ライフサイエンスコーパス: restless legs syndrome

1 N1) have not previously been associated with restless legs syndrome.

2 riants reveals putatively causative genes in restless legs syndrome.

3 burden of low-frequency and rare variants in restless legs syndrome.

4 ms associated with brain iron acquisition in restless legs syndrome.

5 n brain iron acquisition in individuals with restless legs syndrome.

6 cept for variants previously associated with restless legs syndrome.

7 in the epithelial cells of choroid plexus in restless legs syndrome.

8 or were upregulated in the choroid plexus in restless legs syndrome.

9 eurons contributes to the pathophysiology of restless legs syndrome.

10 sleep disorders center received diagnoses of restless legs syndrome.

11 istory are characteristic of childhood-onset restless legs syndrome.

12 ility, depression, difficulty concentrating, restless legs syndrome (32%-40%), pica (40%-50%), dyspne

13 the activity of this protein is decreased in restless legs syndrome; a finding similar to our earlier

14 or to natural menopause had a higher risk of restless legs syndrome after the index date compared wit

15 found between frequent insomnia symptoms and restless legs syndrome, aging, and cardiometabolic, beha

16 oophorectomy, there was an increased risk of restless legs syndrome among women without a benign ovar

17 We conclude that, in restless legs syndrome, an increased HCN current in moto

18 ls were isolated from the motor cortex of 11 restless legs syndrome and 14 control brains obtained at

19 entified and replicated 13 new risk loci for restless legs syndrome and confirmed the previously iden

20 small effects have been identified for both restless legs syndrome and narcolepsy with cataplexy.

21 and studied the genetic correlations between restless legs syndrome and traits of interest.

22 mptoms of iron deficiency (fatigue, pica, or restless legs syndrome) and should be considered for tho

23 on's disease, dystonia, Tourette's syndrome, restless legs syndrome, and akathisia, have traditionall

24 nized conditions (motor stereotypy disorder, restless legs syndrome, and infantile masturbation) as w

25 rcadian disorders, obstructive sleep apnoea, restless legs syndrome, and rapid eye movement (REM) sle

26 onia, chorea, tics, myoclonus, stereotypies, restless legs syndrome, and various other disorders with

27 particular circadian disorders, narcolepsy, restless-legs syndrome, and OSAS.

28 clinical characteristics of childhood-onset restless legs syndrome are described.

29 r, a significant percentage of patients with restless legs syndrome are responsive to intravenous iro

30 The responsible mechanisms of restless legs syndrome are still not known, although cur

31 Diagnosis of restless legs syndrome, as defined using Diagnostic and

32 id eye movement sleep behavior disorder, and restless legs syndrome, as well as circadian disorders,

33 [21.0%] vs 135 women [8.2%]; P < .001), and restless legs syndrome before the index date (32 women [

34 loss of iron regulatory protein activity in restless legs syndrome brain tissue further implicates t

35 derlying cause of the iron deficiency in the restless legs syndrome brain.

36 erlying the decreased iron concentrations in restless legs syndrome brains is unknown.

37 f relative brain iron deficiency reported in restless legs syndrome brains may underlie the problems

38 romelanin cells from the substantia nigra of restless legs syndrome brains.

39 ns in the iron management protein profile in restless legs syndrome compared with controls at the sit

40 on in the brain is lower in individuals with restless legs syndrome compared with neurologically norm

41 ng of the molecular mechanisms that underlie restless legs syndrome could lead to new treatment optio

42 This issue provides a clinical overview of restless legs syndrome, focusing on diagnosis, treatment

43 depression (g = 1.10, 95% CI [1.06, 1.15]), restless legs syndrome (g = 1.41, 95% CI [1.25, 1.56]),

44 medical condition, obstructive sleep apnea, restless legs syndrome, idiopathic insomnia, and circadi

45 For restless legs syndrome, implicated variants are typicall

46 including central sleep apnea, insomnia, and restless legs syndrome-in AF pathogenesis and progressio

47 navian cohorts and on other sleep disorders (restless legs syndrome, insomnia) and sleep traits (dura

48 e were performed on patients with idiopathic restless legs syndrome (iRLS) who were not currently on

49 Restless legs syndrome is a common neurologic disorder t

50 Restless legs syndrome is a curious neurological disorde

51 Restless legs syndrome is a frequent neurological disord

52 Restless legs syndrome is a neurological disorder charac

53 Restless legs syndrome is a prevalent chronic neurologic

54 Restless legs syndrome is a sensorimotor network disorde

55 EAP4, VAV3) resided in the vicinity of known restless legs syndrome loci, whereas 5 (BBS7, CADM1, CRE

56 ted odds ratio =1.26; 95% CI = 1.02-1.54) or restless legs syndrome (n = 108, adjusted odds ratio = 1

57 med as the strongest genetic risk factor for restless legs syndrome (odds ratio 1.92, 95% CI 1.85-1.9

58 (odds ratio [OR], 4.49; 95% CI, 3.98-5.06), restless legs syndrome (OR, 3.73; 95% CI, 3.39-4.09), bi

59 In addition, there were associations with restless legs syndrome (OR, 4.19; 95% CI, 3.91-4.50), sl

60 xt of another primary sleep disorder such as restless legs syndrome, or secondary to another underlyi

61 Restless legs syndrome (RLS) affects up to 10% of older

62 ies suggested a positive association between restless legs syndrome (RLS) and coronary heart disease

63 Most research on the association between restless legs syndrome (RLS) and depression has involved

64 Restless legs syndrome (RLS) and periodic limb movements

65 n the urge to move and sensory discomfort of restless legs syndrome (RLS) and properties of melanocor

66 minergic medications relieve symptoms of the restless legs syndrome (RLS) but have the potential to c

67 Restless legs syndrome (RLS) is a CNS disorder involving

68 Restless legs syndrome (RLS) is a common neurologic cond

69 Restless legs syndrome (RLS) is a common neurological di

70 Restless legs syndrome (RLS) is a common neurological di

71 Restless legs syndrome (RLS) is a common sensorimotor di

72 Although restless legs syndrome (RLS) is a disorder recognized in

73 Restless legs syndrome (RLS) is a frequent sleep-related

74 Restless legs syndrome (RLS) is a neurological condition

75 Restless legs syndrome (RLS) is responsive to opioid, do

76 revious cross-sectional study, we found that restless legs syndrome (RLS) was associated with erectil

77 isual perceptive computing (19 patients with restless legs syndrome (RLS), 21 patients with obstructi

78 Restless legs syndrome (RLS), also known as Willis-Ekbom

79 Restless Legs Syndrome (RLS), first chronicled by Willis

80 spinal cord is implicated in the etiology of Restless Legs Syndrome (RLS), which is more prevalent in

81 1 dopaminergic systems in the development of restless legs syndrome (RLS)-like movements during sleep

82 on deficiency (BID), a pathogenetic model of restless legs syndrome (RLS).

83 uding 46 drug-naive patients with idiopathic restless legs syndrome (RLS).

84 ief from dysaesthesias and motor symptoms in restless legs syndrome (RLS).

85 ales (p = 0.007), had a higher proportion of restless legs syndrome (RLS; p < 0.001), had a higher bo

86 value of sex, daytime somnolence, insomnia, restless legs syndrome, sleep apnoea, urinary dysfunctio

87 f sleep are imperfect and may be affected by restless legs syndrome, these findings provide new biolo

88 This cohort study found that risk of restless legs syndrome was increased among women who und

89 A family history of restless legs syndrome was present in 23 of 32 (72%) sub

90 in and its receptor in the microvessels from restless legs syndrome was significantly decreased compa

91 controls and 14 individuals who had primary restless legs syndrome was subjected to histochemical st

92 (parkinsonism, dystonia, tremor, chorea, and restless legs syndrome) were included.