ライフサイエンスコーパス: replicate

1 r oligonucleotides, which would be easier to replicate.

2 ngulate and prefrontal regions did not fully replicate.

3 ch sample against each CRISPR RNA (crRNA) in replicate.

4 s are small and the results are difficult to replicate.

5 nse to exercise, respectively, were formally replicated.

6 performed in bronchial epithelial cells and replicated.

7 S were small, and the GWAS findings were not replicated.

8 s only when the space-for-time assumption is replicated.

9 ed as a new form of advanced AMD, and herein replicated.

10 croenvironment in which the virus population replicates.

11 sing covariance among time points and across replicates.

12 proach, using sites as spatially independent replicates.

13 riptional changes across multiple donors and replicates.

14 bust assessments across xenograft biological replicates.

15 mental variations among biological/technical replicates.

16 ccounts for variability between experimental replicates.

17 ch results in missing identifications across replicates.

18 t changed consistently across the biological replicates.

19 genome might be similar across experimental replicates.

20 intra-day assays, respectively by using five replicates.

21 hat persisters are small at birth and slowly replicating.

22 ing that 32% of this population was actively replicating.

23 We identified and replicated 10 cerebrospinal fluid proteins including IL-

24 We further replicated 50 genes in an independent GWAS, including on

25 ICC was largest for the statistically equal replicates (70%-91% for FBN; 90%-96% for FBW discretizat

26 We further discover and replicate a potential causal mechanism behind this inter

27 Vertebrate genomes replicate according to a precise temporal program strong

28 ct of HCMV serostatus but not diagnosis that replicated across samples.

29 their precision in superior frontal cortex (replicated across studies, combined n = 133), which was

30 ent and crisis episodes in mental healthcare replicated across two services.

31 ware that will not only condense output from replicated ADMIXTURE runs, but also infer from these dat

32 HARGE and SpiroMeta consortia showed that 16 replicated after Bonferroni correction and another 12 re

33 ithin infected cells.IMPORTANCE Many viruses replicate almost entirely in the cytoplasm of infected c

34 plant-pollinator community by transplanting replicated alpine meadow turfs downslope along an elevat

35 This effect was reduced for the elderly, replicating an earlier finding.

36 and reproducibility is demonstrated between replicate analyses on the same derivatized SPME fiber an

37 Our work enables others to replicate and extend our results with waveforms from any

38 Overall, our results replicate and extend prior observations that the renin-a

39 rom invading viruses that depend on dNTPs to replicate and is frequently mutated in cancers and Aicar

40 ense strategy that pathogenic viruses use to replicate and propagate in their host.

41 ncentrations exhibited high variance between replicates and a strong negative trend in the large (>=5

42 h comparison with previous data, independent replicates and both inversion breakpoints, we demonstrat

43 This study replicates and extends the previously observed decrement

44 ing similarity between the signatures of bio-replicates and the drugs with shared targets, and the re

45 codes an RNA-dependent RNA polymerase, which replicates and transcribes the vRNA genome.

46 s critical for life, including transcribing, replicating and repairing DNA.

47 all six passages, whereas ME7 prions did not replicate, and RML prions replicated only very weakly af

48 applicable to any dose-response data without replicates, and improves biomarker discovery for precisi

49 equencing coverage and numbers of biological replicates, and we show that the use of additional biolo

50 or data points exceeds the number of genuine replicates, and when the statistical analysis treats all

51 CP1, excising from the bacterial chromosome, replicating, and mobilizing to new host cells following

52 uccessfully used in photonics, it has yet to replicate any of these complex naturally occurring struc

53 Using a simple and easily replicated approach, Bladon et al. (2020) were able to q

54 Replicates are run on six mass spectrometers operating c

55 e models, have expanded our opportunities to replicate aspects of human allotransplantation and to as

56 el parameters are identifiable with only one replicated assignment per sample and that accuracy and p

57 imates 63 and 42%, respectively, using three replicated assignments (e.g., PCRs for microsatellites)

58 are relatively insensitive to the number of replicated assignments for high-quality samples.

59 We replicated associations for two VEO-IBD genes, ADAM17 an

60 539157 in PJA1, and rs12616219 near TMEM182) replicated at a Bonferroni significance threshold (P < 4

61 (P=6.65x10(-6) for the interaction test) and replicated at nominal significance level (P=0.013) in SM

62 d after Bonferroni correction and another 12 replicated at nominal significance level.

63 ilarities between septic humans and mice are replicated at the circulating blood leukocyte transcript

64 chemical stimuli, they are among the fasting replicating bacteria studied, capable of responding almo

65 gnal-detection-theory-based model accurately replicated behavioral outcomes and indicated that the de

66 he empirical foundations for prospect theory replicate beyond any reasonable thresholds.

67 patterning (BIOMAP) is a versatile method to replicate biological features either as positive or nega

68 important viral protein that makes the virus replicate by binding to its DNA and turning on the expre

69 Prions (PrP(Sc)) replicate by inducing a normal cellular prion protein (P

70 The survival results may be replicated by adopting key treatment decisions, such as

71 This finding was replicated by analysis of HLA serotypes in 338 individua

72 RIIIJ effects were replicated by application of the K(v)1.1 selective antag

73 These SLE-associated changes could be replicated by IFN treatment of keratinocytes.

74 ailure to habituate to acoustic stimuli, are replicated by short-term treatment with the NMDAR antago

75 sin was as a ring that encircled and cohered replicated chromosomes until its cleavage triggered the

76 determine how they topologically interact in replicated chromosomes.

77 ssion of STS PC1 proteins was confirmed in a replicate cohort of adult AD patients with FA to peanut,

78 Here, we use controlled, replicated communities of two Tribolium species (T. cast

79 By biochemically replicating conditions necessary for antibiotic protecti

80 The assay shows excellent replicate consistency with 8% intra- and 12% interday co

81 non-treated cells possess uracil in the late replicating constitutive heterochromatic regions, while

82 Here, we generated replicate controls and reanalyzed published MeRIP-seq da

83 found in plasma were also found in DBS, and replicate DBS genotyping revealed that a single test det

84 e show that the use of additional biological replicates decreases variance in estimates of effect siz

85 tin and proximity ligation assays with newly replicated DNA revealed the binding of ATAD2, a bromodom

86 le hub that traverses the macronucleus while replicating DNA.

87 ent maturation, replication of 'difficult-to-replicate' DNA regions, end resection, stalled replicati

88 Exposing replicated Drosophila populations to a novel temperature

89 on fragile sites and telomeres, remain under-replicated during interphase and subsequently complete l

90 the bias of the former towards regions that replicate early and the skew of the latter towards regio

91 Of concern, rSADS-CoV also replicated efficiently in several different primary huma

92 utilizing multifunctional RNA polymerases to replicate entire viral genomes and transcribe viral mRNA

93 To this end, we report a self-replicating Epstein-Barr virus-based episomal vector for

94 monstrated the quality of the MVP dataset by replicating established genetic associations with height

95 MCM complexes accumulated within both early-replicating euchromatin and telomeric heterochromatin, a

96 ponses to reward, the pattern of results was replicated even when patients with impulse control disor

97 We find that these uniquely replicated evolutionary events support the idea that co-

98 The model replicates experimental observations that indicate that

99 were preserved for the different OvC types, replicating features of the original tumour and compatib

100 s (six newer and four older) were grown in a replicated field trial.

101 in T cells, monocytes, and whole blood that replicated findings from a past methylation study of MDD

102 Our replicated findings illuminate the computations by which

103 CC resides at a fixed location at the OP and replicates first.

104 edian removal percentage of 92% among the 10 replicate foaming experiments.

105 discuss which aspect of human HF each model replicates, focusing on whether HFpEF or HFrEF is induce

106 o the renin-angiotensin system as it did not replicate for beta-blockers, calcium channel blockers, o

107 used clades as phylogenetically independent replicates for pattern analysis, but a few recent studie

108 This implies that the virus had not been replicating for multiple years prior to its re-emergence

109 can be used as a safe agent (as they cannot replicate) for bacterial therapy.

110 to reach a cPRA <98% was within 1 titer for replicates from the same sample, with 90% (36/40) concor

111 human cancers, and FOXO3 is the second most replicated gene associated with extreme human longevity.

112 Whereas ATP1A3 is a replicated gene in rare neuropediatric diseases, this ge

113 ies with male C57BL/6 mice that persistently replicate HBV (genotype D, serotype ayw)-either from a t

114 '715/4'640 (80%) MSM and identified 177 with replicating HCV infections (4.8%); 150 (85%) of which st

115 uating the reproducibility of StatDns across replicate Hi-C data sets, we use this implied StatDn - k

116 structures mean that mice do not adequately replicate human complement regulators, including CR1 and

117 However, replicating human-made decisions may inherently be biase

118 -induced hypoglycemia and glucoprivation and replicated hypoglycemia-associated autonomic failure.

119 s (reoviruses) are nonenveloped viruses that replicate in cytoplasmic membranous organelles called vi

120 r data suggest that NiV does not efficiently replicate in EFBs in vivo.

121 m a pig in the agricultural fair outbreak to replicate in ferrets and transmit from swine to ferret.

122 o kill Galleria mellonella larvae, could not replicate in G. mellonella hemolymph, and also had a gro

123 ur months of life, identifiable viruses that replicate in human cells become more prominent.

124 ses to evade the host innate response and to replicate in macrophages.

125 n Bangladesh have the capacity to infect and replicate in mammals, they show very limited capacity fo

126 Using the ability of T7 phage to replicate in nitrogen-starved bacteria as a biological p

127 nmental conditions, which are challenging to replicate in the laboratory.

128 me conditions, SARS-CoV-2 virus is unable to replicate in these mosquitoes and therefore cannot be tr

129 itiation regions (IRs), the first regions to replicate in very early S phase.

130 l oncolytic VSVs with an improved ability to replicate in virus-resistant PDAC cell lines.

131 e ordered protein assemblies that faithfully replicate in vivo and cause specific biological effects.

132 of African ancestry, which was successfully replicated in 1,645 survivors of European ancestry but w

133 GP2 gene variants and pancreatic cancer are replicated in 10,822 additional cases and controls of Ea

134 Findings from the Rotterdam study were replicated in 186 AD patients of the BioFINDER study.

135 the sediment-water interface that were well replicated in 1D profiles and 2D images.

136 These findings were replicated in 2.3 million Danes.

137 Findings were replicated in 616 samples from Mexico and Colombia.

138 ly detected at TTS, which are preferentially replicated in a head-on orientation relative to the dire

139 er it is unclear whether this finding can be replicated in a large number of subjects.

140 e as a clinical screening tool for BECTS, if replicated in a larger study population.

141 08845-by-fenofibrate interaction on MACE was replicated in African Americans from ACCORD (N = 585, P

142 This behavior was then replicated in an application to real RNA-Seq data where

143 cerol, C36:1 phosphatidylcholine and sucrose replicated in an independent dataset of 980 participants

144 These observations were replicated in an independent group dataset of 120 indivi

145 The associations for 10 of these loci were replicated in an independent sample of 16,787 cases and

146 rajectory groups and remission patterns were replicated in an independent sample.

147 ed with increased p53 mediated apoptosis was replicated in bronchial biopsies of COPD patients.

148 idate markers of disease activity need to be replicated in independent datasets and, if validated, ma

149 1 isolates that were tested, 10 infected and replicated in mice without prior adaptation.

150 Key findings were replicated in narrow/clear cells in the epididymis, also

151 either is it clear if trial findings will be replicated in routine clinical practice at scale.

152 d in the discovery phase, most of which were replicated in SHIP-2.

153 rated, as waking experiences are never truly replicated in sleep but rather appear in very altered or

154 Framingham Heart Study (FHS, N = 6,004), and replicated in the Kansas City Osteoporosis Study (KCOS,

155 HS sample, and the lead SNP was successfully replicated in the KCOS sample (one-sided P = 0.04).

156 redators (apex predators) in field mesocosms replicated in the leaf-litter community of Iberian beech

157 ine mammary infection model, P. zopfii GT-II replicated in the mammary gland and caused severe inflam

158 These Htt/HTT associations were replicated in the Q175 Htt knock-in mouse model (p = 6.0

159 uced and preserved ejection fraction and was replicated in the Washington University cohort and a coh

160 This association was replicated in two independent samples of SJLIFE survivor

161 -scale pharmaceuticals and living systems in replicated in vivo conditions, the continuing developmen

162 Human disease features are replicated in X. tropicalis larvae with morpholino knock

163 plex in the South Asian dataset that clearly replicates in the Europeans (rs201026476; combined odds

164 hat infection with a virus that persistently replicates in the intestinal mucosa increases epithelial

165 resonance mass spectrometry considering six replicates in three different ionization modes (electros

166 terium that causes tularemia by invading and replicating in mammalian myeloid cells.

167 Despite replicating in the cytoplasm, ZIKV and Dengue virus (DEN

168 intervention in enough detail that it can be replicated, including context.

169 e 3 secretion system 2 (T3SS2) to invade and replicate inside host cells.

170 ligate intracellular bacterial pathogen that replicates inside the lysosome-derived Coxiella-containi

171 VI) are 98-102% and precision between sample replicates is better than 6.3%.

172 create "artificial muscles" in an attempt to replicate its versatility, seamless integration with sen

173 elial cells (LECs) infected with a lytically replicating KSHV BAC16 mutant.

174 landscape geneticists to utilize multiscale, replicated landscapes with both genetic diversity, and d

175 the skew of the latter towards regions that replicate late.

176 gion amplicon sequencing) communities across replicate lines over time, as well as a general loss of

177 While some IBV strains replicate locally, others can disseminate to various org

178 SPME fiber device for up to three technical replicate measurements of one sampling event.

179 Replicate measurements within a given device consistentl

180 ed mostly by the random fluctuations between replicate measurements, and it was possible to detect mo

181 y using the Virtual Chinrest we can reliably replicate measures of visual crowding, which depends on

182 first whole-ecosystem experiments to involve replicated metagenomic assessment.

183 e related reports of chemically fuelled self-replicating micelles, our vesicular system was too stabl

184 coding mutations associated with obesity, we replicated midbrain cell types from the anterior pretect

185 opted an endoreplication in which the genome replicates, mitosis is omitted, and cells grow in size.

186 We use a spatially replicated, multiyear experiment in four agricultural se

187 proved to be a suitable and fast method for replicating nasal cavity structures and for the experime

188 It is unknown to what extent such approaches replicate natural/endogenous orexin signals, which rapid

189 talized Arabidopsis cell suspensions to sort replicating nuclei and determine genome-wide cytosine me

190 E51 rendered M. tuberculosis cells unable to replicate on propionamide, glucose, or glycerol.

191 ME7 prions did not replicate, and RML prions replicated only very weakly after five passages.

192 DNA synthesis, which allows for labeling of replicating or repaired DNA.

193 rd-Trondelag Health Study and UK Biobank and replicated our findings using 222,368 siblings from 23an

194 In out-of-sample tests on manually replicated papers from diverse disciplines and methods,

195 experimentally manipulated in order to: (1) replicate past studies suggesting that a group of viewer

196 , CAPG 10, 100, 1000 ng/mL: n = 3 biological replicates per treatment per species).

197 es in the TME and highlight a need to better replicate physiologic conditions to select targets, clar

198 printed stem cells present an opportunity to replicate physiological microenvironments with precision

199 However, differential methylation of two replicated PIK3CD (phosphatidylinositol-4,5-bisphosphate

200 re, we (co)evolved five microbial species in replicate polycultures and monocultures and quantified l

201 vioral, and fitness-related traits from each replicate population periodically, and sequenced genomic

202 e test between these opposing theories using replicate populations of the model insect Tribolium cast

203 hanges in the transcriptome of synchronously replicating populations of Mycobacterium tuberculosis (M

204 Nevertheless, there are several replicated positive findings in BD, including decreased

205 istones dilute H3K27me3 by 50% each time DNA replicates, PRC2-deficient ISCs initially retain suffici

206 ask compared to a storytelling game, thereby replicating previous studies testing Western populations

207 Replicating prior work, sustained effects associated wit

208 sis of prevalent type 2 diabetes revealed 24 replicated proteins, of which 8 are novel.

209 been mostly studied using mechanistic models replicating qualitative features of group behavior, and

210 Replicate reactors treating domestic wastewater were ope

211 onal recovery and resilience can vary across replicate reactors, and that nitrification recovery need

212 t associations were detected between rCBF in replicated regions and clinical measures of MDD chronici

213 our types and patients, are enriched in late-replicating regions and correlate with inversions.

214 C5/6 leads to DNA replication stress at late-replicating regions such as pericentromeric heterochroma

215 Using a replicated regression approach, we imposed single deluge

216 Representative strains of three HA subgroups replicated restrictively in specific-pathogen-free chick

217 Applying PAIRADISE to replicate RNA-seq data of a single individual and to pop

218 We show that across replicate sampling transects of two pairs of barn swallo

219 Here, we inoculated replicated, sand-packed, continuous mesocosms with groun

220 Suicide Data for the United States (MSD-US) replicate several individual and contextual findings, co

221 Rainbow-KSHV replicated similarly to a prototype reporter-KSHV, KSHVr

222 els revealed that while the SFTSV-A46 mutant replicated similarly to wild-type SFTSV (SFTSV-WT), it s

223 S-CoV-2-Nluc) that is genetically stable and replicates similarly to the wild-type virus in cell cult

224 DSB repair occurs as replicated sister chromatids are connected to a polymeri

225 We performed additional analyses on 21 replicated sites in 785 case patients and 2124 controls

226 cate strategy (9x) and a concentrated single-replicate strategy in which 5 ml of plasma is concentrat

227 to identify the sources of variation between replicate studies and study designs that produce robust

228 , saliva with 5% human serum was optimal for replicating subgingival microbiomes from health and dise

229 hat pol eta is not responsible for correctly replicating T-containing pyrimidine dimers, a phenomenon

230 These decisions are easier to replicate than technical skills or system factors.

231 e restricted to GABAergic cell types largely replicate the behavioral phenotypes associated with mous

232 We replicate the benefits of the intervention in a second s

233 farms, random forest algorithms were able to replicate the complex herd level diagnoses made by speci

234 he multi-batch design, we reduce the need to replicate the experiment, which can reduce the total num

235 While we replicate the occurrence and modulation of beta-bursts a

236 and its ligand kisspeptin, Kiss1 (Kiss1-/-) replicate the phenotype of isolated hypogonadotropic hyp

237 However, we failed to replicate the results and did not observe glutamate, d-(

238 These results may not replicate the typical clinical situation and are signifi

239 dware toward future intelligent systems that replicate the vast capabilities of biological organisms.

240 L in additional 524 unrelated TS samples and replicated the association (P value = 0.001).

241 om the Million Veteran Program independently replicated the association of smoking behavior with CAD

242 The model replicated the Ca(2+) spike morphology and its critical

243 ndent study on 24 individuals with HVDAS and replicated the existence of the two mutation-dependent e

244 In experiment 3, we replicated the finding of intact context discrimination

245 ne experiment with 1153 participants further replicated the findings of prior laboratory work, demons

246 re in human airway epithelial (HAE) cultures replicated the in vivo antiviral host response 7 days po

247 In this study, we first replicated the standard and joint Simon effects in adole

248 an independent series of diagnostic biopsies replicated the subgroups, with immune cell composition c

249 ht beam to produce an electronic torque that replicates the effect of strain created by high pressure

250 he proliferating cell nuclear antigen (PCNA) replicates the lagging strand and cooperates with flap e

251 structural basis of Pol delta's activity in replicating the human genome.

252 roles in ensuring that eukaryotes accurately replicate their genomes.

253 ked to novel strategies the parasites use to replicate their unconventional genomes.

254 Further research is needed to replicate these findings and assess long-term outcomes.

255 We can also replicate these IBD microbial co-abundances in longitudi

256 We replicate these newer findings in the Hadza of Northern

257 We replicated these findings in 1898 individuals in the Fra

258 Study 2 replicated these findings with a nationally representati

259 is experience, we also provide a roadmap for replicating these projects in other low-resource setting

260 If replicated, these findings could provide new insights in

261 Here, we attempted to replicate this finding in primary cultured spinal cord n

262 However, in this project, we failed to replicate this result.

263 We replicated this finding in an independent cohort and fou

264 sample Mendelian randomization (MR) and then replicated this investigation in the SpiroMeta Consortiu

265 We replicated this result in two healthy datasets and in pa

266 t mild potentials, along with guidelines for replicating this strategy in synthetic systems.

267 n magnetic resonance imaging tractography to replicate those connections in nonhuman primates, before

268 priori hypotheses, these exploratory results replicate those of a recently published study documentin

269 These findings replicate those of phase 1b study, and warrant further e

270 urements and Main Results: We identified and replicated three new genome-wide significant (P < 5 x 10

271 (0, 168, 336, and 672 kg N/ha) were used and replicated three times.

272 We conducted a primary and replicated time-series analysis of retrospectively colle

273 to the draining lymph node (dLN) where they replicate to large numbers.

274 leading non-regulatory institutions) can be replicated to address other identified gaps in the analy

275 Gamma-clade viruses replicated to higher levels in mammalian cells than pand

276 del of a specific psychiatry disorder may be replicated to study other complex diseases.

277 the bloodstream to the gallbladder, where it replicates to extremely high numbers.

278 Early after inhalation, Yersinia pestis replicates to high numbers in the airways in the absence

279 We use 177 unique pairs of genetic replicates to identify factors that affect variant call

280 ins of the helicase directly in front of the replicating-transcribing holo-RdRp, constraining models

281 s us to infer expression state of genes from replicate transcriptomic libraries.

282 h model is evaluated based on its ability to replicate two hallmarks of bistability during auditory s

283 nt (ZP Klentaq) contribute to its ability to replicate UBPs with improved efficiency compared with Kl

284 Replicate (urban) samples indicate that the Na(2)CO(3) s

285 The cabin was replicated using a custom-made pressure chamber.

286 tion, the framework confined environment was replicated using a molecular cage, Pd(6)(TPT)(4) (TPT =

287 way basal stem/progenitor cells; this can be replicated using LAE and SAE immortalized basal cell lin

288 One of the replicated variants, rs178252, is located in an open chr

289 ance of fuel-driven, out-of-equilibrium self-replicating vesicles.

290 to overcome this restriction and efficiently replicate viral RNA in the presence of human ANP32 prote

291 associates with HSV-1 replication forks and replicating viral DNA, suggesting that it may play a dir

292 differentiation of actual IAV infection with replicating virus versus individuals exposed to high lev

293 By comparing both designs across independent replicates, we could indeed show that the use of such a

294 Here, we have used a highly biologically replicated whole transcriptome sequencing approach to id

295 texts reveals that DNA containing the UBP is replicated with an efficiency and fidelity similar to th

296 and in an intergenic region on chromosome 2 replicated with the same direction of effect in the seco

297 tween rs8192575 and smoking is significantly replicated with two additional data (P(INT) = 0.0454, 0.

298 inding domain of sigma1 yielded a virus that replicates with faster kinetics than the parental virus

299 Twelve of 13 theoretical contrasts replicated, with 100% replication in some countries.

300 coronavirus 2 has the potential to directly replicate within cardiomyocytes and pericytes, leading t