exhibiting drier biocli
273 of these lysines to arginine and found that replacing two of these residues, Lys-1155 and Lys-1230,
274 pose a Bayesian inference framework based on replacing uninteresting or unobserved reactions with tim
277 ect oral anticoagulants (DOACs) have largely replaced vitamin K antagonists in many indications for a
279 half of the Northern Levantine gene pool was replaced, while in the rest of Anatolia and the Southern
283 he Y15A and Y15G variants in which Tyr-15 is replaced with Ala or Gly, respectively, are monomeric.
286 hich the largest RFC subunit, RFC1, has been replaced with ATAD5 (ELG1 in Saccharomyces cerevisiae).
289 idue involved in the depsi (ester) bond, was replaced with either diaminopropionic acid (DAPA), (2S,3
290 nd suckling deficits in infants with PWS are replaced with excessive feeding and obesity in childhood
291 gene array in which all H3-H4 promoters were replaced with H2a-H2b promoters (12x(PR)) does not form
292 phthalate (DEHP), are now increasingly being replaced with more environmentally friendly alternatives
294 Cellular selenocysteines, where sulfur is replaced with selenium, exhibit enhanced reactivity with
295 e Cys axial ligand to the heme iron has been replaced with Ser) generated variants that selectively f
296 of fish meal (FM) protein in aquafeeds being replaced with soybean meal (SBM) protein, understanding
297 ional three dimensional MR scalar images are replaced with spatially resolved multidimensional spectr
298 observed when the benzamide derivatives are replaced with trifluoroacetamide, causing an additional
299 re deployments are based on repowering (i.e. replacing with higher capacity WTs) thus avoiding compet
300 cant, inhibits erythropoiesis likely through replacing zinc within the zinc fingers of the critical t