ライフサイエンスコーパス: retinae

1 al distribution of Y-junctions across entire retinae.

2 ynaptic elements in wild-type and Lamb2-null retinae.

3 protein of similar size in bovine and murine retinae.

4 ung (4-year-old) and old (80-year-old) human retinae.

5 interneuron in the rod pathway of mammalian retinae.

6 ension of axons from temporal regions of the retinae.

7 ictly equivalent projection sites of the two retinae.

8 ed by the cone mechanism in mixed (rod/cone) retinae.

9 localization in photoreceptors of Rs1h(-/Y) retinae.

10 at occupy corresponding positions on the two retinae.

11 m a sequence of 2D images projected onto the retinae.

12 for clinical imaging of normal and diseased retinae.

13 n both wild-type and degenerated ex vivo rat retinae.

14 ed progeny from uninjured and light-lesioned retinae.

15 ee-dimensional (3D) environment onto the two retinae.

16 e due to donor cells integrating within host retinae.

17 are cone-evoked or those from immature mouse retinae.

18 h corresponding points in the left and right retinae.

19 ed to retinal degeneration in Brg1-deficient retinae.

20 nocturnal, with small eyes and rod-dominated retinae.

21 significantly downregulated in myopic mouse retinae.

22 There was 1 case of extramacular sclopetaria retinae.

23 umatic maculopathy and extramacular commotio retinae.

24 nd differentiation defects in Id2a-deficient retinae.

25 y ultra-deep in situ Hi-C analysis on murine retinae.

26 nt with human and animal studies of commotio retinae.

27 oblastomas as compared to three normal human retinae.

28 higher in retinoblastoma than in human fetal retinae.

29 h proteins in mouse, rat, rabbit, and monkey retinae.

30 ppressor p53 was highly expressed in the OIR retinae.

31 iation defects associated with pRb-deficient retinae.

32 For extramacular commotio retinae, 117 patients were identified, of whom 58 had ad

33 ntravitreal hemorrhages (14.7%) and commotio retinae (21.1%).

34 For macular commotio retinae, 53 patients were identified, of whom 34 had ade

35 nner plexiform layer of male and female mice retinae (8-16 weeks old) using the GABA sensor iGABASnFR

36 When the method is applied to mouse retinae a significant increase in the DOPAC/DA ratio is

37 and capillaries in brain slices and isolated retinae, allowing investigators to probe the role of cap

38 vivo in developing pigmented and albino rat retinae along with other parameters of cell division to

39 ed in retinoblastoma relative to human fetal retinae and a subset of samples had somatic mutations th

40 bino mammals have specific deficits in their retinae and in the pattern of decussation at their optic

41 pression similar to those in MYCN-transduced retinae and MYCN(A) retinoblastomas in patients.

42 specifically eliminated microglia in murine retinae and optic nerves with high efficiency.

43 unoassay measurements of BDNF protein in the retinae and SC of normal and BDNF-treated hamsters demon

44 We examine ageing primate retinae and show elevated stress but low inflammation.

45 Among its oscillators are the pineal gland, retinae, and a hypothalamic structure assumed to be homo

46 inflammatory ICAM-1 is increased in diabetic retinae, and it is implicated in pathogenesis of retinop

47 , which transmits light information from the retinae, and the geniculohypothalamic tract (GHT) from t

48 However, once development is complete, their retinae appear relatively normal, although many photorec

49 Their retinae are crisply layered following the typical verteb

50 on requires that inputs arising from the two retinae are integrated and precisely organized within ce

51 uropean starling, Sturnus vulgaris, even the retinae are morphologically asymmetrical in terms of pho

52 s of photoreceptor cells found in vertebrate retinae are organized in specific patterns, which are im

53 Despite their diversity, vertebrate retinae are specialized to maximize either photon catch

54 n cells were overproduced in Uhrf2-deficient retinae at the expense of VSX2+ RPCs.

55 half of the ganglion cells in whole-mounted retinae bound antibodies against both isoforms.

56 n purified from rod outer segments of bovine retinae by immunoaffinity chromatography in octyl glucos

57 s (r-iPSCs) and scored their ability to make retinae by using a standardized quantitative protocol ca

58 The coordinates in reconstructed retinae can be transformed to visuotopic coordinates.

59 sulting in stable patterns of outflow on the retinae centered on the point of fixation.

60 However, mosaic retinae composed of wild-type and flo cells show that de

61 ation pathway was reduced in Uhrf2-deficient retinae, consistent with locally reduced 5hmC in their g

62 We propose a model in which light-exposed retinae contain a mixed population of phosphorylated and

63 ion and differentiation, with Id2a-deficient retinae containing an abundance of proliferative retinob

64 an vision is that it occurs through "duplex" retinae containing both rod and cone photoreceptors, the

65 The outer epithelial layer of zebrafish retinae contains a crystalline array of cone photorecept

66 c mice and transplanted into adult recipient retinae; CrxGFP is a marker of cone and rod photorecepto

67 nous dopamine release from isolated goldfish retinae cultured in continuous darkness for 56 h clearly

68 In contrast, dendrites in untreated retinae degenerated slowly after the axonal trauma and n

69 Retinae derived from f-iPSCs had fewer amacrine cells an

70 In the complementary experiment, retinae derived from NeuroD-null mice demonstrated a two

71 The original and the duplicate neural retinae differentiate and laminate with mirror-image pol

72 nt project to different locations on the two retinae, differing principally in their horizontal coord

73 Whereas explants from nasal retinae extended fibers across their natural target popu

74 population, fibers from temporal regions of retinae failed to invade areas of growing posterior tect

75 Using whole retinae from adult mice, we performed immunohistochemist

76 xperiments, these parameters are compared in retinae from animals with different targeted deletions o

77 1-dependent fluorescence was detected in rat retinae from birth, albeit at low levels.

78 ng effect of 100 nM CuCl(2) is absent in the retinae from Ca(v)2.3-deficient mice, but prominent in C

79 Examination of retinae from homozygous viable mutants indicated two maj

80 Retinae from mice lacking p57(Kip2) exhibited inappropri

81 Nissl staining of retinae from normal adult and 5,7-DHT-treated hamsters r

82 In birds, the pineal gland and retinae have been defined as pacemakers within this syst

83 Lineage analyses of vertebrate retinae have led to the suggestions that cell fate decis

84 Microarray analysis of zymosan-treated retinae identified several cytokines (CXCL13, endothelin

85 n undergo retinal differentiation to produce retinae in 34 d.

86 mation from either the dorsal or the ventral retinae in both median and lateral ocelli, with only thr

87 largely documented in the rodent and primate retinae in recent years.

88 Analysis of retinae in SV2B knock-out mice revealed a strong reducti

89 Patients with ONHD had thicker retinae in the inner annulus compared with patients with

90 h those of cells located in matched areas of retinae in which the density of beta ganglion cells had

91 n retinal locations of extramacular commotio retinae, in order of frequency, were inferotemporal (37%

92 mparisons between the macular and peripheral retinae indicate a largely consistent yet distinct devel

93 estricted outgrowth pattern is observed when retinae innervate their targets in rodents.

94 the types of different neurons in mammalian retinae is now close to being completely known for a few

95 of photo-receptor activation present on our retinae; it is composed of segregated surfaces, organize

96 e use of a novel observation: isolated mouse retinae kept in standard media for routine physiologic r

97 differences between images formed on the two retinae (known as binocular disparity).

98 In the contralateral retinae, labeled RGCs were most numerous and widespread,

99 In mouse retinae lacking Sirt6, effectors of glycolytic flux were

100 in vivo retroviral infection of newborn rat retinae led to an altered photoreceptor phenotype, while

101 al lamina disruption of embryonic day 3 to 6 retinae led to the retraction of the end feet of the neu

102 ner segments in isolated intact neural mouse retinae, maintained by superfusion.

103 progenitor cells persisted in Brg1-deficient retinae, making them more susceptible to retinoblastoma.

104 enhancers are also active in the developing retinae, many having features of cell- and developmental

105 Reduced VA after extramacular commotio retinae may represent occult macular injury or previousl

106 abrasion (n = 7), hyphema (n = 9), commotio retinae (n = 5), intraretinal hemorrhage (n = 3), preret

107 hromatin accessibility in cells from healthy retinae of 20 human donors through single-cell multiomic

108 d retinal degeneration in sectioned archived retinae of 26 macaque monkeys with unilateral V1 ablatio

109 and assessed expression by mRNA analysis in retinae of 51 unselected post mortem eye specimens from

110 ERG waveforms from light-adapted retinae of all patients showed reduced amplitudes of the

111 abetes-related nitric oxide increases in the retinae of diabetic animals.

112 We recently reported an increase in Grx1 in retinae of diabetic rats and in rat retinal Muller glial

113 ncreases VEGF mRNA and protein levels in the retinae of diabetic rats.

114 was generated in chicken eggs and tested in retinae of goldfish and rat, and rat caudate putamen, by

115 depolarizing bipolar cells isolated from the retinae of goldfish.

116 glion cell recordings were obtained from the retinae of macaques (Macaca fascicularis).

117 The retinae of many bird species contain a depression with h

118 other retinal cell specific markers in adult retinae of mice.

119 istry with cell type-specific markers in the retinae of mouse, rat, rabbit, and monkey.

120 robust expression of exogenous PCDH15 in the retinae of Pcdh15(KI) mice, sustained recovery of electr

121 Horizontal cells are absent in retinae of Prox1-/- mice and misexpression of Prox1 in p

122 am (ERG) response and rhodopsin level in the retinae of Rho(P23H/+) knock-in mice at 1 month of age.

123 creased the photoreceptor cell number in the retinae of Rho(P23H/+) mice compared to vehicle control.

124 The retinae of Rpe65(-/-)Grk1(-/-) mice had negligible opsin

125 es located in the outer nuclear layer of the retinae of the 4 older patients were observed (termed ou

126 r retinal tubulation) were identified in the retinae of the GA patients.

127 Expression of the TBK1 transgene in the retinae of these mice was demonstrated by real-time PCR.

128 mRNA expression was assessed in post-mortem retinae of three men with the red, green and green-red g

129 Rat retinae of various ages were stained immunohistochemical

130 tch pathway component gene expression, while retinae overexpressing id2a possess reduced expression o

131 icantly reduced in larval and adult rab28 KO retinae (p < .05).

132 ve found that in the adult Rb;p130-deficient retinae p107 compensation prevents ectopic proliferation

133 Id2a-deficient retinae possess elevated levels of Notch pathway compone

134 DM4 and MDM2 mRNA and protein in human fetal retinae, primary retinoblastomas, retinoblastoma cell li

135 The results suggest that in some vertebrate retinae, prolonged darkness (light-history) may regulate

136 ddle cone photoreceptors, whereas Pde6h(-/-) retinae remained PDE6H-negative.

137 the approximately 20 RGC types in mammalian retinae respond to diverse visual features and events is

138 ression is decreased by over 80%, KI/KI mice retinae retain comparable 11-cis-retinal levels with WT.

139 ble retinal injury, with central sclopetaria retinae, retinal necrosis, and surrounding commotio reti

140 Examination of transgenic IAP-null retinae revealed a failure of P84 to become associated w

141 Immunohistochemistry on murine retinae revealed an overlap of the retinoschisin-Na/K-AT

142 Analysis of mutant retinae reveals an extensive loss of photoreceptors and

143 y Western blot analysis of bleached isolated retinae showed little dephosphorylation of rhodopsin for

144 g immunoelectron microscopy of mouse and rat retinae showed that VGAT immunoreactivity was localized

145 Here we examine young and aged primate retinae stained to distinguish S from M/L-cones.

146 Eliprodil is neuroprotective of retinae subjected to either an excitotoxic or ischemic c

147 izontal cell processes in primate and rodent retinae suggested that mammalian horizontal cells releas

148 -);p130(-/-) or Rb(-/-);p107(-/-);p130(+/-), retinae suggesting that one copy of Rb or p130 was suffi

149 ors is significantly increased in Math5(-/-) retinae, suggesting a binary change in cell fate from RG

150 functional wild-type RGC types also in rd10 retinae, suggesting that at this early degenerative stag

151 Finally, analysis of P4, P7, P12, and P15 retinae suggests that the apical horizontal cell process

152 ions associated with sky vision and the area retinae temporalis (ART), the predicted homolog of the a

153 SCs more efficiently produced differentiated retinae than did embryonic stem cells (ESCs) or fibrobla

154 nce of functional photoreceptors within host retinae that express an array of donor-specific proteins

155 ts identified defects in tet2(-/-);tet3(-/-) retinae that included delayed specification of several r

156 Consequently, in photopic retinae, the application of APB disrupts the ON-channel

157 In the ipsilateral retinae, the small number of labeled cells were concentr

158 tron microscopy of adult Macaca fascicularis retinae to examine the 3D structure of mitochondria in r

159 rns (i.e., images) can be applied to primate retinae to predictably push the spiking activity of targ

160 ate proliferation in the p57(Kip2)-deficient retinae to preserve the correct proportion of the major

161 d to other neurotrophins, as well as RGCs in retinae treated with BDNF but in areas not directly expo

162 In human and murine retinae, TTLL5 localized to the centrioles at the base o

163 RNA-seq analysis of human retinae uncovered harmonin_a1 as the most abundant trans

164 as quantified (qAF) in subjects with healthy retinae using a standardized approach.

165 The median presenting VA retinae was 20/30; 55 patients (95%) recovered to >/= 20

166 ighest density of cells in the contralateral retinae was found in the inferior and nasal retinal quad

167 f endogenous dopamine released from in vitro retinae was greater during the subjective day than the s

168 of ON- and OFF-CBCs in Bk(-/-) and wild-type retinae was indistinguishable.

169 eature of both ipsilateral and contralateral retinae was the paucity of labeled cells found in the do

170 l gene expression analysis of Id2a-deficient retinae, we identify a number of additional intrinsic an

171 By applying varied light stimuli to isolated retinae, we reveal over 40 different GABA-releasing neur

172 Here, using explanted cultured retinae, we show that ectopic N-Myc induces cell cycle e

173 ng immunohistochemistry in macaque and human retinae, we show that NaV1.1 is concentrated in an axon

174 Two groups of retinae were compared, those recorded after 10 min dark

175 Retinae were harvested from mice ranging in age from bir

176 Macaque retinae were immunostained with monoclonal antibodies di

177 Embryonic retinae were transplanted to intracranial locations in n

178 Rabbit and human retinae were used to investigate if there are any specie

179 The retinae were whole-mounted, viewed under fluorescence, a

180 s (FEM) render a stable world jittery on our retinae, which can be expected to harm neural coding.

181 , retinal necrosis, and surrounding commotio retinae with specific photoreceptor cell death and spari

182 of alpha and beta ganglion cells from normal retinae with those of cells located in matched areas of