ライフサイエンスコーパス: replication study

1 eplicated findings in an independent sample (replication study).

2 with the risk of clinical CAD in this large replication study.

3 all 12 SNPs were confirmed in an independent replication study.

4 consideration to whether it is a de novo or replication study.

5 risons between NC1 and the autism group as a replication study.

6 en (mean [SD] age, 25.4 [6.0] months) in the replication study.

7 hese associations were also significant in a replication study.

8 ucoma patients in a second sample used for a replication study.

9 a meta-analysis with a published GWAS and a replication study.

10 spectively) but not to cephalosporins in the replication study.

11 ant predictor of the P-value in a subsequent replication study.

12 hese experiments will then be published in a Replication Study.

13 identify SNPs that can be pursued in future replication studies.

14 covery studies and 32 277 individuals from 6 replication studies.

15 y identified, and 5 SNPs were later found in replication studies.

16 Two additional cohorts were used for replication studies.

17 the initial GWAS were not associated in the replication studies.

18 tiology of NHL, and should be prioritized in replication studies.

19 that variant and facilitate the planning of replication studies.

20 esting additional variants is commonplace in replication studies.

21 novel risk loci that require confirmation by replication studies.

22 ary in the absence of converging evidence or replication studies.

23 peline as open-source software to facilitate replication studies.

24 irus (CCMV) is a widely used model for virus replication studies.

25 ocumentation of indications would facilitate replication studies.

26 t their institution valued new research over replication studies.

27 The UK Biobank dataset was used for the replication studies.

28 fect estimates from the GIANT consortium and replication studies.

29 showed evidence of trans-association in two replication studies.

30 DCYAP1R1 were genotyped in our study and six replication studies.

31 diseases, often with inconsistent results in replication studies.

32 mbined meta-analysis of all 22 discovery and replication studies.

33 ditors publishing in their own journals, and replication studies.

34 associated overall and in 3 of 5 individual replication studies.

35 (cases) and 3,182 controls), an independent replication study (1,440 cases and 1,316 controls) and a

36 e each type's heterogeneity from 70 multilab replication studies, 11 prospective meta-analyses of stu

37 iginal study: 44 total (20 PTSD); conceptual replication study: 40 total (20 PTSD)) underwent threat

38 Analyses of three replication studies: a cohort of individuals diagnosed w

39 N22 (discovery-study allelic P=6.6 x 10(-4); replication-study allelic P=5.6 x 10(-8)), which encodes

40 Additional virus replication studies also revealed that the Vif protein o

41 Larger replication studies among nulliparous women are needed t

42 type 1a replicons should be useful for basic replication studies and for antiviral development.

43 sis for the design and interpretation of GWA replication studies and point to the importance of a cle

44 egrative summary, we review various types of replication studies and then discuss the most commonly v

45 Replication studies and understanding the roles of these

46 such two-stage data is to view stage 2 as a replication study and focus on findings that reach stati

47 rried out a genome-wide association scan and replication study and found an association between SLE a

48 ociated with ovarian cancer risk both in the replication study and in combined analyses.

49 This finding was confirmed in each replication study and overall meta-analysis (OR=1.24, 95

50 t GTF2I by heterogeneity mapping followed by replication studies, and pinpointed a possible causal va

51 from China and 2 from the United States) for replication studies, and we identified heterozygous MGA

52 he presence of real effects in a low-powered replication study, and instances of such association inc

53 lation controls; performed follow-up genetic replication studies; and, conducted in silico and in vit

54 al white populations were used for follow-up replication studies: another independent cohort of CAD-

55 Replication studies are clearly warranted, as such child

56 Replication studies are critical to investigation of com

57 A number of large-scale replication studies are currently trying to identify the

58 While replication studies are necessary, these findings may in

59 Replication studies are needed for several other importa

60 Replication studies are needed to confirm our findings.

61 Ultimately, larger replication studies are needed to confirm the identified

62 Future replication studies are needed to confirm these associat

63 Additional replication studies are needed to identify more stable a

64 Replication studies are needed to validate these results

65 While replication studies are needed, these findings should en

66 Replication studies are required to confirm or refute th

67 Future independent replication studies are required to confirm these findin

68 only tentative evidence of association, and replication studies are required to establish their vali

69 ty to diabetic retinopathy; however, further replication studies are required to validate these assoc

70 FSH as a reliable imaging biomarker, further replication studies are required.

71 Because large replication studies are sorely needed, we recruited over

72 s drug markers may not be inconsequential in replication studies, as is generally assumed.

73 In vitro CIRV replication studies based on isolated mitochondrial prep

74 In vitro CIRV replication studies based on isolated mitochondrial prep

75 atio of sample sizes between the initial and replication studies, but not on the underlying effect si

76 Replication studied by single DNA molecule analyses and

77 A combined analysis of the initial and replication studies by logistic regression showed CFLD t

78 Overall, our results suggest that replication studies can contribute to self-correction wi

79 In the replication study, CFLD was associated with the SERPINA1

80 s) and followed up three lead signals in six replication studies (combined N = 19,089).

81 ents and 866 healthy controls, followed by a replication study comprising 658 patients with invasive

82 Replication studies confirmed IL23R associations in inde

83 The replication study confirmed the association of the TGFbe

84 This is the first replication study confirming the effectiveness of a heal

85 case-control data can improve the design of replication studies considerably.

86 alysis of primary results was performed with replication studies containing 12 174 heavy and 11 290 l

87 Because the FISH replication studies could not directly distinguish betwe

88 Specifically, all five "replication" studies define a positively associated hapl

89 , we report the results of a discovery and a replication study, each involving a double-blind, placeb

90 This replication study evaluates the relationship between sea

91 tients and 400 controls from the U.S. and in replication studies for 308 POAG patients and 178 contro

92 covalently bonded, and carried out in vitro replication studies for the lesion-bearing substrate wit

93 Replication studies from several populations showed conf

94 op prediction intervals for the P-value in a replication study given the P-value observed in an initi

95 In the CABS replication study, Gln27 homozygous participants similar

96 We performed association and replication studies guided by a priori linkage findings

97 Association replication studies have a poor track record and, even w

98 e association studies (GWAS) and large-scale replication studies have identified common variants in 7

99 Recent genome scans and replication studies have identified replicated linkage b

100 Several replication studies have reported confirmation of an ass

101 ificant results in both the original and the replication study have been interpreted as a 'replicatio

102 Meta-analysis of the discovery and replication studies identified one novel locus 6p22.1 (P

103 Replication studies identified two further patients with

104 This extended replication study identified 2 additional asthma risk lo

105 Meta-analysis of the discovery and replication studies improved the association signal (p =

106 In independent replication studies in 16,373 women, each major allele w

107 in the Pune Maternal Nutrition Study (PMNS), replication studies in 3418 individuals from other India

108 which was followed by in silico and de novo replication studies in 37,691 and 17,642 additional east

109 enetic ancestry and ethnicity, and performed replication studies in an additional 531 Latinos.

110 We perform replication studies in an independent meta-analysis of c

111 n mapping was followed up by association and replication studies in an independent sample.

112 PMBB with WES linked to EHR phenotypes, with replication studies in BioVU, UK Biobank, MyCode, and DC

113 Replication studies in human cohorts with fetal alcohol

114 Replication studies in other populations should be a pri

115 a useful asset for synthetic biology and DNA-replication studies in particular.

116 -wide genotyping of the European cohorts and replication studies in the Japanese cohort identified co

117 thnically matched controls, and we performed replication studies in two independent European cohorts.

118 We did replication studies in two independent populations consi

119 An independent replication study in 16 novel subjects confirmed these n

120 We performed a replication study in 175 trios consisting of probands wi

121 432,028 controls of European ancestry and a replication study in 3989 cases and 226,643 controls pro

122 subsequent transmission disequilibrium test replication study in an independent cohort confirmed the

123 We then conducted a replication study in an independent cohort of men from t

124 A replication study in an independent sample from the Fram

125 69 individuals to 293,723 individuals, and a replication study in an independent sample of 111,349 in

126 Here we report an NVC QTL replication study in an independent sample of 213 AGRE f

127 A replication study in an independent set of Mexican Ameri

128 A replication study in Chinese (3,043 cases and 5,074 cont

129 osis household contact study in France and a replication study in families from South Africa to confi

130 Replication study in GenNet confirmed the association of

131 Here we conducted a GWAS and a replication study in Koreans using a total of 1,085 DTC

132 Using a genome-wide association and replication study in up to 100,000 individuals, we ident

133 sychedelic drug research that merit rigorous replication studies include 3,4-Methylenedioxymethamphet

134 of lipid levels in 8344 subjects followed by replication studies including 14 739 additional individu

135 hypertension in 11 816 subjects followed by replication studies including 69 146 additional individu

136 e rankings were followed up in a three-stage replication study including 4,064 cases and 4,685 contro

137 l associations that can be pursued in future replication studies, including an intergenic SNP, rs4761

138 ed progress, including a lack of large-scale replication studies, inconsistencies in defining valid t

139 Transfection and replication studies indicated that c-Jun and c-Fos can s

140 I review numerous replication studies indicating that AMT data is reliable

141 ical evidence from two large-scale multisite replication studies indicating that covariate shift can

142 The Replication Study involved 34 MDD subjects, and yielded

143 Replication studies involving additional persons with co

144 Replication studies involving larger population samples

145 s further delineated in: (1) a pooling-based replication study involving an additional 500 AN patient

146 orts (n = 13,813) followed by two additional replication studies (n = 2,267) including approximately

147 orts) and followed up two lead signals in 13 replication studies (n = 27,591).

148 verall meta-analysis combining discovery and replication studies (n = 51,258).

149 t a genome-wide association (n = 17,967) and replication study (n = 13,615) to identify genetic loci

150 In the replication study (n = 245), we confirmed four VOCs of i

151 of previous studies, n = 450; pre-registered replication study, n = 807), we investigated how depress

152 In the replication study, no evidence was observed for hypometh

153 Replication study observed significant association signa

154 from 11 studies and followed up 6 SNPs in 3 replication studies of 2,198 cases and 4,918 controls.

155 We also carried out in vitro replication studies of a substrate containing a site-spe

156 In replication studies of methylation in other tissues, mos

157 In vitro replication studies of Pol iota show that it replicates

158 ction: Genetics and Environment, followed by replication studies of prioritized single nucleotide pol

159 whose bypass adheres to the "A-rule." Recent replication studies of the oxidized abasic lesion, 2-deo

160 ce analysis of HLA-DRB3 exon 2 in a targeted replication study of 281 informative T1D family members

161 lipoprotein(a) level measurements, and in a replication study of 379 patients with echocardiography-

162 In a large case-control replication study of 438 patients with SLE and 219 contr

163 A candidate gene replication study of association between refraction and

164 a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up

165 Finally, our replication study of rs6435326, rs1053517 and rs1801318

166 A full replication study of the GABA(B) modulator reinforces th

167 x GeneChip Human 20k cSNP Kit, followed by a replication study of the more promising results.

168 asthma risk loci by performing an extensive replication study of the results from the EVE Consortium

169 phenotype data, biobanks can also facilitate replication studies on a phenome-wide scale.

170 We further carried out in vitro replication studies on a substrate containing a site-spe

171 enes on metabolic outcomes; however, further replication studies on large samples are needed to confi

172 further genotyped this SNP in two subsequent replication studies (one with 3,750 women and the other

173 e association study (P < 5 x 10(-8)) and the replication studies (P < .05), including a missense vari

174 n the initial study (P = 0.0052), and in the replication studies (P = 0.032).

175 Replication studies play an essential role in corroborat

176 rther using other statistical methods and in replication study populations.

177 indings from genome-wide association through replication studies, preferably using multi-omic dataset

178 scoping review to identify English language replication studies published between 2018 and 2019 in e

179 Replication experiments were completed and Replication Studies reporting the results were submitted

180 e 56% and 45% for the initial and subsequent replication studies, respectively.

181 Replication studies revealed that a group of interviral

182 In vitro and in vivo replication studies revealed that FodU can be mutagenic.

183 Furthermore, an independent replication study sample of 837 cases and 968 controls f

184 Replication studies should integrate genomics and transc

185 Both replication studies showed an association of the rs66304

186 The replication study showed again that the autism group use

187 he three novel SNPs were followed-up in nine replication studies (Stage 2; N = 11 995), with rs905938

188 Data from this replication study suggest that Kraepelinian schizophreni

189 ss to raw data and protocols, the conduct of replication studies, systematic integration of evidence

190 Further replication studies targeting patients with advanced age

191 Our replication study tested 34 SNPs in 4,496 independent ca

192 e body of structural, biochemical, and virus replication studies that identify several inhibitors of

193 Third, we demonstrate by in vitro replication studies that several such hairpin i-motifs a

194 lly genotyped in an independent family-based replication study that, after quality control, consisted

195 In independent replication studies the 17q21 locus showed strong associ

196 s) of the four GWAS discovery scans and four replication studies, the 3p24.1 locus (rs6773363; MAF =

197 four original GWAS discovery scans and three replication studies, the 3q13.33 locus (rs9831894; minor

198 In the replication study, the area under the receiver operating

199 In the replication study, the chr3 associations were significan

200 In the replication study, the genetic variant rs10455872 also s

201 In the FINGEN replication study, the GRS explained 3.67% of TG respons

202 In the replication study, this single nucleotide polymorphism e

203 ing both reproducible research standards and replication studies to evaluate the fragility of study f

204 erestimation of the genetic effect may cause replication studies to fail because the necessary sample

205 e parafovea, emphasizing the contribution of replication studies to substantiate our knowledge about

206 Here we extended the in vitro replication studies to two replicative polymerases, exon

207 This replication study used a much larger patient cohort to e

208 formed genome-wide association Discovery and Replication Studies using cohorts of 2131 patients with

209 The replication studies using human polymerases hpolkappa an

210 In replication studies using similar methodology, many of t

211 rone activity measurements and in vivo HIV-1 replication studies using the same NC mutants.

212 We here performed a GWAS and replication study using a large Japanese cohort (9,906 c

213 wide association analysis and an independent replication study using a total of 1131 bladder cancer c

214 gammaRIIA and FcgammaRIIIA in a case-control replication study, using allele-specific polymerase chai

215 Replication studies verified the significant findings by

216 Lastly, a meta-analysis of the discovery and replication studies was performed.

217 A replication study was conducted in an independent, co-lo

218 nvestigations, a genome-wide association and replication study was conducted in two smoker cohorts to

219 A replication study was conducted using the SAGE sample wi

220 A replication study was performed in 240 nuclear Malian fa

221 A replication study was performed using data from the Gene

222 corded whether a registered protocol for the replication study was used, whether there was contact be

223 For the individual replication studies, we recorded whether a registered pr

224 In a replication study, we analyzed (11)C-Pittsburgh Compound

225 In this replication study, we examined the six top-most associat

226 In a replication study, we genotyped 10 single-nucleotide pol

227 In this replication study, we investigated the association betwe

228 In this replication study, we reassessed whether these genes are

229 For a replication study, we selected 10 SNPs in six chromosoma

230 The same DNAs that were used for replication studies were also assembled into duplex DNAs

231 Discovery and replication studies were conducted in specialty centers

232 Two replication studies were conducted to assess the associa

233 Replication studies were performed in 188 patients diagn

234 Replication studies were performed using 1541 subjects f

235 ntribute to the mutational outcome, in vitro replication studies were performed.

236 Replication studies were rare (n = 4), and only 16 studi

237 structural region are likely to affect viral replication, studies were performed to evaluate the effe

238 However, further replication studies will be required before any such ass

239 chology we illustrate that many original and replication studies with 'null results' are in fact inco

240 events, facilitating larger-scale and higher-replication studies with an expanded number of species.

241 TES effect, we performed detailed retroviral replication studies with an NSI/R5 (B-92BR021) and SI/X4

242 evated risk of lung cancer from the combined replication studies with an OR of 1.15 (95% CI, 1.04-1.5

243 idated by the results of multiple subsequent replication studies with stringent methods.

244 authors now present a randomized controlled replication study with baseline, postintervention, and 3

245 iral life cycle, we carried out a systematic replication study with entire genomes of human papilloma

246 xposure in conjunction with a-priori planned replication studies would reduce the number of false pos