ライフサイエンスコーパス: repopulation

1 ting inflammation, cell death and adipocytes repopulation.

2 bility of such scaffold to support stem cell repopulation.

3 loss enhanced hematopoietic stem cell (HSC) repopulation.

4 nfarct size, which is reversed by microglial repopulation.

5 subsequently needed to support cardiomyocyte repopulation.

6 ction to focus on detecting genes regulating repopulation.

7 antly increased proliferation and fibroblast repopulation.

8 proliferation resulting in incomplete T-cell repopulation.

9 helial carcinomas by abrogating early tumour repopulation.

10 tial drug targets for the promotion of liver repopulation.

11 ease paradoxically promotes neighbouring CSC repopulation.

12 re significantly depleted or increased after repopulation.

13 ent of the stage of pathology at the time of repopulation.

14 ich is able to support dental pulp stem cell repopulation.

15 itors throughout the CNS, resulting in rapid repopulation.

16 creas extracellular matrix to drive cellular repopulation.

17 and corresponded with the rate of host cell repopulation.

18 nsplanted cells and poses problems for liver repopulation.

19 st dual lineage contribution predominated in repopulation.

20 directly improves cell engraftment and liver repopulation.

21 particularly important for subsequent liver repopulation.

22 ng disease relapse or remission after B cell repopulation.

23 mia or inflammation, without improving liver repopulation.

24 through superior cell engraftment and liver repopulation.

25 cell engraftment and also kinetics of liver repopulation.

26 he potential to accelerate the rate of array repopulation.

27 ase in number, which may lead to accelerated repopulation.

28 apoptosis, alveolar regression and adipocyte repopulation.

29 etic stem cells and loss of competitive HSPC repopulation.

30 programmed epithelial cell death and stromal repopulation.

31 a also cleared with central endothelial cell repopulation.

32 HSCs display reduced capability of long-term repopulation.

33 tized microglia was prevented by elimination/repopulation.

34 rk available as a scaffold for cardiomyocyte repopulation.

35 es were unaffected by microglial elimination/repopulation.

36 f human HSCs capable of multilineage in vivo repopulation.

37 PLX5622 was discontinued to allow microglial repopulation.

38 elf-renewal capacity following depletion and repopulation.

39 icity and in some contexts can drive hepatic repopulation.

40 thdrawn 1-week later to allow for microglial repopulation.

41 abiosis mouse model of tissue disruption and repopulation.

42 ived factor(s) impaired senescent host liver repopulation.

43 by adopting methods aimed at reducing tumor repopulation.

44 ss, possess the capacity for extensive liver repopulation.

45 that growth hormone might promote host liver repopulation.

46 ew liver mass with extensive long-term liver repopulation (40.8 +/- 10.3%).

47 alveolar regression and absence of adipocyte repopulation 7 days post-weaning.

48 ed vital ECM proteins and was liable to cell repopulation, a crucial first step towards the generatio

49 anges are accompanied by increased long-term repopulation ability and expression of CD44 and CXCR4.

50 generated from RUNX1a EBs possess >/=9-week repopulation ability and show multilineage hematopoietic

51 of mitochondria and enhanced the competitive repopulation ability of primed HSCs by over 90-fold in v

52 ition of glycolysis enhanced the competitive repopulation ability of primed HSCs.

53 lly, elimination of Erf resulted in impaired repopulation ability, indicating that Erf is necessary f

54 dly decreased with impaired bone marrow (BM) repopulation ability.

55 -renewal capacity and long-term multilineage repopulation ability.

56 nature of corrected HSCs and showed that the repopulation advantage of these cells was not due to gen

57 oietic stem cell expansion and a competitive repopulation advantage, whereas homozygous deletion indu

58 SPCs engraft, and contribute to multilineage repopulation after autologous transplantation in a clini

59 cation, as well as the dynamics of phagocyte repopulation after full depletion.

60 creen to identify miRNAs that regulate liver repopulation after injury in live mice.

61 butes to the frequently observed accelerated repopulation after therapeutic irradiation.

62 to identify miRNAs that regulate hepatocyte repopulation after toxic liver injury using fumarylaceto

63 cities and show reduced but robust levels of repopulation after transfer.

64 f HSC quiescence, and failure of bone marrow repopulation after transplantation.

65 NFR1) was the most significant suppressor of repopulation among all of the genes tested.

66 Repopulation analysis after application of contact sensi

67 zed cells preferentially supported long-term repopulation and exhibited lymphoid-biased differentiati

68 sia after vascular injury via accelerated EC repopulation and growth.

69 SALL4 expanded HSCs/HPCs retain multilineage repopulation and long-term engraftment activities, which

70 xpressing macrophages and maintain long-term repopulation and multi-lineage differentiation potential

71 endogenous enzyme levels, maintain long-term repopulation and multi-lineage differentiation potential

72 ese factors as important regulators of liver repopulation and potential drug targets for the promotio

73 e animals, a preferential skewing toward CD4 repopulation and proliferation was observed, particularl

74 ult HSC function, negatively affecting their repopulation and self-renewal ability, partly through th

75 he long-term human graft, without perturbing repopulation and self-renewal of edited HSCs.

76 dHSCs to exit quiescence and abrogated their repopulation and self-renewal potential.

77 -negative cells, exhibit robust multilineage repopulation and serial reconstitution ability in immuno

78 able long-term reconstitution in competitive repopulation and serial transplantation experiments.

79 ntiation, while compromising their long-term repopulation and survival.

80 The mechanisms of T-cell repopulation and their posttransplantation kinetics are

81 loss, with rare clonal victors driving gland repopulation and tumor growth.

82 ment induced alternating mtDNA depletion and repopulation and was effective in shifting heteroplasmy

83 These findings suggest T-cell repopulation and/or immune reconstitution as putative me

84 e reversal with ART may be related to T-cell repopulation and/or immune reconstitution.

85 pletely rescued the impaired HSC quiescence, repopulation, and BM hematopoietic niche occupancy capac

86 erely defective in self-renewal, competitive repopulation, and bone marrow (BM) hematopoietic niche o

87 NG2(+) glial cell early proliferative, late repopulation, and distribution response after ablation i

88 ol size, impaired radioprotection, defective repopulation, and loss of quiescence.

89 In vivo functionality, host cell repopulation, and matrix remodeling of homologous transc

90 e long-term in vivo functionality, host cell repopulation, and remodeling of "off-the-shelf" tissue e

91 exposed to radiotherapy promoted rapid tumor repopulation, and this effect was suppressed by Hh inhib

92 We identified 17 regulators of HSPC repopulation: Arhgef5, Armcx1, Cadps2, Crispld1, Emcn, F

93 within their own attractor, thus driving the repopulation, as shown by fluorescent dye tracing.

94 Using this competitive repopulation assay, we compared the effects of INC424 (r

95 d directly to wild-type HSC in a competitive repopulation assay.

96 d repopulation potentials in the competitive repopulation assay.

97 In vivo competitive repopulation assays demonstrated a sevenfold difference

98 Competitive repopulation assays demonstrated disease appearance and

99 In competitive repopulation assays in vivo, they reconstituted the inna

100 e immune cells from bone marrow, competitive repopulation assays show that the intrinsic long-term fu

101 When challenged in competitive BM repopulation assays, primary human leukemia-initiating c

102 scence reporter mice in lineage tracking and repopulation assays, we show that CM expression cell aut

103 solated from nonleukemic mice in competitive repopulation assays.

104 ed mice as measured in long-term competitive repopulation assays.

105 logical effects in multi-lineage competitive repopulation assays.

106 rated successful in vivo detection of T cell repopulation at 2, 4, and 8 wk after HSC transplantation

107 Following BCDT and subsequent B cell repopulation, BAFF levels were significantly higher duri

108 Here, we characterized microglial repopulation both spatially and temporally following rem

109 of the sub-basal nerve plexus and keratocyte repopulation by 12 months postoperatively.

110 In LEC rats with liver repopulation by transplanted healthy hepatocytes, excret

111 Yet, efficient liver repopulation by transplanted hepatocytes is low in liver

112 wth hormone substitution might improve liver repopulation by transplanted hepatocytes, thus augmentin

113 The age-dependent liver repopulation by transplanted wild-type hepatocytes was i

114 This repopulation can be abrogated by a PGE2-neutralizing ant

115 recipient mice show maintenance of efficient repopulation capacities of Kit(int) but not of Kit(hi) L

116 increase in HSC numbers that show increased repopulation capacity and competitive advantage after tr

117 MSCs, HSCs expanded with rMSCs showed higher repopulation capacity and protected lethally irradiated

118 The impaired repopulation capacity extends to BCR-ABL(p210+) LSCs.

119 one ERDJ4 (also called DNAJB9) increases HSC repopulation capacity in xenograft assays, linking the U

120 cktail, the STFIA cocktail maintains in vivo repopulation capacity of cultured CD34+ cells.

121 iescence and improved the maintenance of the repopulation capacity of HSCs during aging.

122 or complex, severely impairs the competitive repopulation capacity of HSCs.

123 Moreover, loss of Ezh2 enhanced the repopulation capacity of Jak2V617F-expressing hematopoie

124 g antibodies, CD41+ HSCs possessed long-term repopulation capacity on serial transplantations and sho

125 colony forming HSCs, but also enhanced their repopulation capacity upon transplantation.

126 ber of HSCs and a complete loss of long-term repopulation capacity, whereas the stem cell compartment

127 damage accumulation in HSCs, and reduced HSC repopulation capacity.

128 ewal and nearly complete loss of competitive repopulation capacity.

129 nfection, and excessive exposure reduces HSC repopulation capacity.

130 stem cells (HSCs) has revealed variations in repopulation characteristics.

131 pretreatment significantly accelerated liver repopulation, compared to control rats.

132 l engraftment led to greater extent of liver repopulation, compared to drug-untreated controls.

133 s (hESCs) lack HOXA expression compared with repopulation-competent human cord blood CD34(+) cells, i

134 ditioned with ischemia decreased under liver repopulation conditions.

135 mechanism by which lymphocyte depletion and repopulation could reduce the risk of CoBRR.

136 we sought to examine whether G-CSF-mediated repopulation defects are a result of increased prolifera

137 to a similar PB phenotype and HSC-intrinsic repopulation defects.

138 result in significant long-term competitive repopulation deficiency.

139 Repopulation depends on the presence of hair cells and c

140 To account for repopulation during treatment, we considered two indepen

141 on produced profound lymphopenia followed by repopulation, during which naive IL-7Ralpha(+) CD57(-) P

142 cell ablation model in mice, we examined the repopulation dynamics of NG2(+) glial cells in the matur

143 ice, leading to at least a doubling of liver repopulation efficiencies.

144 Repopulation efficiency by LPC and/or biliary cells incr

145 estrogen-induced inflammation and adipocytes repopulation, estrogen-induced mammary cell death was vi

146 Using clonal repopulation experiments and computational-mathematical

147 competitive than control cells in long-term repopulation experiments, and overexpression of the self

148 pic as well as in vivo long-term competitive repopulation experiments.

149 ental data is provided by a model, where the repopulation failure kinetics of each HSC are largely an

150 ubsets and selectively delayed CD4(+) T cell repopulation following alemtuzumab-induced lymphopenia m

151 bone microenvironment associated with T-cell repopulation following ART initiation may explain ART-in

152 f BAFF in driving disease flare after B cell repopulation following BCDT.

153 hematopoietic niche by promoting competitive repopulation following lethal irradiation.

154 f human HSCs capable of multilineage in vivo repopulation following radiation injury.

155 Strikingly, however, monocyte repopulation for up to 6 mo did not modify amyloid load

156 rgeting of TSLP may interfere with tissue LC repopulation from circulating precursors.

157 be sustained solely by short-lived PCs with repopulation from clonally related memory B cells.

158 Lineage tracing was used to rule out repopulation from non-hepatocyte sources.

159 The liver regenerated through activation and repopulation from progenitors due to lineage-dependent d

160 s as those that have strong effects on liver repopulation, implicating the targeted hepatocyte miRNAs

161 insic B-cell defect, but in defective B-cell repopulation in a nonpermissive environment.

162 ransplantation would result in normal B-cell repopulation in case of intrinsic B-cell defect, but in

163 in this study will facilitate hematopoietic repopulation in FA patients with gene corrected HSPCs, o

164 s immediately following transplant and their repopulation in healthy allografts during the first mont

165 tion and tracking of subclinical bone-marrow repopulation in human beings and revealed new insights i

166 possessed the capacity to achieve long-term repopulation in lethally irradiated animals and the abil

167 epatocytes and substantially increased liver repopulation in retrorsine/partial hepatectomy model.

168 s also demonstrated improved engraftment and repopulation in serial transplantation assays.

169 ells may limit MS, rapid CD19+ B-cell subset repopulation in the absence of effective T-cell regulati

170 c or pharmacological microglial ablation and repopulation in the adult, indicating that local cues pl

171 est the impact of 43 selected genes on liver repopulation in the Fah(-/-) mouse model of hereditary t

172 he efficacy of cell engraftment and on liver repopulation in the mdr2-knockout mouse, a model for pro

173 eft eye, with probable host endothelial cell repopulation in the right eye.

174 engrafted poorly when tested by competitive repopulation in vivo.

175 uppressed human CML colony formation and CML repopulation in vivo.

176 We created a model for tumor cell repopulation in which a small number of luciferase-label

177 Interestingly, early after repopulation, infiltrating monocytes neither clustered a

178 rowth hormone augmented senescent host liver repopulation involving the growth hormone-mediated relea

179 ink that recipient BM-HSC-derived hepatocyte repopulation is a very rare event at best and is not of

180 evidenced that DR contribution to hepatocyte repopulation is at the most modest, unless replicative c

181 nd hence the understanding of melanoma tumor repopulation is crucial for improving our current therap

182 cts of HSC exposure to PGE2, we followed the repopulation kinetics of PGE2-treated hematopoietic graf

183 Post-depletion repopulation kinetics revealed AF(-) cells as likely pre

184 propose that impaired microglia death and/or repopulation may underpin dysregulated microglia activat

185 During repopulation, microglia formed clusters of highly prolif

186 nt animals, stem cells were rapidly lost and repopulation occurred by non-mutant cells that had escap

187 pletion of lung macrophages, the majority of repopulation occurred by stochastic cellular proliferati

188 Repopulation occurs in a coordinated pattern, first thro

189 Consequently, their repopulation occurs rapidly from irradiated progenitors

190 enic after chemotherapy, contributing to the repopulation of anti-CMV immunity.

191 ducing cytokines that directly enhance their repopulation of areas of demyelination and hence their a

192 While the coordinated repopulation of both hepatocyte and cholangiocyte compar

193 eostatic proliferation is involved in T-cell repopulation of both naive and memory T cells.

194 eased plasma viremia in all animals and that repopulation of CD8(+) T cells was associated with promp

195 y the bud sequence, is a major mechanism for repopulation of cirrhotic livers.

196 AOSLO imaging showed repopulation of cone outer segments, although their dens

197 zation efficiency of TM segments and lead to repopulation of conformational ensemble for the dimer.

198 ts, JAK inhibitors and bimatoprost stimulate repopulation of depleted cells in both diseases, intrale

199 a predominantly Near Eastern source for the repopulation of Europe after the Last Glacial Maximum.

200 donor-derived survival and recipient-derived repopulation of GCH transgenic ECs, revealed by tracking

201 However, smokers exhibit faster repopulation of Gram-negative bacteria.

202 Repopulation of LC-deficient mice using fetal liver LC-p

203 Whereas inflammation-induced repopulation of LCs appears to be dependent on Csf-1, on

204 cytokines, and dexamethasone accelerated the repopulation of liver phagocytes.

205 Finally, repopulation of lymphocyte-free Rag1(-/-) mice with CD40

206 tablish the feasibility of significant liver repopulation of mice with human hepatocytes generated in

207 1 receptor inhibitors induces depletion and repopulation of microglia, and corrects protein expressi

208 ic live cell imaging of muscle regeneration, repopulation of muscle stem cells within their endogenou

209 are capable of multi-lineage haematopoietic repopulation of myeloablated adult mice similarly to bon

210 ed genes, and licensed encapsulates promoted repopulation of recipient blood and bone marrow with all

211 l strategy for accelerating endothelial cell repopulation of stented blood vessels after angioplasty.

212 The lack of effective repopulation of Th17 cells has been associated with chro

213 1 and 3 months, but by 6 months, keratocyte repopulation of the anterior stroma was apparent.

214 row ablation, mutant animals exhibit delayed repopulation of the B-lymphoid compartment after the ear

215 spensable for B-cell development, B-lymphoid repopulation of the BM, and humoral immune function.

216 CD11b-HSVTK (TK) mice is followed by a rapid repopulation of the brain by peripherally derived myeloi

217 Microglial repopulation of the brain post-CSD reintroduced adverse

218 ls, summarizing the key pathways involved in repopulation of the epidermis with melanocytes in vitili

219 In conclusion, repopulation of the glomerular tuft by parietal cells ma

220 All charge-separated states lead to the repopulation of the ground state with dynamics that are

221 g nonradiative decay mechanism that promotes repopulation of the ground state.

222 CD4(+) T cell repopulation of the gut is rarely achieved in HIV-1-infe

223 ary approaches that prevent replenishment or repopulation of the HIV reservoir.

224 CA-FOXO3a and for maintaining hematopoietic repopulation of the HSCs.

225 interventions that prevent expansion and/or repopulation of the latent HIV reservoir.

226 Recent data in mice also show long-term repopulation of the LC compartment with alternative myel

227 neration was completely unaffected, although repopulation of the lesion site by astrocytes was delaye

228 provide for defect fill and/or selected cell repopulation of the lesion.

229 Repopulation of the liver with oval cells that expressed

230 Their repopulation of the matrix could promote the repair of c

231 However, although the repopulation of the optic nerve lesion site by astrocyte

232 s fitness and impedes natural and artificial repopulation of the oyster species within the Bay.

233 cline to induce Zap70 expression resulted in repopulation of the peripheral naive compartment.

234 glet nitrene, either directly or via thermal repopulation of the singlet from the lower-energy triple

235 modeling to estimate rates of microfilarial repopulation of the skin in a cohort of 217 participants

236 ntation into the extraction sockets to allow repopulation of the surgically treated root canal with p

237 ignal to protect their stem cells for future repopulation of the tissue.

238 vely from the donor, despite nearly complete repopulation of the transplanted lipogranulomas by host

239 tion in human HSCs by long-term multilineage repopulation of transplanted mice.

240 e JAK2V617F mutation and show no decrease in repopulation or self-renewal and no increase in DNA dama

241 Crypt repopulation originates from CBCs that survive irradiati

242 the clones analyzed contributed to long-term repopulation (over 3-10 years), arising in sequential gr

243 NS cells seem to be a good tool for scaffold repopulation, paving the way for experimental investigat

244 reatment with an IL-1R antagonist during the repopulation phase impaired microglia proliferation.

245 ith FL and adult HSCs, AGM HSCs have reduced repopulation potential in irradiated adult transplant re

246 that dormant HSCs contain all the long-term repopulation potential in the bone marrow (BM), and that

247 omeostasis, preserving HSC self-renewal, and repopulation potential in vivo and proliferation in vitr

248 ilure that correlated with reduced long-term repopulation potential of irradiated Parp-2-/- HSPC unde

249 notypic HSCs, we found reduced HSC long-term repopulation potential that could be rescued completely

250 e in the long-term-HSC pool, and a decreased repopulation potential.

251 or initiation capacity, and clonal long-term repopulation potential.

252 and increasing durable short- and long-term repopulation potential.

253 tion, accumulated with age in HSCs with high repopulation potential.

254 scid BM cells showed severely impaired repopulation potentials in the competitive repopulation

255 retrorsine (RS)-based model of massive liver repopulation, preexposure to this naturally occurring al

256 Here, microglial elimination/repopulation prevented the amplified immune reactivity e

257 NAC administration during repopulation prevented the behavioral decline in the rep

258 Administration of 1-MT prior to B cell repopulation prevented the production of autoantibodies

259 any clear association between microfilarial repopulation rate and the number of years of prior inter

260 atistically significantly high microfilarial repopulation rates.

261 The sequence of repopulation recapitulated the order of maturation in he

262 Microglia repopulation relied on CNS-resident cells, independent f

263 older animals failed to stimulate a similar repopulation response, possibly because of a decrease in

264 during the chronic phase of TBI followed by repopulation results in long-term improvements in neurol

265 emporal transcriptome profiling at different repopulation stages revealed that adult newborn microgli

266 transcription factor that confers definitive repopulation status on primitive hematopoietic progenito

267 Cs, B cells, and T cells under hematopoietic repopulation stress in vivo.

268 n controlling LT-HSC integrity in vivo under repopulation stress.

269 partial hepatectomy model was used for liver repopulation studies.

270 ntrol hepatocytes, especially in competitive repopulation studies.

271 n by rituximab, they show earlier and higher repopulation than CD20(+) B cells.

272 s also required for the efficient nucleosome repopulation that occurs after eviction, and the stronge

273 oved cell engraftment, and accelerated liver repopulation, this pharmacological approach to control h

274 Microglial repopulation throughout the CNS occurs through prolifera

275 t prostheses because of their rapid cellular repopulation, tissue remodeling, and therewith self-repa

276 ath of proinflammatory microglia followed by repopulation to a pro-regenerative state.

277 C function, we performed serial, competitive repopulation transplant experiments using FLVCR-deleted

278 isting in patients with low-level CD4 T-cell repopulation under suppressive high active antiretrovira

279 y depletes B cells, but is followed by rapid repopulation up to levels exceeding base line.

280 sive contribution to muscle repair and niche repopulation upon selective pressure of radiation stress

281 effect of ECM niche preservation on cellular repopulation using different scaffold generation methods

282 nt, we considered two independent 1) kickoff-repopulation using exponential growth with a decreased v

283 creased volume doubling time, or 2) Gompertz-repopulation using the gradually accelerating growth rat

284 ning transposons were quantified after liver repopulation via high-throughput sequencing.

285 Remarkably, more than 20% liver repopulation was achieved in the absence of PH, associat

286 Liver repopulation was assessed by immunohistochemistry, and t

287 cornea cleared, and central endothelial cell repopulation was documented by confocal microscopy.

288 Repopulation was quantified by flow cytometry and histoc

289 To discover novel regulators of HSPC repopulation, we transplanted >1,300 mice with shRNA-tra

290 ependent process, allowing reoxygenation and repopulation, whereas radiation was modelled as prolifer

291 progressive and invasive models of PDA, and repopulation with a Malassezia species-but not species i

292 phil-depleted WT recipients was sustained by repopulation with bone marrow neutrophils from WT mice b

293 occur, resulting from host endothelial cell repopulation with corneal clearing and improved visual a

294 nstrate decellularization of human liver and repopulation with derived human liver cells.

295 irrhotic hosts whose livers permit extensive repopulation with donor cells.

296 pair of cirrhotic livers occurs, in part, by repopulation with hepatocytes through the stem/progenito

297 Intestinal allograft mucosa undergoes repopulation with host immunocytes.

298 uman cytochrome metabolism is used following repopulation with human hepatocytes.

299 one or in combination enhanced hematopoietic repopulation without impairing myeloid-lymphoid differen

300 ional in vitro differentiation and long-term repopulation xenotransplantation assays.