ライフサイエンスコーパス: retardation

1 dia, genitourinary malformations, and mental retardation).

2 , lipodystrophy, hepatosteatosis, and growth retardation.

3 of the 5 patients also had postnatal growth retardation.

4 us human disorders, such as perinatal growth retardation.

5 udley syndrome, characterized by psychomotor retardation.

6 phism, cardiac defects, and postnatal growth retardation.

7 symptoms of reduced motivation and/or motor retardation.

8 e related to symptoms of anhedonia and motor retardation.

9 lead to important, sometimes lethal, growth retardation.

10 to cerebral palsy, hydrocephalus, and mental retardation.

11 esented with epilepsy and severe psychomotor retardation.

12 zed for generalized seizures and psychomotor retardation.

13 umulation in rcy1Delta cells leads to growth retardation.

14 ch manifests as joint deformities and growth retardation.

15 a, hypotonia, oculomotor apraxia, and mental retardation.

16 alth effects, including cretinism and growth retardation.

17 ing animals exhibiting a lifelong 20% growth retardation.

18 ult in Phenylketonuria, a progressive mental retardation.

19 etinal dysplasia, microcephaly and/or mental retardation.

20 bination PIT showed significant tumor growth retardation.

21 impairment, including ataxia and psychomotor retardation.

22 he mutation causes dominant postnatal growth retardation.

23 ylase associated with human syndromic mental retardation.

24 Silencing of fragile X mental retardation 1 (FMR1) gene and loss of fragile X mental r

25 ansion in the 5'-UTR of the fragile X mental retardation 1 (FMR1) gene is known as a premutation.

26 es disrupted by loss of the Fragile X Mental Retardation 1 (Fmr1) gene.

27 (55-200 CGG repeats) of the fragile X mental retardation 1 (FMR1) gene.

28 (PNs) in the cerebellum of Fragile X Mental Retardation 1 (Fmr1) knockout (KO) mice, a model of Frag

29 l tissue from wide type and fragile X mental retardation 1 (Fmr1) knockout mice, we show that variabl

30 dritic spine defects of the Fragile X Mental Retardation 1 gene KO neurons.

31 Finally, upregulating fragile X mental retardation 1 protein (Fmr1, also called FMRP) acts inde

32 analysis converged on FMR1 (Fragile X Mental Retardation 1), an important negative regulator of APP t

33 complex subunit cytoplasmic fragile X mental retardation 1-interacting protein 1 (Cyfip1).

34 silencing of the X-linked, fragile-X mental retardation-1 (FMR1) gene.

35 rotein-like 2 (Cntnap2)(5), fragile X mental retardation-1 (Fmr1)(6) or Sh3 and multiple ankyrin repe

36 mpairment might have resulted in less growth retardation after pediatric kidney transplantation (KT)

37 on of ANAC017 in Arabidopsis leads to growth retardation, altered leaf development with decreased cel

38 ith pathogenic BCS1L variants include growth retardation, aminoaciduria, cholestasis, iron overload,

39 eads to increased R-loop levels, cell growth retardation and accumulation of gammaH2AX, a marker for

40 in the most common inherited form of mental retardation and autism, fragile X syndrome (FXS).

41 inked hypophosphatemia (XLH) leads to growth retardation and bone deformities, which are not fully av

42 cterized by severe pre- and postnatal growth retardation and by mutually exclusive mutations in three

43 Given that Cullin4B mutations cause mental retardation and cerebral malformation, similar regulator

44 N cause infantile hypotonia with psychomotor retardation and characteristic facies (IHPRF).

45 (CMV) infection is a leading cause of mental retardation and deafness in newborns.

46 l CMV infection is a leading cause of mental retardation and deafness in newborns.

47 We showed that local retardation and degree of polarization provide a robust

48 tch dysregulation are associated with mental retardation and dementia are poorly understood.

49 erm delivery, low birth weight, fetal growth retardation and developmental defects.

50 oxidative stress can ultimately cause growth retardation and developmental defects.

51 f NAA50 expression resulted in severe growth retardation and infertility in two Arabidopsis transfer

52 neurological disorder associated with mental retardation and intractable epilepsy, and Miller-Dieker

53 ven vascular storm included placental growth retardation and intrauterine growth restriction, evidenc

54 luding methylmalonic acidemia, severe growth retardation and lethality.

55 Conversely, ageing retardation and lifespan extension were achieved in mid-

56 sensitive to salinity stress causing growth retardation and loss in productivity.

57 ed with normal skin with heterogeneous local retardation and low degree of polarization, HTS was char

58 cursor cells (OPC) in mice results in growth retardation and markedly decreased bone mass with impair

59 ml CA-4 treatments resulted in developmental retardation and morphological malformation, and led to p

60 H supplementation was able to correct growth retardation and muscle weakness.

61 nflammatory phenotype associated with growth retardation and paw swelling.

62 disorder characterized by severe neuromotor retardation and progressive loss of vision, leading to b

63 Using gel-retardation and RNA/DNA competition assays, we found tha

64 , and correlated with the severity of growth retardation and the in vitro cellular phenotype.

65 the most prevalent form of inherited mental retardation and the primary monogenetic cause of autism.

66 logical disorders, including X-linked mental retardation and tumorigenesis.

67 elopment (collectively abbreviated as mental retardation and/or disorders of psychological developmen

68 se of the heart and the renal tract), growth retardation, and a recognizable facial gestalt (interrup

69 rial biosynthesis and clearance, cell growth retardation, and cellular senescence of DC fibroblasts.

70 xclusion criteria included amblyopia, mental retardation, and concomitant ocular disease that limited

71 two siblings with congenital ataxia, mental retardation, and developmental delay.

72 rological disorder cerebellar ataxia, mental retardation, and disequilibrium (CAMRQ) syndrome, strong

73 rological disorder cerebellar ataxia, mental retardation, and disequilibrium (CAMRQ) syndrome.

74 eviously linked to cerebellar ataxia, mental retardation, and disequilibrium syndrome 2, cause severe

75 sk of status dystonicus, intrauterine growth retardation, and endocrinopathies.

76 ional symptoms, such as anergia, psychomotor retardation, and fatigue.

77 orm of mild syndromic ID with ptosis, growth retardation, and hypotonia, and we identified an inherit

78 isorders are macrocephaly, absence of growth retardation, and more variability in the degree of intel

79 d our understanding of diet-dependent growth retardation, and offers a potential mechanism to treat o

80 seizures, one subject exhibiting mild mental retardation, and one subject exhibiting retinitis pigmen

81 aphy background, developmental regression or retardation, and onset before 1 year of age.

82 l response, poor treatment adherence, growth retardation, and presentation in advanced phases).

83 ess, onychodystrophy, osteodystrophy, mental retardation, and seizures), a condition that includes se

84 dly amenable to experimental acceleration or retardation, and serves as a constitutional component fo

85 tion, results in increased apoptosis, growth retardation, and, ultimately, embryonic death.

86 re promising candidates for integrated phase retardation applications due to their large optical bire

87 ystals are inherently inadequate for optical retardation applications since the supported polaritonic

88 range of values reported for hydration water retardation as a logical consequence of the different le

89 Using gel banding and retardation as a read-out for protein adsorption, we opt

90 reated promptly in infancy, can cause mental retardation, as the TH decrease results in improper deve

91 with bulkier thiolates causing dramatic rate retardations, as well as (2) the thermodynamics of the s

92 ng factors, in vitro transcriptional and gel retardation assays revealed that the RpoN-recognized P2

93 Only a few genetic studies of growth retardation associated with the KBD have been carried ou

94 are specifically linked to epilepsy, mental retardation, autism, schizophrenia and neuro-degeneratio

95 The RNA-binding protein fragile-X mental retardation autosomal 1 (FXR1) is upregulated in head an

96 expression levels of FXR1 (fragile X mental retardation autosomal homolog 1), an RNA-binding protein

97 Fragile-X mental retardation autosomal homologue-1 (FXR1) is a muscle-enr

98 display partial embryonic lethality, growth retardation, brain disorders, and maternal effect lethal

99 s, all of whom displayed intrauterine growth retardation, chronic neutropenia, and NK cell deficiency

100 derlies intra-uterine (and postnatal) growth retardation, chronic neutropenia, and NK cell deficiency

101 d to calculate first-order removal rates and retardation coefficients via a one-dimensional reactive

102 ionizing radiation, microcephaly, and growth retardation comparable to mutations in LIG4 and XRCC4, w

103 ne-treated groups showing significant myopic retardation compared to the control group.

104 pH, but exhibit increased mortality, growth retardation, corneal edema, and tooth enamel defects.

105 Significant cell growth retardation could be observed for pathogenic bacteria (e

106 ), craniometaphyseal dysplasia (CMD), mental retardation, deafness and ankylosis syndrome (MRDA).

107 hat loss of Ube3b in mice resulted in growth retardation, decreased grip strength, and loss of vocali

108 ckout of p21 can partially rescue the growth retardation defect of Ola1(-/-) embryos but fails to res

109 reductively retarded at Hanford site with a retardation degree dependent on reactive Fe(II) content

110 e overexpression are thought to cause mental retardation, dementia and seizure in this disorder.

111 xhibit a similar pattern of Fe(II) oxidation retardation derived from elevated silicate concentration

112 e with a syndromic disorder marked by growth retardation, diabetes, premature death, and severe lymph

113 s observed in ACH patients, including growth retardation, disproportionate shortening of the limbs, r

114 Severe growth retardation, distorted branches and up-curled leaves wer

115 pmental delay/intellectual disability/mental retardation, Down syndrome, cerebral palsy, autism spect

116 The ABI3p:OXA2a plants displayed growth retardation due to a reduction in the steady-state abund

117 -complemented plants displayed severe growth retardation due to a strong reduction in the steady-stat

118 smoke exposure results in fetal lung growth retardation due to dysregulation in various signaling pa

119 therapeutic approach to intrauterine growth retardation due to placental vascular hypofunction.

120 l (CSCF) syndrome is characterized by growth retardation, dysmorphic facial features, brachydactyly w

121 a rare Mendelian phenotype comprising severe retardation, early onset epileptic seizures, optic nerve

122 ability and luminous efficiency based on its retardation effect in reorientation.

123 EEG response, however, when tilted such that retardation effects are operative, the sEEG signal emerg

124 l response of metal nanoparticles, including retardation effects, without the requirement of large co

125 ipid nanostructures possessed superior tumor retardation effects.

126 rientations are also investigated to explore retardation effects.

127 MEDNIK syndrome (mental retardation, enteropathy, deafness, peripheral neuropath

128 ers including male infertility, early growth retardation, excessive weight gain in adulthood, heterot

129 easurement of Orbitrap and comparison of the retardation factors with standards.

130 y ID, ASD, microcephaly, intrauterine growth retardation, febrile seizures in infancy, impaired speec

131 obalamin may be associated with fetal growth retardation, fetal insulin resistance, and excess adipos

132 f 55-200 CGG repeats in the Fragile X mental retardation (FMR1) gene.

133 ettl14 leads to conspicuous embryonic growth retardation from embryonic d 6.5, mainly as a result of

134 ions of flow field profiles and hydrodynamic retardation functions.

135 grees of neurodevelopmental delay and growth retardation harboring one of 13 heterozygous variants in

136 lt in permanent neurological defects, mental retardation, hearing loss, visual impairment, and pregna

137 a regulatory loop with the fragile X mental retardation homologue FXR1 and regulates dopamine D2 rec

138 cal and neurologic anomalies, such as growth retardation; hypoplastic jaws crowded with multiple supe

139 nockout (Smad1/5(dKO)) mice displayed growth retardation, hypothyroidism and defective follicular arc

140 sorder that leads to brain damage and mental retardation if untreated.

141 cle arrest at the G1 phase and causes growth retardation in a panel of prostate cancer cells.

142 velength and maintain the quarter-wave phase retardation in broadband, while the turbine blades consi

143 ransporter 8 (MCT8) cause severe psychomotor retardation in children.

144 ssive disorder that results in severe mental retardation in early adulthood.

145 19) cause female-limited epilepsy and mental retardation in humans.

146 ecular pathomechanism of epilepsy and mental retardation in humans.

147 b locus associate with depression and mental retardation in humans.

148 tal ovine pancreatic islets, and that growth retardation in hypothyroid fetal sheep is associated wit

149 Growth retardation in recombinant PEDV carrying uncleavable N s

150 urrently in countries such as Brazil) due to retardation in solute flow associated with the fine root

151 suggesting that ABA is implicated in growth retardation in such nutritional stress.

152 Retardation in the degraded chain is given by a simple s

153 , knocking out EVI and MDS/EVI causes severe retardation in the growth and development of the tadpole

154 T12 harboring uncleavable N displayed growth retardation in Vero E6-APN cells compared to the wild-ty

155 dividuals were at risk of progressive growth retardation independent from the underlying disease and

156 ndividuals with severe prenatal-onset growth retardation, intellectual disability, and muscular hypot

157 g to directly measure the birefringent phase retardation introduced by metasurface wave plates with a

158 edium whereas inside neuronal dendrites this retardation is 70%.

159 Growth retardation is a major adverse long-term outcome among B

160 ral cortex, an important target since mental retardation is an important component of many of the hum

161 mulations of model peptides suggest that the retardation is due to an underlying general physicochemi

162 ater dynamics, whereas protein-induced water retardation is weaker and dominates only at distances be

163 S), the most common form of inherited mental retardation, is caused by silencing of the FMR1 gene.

164 systemic neuromuscular phenotype with mental retardation, leading to premature death at age 36 years

165 ental delay, intellectual disability, growth retardation, microcephaly, and variable craniofacial dys

166 posure causes craniofacial anomalies, growth retardation, neurological abnormalities, cognitive impai

167 ulin resistance, severe diabetes, and growth retardation observed in mice carrying N-ethyl-N-nitrosou

168 to damage, thus explaining the marked growth retardation observed in these conditions.

169 With mutation and selection, retardation occurs only when S, the product of twice the

170 We proceed to show that growth retardation occurs through the induction of transcriptio

171 characterized by metabolic acidosis, growth retardation, ocular abnormalities, and often dental abno

172 ad, which could be principally attributed to retardation of amylopectin retrogradation in the presenc

173 o mechanisms of glass formation: (i) kinetic retardation of atom rearrangement or structural relaxati

174 ons of 3D-spheroid size and shape as well as retardation of cell cycle and induction of apoptosis hav

175 Retardation of diclofenac was reflected in additional (1

176 mechanisms of resistance within a biofilm is retardation of drug diffusion due to poor penetration ac

177 ength of interaction), which originates from retardation of electromagnetic waves at the distances co

178 rom light-induced damage despite significant retardation of FTY720 phosphorylation in Sphk2 KO mice.

179 Weak coupling resulted in retardation of growth and differentiation.

180 ar catabolic routes were supported by severe retardation of growth of the DeltandbC mutant under ligh

181 rticipants; however, improvement in GA area, retardation of growth, or visual acuity were not demonst

182 eye, Heart defects, Atresia of the choanae, Retardation of growth/development, Genital abnormalities

183 This phenotype was due to the retardation of LRP emergence.

184 rsible sorption processes led to substantial retardation of many TrOCs along the investigated hyporhe

185 ex3 prostates, there was an ERbeta-dependent retardation of migration of activator protein-1 response

186 ss, indicated by increased origin firing and retardation of replication fork progression.

187 ly impairing CUL4, DDB1 or DET1 results in a retardation of SlGLK2 degradation by the 26S proteasome.

188 t, the magnitude of the toxin-induced growth retardation of target cells only weakly impacts the comp

189 underlying both joint destruction and growth retardation of the KBD.

190 tral locus (associative overdominance) and a retardation of the rate of loss of variability by geneti

191 We show that retardation of water motions near phospholipid bilayers

192 lyphenols may present a dietary route to the retardation or amelioration of neurodegenerative-related

193 en a diagnosis of mild or unspecified mental retardation or disorders of psychological and motor deve

194 rolled dimerization, which results in either retardation or enhancement of the transport of a reporte

195 ia accompanied by either intrauterine growth retardation or neutropenia.

196 f neurologic diseases associated with mental retardation or/and dementia.

197 ase content/activity, and displayed a growth retardation phenotype similar to that of the ndufs4 muta

198 me proteins cause microcephaly and/or growth retardation, phenotypes that are strongly linked to cent

199 brain development, the ZIKV-mediated growth retardation potentially contributes to the neurodevelopm

200 ancy are associated with intrauterine growth retardation, preterm birth, and fetal demise through mec

201 ted the RNA-binding protein fragile X mental retardation protein (encoded by Fmr1), which constrains

202 -dependent interaction with fragile X mental retardation protein (FMRP) and bind to one another's mRN

203 associated with the loss of fragile X mental retardation protein (FMRP) and haploinsufficiency of syn

204 lity was reduced by loss of fragile X mental retardation protein (FMRP) and that FMRP acts on BK chan

205 binding proteins including Fragile X mental retardation protein (FMRP) and the related protein FXR2P

206 ncoding the mRNA targets of fragile X mental retardation protein (FMRP) are enriched for genetic asso

207 Fragile X mental retardation protein (FMRP) binds to and regulates the tr

208 n 1 (FMR1) gene and loss of fragile X mental retardation protein (FMRP) cause fragile X syndrome (FXS

209 The loss of fragile X mental retardation protein (FMRP) causes fragile X syndrome (FX

210 Loss of fragile X mental retardation protein (FMRP) causes fragile X syndrome (FX

211 how the loss of function of fragile X mental retardation protein (FMRP) causes fragile X syndrome (FX

212 of the gene (Fmr1) encoding Fragile X mental retardation protein (FMRP) causes increased mRNA transla

213 f the Fmr1 gene and loss of fragile X mental retardation protein (FMRP) expression.

214 CE STATEMENT The absence of Fragile X Mental Retardation Protein (FMRP) from birth results in develop

215 How the loss of fragile X mental retardation protein (FMRP) in different brain cell types

216 aused by the absence of the Fragile X Mental Retardation Protein (FMRP) in neurons.

217 used by a deficiency of the fragile X mental retardation protein (FMRP) in neurons.

218 Fragile X mental retardation protein (FMRP) is a multifunctional RNA-bind

219 Fragile X Mental Retardation Protein (FMRP) is a regulatory RNA binding p

220 The Fragile X Mental Retardation Protein (FMRP) is an RNA binding protein tha

221 Fragile X mental retardation protein (FMRP) is an RNA-binding protein abu

222 Fragile X mental retardation protein (FMRP) is thought to regulate neuron

223 esis resulting from loss of fragile X mental retardation protein (FMRP) is thought to underlie cognit

224 Fragile X mental retardation protein (FMRP) is well-studied, as its loss

225 X syndrome, the absence of fragile X mental retardation protein (FMRP) leads to defects in plasticit

226 Fragile X mental retardation protein (FMRP) loss causes Fragile X syndrom

227 that the effect of loss of fragile X mental retardation protein (FMRP) on these pathways is brain re

228 062) and for targets of the fragile X mental retardation protein (FMRP) pathway (10 observed vs. 4.4

229 ceptor signaling though the fragile X mental retardation protein (FMRP) pathway may underlie synaptic

230 The fragile X mental retardation protein (FMRP) plays an important role in no

231 ndem Agenet domain (TAD) of fragile X mental retardation protein (FMRP) protein is considered to be a

232 Fragile X mental retardation protein (FMRP) sculpts synaptic refinement i

233 Whether fragile X mental retardation protein (FMRP) target mRNAs and neuronal act

234 By using the Fragile X Mental Retardation Protein (FMRP), an abundant neuronal granule

235 at results from the loss of fragile X mental retardation protein (FMRP), an mRNA binding protein that

236 XS is caused by the loss of fragile X mental retardation protein (FMRP), an mRNA binding protein, and

237 More recently, fragile X mental retardation protein (FMRP), an RNA-binding protein that

238 Fragile X mental retardation protein (FMRP), an RNA-binding protein, has

239 use of its interaction with Fragile X mental retardation protein (FMRP), its upregulation in transfor

240 slation and is dependent on fragile X mental retardation protein (FMRP), the protein that is deficien

241 Fragile X mental retardation protein (FMRP), the protein that is lacking

242 rom the loss of function of fragile X mental retardation protein (FMRP), which represses translation

243 XS is caused by loss of the fragile X mental retardation protein (FMRP), which translationally repres

244 srupts the transcription of Fragile X Mental Retardation Protein (FMRP).

245 ), results from the loss of Fragile X mental retardation protein (FMRP).

246 abrogated expression of the Fragile X Mental Retardation Protein (FMRP).

247 ng translational suppressor Fragile X Mental Retardation Protein (FMRP).

248 thanol treatment, requiring fragile-X mental retardation protein (FMRP).

249 partial or complete loss of fragile X mental retardation protein (FMRP).

250 e process is antagonized by fragile X mental retardation protein (FMRP).

251 of the RNA-binding protein fragile X mental retardation protein (FMRP).

252 ale mice, we tested whether Fragile X Mental Retardation Protein (FMRPO), the protein whose absence c

253 10(-4)) and targets of the Fragile X mental retardation protein (P=0.0018).

254 The resulting absence of fragile X mental retardation protein 1 (FMRP) leads to both pre- and post

255 ociated genes such as Fmr1 (fragile X mental retardation protein 1).

256 ein synthesis controlled by fragile X mental retardation protein and on Arc signaling.

257 on-independent role for the fragile X mental retardation protein as a regulator of neural excitabilit

258 Absence of fragile X mental retardation protein causes fragile X syndrome.

259 tions of cytoplasmic CYFIP1-fragile X mental retardation protein complexes.

260 nhibition by overexpression of the fragile X retardation protein Fmr1.

261 ion-independent function of fragile X mental retardation protein has a major role in regulating ion-c

262 entify a novel role for the fragile-X mental retardation protein in the posttranscriptional regulatio

263 Loss of the Fragile X mental retardation protein leads to excessive excitatory compar

264 co-localizes with YB-1 and fragile X mental retardation protein on stress granules in response to ar

265 These results suggest that Fragile X Mental Retardation Protein regulates dendritic HCN channels via

266 atory complex that includes fragile X mental retardation protein, DEAD box helicase 5, and the poly(A

267 inding protein 1 (YB-1) and fragile X mental retardation protein, proteins that function in translati

268 study shows that replacing Fragile X Mental Retardation Protein, which is absent in Fragile X syndro

269 mics and interacts with the fragile X mental retardation protein.

270 But developmental retardation, reduced brood size, altered survival and in

271 to investigate pertechnetate (Tc(VII)O4(-)) retardation, reduction, and rate scaling in three sedime

272 We identified fragile X mental retardation-related protein 1 (FXR1P), a RNA binding pro

273 Here, we show that the fragile X mental retardation-related protein 2 (FXR2P) cooperates with FM

274 % were achieved with remarkably little rate retardation relative to ethylene homopolymerizations.

275 ess, onychodystrophy, osteodystrophy, mental retardation, seizures) to non-syndromic hearing loss.

276 nt neuropathological symptoms such as mental retardation, seizures, and epilepsy.

277 f the first protein content and its absolute retardation signal is equal to that of the second protei

278 d its relevant leverage theory relied on the retardation signal of chip moving reaction boundary elec

279 d that (i) there was a leverage principle of retardation signal within the TDP of two pure proteins,

280 out mice died postnatally with severe growth retardation, skeletal defects, and kidney and lung abnor

281 with wide-ranging symptoms, including mental retardation, speech and language impairment and other ne

282 nidentified syndrome characterized by growth retardation, spine malformation, facial dysmorphisms, an

283 ptic proteins in normal and Fragile X mental retardation syndrome (FXS) model mouse cortex, and revea

284 Silver-Russell syndrome (SRS) is a growth retardation syndrome in which loss of methylation on chr

285 complex containing alpha-thalassaemia/mental retardation syndrome X-linked (ATRX) and death-domain-as

286 Here, we identify alpha-thalassemia retardation syndrome X-linked (ATRX) as a novel physical

287 Alpha thalassemia/mental retardation syndrome X-linked chromatin remodeler (ATRX)

288 hromatic nearly 90 degrees transmitted phase retardation through the metasurface is precisely charact

289 um of clinical outcomes, ranging from mental retardation to microcephaly, caused by congenital HCMV i

290 (zinc finger, myeloproliferative, and mental retardation-type 3) as a chromatin-interacting protein t

291 e grik1-1 grik2-1 double mutant shows growth retardation under regular growth conditions.

292 ith clinical manifestations including mental retardation, vision impairment, and sensorineural hearin

293 hat shed light on the conditions under which retardation vs. acceleration of loss of variability occu

294 ted with mutism, withdrawal, and psychomotor retardation, which constitute the neurovegetative featur

295 anergia, fatigue, lassitude and psychomotor retardation, which cross multiple pathologies, including

296 was characterized by an initially low local retardation, which increased as collagen fibers remodele

297 crocephaly, absent speech, hypotonia, growth retardation with prenatal onset, feeding difficulties, s

298 rabidopsis thaliana Alpha Thalassemia-mental Retardation X-linked (ATRX) ortholog and show that ATRX

299 activation of ATRX (alpha-thalassemia mental retardation X-linked) represents a defining molecular al

300 deletions of ATRX (Alpha Thalassemia/Mental Retardation, X-linked) that generate in-frame fusion (IF