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1 those receiving combination of abciximab and reteplase.
2 ase and abciximab versus those randomized to reteplase.
3 lity at 30 days compared with a full dose of reteplase.
4 mutant derivatives such as tenecteplase and reteplase.
5 nment (streptokinase, 4.1%; alteplase, 4.3%; reteplase, 4.5%; combined streptokinase and alteplase, 4
6 tients receiving abciximab with reduced-dose reteplase (5 U double bolus) showed an 86% incidence of
7 ed with reduced doses of either alteplase or reteplase, abciximab achieved 91% and 83% inhibition of
8 taly, and Poland were treated with half-dose reteplase, abciximab, heparin, and aspirin, and randomly
9 d, open-label trial to compare the effect of reteplase alone with reteplase plus abciximab in patient
10 reinfarctions with the combination than with reteplase alone, and there was less need for urgent reva
12 ed, compared with 468 (5.6%) in the combined reteplase and abciximab group (odds ratio 0.95 [95% CI 0
13 assess whether the combination of half-dose reteplase and abciximab provides any propitious benefits
14 e randomized to the combination of half-dose reteplase and abciximab versus those randomized to retep
18 ht to compare platelet characteristics after reteplase and alteplase therapy in the setting of the Gl
23 arly treatment with abciximab plus half-dose reteplase (combination-facilitated PCI) or with abcixima
24 2.4%, p = 0.62) among patients randomized to reteplase compared to those receiving combination of abc
26 and a half dose of a plasminogen activator (reteplase) did not significantly reduce mortality at 30
27 t 7 days occurred in 3.5% of patients in the reteplase group and 2.3% of patients in the combination
28 urred in 692 (8.38%) of 8260 patients in the reteplase group and 698 (8.38%) of the 8328 patients in
29 At 30 days, 488 (5.9%) of patients in the reteplase group had died, compared with 468 (5.6%) in th
33 arction were randomly assigned standard-dose reteplase (n=8260) or half-dose reteplase and full-dose
34 d after reperfusion with either alteplase or reteplase or reduced doses of these agents with concomit
35 ssible, fibrinolytic therapy with alteplase, reteplase, or tenecteplase at full dose should be admini
36 o compare the effect of reteplase alone with reteplase plus abciximab in patients with acute myocardi
38 oprotein inhibitors; RR 1.88 [1.24-2.86] for reteplase plus parenteral anticoagulants plus glycoprote
40 ospital initiation of the bolus fibrinolytic reteplase (rPA) and determined the time saved by prehosp
41 se (accelerated infusion), tenecteplase, and reteplase should be considered over streptokinase and no
42 e and abciximab was not superior to standard reteplase, the 0.3% absolute (5% relative) decrease in 3
45 o receive (intravenously) a standard dose of reteplase (two 10-U boluses, 30 minutes apart) or the co
50 ted infusion of alteplase, tenecteplase, and reteplase with parenteral anticoagulants as background t