ライフサイエンスコーパス: repletion

1 a2+ depletion followed by 10 minutes of Ca2+ repletion).

2 simple approach to prevention (i.e., SNO-Hb repletion).

3 of the motor unit, arguing for systemic SMN repletion.

4 ular cycles of nutrient scarcity followed by repletion.

5 on, which were reversible by subsequent zinc repletion.

6 ly released into the cytoplasm after glucose repletion.

7 hich could be subsequently restored by lipid repletion.

8 of the host and was restored after androgen repletion.

9 nd neonatal iron deficiency, even after iron repletion.

10 food source capable of restoring fatty acid repletion.

11 of cirrhosis that does not respond to volume repletion.

12 oping hippocampus that persists despite iron repletion.

13 hearts, returning to WT levels after leptin repletion.

14 does not appear to be down-regulated by zinc repletion.

15 n ERKs, which was restored after cholesterol repletion.

16 s mellitus resolved after 6 weeks of thiamin repletion.

17 amage were also observed following vitamin C repletion.

18 the two earlier time points) or 4 days after repletion.

19 form distribution is restored by cholesterol repletion.

20 nd accelerate post-exercise (liver) glycogen repletion.

21 ituation of NOS inhibition coupled with cGMP repletion.

22 5 matched controls before and after glycogen repletion.

23 ; P < 0.01) and was not affected by glycogen repletion.

24 rats; it is rapidly recovered after retinol repletion.

25 and urinary copper increased in response to repletion.

26 moglobin, but did not increase during copper repletion.

27 increased to 1000 U/g protein during copper repletion.

28 on but ceruloplasmin decreased during copper repletion.

29 copper depletion, then dropped during copper repletion.

30 pes, there was no benefit from adult torsinA repletion.

31 contributing to hepcidin suppression and Hb repletion.

32 activity and rescued in EoE using adenosine repletion.

33 ncreatitis that was ameliorated by phosphate repletion.

34 mouse colon, which was rescued with butyrate repletion.

35 .9 mmol . d(-1); time x condition: P = 0.45) repletion.

36 at may be prevented by gestational vitamin D repletion.

37 pathway(s) associated with hepatic glycogen repletion.

38 ghly sensitive biomarker of effective NAD(+) repletion.

39 egion of shu1(+) in vivo in response to iron repletion.

40 placed on 36 subjects and allowed to feed to repletion.

41 was also reduced in mice with angiopoietin-1 repletion.

42 should be tested in guiding tailored volume repletion.

43 ly suggesting reduced inflammation with iron repletion.

44 iest genes activated in response to nutrient repletion.

45 iron on a regular schedule to maintain iron repletion.

46 recycled to the plasma membrane upon Ca(2+) repletion.

47 etic dysfunction - were mitigated by choline repletion.

48 during reduced-weight maintenance and leptin repletion.

49 ng, and not simply a Ca(2+) source for store repletion.

50 ors were then randomized to intravenous iron repletion (1 g low-molecular-weight iron dextran) or pla

51 g Zn/d for 1 wk and 4 mg Zn/d for 5 wk), and repletion (11 mg Zn/d for 4 wk with 20 mg supplemental Z

52 Iron repletion (15 microM) and copper starvation drastically

53 t (10 microg/d) for 15 d followed by 10 d of repletion (200 microg/d) with either phylloquinone or di

54 s of Ca2+ depletion (1 minute each) and Ca2+ repletion (5 minutes each).

55 towards the activity found in WT with leptin repletion, a finding that could account for impaired bet

56 innate immune responses, but whether 25(OH)D repletion affects vitamin D-responsive monocyte pathways

57 )] prion allows yeast to anticipate nutrient repletion after periods of starvation, providing a stron

58 after therapy with the recommended vitamin D repletion algorithm.

59 oli cell tight junction barrier, but calcium repletion allowed the "resealing" of the disrupted barri

60 NAD repletion also prevented loss of the transcriptional reg

61 Plasma gelsolin repletion also shifted the cytokine profile of endotoxem

62 so examined whether caudal hindbrain lactate repletion alters the impact of hypoglycemia on substrate

63 Consensus on the definitions of iron repletion and excess stores, as well as on ID and IDA, i

64 ildhood and in characterizing states of iron repletion and excess.

65 lpha12-MDCK) were subjected to ATP depletion/repletion and H(2)O(2)/catalase as models of tight junct

66 esulted in biochemical evidence of cobalamin repletion and improvement in motor function and regurgit

67 recovery period to facilitate rapid glycogen repletion and muscle remodelling.

68 rum Pi content and muscle VATP After oral Pi repletion and normalization of serum Pi levels, muscle V

69 is the major pathway for neuronal glutamate repletion and that the astroglial TCA cycle flux (0.14 +

70 However, a functional link between NAD(+) repletion and the delicate duo of IH and EC regeneration

71 in B31 were fed on mice for 48 or 96 h or to repletion and then crushed and acetone fixed either imme

72 ycles after a shorter period of testosterone repletion, and a longer duration of testosterone depleti

73 we describe the prevalence of ID, IDA, iron repletion, and excess stores with the use of published d

74 dly dissociated from polysomes after glucose repletion, and sequences bound by RNA binding proteins w

75 light; (iii) exponential growth and nutrient repletion; and (iv) stationary phase and nutrient deplet

76 Despite attempts at volume repletion, antimicrobial therapy, and limited laboratory

77 However, repletion assays demonstrated that the mechanism of acti

78 24-h intervals following attachment through repletion at 96 h, and spirochetes were stained for immu

79 Iron repletion augments exercise capacity in chronic heart fa

80 the absence of established cutoffs for iron repletion based on TBI.

81 isk, and our data suggest that screening and repletion be considered in patients scheduled for cardia

82 deficiency risk among Black women, vitamin D repletion before or in early pregnancy may be an importa

83 o cyanophycin during nitrogen limitation and repletion, both with or without inhibition of protein sy

84 mycophenolic acid and was restored upon GTP repletion by coprovision of guanosine.

85 duced, and both responses were restored upon repletion by PMN obtained from WT mice but not by PMNs f

86 late barrier function, and that testosterone repletion can have negative consequences for permeabilit

87 Dietary iron repletion completely reversed ID anemia and ineffective

88 e depletion conditions, and finally to store repletion conditions.

89 ore be an important mechanism via which iron repletion confers benefits in chronic HF despite minimal

90 We studied whether vitamin D repletion could correct aberrant adipose tissue and musc

91 0.05), changes that were ameliorated by zinc repletion (day 55 compared with day 83; P < 0.05).

92 d for 1 wk and 4 mg Zn/d for 5 wk), and zinc repletion (days 56 to 83; 11 mg Zn/d for 4 wk with 20 mg

93 weights of fed ticks and percentage reaching repletion did not indicate development of acquired resis

94 cholesterol depletion alone, as cholesterol repletion did not reverse amitriptyline's effect.

95 e demonstrate through a controlled depletion/repletion dietary protocol that the illusive zinc biomar

96 The slow response to the repletion diets observed suggests that normalization of

97 with chronic HF and iron deficiency, a total repletion dose of iron isomaltoside given at a single si

98 tamin C per total study days, was 88-98% per repletion dose.

99 are unit stay, electrolyte abnormalities and repletion doses, duration of inotropic administration, a

100 rom 4 to 6% when derived from females fed to repletion during acute parasitemia.

101 r larval progeny derived from females fed to repletion during persistent or acute infection.

102 However, maternal vitamin D repletion during pregnancy has not yet been proven to im

103 In contrast, leptin repletion during this period of starvation has little or

104 Retinol repletion effected a full recovery.

105 we describe the rationale for the Oral Iron Repletion effects on Oxygen Uptake in Heart Failure (IRO

106 was demonstrated in cell culture anoxia/ATP repletion experiments as a model of I/R.

107 TAM depletion-repletion experiments in a 4T1 mouse model additionally

108 Patients had more feelings of repletion, flatulence, intestinal murmurs, and burping (

109 sis, which consisted of intravascular volume repletion followed by vasopressor administration titrate

110 nt obese subjects, we have shown that leptin repletion following a 10% or greater weight loss reduces

111 tivity of cerebral arterioles, and that cGMP repletion, following NOS inhibition, could restore CO2 r

112 ion for 21 d, and 2.06 mg/d during the third repletion for 14 d.

113 pletion for 27 d, 1.26 mg/d during the first repletion for 21 d, 1.66 mg/d during the second repletio

114 letion for 21 d, 1.66 mg/d during the second repletion for 21 d, and 2.06 mg/d during the third reple

115 Some of the -A mice were given retinol repletion for 7 days (-A+A).

116 With combined NADPH and BH4 repletion, full restoration of NOS-dependent coronary fl

117 Cholesterol repletion fully reversed the effect of methyl beta-cyclo

118 'Biome repletion' has emerged as a potential therapeutic approa

119 inical algorithm including response to fluid repletion, history, physical examination, and urine dips

120 Folate repletion improves survival in 5-FU-treated animals.

121 0-wk, double-blind, controlled trial of zinc repletion in 740 urban, 6-9-y-old first graders from low

122 and supports the critical role of fibrinogen repletion in bleeding patients.

123 tested the hypothesis that intravenous iron repletion in chronic HF enhances skeletal muscle energet

124 Furthermore, angiopoietin-1 repletion in diabetic mice increased Tie-2 phosphorylati

125 lowing symptom onset can be effective; Glut1 repletion in early-symptomatic mutants that have experie

126 petus for clinical evaluation of glutathione repletion in PD.

127 in rats and humans, we showed that chloride repletion in the face of persisting alkali loading, volu

128 king clinical research into the role of iron repletion in this condition over the last 20 years.

129 eath, further supporting the benefit of iron repletion in this population.

130 We therefore hypothesized that enhancing GTP repletion in vivo might protect function by reducing apo

131 shed pathways for neurotransmitter glutamate repletion indicates that the glutamate/glutamine neurotr

132 In budding yeast cells, nutrient repletion induces rapid exit from quiescence and entry i

133 determine whether vitamin B-6 depletion and repletion influence carnitine concentrations in the plas

134 apidly deplete brain iron concentrations and repletion is able to normalize them.

135 tes these adverse associations, preoperative repletion is low cost and low risk, and our data suggest

136 Our data suggest that if nutritional repletion is possible in patients with end-stage liver d

137 rimary hypothesis that triiodothyronine (T3) repletion is safe in this population and produces improv

138 atially heterogeneous glycogen depletion and repletion kinetics that correlated with the severity of

139 t AA deficiency, compared with subsequent AA repletion, led to oxidative stress (using malondialdehyd

140 Vitamin D repletion may be an effective therapeutic strategy for a

141 Mg repletion may be an important ancillary therapy in hypom

142 nse to hypoxia, and they suggest that SNO-Hb repletion may improve transfusion efficacy.

143 Timely Glut1 repletion may thus constitute an effective treatment for

144 in the growth medium and 15N labeled in the repletion medium, allows the determination of the source

145 dence supporting the role of targeted NAD(+) repletion nanotherapy in managing restenosis and improvi

146 Importantly, vitamin D repletion normalized the expression of those 12 genes in

147 Glycogen repletion normalized the rate of gluconeogenesis.

148 In the presence of CGP77675 after Ca(2+) repletion, occludin tyrosine phosphorylation was complet

149 Upon calcium repletion, occludin, zonula occludens 1, and E-cadherin

150 and was reversibly restored with the in vivo repletion of 1,25(OH)2D3.

151 lative anaphylaxis risk following total iron repletion of 1000 mg administered within a 12-week perio

152 nder tail posterior lobe also benefited from repletion of a more subtle granule cell deficiency.) Don

153 ores resistance to autoimmunity and leads to repletion of a T cell subset (RT6.1) in the recipients.

154 Podocyte-specific inducible repletion of angiopoietin-1 in diabetic mice caused a 70

155 In the absence of a normal microbiome, repletion of bacterially-derived SCFA metabolites revers

156 a mouse cocaine place preference model, and repletion of bacterially-derived short-chain fatty acid

157 in the absence of calcium for 10 min before repletion of calcium resulted in no increase in neutroph

158 ircular dichroism, and was irreversible with repletion of calcium.

159 Repletion of CD8(-/-) mice with wild-type or perforin(-/

160 These changes were reversed with repletion of cell ATP.

161 Repletion of cellular cholesterol levels, which was know

162 induced by PARP activation was prevented by repletion of cellular NAD levels either by adding NAD di

163 /2 activation but not STAT5 phosphorylation; repletion of cholesterol in mbetaCD-treated cells restor

164 Repletion of cholesterol restored the sensitivity of ade

165 he MbetaCD effect was completely reversed by repletion of cholesterol, but not by an inactive analog

166 l resulted in reduced toxin binding, whereas repletion of cholesterol-depleted cells restored binding

167 Repletion of cholesterol-depleted cells with cholesterol

168 iation of MDA-MB-231 cells were prevented by repletion of CTP through the cytidine salvage pathway.

169 r multiple fates might differentiate towards repletion of deficient cell types, a possible developmen

170 Repletion of extracellular Ca(2+) to cells stimulated wi

171 Better repletion of factors V, VIII, and IX was seen longitudin

172 Folate or nucleoside repletion of folate-deficient cells rapidly restored T l

173 generation of nitrite and nitric oxide--and repletion of formula with sodium nitrate/nitrite restore

174 refeeding after TPN is associated with rapid repletion of GALT cellularity, initially within Peyer's

175 Moreover, repletion of GGPP, which prevented acute zoledronate tox

176 The repletion of GH/IGF-I levels in aging individuals is sug

177 Last, adenoviral repletion of hepatic ABCA1 in HSKO mice normalized plasm

178 which is most likely a result of the faster repletion of hepatic GSH.

179 t-induced hepatic UPR activation, likely via repletion of hepatic SAM.

180 Repletion of IFN-gamma to the system restored NO product

181 bated by administration of IFN-beta, whereas repletion of IFN-gamma, as well as therapeutic targeting

182 nd either fructose or glucose elicit similar repletion of IMCLs and muscle glycogen.

183 social deficits were reversible by intra-PFC repletion of interferon cytokines.

184 ease is almost completely restored following repletion of intracellular BH4 levels by incubation of t

185 onse but rather was derived from the partial repletion of intracellular Ca2+ stores.

186 However, the repletion of intracellular potassium stores could avoid

187 Repletion of intracellular SNO levels with SNO donor com

188 Repletion of lean body mass (LBM) that patients lose in

189 types and their response to LPS; cholesterol repletion of macrophages resulted in increased cellular

190 ad engraftment throughout the shi brain with repletion of MBP.

191 signaling to ERK and c-Fos were rescued upon repletion of membrane cholesterol.

192 Repletion of mitochondrial CoQ within the Fmr1 KO forebr

193 by lysosomes (i.e., autophagy), followed by repletion of mitochondrial populations.

194 otein, and either fructose or glucose on the repletion of muscle energy stores over 24 h after a stre

195 Previously, we have shown that repletion of Na,K-ATPase beta1-subunit (Na,K-beta) in hi

196 Repletion of NADPH after I/R increased NOS-dependent cor

197 ment approaches for this disorder, including repletion of natural circulating anticoagulants, use of

198 by providing a source of nucleotides for the repletion of nucleotide pools.

199 Repletion of plasma gelsolin leads to solubilization of

200 of infection enhances host defense and that repletion of PMN, as well as promoting PMN influx by CXC

201 mice with serum from wild-type (WT) mice and repletion of Rag1(-/-) mice with B cells improves sepsis

202 e, renewing speculation about when and where repletion of SMN is necessary for optimal outcomes in SM

203 n of coagulopathy, and earlier and prolonged repletion of some but not all procoagulant factors.

204 on with marked decline of Proteobacteria and repletion of spore-forming Firmicutes, as compared with

205 Repletion of T cell-deficient mice with either CD4(+)CD2

206 Repletion of TCR-betaxdelta(-/-) mice with Th17 cells fr

207 These results suggest that repletion of the albumin pool of children with PEM is no

208 r recovery in aged epidermis correlates with repletion of the extracellular spaces with normal lamell

209 1 reveal that pre-symptomatic, AAV9-mediated repletion of the protein averts brain microvasculature d

210 Repletion of this isoform of Agrin in the motor neurons

211 Additionally, repletion of TNF-alpha(-/-) mice with TNF-alpha(+/+) CD8

212 lls but not with TNFR2 KO CD8(+) T cells and repletion of TNFR1 KO mice with either WT or TNFR1 KO CD

213 Repletion of TNFR2 KO mice with WT CD8(+) T cells but no

214 Excess exogenous queuine can cause repletion of tRNA queuine levels in RasC4 cells.

215 Repletion of vitamin D and suppression of parathyroid ho

216 Furthermore, repletion of vitamin D improved skeletal muscle fiber si

217 This suggests that repletion of vitamin D may have benefits beyond bone hea

218 Repletion of XPF restored sensitivity comparable with th

219 creased mortality and that acute nutritional repletion of zinc would be beneficial.

220 left to rest for 4 weeks (Group I) or fed to repletion on a mouse (Group II).

221 tes in the feeding ticks, since ticks fed to repletion on B. burgdorferi-pulsed dendritic cell-sensit

222 ed the effects of dietary zinc depletion and repletion on DNA strand breaks, oxidative stress, and an

223 cks from each cohort were allowed to feed to repletion on either white-footed (Peromyscus leucopus) o

224 in humans by examining the effects of leptin repletion on feeding behavior after weight loss.

225 moderate folate depletion followed by folate repletion on leukocyte genomic DNA methylation was inves

226 om 0 to 20% when derived from females fed to repletion on persistently infected calves and from 4 to

227 3-day-fed larvae derived from females fed to repletion on persistently infected cattle.

228 ency and 1,25-vitamin D3 and 1,25-vitamin D2 repletion on proteinuria could not be explained by hypoc

229 To assess the effect of NAD(+) repletion on the development of steatosis in mice, nicot

230 r tetrahydrobiopterin (BH4) is depleted, its repletion only partially restores eNOS-mediated coronary

231 occurs in diseases with redox stress, BH(4) repletion only partly restores NOS activity and NOS-depe

232 ventilated patients (p < 0.01), electrolyte repletion (p < .01), initiation of physical therapy (p <

233 th depletion (P < 0.0001) and decreased with repletion (P < 0.0001).

234 E was associated with reticulocytosis and Hb repletion (P< .01).

235 be considered in the context of a depletion-repletion paradigm and suggest that low flavanol consump

236 Dopamine repletion partially restored this response in PD patient

237 hyl incorporation in any group over the 7-wk repletion period compared with postdepletion values.

238 .57 mg) Cu/d for 105 d, followed by a copper-repletion period of 35 d during which the diet was suppl

239 14, and 28 (depletion phase) and 44 and 65 (repletion phase).

240 tions from the diet during the depletion and repletion phase.

241 s exhibited reduced rates of muscle glycogen repletion post-exercise.

242 RNA polymerase exhibited a similar depletion-repletion profile, suggesting that the mitochondrial tra

243 yses was applied to a dietary zinc depletion/repletion protocol with young male human subjects.

244 Short-term zinc repletion provides significant, but incomplete protectio

245 so accelerate post-exercise (liver) glycogen repletion rates, which may be relevant when rapid (<24 h

246 and the currently recommended ergocalciferol repletion regimen often does not fully correct vitamin D

247 t little data exist in support of an optimal repletion regimen.

248 At the organismal level, NAD(+) repletion remarkably extends lifespan and delays acceler

249 after dietary phylloquinone restriction and repletion, respectively.

250 In the permeabilized cell system, energy repletion restored beta-VLDL-induced cholesterol esterif

251 NAD(+) repletion restores NAD(+) metabolic profiles and improve

252 SR Ca(2+) depletion reduces HR and SR Ca(2+) repletion restores physiological SANC rate responses, de

253 Importantly, cholesterol repletion restores receptor phosphorylation together wit

254 medullary tip after 7 d, whereas aldosterone repletion reversed the effect.

255 IRF4 knockdown recapitulated, whereas IRF4 repletion reversed, the anti-proliferative phenotype of

256 main on the host for up to 7 days to feed to repletion, secrete immunosuppressive proteins.

257 Nutritional repletion should thus be based on MEE to avoid the probl

258 y in cells lacking TARS2 is resistant to Thr repletion, showing that TARS2 is necessary for Thr-depen

259 reward-driven appetite to override metabolic repletion signals in presatiated rats.

260 ated Tregs and Scurfy lymph node cells; Treg repletion significantly attenuated IRI-induced renal inj

261 f episodes of pump blockade allowed [Na](SL) repletion, since peak postblockade I(pump) exceeded I(pu

262 and PD patients, regardless of baseline iron repletion status or C-reactive protein level and with or

263 l within 7 weeks regardless of baseline iron repletion status, C-reactive protein level, iron regimen

264 Vitamin D repletion stimulated appetite, normalized weight gain, a

265 ncy is common, it remains unclear which iron repletion strategy is associated with the lowest rate of

266 an indispensable amino acid and implement a repletion strategy.

267 Repletion studies in LBP KO mice using an LBP-adenoviral

268 ata are inadequate, an in-hospital depletion-repletion study was conducted.

269 We now report results of a depletion-repletion study with healthy young women hospitalized fo

270 ly in the presence nNOS inhibition (and cGMP repletion), suggests that multiple, redundant, and inter

271 ficiency is associated with obesity; whether repletion supports weight loss and changes obesity-relat

272 matory" monocyte subset responded to 25(OH)D repletion the most, demonstrating the greatest increase

273 eficiency and downregulated following folate repletion, the mechanistic basis for this relationship i

274 alyzed during mtDNA depletion and subsequent repletion to gain insight into the regulation of human m

275 Androgen repletion to mice bearing androgen-independent CWR22-R t

276 OXA2-deficient mouse model, coupled with LIF repletion to rescue the implantation defect, was used to

277 late evening activity are restored by NAD(+) repletion to youthful levels with NR.

278 Although results of intravenous iron repletion trials have been promising, regularly treating

279 line adjustment (9 d), depletion (27 d), and repletion (two 21-d and then one 14-d) periods.

280 NAD(+) repletion via nicotinamide riboside ameliorated disease

281 Liver glycogen repletion was also brisk throughout the study period, re

282 The beneficial effect of NAD repletion was seen, however, only when Sir2alpha was int

283 Using neutrophil depletion and repletion, we found that neutrophils are the predominant

284 ed at baseline, end of depletion, and end of repletion, were used for targeted and nontargeted metabo

285 extrin and fructose) enhances liver glycogen repletion when compared with maltodextrin alone.

286 ose tissue in response to feeding and energy repletion, while leptin decreases food intake.

287 whether doing so is safe and whether NAD(+) repletion will have beneficial effects in ageing humans.

288 choline-deficient diet for up to 42 d before repletion with 138-550 mg choline/d.

289 ty from NHS, and activity can be restored by repletion with anti-Galalpha1-3Gal affinity-purified Abs

290 However, repletion with autoreactive B cells may explain the rela

291 Cholesterol depletion and repletion with methyl-beta-cyclodextrin reversibly alter

292 Repletion with PGE(2) analogs restored homeostasis, and

293 Moreover, the responses were restored upon repletion with PMN obtained from WT mice but not with PM

294 -2 receptor antagonist but was restored upon repletion with purified monocytes.

295 significantly increased E16 inclusion, while repletion with recombinant hnRNP A/B restored E16 silenc

296 es of beta-carotene and vitamin A, depletion-repletion with vitamin A and beta-carotene supplements,

297 onically undernourished population, maternal repletion with vitamin A at recommended dietary levels b

298 Repletion with zinc restored cell growth and reversed DN

299 on and hypothesized that selective substrate repletion would restore mitochondrial metabolic function

300 e tested the hypothesis that dietary glycine repletion would reverse endothelial dysfunction in prote