ライフサイエンスコーパス: resorb

1 lerates G1-S progression by causing cilia to resorb.

2 he flagellar tips and causes the flagella to resorb.

3 of its mRNA are present as the tadpole tail resorbs.

4 sts, which form new bone to replace what was resorbed.

5 rk of collapsed tonoplast membranes that are resorbed.

6 of the ectopic MYC-positive structures were resorbed.

7 reduced the number of pits and surface area resorbed.

8 ysosomes, was depleted as they tubulated and resorbed.

9 sapotexanthin, cryptocapsin was found to be resorbed.

10 rapidly remodeled and reoriented, as well as resorbed.

11 The PEUU patch was largely resorbed 8 weeks after implantation and the LV wall was

12 Each NRK preferentially resorbed a distinct subset of cilia, depending on the lo

13 amino acids; for instance, droughted plants resorbed a smaller fraction of elemental N from their le

14 planted and, although most were subsequently resorbed, a significant proportion (2 to 2.8%) developed

15 ( D301N) expression enhances osteoclast bone resorbing ability through reorganization of actin cytosk

16 transition to stationary phase, they instead resorb acetate, activate it to acetyl coenzyme A (acetyl

17 ucial mediator of both bone-forming and bone-resorbing actions of PTH, and they underline the complex

18 60 with potent leukocyte-activating and bone resorbing activities.

19 ression of dynamin increased osteoclast bone resorbing activity and migration, whereas overexpression

20 with ST2 showed increased production of bone-resorbing activity and neutralizing antibodies against V

21 ritic cells; and increases osteoclastic bone-resorbing activity as well as osteoclast chemotaxis.

22 By contrast, cavities with low bone-resorbing activity do not harbour expanding HSCs.

23 est that calcitonin inhibits osteoclast bone resorbing activity in part by down-regulating calpain ac

24 om Nlrp3-deficient macrophages had increased resorbing activity in vitro.

25 se of 1,25(OH)(2)D(3), it has much less bone resorbing activity in vivo.

26 The bone-resorbing activity of both porins was not inhibited by t

27 The motility and resorbing activity of mu-calpain(-/-) osteoclast-like ce

28 inase-dead Pyk2, markedly inhibited the bone-resorbing activity of wild type osteoclasts and failed t

29 sts and failed to significantly restore bone-resorbing activity to Src(-/-) osteoclast-like cells.

30 te-resistant acid phosphatase staining; bone resorbing activity was assessed by using an osteologic p

31 on of the c-src gene impairs osteoclast bone resorbing activity, causing osteopetrosis.

32 t in osteoclasts markedly reduced their bone resorbing activity, suggesting that phosphorylation of C

33 ultinucleated giant cell phenotype with bone resorbing activity.

34 d the microtubule network and decreased bone-resorbing activity.

35 an important role in osteoclast motility and resorbing activity.

36 produced increased osteoclastogenic and bone-resorbing activity.

37 This material contained potent bone-resorbing activity.

38 obtained, concentrated, and assayed for bone-resorbing activity.

39 hesis that NH2-terminal PTHrP, a potent bone resorbing agent, could also be a member of the synovial

40 ud, zooids from the old generation were also resorbed, albeit delayed to 48-60 h following onset of p

41 elayed, formed no mesoderm by E7.5, and were resorbed almost completely at E8.5.

42 cells, in turn, fuse to form osteoclasts to resorb alveolar bone for the formation of an eruption pa

43 In contrast, plants in drought treatment resorbed amino acids more efficiently (>90%) than those

44 mmersed in connective tissue and appeared to resorb and be replaced by bone.

45 e-sensitive mutant, fla10, existing flagella resorb and new flagella cannot be assembled.

46 deling, bone-embedded osteocytes dynamically resorb and replace the surrounding perilacunar bone matr

47 ilica biomaterials is the rate at which they resorb and the significant role played by interfacial ch

48 s, made entirely of materials that naturally resorb and undergo clearance from the body after a contr

49 Bone is constantly resorbed and formed throughout life by coordinated actio

50 Autologous bone will eventually be resorbed and replaced by the host.

51 becular bone turnover due to imbalanced bone-resorbing and bone-forming activities is a hallmark of o

52 peak of metamorphic climax just before it is resorbed are suppressed in the transgenic limb muscle in

53 correlated with tissues that either grow or resorb at metamorphosis.

54 elop a functional heart tube at E8.5 and are resorbed at approximately E10.5.

55 died abruptly at Day 13, and all were being resorbed at Day 14 of development.

56 (E)7.5, they die by E8.5, and are completely resorbed at E11.5.

57 on, together with its serotonergic cells, is resorbed at metamorphosis.

58 stages of gastrulation and they die and are resorbed between E9.5 and E10.5.

59 Cx3cr1(neg) i-OCLs have a high ability to resorb bone and activate inflammatory CD4(+) T cells.

60 eoclasts (OCs) are multinucleated cells that resorb bone and are essential for bone homeostasis.

61 creased ability of osteoclasts to invade and resorb bone and mineralized cartilage in vivo.

62 crophage/monocyte lineage-derived cells that resorb bone and NF1 haploinsufficient osteoclasts have a

63 S. aureus directly enhanced their ability to resorb bone by promoting cellular fusion.

64 st-natally to form the osteoclasts needed to resorb bone for the eruption pathway.

65 erentiate into multinucleated osteoclasts or resorb bone in vitro and show impaired phosphorylation o

66 ma2 (SH2(N+C)) failed to form mature OCs and resorb bone in vitro.

67 defective ruffled borders and were unable to resorb bone in vitro.

68 The capacity of the osteoclast (OC) to resorb bone is dictated by cytoskeletal organization, wh

69 Osteoclasts from these mice resorb bone matrix poorly, and the structure, stability,

70 Osteoclasts resorb bone through the formation of a unique attachment

71 In particular, osteoclasts resorb bone via a receptor activator of nuclear factor k

72 Osteoclasts resorb bone via the ruffled border, whose complex folds

73 reviously shown that osteoclasts, cells that resorb bone, act as APCs.

74 n animal by the action of osteoclasts, which resorb bone, and osteoblasts, which form new bone.

75 syndromes indicate that osteoclasts not only resorb bone, but also provide signals to promote bone fo

76 eoclasts are multinucleated giant cells that resorb bone, ensuring development and continuous remodel

77 ells work in harmony with osteoclasts, which resorb bone, in a continuous cycle that occurs throughou

78 ch is central to the capacity of the cell to resorb bone, is induced by occupancy of the alphavbeta3

79 y of cytokines that stimulate osteoclasts to resorb bone, leading to cancer-mediated destruction of t

80 To resorb bone, OCs form podosomes.

81 steoclasts differentiate from precursors and resorb bone, the identity of an osteoclast precursor (OC

82 s unknown, directly activates osteoclasts to resorb bone.

83 th altered morphology and reduced ability to resorb bone.

84 ly differentiate into mature osteoclasts and resorb bone.

85 nto which they secrete acid and proteases to resorb bone.

86 r influence on the ability of osteoclasts to resorb bone.

87 cells and decreased ability of the cells to resorb bone.

88 ROS stimulate osteoclasts, the cells that resorb bone.

89 g from defective osteoclasts, the cells that resorb bone.

90 tiation of osteoclasts and their capacity to resorb bone.

91 ) in stimulating mouse marrow osteoclasts to resorb bone.

92 te the reduced ability of the osteoclasts to resorb bone.

93 ide channel as the cells become competent to resorb bone.

94 that fuse to form multinuclear cells able to resorb bone.

95 specifically in osteoclasts, the cells that resorb bone.

96 rm small actin rings and fail to effectively resorb bone.

97 ly have normal cytoskeletons and effectively resorb bone.

98 ce, which do not form actin rings and do not resorb bone; (e) PYK2 phosphorylation by exogeneous c-Sr

99 Under most conditions, resorbed bone is nearly precisely replaced in location a

100 Osteoclast cultures resorbed bone slices and calcium phosphate substrate.

101 uted tomography (uCT) in terms of formed and resorbed bone volume.

102 Osteoclasts, the cells capable of resorbing bone, are derived from hemopoietic precursor c

103 ct in osteoclasts, the cells responsible for resorbing bone.

104 during aging when TGFbeta1 is released from resorbing bone.

105 Purification of YKL-40 from resorbing bovine nasal cartilage and chondrocyte monolay

106 evelop beyond the egg cylinder stage and are resorbed by 10.5 days of gestation, a phenotype consiste

107 lumen over 12 months in vivo and also fully resorbed by 18 months in the ovine model.

108 arrested after 5.5 days postcoitum (dpc) and resorbed by 8.5 dpc.

109 mmalian inner ear, endolymph is produced and resorbed by a complex series of epithelia.

110 ever, virtually all of these pregnancies are resorbed by dpc 8.5.

111 ing 12 micrograms of atRA per g of diet were resorbed by E18.5, whereas those in the group fed 250 mi

112 5 days gestation (E5.5) and were completely resorbed by E8.5.

113 ive streak stages but fail to thrive and are resorbed by E9.5.

114 However, the amount of bone resorbed by osteoclasts stimulated by 10 nM 19-norD(2),

115 Excess potassium ions in the Corti fluid are resorbed by supporting cells to maintain fluid homeostas

116 nd need not be removed as they are gradually resorbed by the tissue.

117 are phenotypically defective being unable to resorb calcification.

118 to determine if PRP combined with a rapidly resorbing cancellous allograft would enhance the regener

119 oclasts are the only somatic cells with bone-resorbing capacity and, as such, they have a critical ro

120 We found that the functional bone resorbing capacity was severely impaired in OCLs deplete

121 The addition of Dec-RVKR-CH(2)Cl to resorbing cartilage also partially blocked proteoglycan

122 three isoforms, a major and minor form from resorbing cartilage and a third species from chondrocyte

123 al cells, not osteoclasts, are essential for resorbing cartilage to lead directional bone growth.

124 that GW9508, a GRP40 agonist, abolished bone-resorbing cell differentiation.

125 The osteoclast is the principal bone-resorbing cell.

126 xpressed in the osteoclast, the primary bone-resorbing cell.

127 ed in the recruitment and activation of bone resorbing cells associated with focal bone erosions.

128 ent the development of OCPs into mature bone-resorbing cells could simultaneously prevent bone resorp

129 Osteoclasts are bone-resorbing cells derived from hematopoietic precursors of

130 Osteoclasts (OC) are bone-resorbing cells derived from the monocyte/macrophage lin

131 Osteoclasts are bone-resorbing cells essential for skeletal development, home

132 Osteoclasts are bone-resorbing cells essential for skeletal remodeling.

133 In conclusion, the resorbing cells in RA exhibit a definitive osteoclastic

134 Osteoclasts are bone resorbing cells of hematopoietic origin; however, a prog

135 ancer grows, osteoclasts, the principal bone-resorbing cells of the body, are recruited to and activa

136 ed myeloid cells that are the principal bone-resorbing cells of the skeleton.

137 Osteoclasts (OCs) are bone-resorbing cells that are formed from hematopoietic precu

138 Osteoclasts are bone-resorbing cells that are important for maintenance of bo

139 Osteoclasts are specialised bone resorbing cells that control both physiological and path

140 ly induce apoptosis in osteoclasts, the bone resorbing cells, and this may play a role in inhibition

141 Osteoclasts, the only bone-resorbing cells, are central to the pathogenesis of oste

142 Osteoclasts are bone-resorbing cells, but they also secrete and respond to cy

143 of increased numbers of osteoclasts, or bone-resorbing cells.

144 apoptosis of osteoclasts, the principal bone-resorbing cells.

145 Osteoclasts are the sole bone-resorbing cells.

146 amined release of ECM-bound TGF-beta by bone resorbing cells.

147 d activation of osteoclasts, the normal bone-resorbing cells.

148 one-forming cells, and osteoclasts, the bone-resorbing cells.

149 tures assume organization typical of active, resorbing cells.

150 where they fuse to form multinucleated bone-resorbing cells.

151 Because most cells resorb cilia/flagella before cell division, these data i

152 ich assembled cilia at high cell density and resorbed cilia at low cell density.

153 he treated root surface height for the rapid-resorbing collagen and 53% for the ePTFE membrane (diffe

154 It was concluded that the rapid-resorbing collagen membranes and the ePTFE membranes see

155 l connective tissue repair, whereas the slow-resorbing collagen membranes were unsuccessful in this e

156 mination of root surfaces treated with rapid-resorbing collagen or ePTFE membranes revealed substanti

157 ately 50% of the surfaces of the bone slices resorbed compared with only 6% in cultures treated with

158 as early as embryonic day 4.5 (E4.5) and are resorbed completely by E8.5.

159 and thus the amount of bone that osteoclasts resorb could also be enhanced following estrogen deficie

160 (AgP) gingival fibroblasts produce the bone-resorbing cytokine IL-6.

161 ion, expression of the proinflammatory, bone-resorbing cytokine interleukin-6, and in vitro bone reso

162 teoclasts in vitro, but not their ability to resorb dentin.

163 one-like tissue was found within lesions, on resorbed dentin, or on the root surface in 27% of teeth.

164 ere markedly impaired in their ability to be resorbed despite engulfment of zooid-derived cell corpse

165 iated into bone during the healing phase but resorbed during remodeling.

166 hilic line and bone necrosis that was slowly resorbed during the repair process.

167 No resorbed embryos were found at embryonic day (E) 17.5, i

168 This failure to resorb established calcifications may contribute to the

169 ough their capacity to deposit, remodel, and resorb extracellular matrix and to promote tissue vascul

170 MMP13, VEGF, Osteopontin) and secreted bone-resorbing factors (PTHrP, IL8) promoting osteolytic dise

171 rrow precursor cells in the presence of bone-resorbing factors, indicating that OSCAR may be an impor

172 y for maximal OCL formation by multiple bone resorbing factors.

173 ll formation in the presence of several bone-resorbing factors.

174 interstitial fluid, salts, small molecules, resorbed fat, and cells to the bloodstream.

175 methylated proteins have been identified in resorbing flagella, using antibodies specific for asymme

176 sed in regenerating flagella, and highest in resorbing flagella.

177 and efficient removal of interstitial fluid resorbed from the loop of Henle and collecting ducts.

178 mation of the sealing ring and thus the bone-resorbing function of osteoclasts.

179 TR1 also strongly inhibited bone-resorbing function on dentine slices by mature osteoclas

180 o the facile formation of multinucleate bone-resorbing giant cells.

181 C filter can be safely deployed in swine and resorbs gradually over the 32-week testing period.

182 ts/stromal cells in response to various bone resorbing hormones.

183 occluded artery for 6 mo and are completely resorbed in 2 y.

184 ied of apparent infection, and all kits were resorbed in another animal that did not die.

185 The pancreatic pseudocyst was resorbed in eight months.

186 e and then allowing the silk to dissolve and resorb initiates a spontaneous, conformal wrapping proce

187 completion of function, the device is safely resorbed into the body, within a programmable period.

188 tadpole completed its metamorphosis without resorbing its tail.

189 re involved in pulling up the "back end" and resorbing lamellipodial membrane protrusions.

190 -OCLs are associated with inflammation, they resorb less and have in vitro an immune-suppressive effe

191 n by facilitating growth factor release from resorbed matrix, producing secreted proteins and microve

192 predictable augmentation method in severely resorbed maxillae.

193 The inferiority of the slow-resorbing membrane was evident by the extensive clinical

194 raacetic acid (EDTA), a chelating agent, can resorb mineral deposits, but the systemic delivery of ED

195 line, to differentiate into osteoclasts and resorb mineralized matrix in vitro.

196 o Slc4a2-deficient osteoclasts are unable to resorb mineralized tissue and cannot form an acidified,

197 because the interproximal bone heights were resorbed more adjacent to the wider defects during the p

198 Osteoclasts are bone-resorbing multinucleated cells that are derived from the

199 Bone-resorbing multinucleated osteoclasts that play a central

200 These cells form high numbers of bone-resorbing OCL when cultured using standard conditions fo

201 e immortalized OCL precursors that form bone-resorbing OCL with an efficiency that is 300-500 times g

202 on glass and in the sealing zone in actively resorbing OCLs on bone; 3) p130(Cas) and PYK2 form a sta

203 heir differentiation to multinucleated, bone-resorbing OCs (P < 0.00002) in a receptor activator of n

204 L immunostaining in vivo on VEC located near resorbing OCs in regions undergoing active bone turnover

205 ifferential transcriptomic profiling of bone-resorbing OCs versus nonresorbing MGCs to generate a lis

206 e Massospondylus carinatus embryos which get resorbed or shed before hatching, similar to those of ge

207 ronics, systems that disintegrate, dissolve, resorb, or sublime in a controlled manner after a well-d

208 x formation, the starter matrix is degraded, resorbed, or metabolized.

209 ary cell culture system (RCCS) enhanced bone resorbing osteoclast (OCL) differentiation.

210 affect both bone-forming osteoblast and bone-resorbing osteoclast cell activity.

211 been limited mainly to their effects on bone-resorbing osteoclast cells, with implications that some

212 wth/apoptosis, immune cell function and bone-resorbing osteoclast formation, the expression of TRAIL

213 Here we identify a non-bone-resorbing osteoclast subtype termed vessel-associated os

214 t an essential signaling complex in the bone-resorbing osteoclast, and, therefore, each is a candidat

215 ing of degraded collagen, as typified by the resorbing osteoclast, may provide the cell with a regula

216 ivator of NF-kappaB ligand), a critical bone resorbing osteoclastogenic factor, has an important role

217 Bone-resorbing osteoclasts (OCLs) were recently identified as

218 by the coupled actions of hematopoietic bone-resorbing osteoclasts (OCs) and mesenchymal bone-forming

219 Because bone-resorbing osteoclasts (OCs) are derived from the monocyt

220 d to bone and differentiate into active bone-resorbing osteoclasts (OCs), thus providing evidence tha

221 coordinated activity between actions of bone-resorbing osteoclasts and bone forming-osteoblasts.

222 alyze underlying cellular mechanisms in bone-resorbing osteoclasts and bone-forming osteoblasts in mi

223 reduced, respectively, the formation of bone-resorbing osteoclasts and bone-forming osteoblasts.

224 ed MSCs (ASCs) on in vitro formation of bone-resorbing osteoclasts and pathological bone loss in the

225 both osteoclast precursors and mature, bone-resorbing osteoclasts as shown by qRT-PCR and Western an

226 phatase (cyt-PTPe) supports adhesion of bone-resorbing osteoclasts by activating Src downstream of in

227 t fashion and suppressed development of bone-resorbing osteoclasts by downregulating NFATc1 through t

228 Differentiation of bone-resorbing osteoclasts from hematopoietic precursors depe

229 e, we report the stepwise generation of bone-resorbing osteoclasts from human embryonic and induced p

230 Bone-resorbing osteoclasts have been identified as important

231 and MMP-9 were found to be localized to bone-resorbing osteoclasts in human breast-to-bone metastases

232 io between bone-forming osteoblasts and bone-resorbing osteoclasts in part through the induction of o

233 Inhibition of the differentiation of bone-resorbing osteoclasts is an effective strategy for the t

234 ical conditions, the differentiation of bone-resorbing osteoclasts is delicately regulated by the bal

235 Matrix-producing osteoblasts and bone-resorbing osteoclasts maintain bone homeostasis.

236 ally important cell-surface proteins on bone-resorbing osteoclasts represents a promising approach fo

237 Bone-resorbing osteoclasts significantly contribute to osteop

238 Although the control of bone-resorbing osteoclasts through osteocyte-derived RANKL is

239 ing activity of V-ATPase, early responses of resorbing osteoclasts to inhibition of phosphatidylinosi

240 on between bone-forming osteoblasts and bone-resorbing osteoclasts to orchestrate balanced progenitor

241 , which is identified in the sealing ring of resorbing osteoclasts, also demonstrates colocalization

242 opose that they are not only sources of bone-resorbing osteoclasts, but also of immune cells that inf

243 Myeloid cells can differentiate into bone-resorbing osteoclasts, therefore, we hypothesized that o

244 aling and regulates actin remodeling in bone-resorbing osteoclasts.

245 ytes, macrophages, dendritic cells, and bone-resorbing osteoclasts.

246 ivities of bone-forming osteoblasts and bone-resorbing osteoclasts.

247 rophages, foreign body giant cells, and bone-resorbing osteoclasts.

248 nst myeloma, also block the activity of bone-resorbing osteoclasts.

249 major collagenolytic enzyme produced by bone-resorbing osteoclasts.

250 actions of bone-forming osteoblasts and bone-resorbing osteoclasts.

251 ination of bone-forming osteoblasts and bone-resorbing osteoclasts.

252 recruitment, formation, and activity of bone-resorbing osteoclasts.

253 ttle is known about Hdac3 activities in bone-resorbing osteoclasts.

254 s sort results from elevated numbers of bone-resorbing osteoclasts.

255 ent of the bone forming osteoblasts and bone-resorbing osteoclasts.

256 is the main adhesion-induced kinase in bone-resorbing osteoclasts.

257 ids required for protein prenylation in bone-resorbing osteoclasts.

258 cid phosphatase-positive multinucleated bone-resorbing osteoclasts.

259 ut interactions between tumor cells and bone-resorbing osteoclasts.

260 ivities of bone-forming osteoblasts and bone-resorbing osteoclasts.

261 a significant increase in the number of bone-resorbing osteoclasts.

262 S induces macrophage differentiation to bone-resorbing osteoclasts.

263 including bone forming osteoblasts and bone resorbing osteoclasts.

264 ivities of bone-forming osteoblasts and bone-resorbing osteoclasts.

265 tion of osteoclast precursors to mature bone-resorbing osteoclasts.

266 s-RIS, any osteocytic lacunae caused by bone-resorbing osteocytes cause the probe to fluoresce in viv

267 adial bone growth, increased numbers of bone-resorbing periosteal osteoclasts, and increased bone fra

268 thepsin K-positive DCs were observed in bone-resorbing pits.

269 as successfully captured by the filter until resorbed (range, 1-4 weeks).

270 option for vertical augmentation of severely resorbed ridges.

271 e viable in the pre-implantation period, but resorb shortly after implantation.

272 Also, both the total resorbed surface area and number of resorption pits form

273 t resorption was quantified by measuring the resorbed surface area of the calcium phosphate substrate

274 ally in the remodeling intestine but not the resorbing tail, and that c-Myc was induced by T3 prior t

275 the remodeling and growing body than in the resorbing tail.

276 d RXRbeta) are expressed ubiquitously in the resorbing tail.

277 easing the ability of alveolar epithelium to resorb the edema should lead to benefits for patients wi

278 Arf-null mice fail to resorb the hyaloid vasculature within the ocular vitreou

279 ess OC degradation enzymes but are unable to resorb the mineral matrix.

280 Osteoclasts resorb the mineralized matrices formed by chondrocytes o

281 When the gas bubble was fully resorbed the graft started to detach.

282 ere were multinucleated, TRAP-positive cells resorbing the hypertrophic cartilage matrix.

283 eek, osteoclast activity was responsible for resorbing the necrotic bone, which in turn stimulated th

284 n all, 46 of 50 cells regenerated, either by resorbing the remaining neurites and elaborating a new n

285 responsible for dissolving the notochord and resorbing the tail.

286 Furthermore, the mutants failed to resorb their flagella, an event that normally renders th

287 sease may guide management with novel fibril-resorbing therapies.

288 in the delayed response class is highest in resorbing tissues and higher in the tail than in the bod

289 ocyst, the central regions of which fuse and resorb to leave three fluid-filled canals.

290 DFDBA and MFDBA are resorbed very slowly and apparently do not contribute to

291 h all of the constituent materials naturally resorb via hydrolysis and/or metabolic action, eliminati

292 ed process in which calcium is deposited and resorbed via a multiple phase process.

293 al, as evidenced by their reduced ability to resorb whale dentin in vitro and the significant hypocal

294 odontitis, tooth-supporting alveolar bone is resorbed when there is an increased expression of the pr

295 They start resorbing when cells re-enter the cell cycle (S phase) a

296 Bovine nasal cartilage was stimulated to resorb with the addition of interleukin-1alpha (IL-1alph

297 ociated with a mild cardiac hypertrophy that resorbed with age.

298 eoconductive potential; and 4) HY appears to resorb within a 12-week healing interval in the absence

299 The "old" zooids and their organs are resorbed within 24-36 h (programmed cell removal).

300 my), the budectomized zooids were completely resorbed within 36-48 h following onset of programmed ce