ライフサイエンスコーパス: requirement for

1 Potential drawbacks include the requirement for 2 vaccine doses separated by 2-6 months,

2 ious in vivo studies due to the earlier FDX2 requirement for [2Fe-2S] cluster synthesis on ISCU2.

3 at do not rely on, or at least mitigate, the requirement for a battery are emerging at an astonishing

4 ifts and conflicting reports demonstrate the requirement for a discussion of the G1/S transition lite

5 ndependence owing to Shiny framework and the requirement for a minimal programming experience allows

6 imulation, we have investigated the pressure requirement for a nanoscale cavitation to grow in water

7 The requirement for a phosphoinositide is conventionally stu

8 measures are relaxed, possibly leading to a requirement for a second or more, repeated lockdowns(2).

9 the CUL4 adaptor protein DDB1, bypassing the requirement for a substrate receptor and presenting cycl

10 ope, though, is still limited to date by the requirement for a sufficiently potent target binder.

11 r of single walled carbon nanotubes, with no requirement for a treated substrate.

12 To address this challenge, we describe requirements for a framework for incremental data integr

13 vivo model to demonstrate cell-type-specific requirements for a particular viral gene.

14 ested parties around a clear set of goals or requirements for a potential product.

15 uctural, electrokinetic, and electrochemical requirements for achieving high anode reversibility.

16 These data help elucidate the molecular requirements for activation of SIRT6 and provide a found

17 2)Cys with TLR2 indicate that the structural requirements for activity are, for the most part, very i

18 ed in clathrin-mediated endocytosis, a clear requirement for actomyosin in clathrin-independent endoc

19 antibody recognition, it dispenses with the requirement for additional standard manipulations to dis

20 g these character count constraints with the requirements for adequate print size reveals that an ind

21 largely abolished demonstrating an essential requirement for adipocyte lipolysis in promoting stress-

22 However, there is no requirement for adjacent modules in either ring to be ac

23 patients, initial Ct did not correlate with requirements for admission or intensive care.

24 Among its general requirements for adolescents and recommendations for adu

25 losely mimicking physiological basal insulin requirement for an extended period following a single su

26 -stable and directly isolable, obviating the requirement for an extra synthetic transformation into m

27 NPR1 without induction of NPR1 expression or requirement for an increase in SA levels.

28 Here, 3D-printed labware can decrease the requirements for an experimentalist's time by >95%.

29 Sb(2)Se(3) semiconductor that satisfies most requirements for an ideal high-performance photoelectrod

30 Our aim was to investigate the critical requirements for an IgE recall response in peanut allerg

31 We discuss the ethical requirements for an intervention of this kind.

32 ana3 mutants are male sterile, reflecting a requirement for Ana3 for centriole development in the ma

33 This study defines the requirements for and mechanisms of noncanonical signalin

34 n is challenging to trace, and therefore the requirements for and order of coding sequence changes, e

35 This study defines for the first time the requirements for, and mechanisms of, signaling by IL6 in

36 e also revisit recommendations regarding the requirements for annotating sequences as new subtypes.

37 We further uncover a requirement for Argonaute proteins and Dicer, factors in

38 Regression suggested a minimum requirement for around 36 protein structural superfamili

39 processing and visual memory are fundamental requirements for artificial intelligence and robotics wi

40 with the associated environmental monitoring requirements for aseptic facilities, including compoundi

41 Inactivity was defined as requirement for assistance with activities of daily livi

42 ativity in ATP hydrolysis, and the energetic requirement for at least 12 ATP molecules to be hydrolyz

43 Little is known of the structural requirement for atropisomerism in structurally simpler s

44 rther contribute to our understanding of the requirements for autophagy during flavivirus infection.I

45 We compared the requirements for autophagy receptor proteins: OPTN, NBR1

46 synaptic plasticity and are unique in their requirement for binding of a coagonist, which is d-serin

47 agnosis of hypertension as determined by the requirement for blood pressure treatment early postdonat

48 hift in redox potential is attributed to the requirement for both an open-shell metal ion and a redox

49 omer localization and function, highlighting requirements for brain homeostasis in aging.

50 Although much is understood about the requirements for Bub1 and BubR1 interaction with Bub3 an

51 e addressed this unknown with respect to the requirement for Ca(v)1.4 L-type channels for the formati

52 different transmission routes and determine requirements for case isolation and contact tracing need

53 DNA synthesis is a fundamental requirement for cell proliferation and DNA repair, but n

54 As one of the fundamental requirements for cell growth and proliferation, nitrogen

55 ated that the Callascope camera meets visual requirements for cervical imaging.

56 ies, whereas its overexpression bypasses the requirement for chlamydosporulation cues and regulators.

57 of carotenoids are not just consequences but requirements for chloroplasts to differentiate into chro

58 Here we outline underlying requirements for codependency, compare important drivers

59 An additional requirement for confidence representations to support me

60 Finally, requirements for constructing a computer graphics quanti

61 CF interacts with cohesin which explains the requirement for convergent CTCF binding sites in loop fo

62 Here, we analyze the requirements for core CPC subunits, survivin and INCENP,

63 t (5(*+)) does not meet the stereoelectronic requirements for cyclopropane ring opening.

64 distributions show MQNs are consistent with requirements for dark matter and indicate that geologic

65 tinct navigational variables, fulfilling the requirements for dendritic computation.

66 tudies provide new insight into the sequence requirements for developing novel CPPs for transcellular

67 ophil activation test [BAT]) might meet this requirement for different IgE-dependent allergies and pa

68 ptors to mediate infection, but the specific requirements for different cell types are not entirely k

69 However, the requirements for differentiation into mature RPMs remain

70 ber of individual reaction partitions, a key requirement for digital nucleic acid analysis.

71 Significant evidence also suggests a requirement for direct, drug-induced stress, neoantigen

72 ch is a key virulence factor and an absolute requirement for disease.

73 cy, raising the possibility that the minimal requirement for DNA double-strand break (DSB) formation

74 ic reporter assay, our results demonstrate a requirement for dnmt1 activity in the regulation of RSC

75 tions are insufficient to define the minimal requirements for domain formation.

76 rther revealed potential subcircuit-specific requirements for dscaml1 during oculomotor behavior.

77 assays further establish a significant RUNX1 requirement for E2A-PBX1-mediated target gene activation

78 zed', rather than general, subset of histone requirements for each chromatin context.

79 aspects of Gle1A and Gle1B function, and the requirements for each interaction domain differ.

80 NKT subsets, underlining a dichotomy between requirements for early activation vs subsequent prolifer

81 ed as being essential for thermogenesis, its requirement for efficient thermogenesis has not been dir

82 Determining the requirements for efficient oxygen (O(2)) activation is k

83 e, imposing stringent structural and kinetic requirements for efficient primer strand transfer.

84 to provide energy and essential biosynthetic requirements for efficient replication.

85 energy-restricted diet (788 kcal/d below the requirement) for eight weeks in a free-living contest.

86 storage devices to meet the demanding market requirements for electric vehicles.

87 k era, but only conventional metals meet the requirements for emerging radio-frequency (RF) devices s

88 These findings reveal a new requirement for endothelial TGF-beta signaling in OFT mo

89 utputs are regulated to balance the cellular requirement for energy and heat is largely unknown.

90 n and reduced IR pathology, suggesting a key requirement for enhanced neutrophil C5aR1 activation in

91 Delphi survey with a focus on methodological requirements for establishing benchmarks for surgical ou

92 hree complementary approaches to explore the requirement for EXOSC5 in brain development and assess c

93 The requirement for FACT then depends on the level of chroma

94 ps and smooth edges) and mechanical-strength requirements for failure-free penetration of human and m

95 fluid and diet modification and supervision requirements for feeding, is used for clinical research

96 induced bone loss occurs due to high calcium requirements for fetal growth but skeletal recovery is n

97 LI), using an amended definition without the requirement for fever.

98 ive validation and no ability to predict the requirement for fibrinolytics or thoracic surgery.Object

99 cid-like sugar pseudaminic acid and show its requirement for flagellation, flagellin modification and

100 However, the requirement for freshly isolated mitochondria hinders th

101 plains observed seismic wave partitioning, a requirement for full-wave field ambient-noise tomography

102 vidual 3Bs to replication and the structural requirements for functionality.

103 lity, and high cost, are facing ever-growing requirements for further increases in power capability,

104 a lipid signaling molecule in plants with a requirement for G-proteins to mediate signal transductio

105 for broader patient administration without a requirement for G6PD diagnosis.

106 tricted temporal efficacy of HSCT reflects a requirement for GALC in early brain development.

107 Cell-specific deletion reveals a requirement for GATA6 in various SAN lineages.

108 To explore requirements for gB's fusion activity, we generated a se

109 The requirement for GBF1 implies that Arfs are important for

110 euromorphic completeness', which relaxes the requirement for hardware completeness, and a correspondi

111 substrates in radical processes despite its requirement for hazardous reagents and initiators such a

112 the target cytosine bypass the SNF2 domain's requirement for hemimethylation.

113 the semiconductors were able to assuage the requirement for high energy (> 40 keV) large-area X-ray

114 finity trend and site-specific glycosylation requirements for high affinity binding to these lectins.

115 heds light on the design of cation transport requirements for high-energy reversible cathodes in aque

116 We further unmask a mutual requirement for Hivep3, a zinc finger transcription fact

117 Our work establishes requirements for homeostatic cDC2 positioning in the spl

118 , (b) severe COVID-19 infection defined as a requirement for hospitalization and oxygen therapy, (c)

119 cteria, which colonize the gut, bypasses the requirement for host tyramine biosynthesis and manipulat

120 rovided opportunities to define nonredundant requirements for host defense against EBV infection.

121 loci and explain how Cas12c/d systems avoid requirements for host factors including ribonuclease III

122 Our findings reveal a requirement for HP1gamma in faithful establishment of tr

123 Access to healthcare is a requirement for human well-being that is constrained, in

124 in China, which explicitly includes quality requirements for human water uses.

125 tabolic heat (H(prod)) production, and water requirements for hydration, during space exploration mis

126 hat reduced exocyst function bypassed the PT requirement for Hyp-Ara.

127 These data provide insight into the requirements for IFN-gamma production and how IFN-gamma

128 ectively, these findings suggest an obligate requirement for IL-11 signaling via constitutive pS-STAT

129 to our knowledge, we discovered an intrinsic requirement for IL-18 signaling by splenic iNKT cells bu

130 dies in human OCCA cell lines to explore the requirement for IL6 in vitro and in vivo.

131 arking individual insects in groups, relaxes requirements for image size and quality, and makes the s

132 o the nuclear theranostic model by showing a requirement for imaging to quantify, in situ, the concen

133 While the essential requirements for immune activity are well understood, th

134 The requirement for immunopathologic confirmation of MMP by

135 n, the authors discuss the main concepts and requirements for implementing continuous AI in radiology

136 This is an essential requirement for inactivation of multiple copies of disea

137 based fertilizers, which have been driven by requirement for increased food production, but which als

138 However, the context-dependent requirement for individual glycolytic steps has not been

139 appendage generation and reveals a range of requirements for individual TREEs in control of regenera

140 ilable due to a lack of understanding of the requirements for induction of fully protective immunity.

141 istinct modes of NPC division have divergent requirements for Ino80-dependent HR DNA repair.

142 Pseudomonas aeruginosa exhibits a high requirement for iron, which it can acquire via several m

143 However, the bottleneck imposed by the requirement for isolates precluded genomic insights for

144 bly well understood, less is known about the requirements for its establishment.

145 to the vacuolar membrane by glucose, but the requirements for its recruitment are not understood.

146 In turn, we also demonstrate a requirement for Kif3a, a gene essential for the formatio

147 In addition, we identified a differential requirement for LAMTOR4 and LAMTOR5 in regulating the mT

148 uring an algorithm, correcting them is a key requirement for large-scale and fault-tolerant quantum i

149 Our results identify a critical requirement for Ldb1 in Lmo2-induced thymocyte self-rene

150 However, the requirement for life-long immunosuppression and its asso

151 ficient energy transfer, which is a critical requirement for light-emitting devices.

152 ences in the surface of CD1b recognized, the requirement for lipid antigens, and corecognition of but

153 enforces cargo specificity and replaces the requirement for lipidated LC3.

154 ce, staggered-end DNA target cleavage, and a requirement for long stretches of homology between gRNA

155 ransplantation is cellular rejection and the requirement for long-term immunosuppression.

156 was a composite of death from any cause or a requirement for long-term oxygen therapy as defined by t

157 calized on the oxo ligand is not an inherent requirement for low C-H activation barriers.

158 We identify a transient requirement for LSD1 in endocrine cell differentiation s

159 r H+-ATPase gene atp6ap1b, revealed specific requirements for luminal acidification in apical, but no

160 Our results describe a requirement for MAFB late in the human pancreatic develo

161 The molecular requirements for MALT1 monoubiquitination and the mechan

162 criptional induction and reveal differential requirements for MAML1-dependent recruitment activities

163 This is the requirement for mass transfer to the electrode, which gi

164 Clarifying the requirements for maximal cytotoxic capacity is critical

165 from ward to intensive care unit (ICU), new requirement for mechanical ventilation, and mortality.

166 together, our data support a cell-autonomous requirement for Med23 in neural crest cells, potentially

167 emonstrate methods to estimate the financial requirements for meeting this commitment in urban settin

168 ur demonstration relaxes the instrumentation requirement for microcomb repetition rate detection, and

169 In this review, the requirements for molecular receptors and probes for envi

170 To uncover the minimal requirements for morphogen gradient formation, we have e

171 resulting from phase separation reduces the requirement for motif specificity and expands the repert

172 Genetic requirements for Msh4 phosphorylation indicate that DDK

173 ing redundancy in Gag-RNA interactions and a requirement for multiple Gag binding on viral RNA during

174 lack PTEN expression, there is no consistent requirement for mutation in TP53, RB1, BRCA2, PIK3CA, or

175 es of amplicons which explain the regulatory requirements for MYCN overexpression.

176 However, the true requirement for myeloid cells in PH development has not

177 Intriguingly, the requirement for MYO7B in endocytosis is restricted to al

178 for large-area BP films that meet industrial requirements for nanodevices applications.

179 Here, we investigate a local requirement for NCOA4 in the regulation of hepatic iron

180 overed in these studies reveals an essential requirement for NCSTN during the type 2 transitional-mar

181 quiv of boron from the diboron reagent and a requirement for neat substrate.

182 novel mouse models of human lupus inform the requirements for nephritis and provide targets for inter

183 te formation in mouse neuroblastoma cells, a requirement for neurogenesis.

184 and memory in adulthood, despite the lack of requirement for neuronal survival.

185 These data provide strong evidence for a requirement for notch signaling in specification of the

186 rved form of learning, highlighting that the requirement for O-GlcNAcase activity for cognitive funct

187 a 15 s' response time, which can satisfy the requirement for on-site detection and field diagnosis of

188 s between the magnitude of expansion and the requirement for ongoing immunogenic stimulation.

189 The results illustrate the requirements for optimization of each enzyme's loading a

190 t is more consistent with federally mandated requirements for organ allocation.

191 Chilling requirements for overcoming winter endodormancy were str

192 und a strong correlation between the genetic requirements for P. ananatis to colonize necrotized onio

193 on of PAK1 alone, consequently, the relative requirement for PAK1 and PAK2 in whole-body glucose home

194 copy and cultured PDGFRalpha+ cells reveal a requirement for PCP in their oriented cell migration gui

195 and type 2 pathways, alleviating the aerobic requirement for PDT.

196 fish, indicating an evolutionarily conserved requirement for PERK in sleep.

197 ing S. Typhimurium, indicating that the SsrB requirement for PhoP/PhoQ activation is signal-dependent

198 s in vivo and in vitro, we fail to observe a requirement for phosphorylation in NLRC4 inflammasome fu

199 Understanding the physiological requirements for photoreceptor homeostasis and the facto

200 The only known requirements for PIC targeting are a Gram-negative cell

201 be tailored as a diagnostic test to meet the requirements for point-of-care cell-free tumor DNA (ctDN

202 We demonstrate a requirement for positive transcriptional autoregulatory

203 pleural effusion, pneumothorax, or unplanned requirement for postoperative invasive or noninvasive ve

204 power gradient drivers, lowering the overall requirements for power and cooling, and reducing acousti

205 This requirement for PP1 is lost in cells expressing CDK1 pho

206 Here, we report an essential requirement for PRDM10 in pre-implantation embryos and e

207 lopment of new drugs or compounds there is a requirement for preclinical trials, commonly involving a

208 sites for specific TFs automatically with no requirement for pregenerated candidate binding sites or

209 We identify a localized requirement for prenylation in sympathetic axons to prom

210 Thus, the requirement for primary cilia presents a conundrum: how

211 and review best practices and US regulatory requirements for privacy and security.

212 se reductions varies as a function of energy requirements for production, process-related emissions f

213 en electroluminescent devices, including the requirement for proper alignment of material energy leve

214 Guided by the genetic requirements for proper cable assembly and dynamics, we

215 of genes that are induced, underscoring the requirement for proteasome activity at multiple phases o

216 ARF), ETTIN towards target genes without the requirement for protein degradation.

217 le compound-HLA class II interaction with no requirement for protein processing.

218 These data demonstrate that the requirement for Rad26 in TC-NER is modulated by the dist

219 The energy requirements for recycling copper from end-of-life produ

220 ional Council for Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Hum

221 with longer ICU or hospital length of stays, requirement for renal replacement therapy, longer durati

222 EPN-HEPN' chimeras, we defined the molecular requirements for RNA cleavage.

223 These results establish a TFIID requirement for RNAPII pausing and suggest pause regulat

224 receptor tyrosine kinases (RTKs) and found a requirement for RTK-like orphan receptor (Ror).

225 al provide novel molecular insights into the requirement for Runx1 in a mouse model of inv(16) acute

226 up and Rhesus D status, the need for special requirements for selected recipients, and the necessity

227 sphatidylinositol biosynthesis, as well as a requirement for several poorly characterized proteins.

228 idinium carterae was sufficient to support N requirements for several new generations.

229 Our work describes a previously unknown requirement for Sfxn3 in retinal function.

230 We find a specific requirement for Shrub in maintaining septate junction (S

231 We identified the cause of the S-phase requirement for silencing establishment: removal of tran

232 esults, HML and HMR had identical cell-cycle requirements for silencing establishment, with no appare

233 highly challenging because of the stringent requirement for simultaneous recognition of the pY motif

234 Nrf2 bZIP transcription factor; however, the requirement for SKN-1 in endoderm specification varies w

235 iers from 3 to 6 and added cardiogenic shock requirements for some heart transplant candidates listed

236 These results indicate a stage-specific requirement for Sp2 in neural stem and progenitor cells,

237 aration is one way cells meet the biological requirement for spatiotemporal regulation of cellular co

238 including short reaction times, low cost, no requirement for specialized equipment, and highly clear

239 n both oscillators, arising as a fundamental requirement for sperm chemotaxis.

240 al and rRNA function, accommodating changing requirements for splicing and protein synthesis during h

241 on is proposed to originate in part from the requirement for stronger oxidants, leading to a smaller

242 The critical requirement for strongly acidic conditions was rationali

243 in many common features and this enables key requirements for successful C-H borylation and the facto

244 Nevertheless, the requirements for successful therapy remain effective del

245 a "trademark" for DNA damage responses, the requirement for such dramatic protein stabilization in t

246 cytomegalovirus infection, and consider the requirements for such a response in NK cells in light of

247 However, the requirements for such de novo centromere formation and t

248 unique optimal configuration which meets the requirements for superdirective emission.

249 Kinetic studies also demonstrate the requirement for sustained PI supply from the ER for the

250 tations initiate FL by attenuating GC B cell requirement for T cell help and driving slow expansion o

251 aring birds appears to be constrained by the requirements for takeoff.

252 ons when defining institutional and operator requirements for TAVR across the country.

253 otubules at low temperatures and rescues the requirement for TBCB/Alf1 in maintaining microtubule pol

254 how that this likely results from an earlier requirement for Tbx1 in ventral cardiac LEC progenitors.

255 vitro, newborn Tregs exhibited an increased requirement for TCR engagement for survival.

256 ertain if this group is a key pharmacophoric requirement for the antileishmanial bioactivity.

257 ed1 interactions with eIF4A/eIF4E unveiled a requirement for the Ded1-CTD for robust initiation.

258 ding question of how MT-4 cells overcome the requirement for the HIV-1 gp41 CT and support a role for

259 The requirement for the HSP70 ATP cycle in ubiquitination su

260 These data demonstrate a requirement for the inhibition of Polo, perhaps by seque

261 1650-1665) now shows a requirement for the intrinsic clock in the regenerative

262 the identification of the minimum structural requirement for the macrocyclization and assembly proces

263 d the centromere receptor CENP-C without the requirement for the Mis18 complex.

264 operationalizing aspects of it, such as the requirement for the objective demonstration of axial inf

265 mediated tonic signaling is an indispensable requirement for the survival of follicular B (FOB) cells

266 ctive visuomotor coordination is a necessary requirement for the survival of many terrestrial, aquati

267 e able to acclimate over time and bypass the requirement for the TonB outer membrane transporter to a

268 ct on maturation complex stability and their requirement for the transition to active packaging motor

269 We identified an absolute requirement for the VMP1, TMEM41, and TMEM64 (VTT) domai

270 Some of the outstanding requirements for the application of these dynamic materi

271 Altogether, our results highlight the common requirements for the development of innate-like T cells

272 and functional BAX(O), revealing structural requirements for the elusive execution phase of mitochon

273 te the in vivo sequelae of the cell-specific requirements for the functions of AK2 and mitochondria,

274 gical perturbations in individuals with NKD, requirements for the generation of terminally mature fun

275 a literature review to define the ecological requirements for the growth of both truffle species.

276 These findings highlight the stage-specific requirements for the presumed "general" coregulators Sin

277 r-dispensing robotics to meet drug discovery requirements for the screening of large and diverse comp

278 nnate-like lymphocytes with unique signaling requirements for their development and differentiation.

279 Thus, a better understanding of the cellular requirements for their infection is needed.

280 is little quantitative understanding of the requirements for their nuclear import, especially the ro

281 conventional electrical wiring, relaxing the requirements for thermal anchoring, and is also immune t

282 chromatin dynamics, yet its general in vivo requirement for these functions is unknown.

283 per cell, ~100-fold lower than minimum iron requirements for these cells (~5,100 atoms per cell).

284 Systematic analysis revealed that requirements for these Grs differed for the same tastant

285 The gustatory requirements for these opsins are light-independent and

286 The key requirement for this process is to develop filter materi

287 vident, highlighting differing developmental requirements for this core replisome component that warr

288 vely manage measurement results to eliminate requirements for time-consuming and user-dependent image

289 from 10 countries to reach consensus on the requirements for TO in pancreatic surgery.

290 are both highly conserved among mammals, the requirement for two different cellular cofactors suggest

291 ort quality assurance protocols, including a requirement for two engine turbine-powered aircraft pilo

292 ch leads to a 30-fold reduction in the power requirement for two- or three-photon imaging of brain ac

293 Here, we identify a requirement for unpaired-JAK signalling as a metabolic r

294 tract illness with high rates of pneumonia, requirement for ventilatory support, and short- and long

295 mbrane homeostasis and suggest an unexpected requirement for VLCFAs in Ole1 function.

296 Such differential requirements for VPL to improve the detectability of les

297 cell lines support that endocytosis is not a requirement for Wnt signal transduction.

298 somes bearing R- or Qa-SNAREs shows a strict requirement for Ypt7 on the R-SNARE proteoliposomes but

299 ressed resources, as well as strict clinical requirements for ZIKV detection.

300 To define the sequence requirements for ZMPSTE24 cleavage, we mutagenized the e