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2 minutes (interquartile range, 97.7-162.0) in restricted visitation model to 245 minutes (interquartil
5 igh-affinity Gag293-specific TCRs were cross-restricted by up to 5 distinct HLA-DR alleles, accountin
6 past or current substance use disorder, and restricting duration to 7 days or less and using lower d
8 thyltransferase and Lon-mediated proteolysis restrict CcrM to a specific time in the cell cycle, ther
13 On present-day Earth, dust emissions are restricted only to a few desert regions mainly due to th
15 ites of neurons, enabling fast and spatially restricted responses to a dynamically changing extracell
16 ding areas decreased dramatically and cranes restricted their activity to a small partially unflooded
18 fter maturation of the blood-neural barrier, restricting homeostatic signaling to a subset of arterio
19 ents nuclear localization of beta-catenin by restricting its distribution to a discrete submembrane p
20 s were considered but the simple approach of restricting RACD to a 200-m radius maximized yield and e
21 reign PhDs from working in startups, thereby restricting startups' access to a large segment of the S
22 ifferentiation in vascular progenitors, thus restricting these cells to a vascular endothelial fate.
24 escribe a dual genetic strategy in mice that restricts reporter labelling to a subset of the most qui
27 n of convection in climate models has so far restricted our ability to accurately simulate African we
28 involves a mechanism of H(+) exchange, which restricts flux to acidic membranes such as synaptic vesi
29 ins are subject to lipid modification, often restricting them to act in a localized manner on respons
30 w that the conditional expression of Neurod1 restricts Neurog3+ progenitors to adopt Paneth cell fate
31 use of the lack of transgenic reporters that restrict Cre expression to adult cardiomyocytes that ree
34 truation, as well as an economic environment restricting access to affordable menstrual materials.
38 ntrate therapeutics within a unique, cardiac-restricted compartment to allow sustained drug penetrati
40 Fe(III), little is known about how the host restricts access to another biologically relevant oxidat
43 n distance and QRS morphological change when restricting pacing points to areas of voltage >0.5 mV.
52 the index date backwards by 2 years, and we restricted our analyses to cases and controls without a
54 enabling the critical dissection of H-2D(b)-restricted Ag presentation to CD8 T cells, revealing cel
57 d using intersectional genetic methods which restrict reporter expression to cells that co-express mu
59 or concurrently, and assessed the effect of restricting vaccination to certain months of the year.
60 means of controlling zoosporic diseases are restricted primarily to chemical treatments, which are u
61 and support recovery of function is severely restricted, contributing to chronic neurological deficit
62 2 maintains undifferentiated basal cells and restricts basal-to-ciliated differentiation, and we pres
65 anel of food and beverages brought home, and restricted our analyses to consumers who purchase bevera
66 hypoxia potentiates the pressor response and restricts blood flow to contracting muscles, this intera
68 S. institutions and clinicians may or should restrict patient access to COVID-19 drugs and vaccines t
69 able strategy for performing this task is to restrict integration to cues that coincide in space and
70 fic alphaMHC-MerDreMer-Ki67p-RoxedCre]) that restricts Cre expression to cycling adult cardiomyocytes
72 y the low number of high-quality studies and restricting our searches to databases that mainly indexe
73 r secondary aim was to model volume by using restricted cubic splines to determine the association be
74 he insoluble character of fibrin clots, have restricted our ability to develop novel treatments for c
75 rmations) have so far remained elusive, thus restricting efforts to develop antiviral treatments and
76 This TBEV-induced NK cell activation was restricted predominantly to differentiated CD57(+)CD56(d
78 atin is a specialized form of chromatin that restricts access to DNA and inhibits genetic processes,
79 ing H1's promotion of chromatin folding that restricts access to DNA methyltransferases responsible f
81 and later in adulthood unlock metabolically restricted epigenetic reprogramming to drive metabolic d
83 of clinically important antibiotics, greatly restricting the ability to effectively treat critically
84 , making this strategy suited for areas with restricted access to ELF and transient elastography or l
85 in TMEM43; and the patient's willingness to restrict exercise and to eliminate participation in comp
86 promoter CpG island hypermethylation is not restricted solely to emerging naive cells, suggesting th
88 ling this simple non-human leukocyte antigen-restricted approach to enhanced CAR-T functionality to b
91 sponding V558Delta;V653A Kit double mutation restricted (a) spatially to ETV1(+) cells, which include
92 ds model, in all participants and also after restricting the analysis to euthyroid participants (defi
93 ansgene optimization and increases safety by restricting escape concerns to experimentation windows.
94 mentation and limitations on narrative notes restricted clinicians' ability to express their clinical
95 port for parallel execution on clusters, and restricted flexibility to extend the underlying logic pr
96 mmunogenicity and low membrane permeability, restricting most therapies to extracellular targets and
97 ere compared with the status quo: scenario 1 restricted deliveries to facilities currently capable of
98 ed to provide caesarean sections; scenario 3 restricted delivery to facilities that provided five or
99 s regulated salesperson gifts to physicians, restricted salesperson access to facilities, and incorpo
100 s (scenario 2; 10.2-13.1), whereas scenarios restricting women to facilities that provided five or mo
102 methods address lethal means safety (such as restricting access to firearms, poisons, and medications
103 research shows that when children experience restricted access to food, they display increased intake
104 h rainfall (rain-on-snow) can cause 'icing', restricting access to forage, resulting in starvation, l
105 We randomly assigned these clusters using restricted randomisation to four groups: RACD only, rfMD
106 ge volumes at nanoscale resolution have thus restricted vertebrate studies to fragments of circuits.
111 d that the benefits of crowdsourcing are not restricted only to harnessing the time, labor, and funds
112 antigen-specific CD8 T cells are not class I restricted (referred to here as "unrestricted" or "atypi
114 of salient but irrelevant visual objects and restricts their access to higher stages of visual proces
115 nteresting new gene (RING)-type E3s, thereby restricting it to homologous to E6AP C-terminus (HECT) a
116 ]), Embase, and Adisearch/Odyssey databases, restricting our search to human studies published in Eng
117 e or a competing endogenous (ce)RNA for HuR, restricting its availability to HuR target mRNAs and the
118 and where inadequate diagnostic methods have restricted our ability to identify and control the disea
119 he importance of further evaluation of HLA-C-restricted responses to identify novel targets for HIV-1
120 of both sensitivity and spatial resolution, restricting the ability to identify different patterns o
124 ity following cochlear implantation has been restricted due to incompatibility between established ne
125 The association remained significant when we restricted our analysis to individuals of European ances
127 ere run across all participants and repeated restricting the sample to individuals with unimpaired co
128 ng to CAR T cells include severe toxicities, restricted trafficking to, infiltration into and activat
131 expression of Cyp1a1 throughout the body or restricted specifically to intestinal epithelial cells r
133 y metabolized and poorly membrane permeable, restricting its use to intratumoral administration.
135 ioned near the cupin dimerisation interface, restricting binding to just one CAL1 molecule per CENP-C
136 nutritional immunity - host processes which restrict microbial access to key micronutrients such as
138 ize of many sophisticated biologging devices restricts their application to larger animals, whereas o
139 postexposure prophylaxis (PEP) is expensive, restricting access to life-saving treatment, especially
140 ents are predominantly managed by methionine-restricted diet (MRD) to limit the production of Hcy.
141 to the ferroxidase center and acts as a flow-restricting valve to limit the activity of the ferroxida
144 aling that is not modulated by IL-2, thereby restricting responses to low-affinity or low-abundance s
145 onors after circulatory death (DCD) protocol restricts donor age to <55 years, no-flow time to <30 mi
148 tive capacity in tendon-derived fibroblasts, restricting their ability to maintain biosynthesis of te
149 g treatments for epilepsy attempt to broadly restrict excitability to mask a symptom, seizures, with
150 ance to many areas of biology and so here we restrict our focus to matters we think are of broadest i
152 astructural alterations were associated with restricted peritoneal susceptibility to metastatic colon
153 ntrol constrains retrieval processing and so restricts what comes to mind as input to the attribution
154 ppressor that inhibits cell proliferation by restricting entry to mitosis as well as protecting cells
155 hes to low-cost microscopy are fundamentally restricted, however, to modest field of view (FOV) and/o
157 ps through conformational stabilization that restricts access to N-linked glycosylation enzymes.
158 exponentially with the number of variables, restricting most searches to narrow areas of materials s
163 synapse formation, or by axon guidance cues restricting access to one of several acceptable targets.
164 me/nucleosome-depleted region structure that restricts HO activation to one of two paralogous DNA-bin
165 , particularly during early development, has restricted researchers to only scratching the surface of
168 cus from pregnant patients was significantly restricted compared to ovulating patients, but not signi
171 for selective absorption of nutrients, while restricting access to pathogens and food-borne antigens.
172 yed single peptide autoantigens, which would restrict ASI to patients expressing specific Human Leuko
173 atitis C virus (HCV) prompted many payers to restrict treatment to patients who met non-evidence-base
174 pain can have varying levels of severity, we restricted our analysis to patients with pain severe eno
177 iline available to all patients with MDR TB, restricting bedaquiline usage to patients with MDR plus
180 significantly improved post-LT outcomes when restricting LT to patients with a reduction in AFP from
181 he effects of age, sex and ethnicity or when restricting the analyses to patients who were both medic
184 HR 1.69; 95% CI 1.15-2.48; p=0.008) and when restricting the analysis to people aged <60 years (aHR 2
185 ructure-exhibits theta (4-7 Hz) oscillations restricted primarily to periods of active (REM) sleep.
187 signal-to-noise ratio, and the use of (11)C restricts its use to PET research centers and hospitals
188 as universal detectors for GC x GC has been restricted mainly due to physical limitations such as in
190 ion of the priming factor Munc13 exclusively restricted prefusion states to point contacts, all of wh
192 ging, and required either trio sequencing or restricting phasing to population-based haplotypes.
193 f DR circuitry require Cre-driver lines that restrict transgene expression to precisely defined cell
194 -VLBW subcohort also may reflect biases from restricting the cohort to prematurity, because prematuri
195 rial such as cuttings, seedlings or seeds is restricted in order to prevent its spread to disease-fre
196 een attributed to various factors, including restricted access to preventative and therapeutic health
197 peting endogenous noncoding RNA for miR-150, restricting its capability to promote cell growth and th
198 ied a metabolism-associated gene with highly restricted expression to PV(+) interneurons: Cox6a2, whi
200 nimize T-wave oversensing, and features that restrict therapy to regular rhythms in ventricular tachy
202 it is unclear how they generate a spatially restricted signal to repair the plasma membrane wound.
203 tions and find good agreement, so long as we restrict ourselves to 'resonant' encounters(10) (the rou
205 consumption rates) of aquatic organisms and restricts predictions to resting metabolism, which is le
206 ging, particularly if the material choice is restricted by roll-to-roll and benign solvent processing
210 entscher et al. engineered a skeletal muscle-restricted CHIKV to show that while musculoskeletal dise
211 omain A isoform (FnEDA), which is relatively restricted in distribution to sites of tissue injury.
213 ermaphrodite response to the male pheromone, restricting it to situations in which the presence of a
214 dy segments, suggesting that these genes may restrict PGC formation to specific abdominal segments in
215 use of a stratified block randomisation via restricted web platform to standard of care (control) or
216 utput in WF cells and local inhibition helps restrict responses to stimuli that are both small and mo
219 closely connected to leaf development, which restricts our ability to study the process of chloroplas
220 bleaching in STED/RESOLFT nanoscopy through restricting the scanning to subdiffraction-sized regions
221 cian education, media strategies, screening, restricting access to suicide means, treatments, and int
222 luding low depths of tissue penetration that restrict PDT to superficial lesions, inability to treat
223 can be controlled in prospective studies by restricting analyses to susceptible individuals with an
227 focused on exploiting their antigenicity and restricted expression pattern to target them with cancer
230 than conventional enrichment strategies that restrict enrollment according to the baseline risk of de
233 NCC and FANCE act as substrate receptors and restrict monoubiquitination to the FANCD2:FANCI heterodi
235 i(i) and i(k) alleles of the I locus, which restrict pigment to the hilum or saddle region of the se
237 for surveillance and monitoring systems; and restricted access to the medicines and diagnostics neces
238 activities are difficult to establish given restricted access to the region and persistent cloud cov
240 ermline, and, through TAS3-derived ta-siRNA, restricted ARF3 expression to the medio domain of ovule
241 howed magnetic resonance imaging (MRI) focal restricted diffusion confined to the left temporal and o
242 for developmental toxicity have been largely restricted due to the limited molecular data available f
244 , a hominoid-specific enzyme with relatively restricted expression to the brain, was critically invol
245 find greater accessibility in and near genes restricted in expression to the prosensory region of the
246 ght how this work is exposing the previously restricted intracellular space to the potential of thera
247 ever, high cost and technological complexity restricted its proliferation to the wider biological com
250 nger alcohol exposure (7 d x 2.5 g/kg, i.p.) restricted these increases to the dorsal striatum, and t
251 duced higher levels of IFN production, which restricted viral spread to the central nervous system.
252 at the VCBC complex is more conformationally restricted when bound to the antiviral APOBEC3F (one of
254 pression levels was found to be optimal when restricting analysis to the CD45RA(-)Foxp3(+) fraction.
256 plane using the temporal focusing method and restricting channelrhodopsin to the soma and proximal de
257 lar results were found in secondary analyses restricting comparisons to the cognitively unimpaired LL
258 may prevent spread of damage along the axon, restricting damage to the immediate vicinity of plaques.
262 rentiation into cardiomyocytes; in contrast, restricting Hdac3 to the nuclear periphery rescues myoge
265 rgetics, sustaining local tumor growth while restricting mitochondrial redistribution to the cortical
267 it's activity from its downstream targets by restricting this activity to the circuit's output-null n
273 cytoplasm and an apical cortical domain that restricts differentiation factors to the basal cortex.
274 ture of that conventional CEA culture system restricts its use to the treatment of critical and life-
276 on associated with the conformational change restricts lipid access to the nano-pocket, interrupting
277 the innate mechanisms by which the placenta restricts microbial access to the intrauterine compartme
279 e BCP as the organometallic component, which restricts scope due to the harsh conditions typically re
281 l applications of many anti-cancer drugs are restricted due to their hydrophobic nature, requiring us
283 Many policies, such as closing schools and restricting populations to their homes, impose large and
284 and fourth mesomeres, while ventral rays are restricted distal to these elements, suggesting the pres
285 thods are usually in transmission mode, thus restricting the use to thin and transmitting samples.
286 but since there is nothing in the mechanism restricting it to this metal, the oxide relay functional
287 TEC) and dendritic cells (DC) present tissue-restricted antigens (TRA) to thymocytes to induce centra
290 n depth analysis uncovered a projection type restricted almost exclusively to transcriptionally defin
292 e indicated losses of 30% from 1986 to 2014, restricting S. polyschides to upwelling regions at the s
293 r and assimilates in plants remains limited, restricting our ability to use delta(18) O as a tracer o
295 h Organization definition can be improved by restricting witnessed SCDs to ventricular tachycardia/fi
296 in the wild, efforts are still continuing to restrict the extent to which live virus is distributed i
297 ng this tool, we identified a unique H-2D(b)-restricted epitope to which there was a CD8(+) T cell re
298 tionary dynamics of the population play out, restricting the extent to which the evolved diversity of