ライフサイエンスコーパス: restrictive

1 rica (IDSA) criteria for OPAT in IE are very restrictive.

2 ncreased and access to tailored gRNAs is now restrictive.

3 but their limited packaging capacity can be restrictive.

4 e conditions for multilocus polymorphism are restrictive.

5 nontoxic to mammalian colon cells and is gut-restrictive.

6 A mixed persuasive-restrictive 4C antibiotic stewardship intervention was i

7 ignificantly higher in countries with highly restrictive abortion laws than in those with less restri

8 sults to employ the most efficient and least restrictive actions and interventions.

9 ning the regions within SERINC5 that provide restrictive activity or Nef sensitivity should inform me

10 Restrictive advice is unnecessary for NET patients being

11 teria have been relaxed, mainly through less restrictive age limits.

12 We also assessed a more restrictive algorithm (ie, assessing only children with

13 ologous strain of SIV in animals with TRIM5a restrictive alleles.

14 SIVsmE660 in animals that carried TRIM5alpha restrictive alleles.

15 s bronchiolitis obliterans syndrome (BOS) or restrictive allograft syndrome (RAS) is the major limiti

16 m bronchiolitis obliterans syndrome (BOS) or restrictive allograft syndrome (RAS) who underwent F-FDG

17 re assessed, and association between adrenal restrictive and adrenal permissive alleles and FEV(1)PP

18 However, enzymatic ligation is restrictive and current chemical ligation methods lack f

19 trict gluten-free diet; however, the diet is restrictive and gluten is difficult to avoid.

20 FFR were compared between restrictive and least-restrictive states during 3 period

21 assume linear effect of covariates, which is restrictive and may not be sufficient for certain phenot

22 ing adult lung function and influencing both restrictive and obstructive patterns.

23 However, conventional strategies are often restrictive and only focus on small regions of the antib

24 e current definition of high-risk profile is restrictive and oversimplified.

25 Here, we perform RNAseq on restrictive and permissive macrophages and reveal that t

26 athies have been discovered (arrhythmogenic, restrictive, and noncompacted) and added to update the W

27 ort that a subset of patients suffering from restrictive anorexia nervosa have enhanced habit formati

28 ation of a ubiquitin ligase to degrade virus-restrictive APOBEC3 enzymes.

29 data are insufficient to determine whether a restrictive approach to transfusion can be used without

30 series as a dynamical system suffer from too restrictive assumptions about the type of kinetics, or l

31 from parasite abundance data by (i) relaxing restrictive assumptions on the timing of host mortality

32 ing hypotheses to solve this problem require restrictive assumptions that may not be justified, such

33 eripheral nerve microvascular morphogenesis, restrictive barrier formation, influx and efflux transpo

34 y p120 is required for VE-Cad formation of a restrictive barrier, we restored VE-Cad levels using an

35 tion of the rigid lymphocyte nucleus through restrictive barriers.

36 nteraction, communication, and repetitive or restrictive behavior.

37 to deliver large biologics across the highly restrictive blood-brain barrier.

38 Crucially, our findings imply that restrictive border policy can increase exposure and vuln

39 State scorecards were obtained from firearm-restrictive (Brady Campaign/Law Center against Gun Viole

40 n disease and thus can be studied using less-restrictive BSL2 protocols.

41 Questionnaire (SCOFF), and categories of ED (restrictive, bulimic, hyperphagic, and other types of ED

42 tly of IFITM3 S-palmitoylation, indicating a restrictive capacity distinct from reported inhibition o

43 relaxation is a hallmark of hypertrophic and restrictive cardiomyopathies (HCM and RCM).

44 The restrictive cardiomyopathies are a heterogenous group of

45 LNC variants among patients with dilated and restrictive cardiomyopathies, pointed to this gene as an

46 Restrictive cardiomyopathy (RCM) is a rare cardiomyopath

47 Restrictive cardiomyopathy (RCM) is characterized by non

48 d cardiomyopathy (DCM, n=19 921), nonamyloid restrictive cardiomyopathy (RCM, n=248), or ACM (n=46) b

49 yloid deposition leads to an infiltrative or restrictive cardiomyopathy and is the major contributor

50 rwent cardiac transplantation as a result of restrictive cardiomyopathy caused by a heterozygous R406

51 myloid cardiomyopathy (ATTR-CM) results in a restrictive cardiomyopathy caused by extracellular depos

52 man sarcomeric mutation in MYL2 causative of restrictive cardiomyopathy in a mouse model.

53 Restrictive cardiomyopathy is a rare heart disease assoc

54 of RNAi therapeutics directed towards human restrictive cardiomyopathy.

55 to replicate efficiently or form plaques in restrictive cell types.

56 ender SV40 HR viruses unable to replicate in restrictive cell types.

57 hput shRNA library screen in IRF8 expression-restrictive cells enabled the identification of MafK as

58 s rarely formed viral replication centers in restrictive cells, a phenotype that could be rescued by

59 MafK-int6 binding region in IRF8 expression-restrictive cells.

60 viral reporter constructs in only expression-restrictive cells.

61 h-death models faced difficulties due to the restrictive choices of birth and death rate curves throu

62 lenges associated with establishing globally restrictive chromatin, we express histones in a naive sy

63 A restrictive cubic spline method was used to estimate the

64 Restrictive DAA access policies may decrease survival co

65 ction (DD), with 25% exhibiting grade III/IV restrictive DD with mitral regurgitation.

66 the consistency of our results using a more restrictive definition of multimorbidity including only

67 SDs, and stunting rates were found when less restrictive definitions of ideal environments were used.

68 and epileptogenesis, we generated mice with restrictive deletion of mTOR in microglia.

69 Restrictive dietary prescriptions that exclude animal pr

70 ic institution and included 15 patients with restrictive diplopia after pterygium excision.

71 Restrictive diplopia is a potential complication after p

72 plex I inhibition with rotenone mimicked the restrictive effects of CDK1 inhibition on mitochondrial

73 The restrictive effects of IFN-I require the interferon regu

74 etastases have been understudied, because of restrictive eligibility across all phases of clinical tr

75 Excessive or overly restrictive eligibility criteria can slow trial accrual,

76 prospective trials have indicated that less-restrictive, empiric, elimination diets can be effective

77 ons and thereby establish the characteristic restrictive endothelial barrier.

78 Restrictive entry and integration policies are linked to

79 Restrictive entry policies (eg, temporary visa status, d

80 re iron uptake clusters, reflecting the iron-restrictive environment in vivo.

81 ' decisions are subject to more negative and restrictive evaluations.

82 ly (hours/weeks/months) without the need for restrictive experimental control.

83 both proteins previously reported to act as restrictive factors for lytic cycle transcription and vi

84 preserved ejection fraction, particularly if restrictive features are present; unexplained hepatomega

85 associations from child body composition to restrictive feeding (e.g., for zBMI at 4 y: Bindirect =

86 Parental restrictive feeding (i.e., limiting food intake of child

87 There was no temporal association from restrictive feeding at age 4 y to child zBMI at age 10 y

88 Restrictive feeding practices are associated with increa

89 tment for baseline zBMI.The continued use of restrictive feeding practices at age 10 y appeared to be

90 At ages 4 and 10 y, restrictive feeding was assessed with the parent-reporte

91 ne the bidirectional association of maternal restrictive feeding with children's weight and body comp

92 uding serum starvation, serum variation, and restrictive feeding.

93 etabolic stress such as serum withdrawal and restrictive feeding.

94 Restrictive firearm legislation is associated with decre

95 stration protocols that include standardized restrictive fluid rates can potentially help to mitigate

96 ervosa (AN) engage in maladaptive behaviors (restrictive food choices and overexercising) that may or

97 mia nervosa, binge eating disorder, avoidant-restrictive food intake disorder, pica, and rumination d

98 IRF microscopy to simultaneously control the restrictive force against condensation and to visualise

99 mmes that promote gender equality and target restrictive gender norms among young people.

100 Restrictive gender norms and gender inequalities are rep

101 ction to systematically identify and address restrictive gender norms and gender inequalities in heal

102 Without addressing the role of restrictive gender norms and gender inequalities within

103 s that aimed to reduce gender inequality and restrictive gender norms and improve health.

104 athways, including how gender inequality and restrictive gender norms impact health through different

105 ubstantial impact of gender inequalities and restrictive gender norms on health risks and behaviours.

106 o decrease gender inequalities and transform restrictive gender norms to improve the health and wellb

107 the relationships between gender inequality, restrictive gender norms, and health and wellbeing.

108 GC patients homozygous for the adrenal restrictive genotype have lower FEV(1)PP compared with n

109 y confirmed: FEV(1)PP for homozygous adrenal restrictive genotype in GC vs. noGC is 49.8 vs. 63.4 (P

110 received more RBC units than patients in the restrictive group (1 [0-3] vs 0 [0-2] unit; p < 0.001).

111 ral group was lower (59% vs 70%) than in the restrictive group (hazard ratio, 0.72; 95% CI, 0.53-0.97

112 67 patients) versus 56% (84 patients) in the restrictive group (hazard ratio, 0.74; 95% CI, 0.53-1.04

113 30 days, there were 12 deaths (21.8%) in the restrictive group and 12 deaths (22.2%) in the usual car

114 2002-2017, 7,091 were from 24 states in the restrictive group and 3,745 from 14 states in the unrest

115 The restrictive group received fewer blood transfusions: mea

116 The restrictive group received significantly less resuscitat

117 We hypothesized that the restrictive group would have less blood stream infection

118 Infants who experienced restrictive growth conditions in utero and others expose

119 e associated with the implementation of more restrictive gun policies.

120 oint effects of these laws indicate that the restrictive gun policy regime (having a CAP law without

121 icenter trial block randomized patients to a restrictive (hemoglobin 7-8 g/dL) or liberal (hemoglobin

122 g HCT who were randomly assigned to either a restrictive (hemoglobin [Hb] threshold < 70 g/L) or libe

123 The adrenal restrictive HSD3B1(1245) genotype is associated with GC

124 The adrenal restrictive HSD3B1(1245A) allele limits conversion, wher

125 udes of association were more pronounced for restrictive impairment than for obstructive lung disease

126 Lung function revealed a mixed obstructive-restrictive impairment with reduced FEV1 and FVC in 75%

127 MID, Swedish, and Dutch guidelines were more restrictive in advising imaging, compared to the IDSA gu

128 They are restrictive in real application.

129 No other restrictive inclusion criteria were applied.

130 ilter gate that is coupled to an imperfectly restrictive internal gate, permitting the filter to samp

131 the causative agent of the diseases, through restrictive interventions, it is believed that only effe

132 ause Maximum Residue Level are becoming more restrictive, it is more important to consider the fruit

133 Patients were randomly assigned to a restrictive IV fluid resuscitation strategy (<= 60 mL/kg

134 These findings further support that a restrictive IV fluid strategy should be explored in a la

135 -) virus ultimately transitioned to the more restrictive latency I program, whereas cells infected wi

136 rized migration, many states have considered restrictive laws intended to make life so difficult for

137 ictive abortion laws than in those with less restrictive laws.

138 ata have remained hidden behind proprietary, restrictive licensing agreements, which raises barriers

139 e that either broader (recreational) or more restrictive (low-tetrahydrocannabinol) cannabis laws wer

140 ts Sinovenous outflow was significantly more restrictive (lower median CCS) in the hemorrhagic group

141 of HP before extensive pulmonary fibrosis or restrictive lung disease has occurred.

142 ibrosis in 8 of 10 patients (1.2% of the 760 restrictive lung disease patients transplanted in the sa

143 They suffered from restrictive lung disease requiring noninvasive mechanica

144 ctional abnormalities, such as emphysema and restrictive lung diseases, are frequently observed in pa

145 Severe LV dysfunction with a restrictive LV filling pattern was evident, which is ass

146 ncompacted-to-compacted ratio >=2.3), 3 more restrictive LVNC criteria were also evaluated (Jacquier,

147 Third, overlapped designations and less restrictive management appear to have adverse effects on

148 use of "immunity passports" as a way to ease restrictive measures and allow infected and recovered pe

149 Restrictive Medicaid policies are present in most states

150 al exogenous mitochondria and selection in a restrictive medium.

151 y reflect a pathology associated with a less restrictive microstructural environment such as decrease

152 impact of disease control without imposing a restrictive model.

153 rse graphs and (ii) the relaxation of common restrictive modeling assumptions.

154 ay be due to the use of limited gene panels, restrictive molecular matching algorithms, lack of drug

155 st exclusive use of a few animal models with restrictive monogenic backgrounds that may be more resis

156 increases VE-Cad levels and promotes a more restrictive monolayer.

157 eased, pointing to the development of a less restrictive movement pattern, and would support the latt

158 a or MCI were higher among participants with restrictive (multivariable-adjusted odds ratio, 1.58; 95

159 prepared a progressive series of torsionally restrictive N-substituted non-NIR fluorescent rosol dyes

160 re randomly assigned to liberal (n = 492) or restrictive (n = 521) red blood cell transfusion thresho

161 enter against Gun Violence [BC/LC]) and less-restrictive (National Rifle Association) groups.

162 he brain can oftentimes be attributed to the restrictive nature of the brain microvascular endothelia

163 ltivitamin/mineral supplements), despite the restrictive nature of the diet.

164 the different interventions, the potentially restrictive nature of the FFVs, not being able to measur

165 The restrictive nature of the GFD makes adherence a challeng

166 que structure of the lymphatics and the size-restrictive nature of the lymph node reticular network,

167 e is easy to prepare, disposable, within non-restrictive nature, which allows an approach of a new de

168 However, restrictive new immigration policies in the US have left

169 rophic cardiomyopathies are the most common; restrictive, noncompaction, and mixed cardiomyopathies o

170 Evidence that gender inequalities and restrictive norms adversely affect health is extensive;

171 genomic integration or the need to cross the restrictive nuclear barrier.

172 cted participants could indicate HIV-related restrictive or fibrotic pulmonary changes.

173 Subjects with restrictive or obstructive spirometry pattern at baselin

174 ntal, or metabolic insults can induce overly restrictive or overly permissive epigenetic landscapes t

175 articipants) were classified as obstructive, restrictive, or normal, and reversibility was determined

176 How this globally restrictive organization emerged during evolution remain

177 covery is uniquely difficult due to a highly restrictive penetration barrier and other mechanisms tha

178 Restrictive perioperative transfusion practices are a po

179 These microorganisms have a highly restrictive permeability barrier, which limits the penet

180 As hepcidin is central to the iron-restrictive phenotype in ACD, therapeutic approaches tar

181 e, a contraindication to anticoagulation, or restrictive physiology; (2) with severe biventricular dy

182 ibing: prospective audit-and-feedback (PAF), restrictive policies (RP), and no strategy.

183 ibing: prospective audit and feedback (PAF), restrictive policies (RP), and no strategy.

184 In the integration phase, restrictive policies in general, and specifically regard

185 002-2011 versus 2012-2017, evaluated whether restrictive policies were associated with decreased prop

186 compared for schools with or without peanut-restrictive policies.

187 ive force that enables their passage through restrictive pores in complex three-dimensional environme

188 and aggression in mental health settings yet restrictive practices continue to be frequently used.

189 ntions seeking to reduce violence and use of restrictive practices through enhanced de-escalation tec

190 etween these and increased aggression/use of restrictive practices.

191 n a host antiviral protein could enhance its restrictive properties.

192 ipheral endothelial cells, that maintain the restrictive quality of the BBB.

193 Patients were allocated to either a restrictive (R-group) or a standard (S-group) iv-fluid r

194 In patients undergoing HCT, the use of a restrictive RBC transfusion strategy threshold of 70 g/L

195 categorized Medicaid policies for states as "restrictive" (requiring documentation of a specific abst

196 all adult height and weight and mild chronic restrictive respiratory failure.

197 oosing a class is either too flexible or too restrictive results in poor genotyping performance.

198 09 patients, of whom 55 were assigned to the restrictive resuscitation group and 54 to the usual care

199 This pilot study demonstrates that a restrictive resuscitation strategy can successfully redu

200 Nod1 may exert its restrictive role by altering macrophage polarization, le

201 that willingness would be higher under more restrictive scenarios.

202 rics decreased as a function of increasingly restrictive scheduling scenarios, with the greatest cont

203 A restrictive selection strategy for cholecystectomy saves

204 A restrictive selection strategy for surgery in patients w

205 ed macular degeneration (AMD) are based on a restrictive set of risk factors.

206 the master transcriptional regulator, neuron restrictive silencer factor (NRSF), and its downstream t

207 ID1A, which can interact with a known neural restrictive silencer factor REST/NRSF.

208 F (RE1-silencing transcription factor/neuron-restrictive silencer factor) protein, a neuronal gene tr

209 ilencing transcription (also known as neuron-restrictive silencer factor) to position 509 of the KCC2

210 ment-1 silencing transcription factor/neuron restrictive silencing factor (NRSF).

211 mal spirometric pattern vs. 6.5% with a mild restrictive spirometric pattern [60 <= forced vital capa

212 edicted] vs. 21.2% with a moderate-to-severe restrictive spirometric pattern [FVC < 60% predicted], P

213 e of PPCs increased across the categories of restrictive spirometric pattern severity (6.0% with a no

214 (P for trend = 0.001) was higher across the restrictive spirometric pattern severity.

215 Patients with a moderate-to-severe restrictive spirometric pattern should be regarded as hi

216 able-adjusted analyses, a moderate-to-severe restrictive spirometric pattern was associated with a hi

217 The occurrence of PPCs in patients with a restrictive spirometric pattern was higher than that in

218 The incidence of PPCs in patients with a restrictive spirometric pattern was higher than that in

219 cohort study of 681 adults with a normal or restrictive spirometric pattern who were referred for pr

220 a substantial population of patients with a restrictive spirometric pattern, few studies have evalua

221 cially in patients with a moderate-to-severe restrictive spirometric pattern.

222 e at least 2-3 times/week for >=1 hour) with restrictive spirometry pattern at follow-up (defined as

223 al activity were at lower risk of developing restrictive spirometry pattern over 10 years.

224 ollow-up, 3.3% of participants had developed restrictive spirometry pattern.

225 gular physical activity and the incidence of restrictive spirometry pattern.

226 nd adult suicide, White and overall FFR than restrictive states (all P < 0.05).

227 were compared between restrictive and least-restrictive states during 3 periods (1999-2003, 2004-200

228 Within each period, least-restrictive states had greater unintentional, pediatric,

229 erygium excision, awareness of postoperative restrictive strabismus and the potential for correction

230 Although restrictive strategies are generally supported in hemato

231 A restrictive strategy (hemoglobin < 7 g/dL) is recommende

232 l (hemoglobin threshold, < 9 g/dL) or to the restrictive strategy (hemoglobin threshold, < 7 g/dL) of

233 Although the restrictive strategy did not decrease BSI, mortality, or

234 To assess whether a restrictive strategy of RBC transfusion reduces 28-day m

235 o were at moderate-to-high risk for death, a restrictive strategy regarding red-cell transfusion was

236 Overall, the restrictive strategy saved &OV0556;4563 from a societal

237 The restrictive strategy significantly reduced the cholecyst

238 2 months, 56.2% of patients was pain-free in restrictive strategy versus 59.8% after usual care.

239 The cost-effectiveness plane showed that restrictive strategy was cost saving in 89.1%, but resul

240 Restrictive strategy was economically evaluated against

241 patient, the lower the probability that the restrictive strategy will be cost-effective.

242 e-transfusion Hb levels were 70.9 g/L in the restrictive-strategy group and 84.6 g/L in the liberal-s

243 fusion type and baseline FACT-BMT score, the restrictive-strategy group had a higher FACT-BMT score a

244 ber of RBC units transfused was lower in the restrictive-strategy group than in the liberal-strategy

245 00 patients were randomly assigned to either restrictive-strategy or liberal-strategy treatment group

246 Future studies should explore whether restrictive surgery results in better perinatal outcomes

247 ultured organoids, removing the need for the restrictive synthetic semipermeable membranes that are r

248 calization and cell morphologies seen at the restrictive temperature in the myo2 smy1 mutant.

249 of a temperature-sensitive ACA mutant at the restrictive temperature prevented c-di-GMP-induced cAMP

250 issive temperature and a secretory defect at restrictive temperature.

251 inability of myo2-E1 to form colonies at the restrictive temperature.

252 isdictions (e.g. states, provinces) are more restrictive than others, and prevent Nurse Practitioners

253 ndomized noninferiority trial, we compared a restrictive threshold for red blood cell transfusion (tr

254 A slightly higher restrictive threshold is recommended in cardiac surgery

255 KD, AKI occurred in 33.6% of patients in the restrictive-threshold group (258 of 767) and in 32.5% of

256 AKI occurred in 27.7% of patients in the restrictive-threshold group (624 of 2251) and in 27.9% o

257 Patients in the restrictive-threshold group received significantly fewer

258 ome occurred in 11.4% of the patients in the restrictive-threshold group, as compared with 12.5% of t

259 ion occurred in 52.3% of the patients in the restrictive-threshold group, as compared with 72.6% of t

260 In the liberal vs restrictive thresholds groups, necrotizing enterocolitis

261 .2% to 1.5%; P = .37), in the liberal vs the restrictive thresholds groups, respectively.

262 Among infants in the liberal vs restrictive thresholds groups, the primary outcome occur

263 Our objective was to compare outcomes of a restrictive to a liberal red cell transfusion strategy i

264 cleosomal density of viral genomes, which is restrictive to viral gene expression and which E1A overc

265 and crumbs2b (crb2b) apical polarity genes' restrictive transcription in the red, green, and blue (R

266 Among patients undergoing cardiac surgery, a restrictive transfusion approach resulted in fewer red b

267 ber of RBC units transfused was lower in the restrictive transfusion group than in the liberal transf

268 ts support more widespread implementation of restrictive transfusion policies for adults with acute u

269 range of hemoglobin values and suggests that restrictive transfusion practices may not be appropriate

270 s the outcome and admission to an ICU with a restrictive transfusion protocol as the exposure of inte

271 30%), and mild (hematocrit, > 30%) anemia in restrictive transfusion protocol ICUs was 67%, 19%, and

272 ,510 patients (41.6%) were in an ICU with an restrictive transfusion protocol.

273 0%, 14%, and 2% for those in ICUs without an restrictive transfusion protocol.

274 Of the 59 study ICUs, 24 had an restrictive transfusion protocol; 2,510 patients (41.6%)

275 Adjusting for confounding factors, restrictive transfusion protocols independently reduced

276 modeling assessed the independent effects of restrictive transfusion protocols on transfusions.

277 Restrictive transfusion should be used cautiously after

278 The current literature supports the use of restrictive transfusion strategies in the majority of cr

279 lity and readmission rates suggest that less restrictive transfusion strategies might improve outcome

280 clinical research evidence supports using a restrictive transfusion strategy (e.g., hemoglobin thres

281 andomized to the liberal (n = 149) or to the restrictive transfusion strategy (n = 151) group.

282 A restrictive transfusion strategy halved blood product ut

283 Among infants in the liberal vs restrictive transfusion thresholds groups, respectively,

284 ed higher rates of cognitive impairment with restrictive transfusion thresholds.

285 Restrictive transfusion was associated with lower risk o

286 of liberal blood transfusions compared with restrictive transfusions did not reduce the likelihood o

287 roportion of patients receiving PRBC using a restrictive trigger hemoglobin concentration (trigger <7

288 nt SIVsmE660 variants in rhesus monkeys with restrictive TRIM5alpha alleles.

289 he mechanisms that drive the immunologically restrictive tumor microenvironment remain poorly underst

290 t efficacy in solid tumors can be limited by restrictive tumor microenvironments (TMEs).

291 ion due to abortion has been used to justify restrictive US abortion policies.

292 is strongly suspected because of the highly restrictive usage of 2 lambda variable (V) domains (IGLV

293 is not supported by the evidence and that a restrictive vegan diet decreases nutritional flexibility

294 ciated with abnormal PASP and PAC, whereas a restrictive ventilatory deficit was associated with abno

295 ere was no 30-day mortality difference: 9.5% restrictive versus 8.5% liberal (P = 0.892, chi test).

296 The effect of a restrictive versus liberal red-cell transfusion strategy

297 ence interval) of LTs paid by Medicaid among restrictive versus unrestrictive states between 2002 and

298 or any difference by prevalence of ALD among restrictive versus unrestrictive states.

299 In difference-of-differences analysis, restrictive (versus unrestrictive) policies were associa

300 iferative phase in the ectocervix, (iii) HIV restrictive Wnt/beta-catenin signaling pathway negativel