ライフサイエンスコーパス: retinal photoreceptor

1 ion cells (pRGCs) represent a third class of retinal photoreceptor.

2 the inner segment and synaptic terminals of retinal photoreceptors.

3 tenuated the detrimental influence of SNP to retinal photoreceptors.

4 viding cells and to the connecting cilium of retinal photoreceptors.

5 is crucial for the function and survival of retinal photoreceptors.

6 rriers targeted to the rod outer segments of retinal photoreceptors.

7 ing protein family expressed specifically in retinal photoreceptors.

8 ransported, as earlier proposed, from distal retinal photoreceptors.

9 n of the circadian oscillator in the Xenopus retinal photoreceptors.

10 ession of these motors is highly enhanced in retinal photoreceptors.

11 uires neither rods nor cones, the only known retinal photoreceptors.

12 Ogre is required in the presynaptic retinal photoreceptors.

13 by these genes are expressed exclusively in retinal photoreceptors.

14 cleus is entrained to the day/night cycle by retinal photoreceptors.

15 t negative Xenopus CLOCK specifically in the retinal photoreceptors.

16 mplexed with GTP/Talpha in mature vertebrate retinal photoreceptors.

17 alized rhabdomeral membranes from Drosophila retinal photoreceptors.

18 t animals indicate a contribution from inner retinal photoreceptors.

19 the regulation of cGMP phosphodiesterase in retinal photoreceptors.

20 rons, including hippocampal mossy fibres and retinal photoreceptors.

21 tantially protected from light damage to the retinal photoreceptors.

22 here is a slowly progressive degeneration of retinal photoreceptors.

23 t mammals is thought be mediated entirely by retinal photoreceptors.

24 athological consequences of this mutation in retinal photoreceptors.

25 s essential for the survival and function of retinal photoreceptors.

26 ORG assessment of physiological integrity of retinal photoreceptors.

27 mmalian cochlear inner hair cells (IHCs) and retinal photoreceptors.

28 generates 11-cis retinal chromophore for the retinal photoreceptors.

29 egment photocurrents of Lampetra fluviatilis retinal photoreceptors.

30 t/dark cycle is mediated exclusively through retinal photoreceptors.

31 dness result from the dysfunction or loss of retinal photoreceptors.

32 y, distribution, and spectral sensitivity of retinal photoreceptors.

33 ted in inflammatory pathologic conditions in retinal photoreceptors.

34 vative bound to rhodopsin and cone opsins of retinal photoreceptors.

35 y sighted subjects can be supported by inner retinal photoreceptors.

36 disease characterized by progressive loss of retinal photoreceptors.

37 rate that this defect occurs at the level of retinal photoreceptors.

38 mately lead to blindness due to the death of retinal photoreceptors.

39 belief that rods and cones are the exclusive retinal photoreceptors.

40 maintaining the health and integrity of the retinal photoreceptors.

41 Crocin protects retinal photoreceptors against light-induced cell death.

42 In retinal photoreceptors, amplification by the phototransd

43 y stereocilia of inner ear hair cells and to retinal photoreceptor and pigmented epithelium cells.

44 gamma) binding protein, highly expressed in retinal photoreceptor and pineal cells, yet whose physio

45 Mice with a 1.8-kb IRBP promoter develop retinal photoreceptor and pineal tumors.

46 studies suggest a novel function of PILRB in retinal photoreceptors and an association of PILRB, but

47 transporter has been described in vertebrate retinal photoreceptors and bipolar cells, the molecular

48 study a canonical pair of sister cell types, retinal photoreceptors and bipolar cells, to identify th

49 els are crucial for synaptic transmission in retinal photoreceptors and bipolar neurons.

50 wide differences in DNA methylation between retinal photoreceptors and brain neurons.

51 o lead to the loss of temporal resolution in retinal photoreceptors and deficient synaptic transmissi

52 Da) matrix protein expressed specifically in retinal photoreceptors and developing cochlear hair cell

53 is required for the long-term maintenance of retinal photoreceptors and for the development of cochle

54 ht waves through realistically reconstructed retinal photoreceptors and found that cone photoreceptor

55 Both SMC1 and SMC3 localized to the cilia of retinal photoreceptors and Madin-Darby canine kidney cel

56 mfort and dazzling glare depend on different retinal photoreceptors and nociceptive brain pathways in

57 Specialized sensory cilia such as retinal photoreceptors and olfactory cilia use diverse i

58 yclic nucleotide-gated (CNG) ion channels of retinal photoreceptors and olfactory neurons are multime

59 tics of light-evoked responses in vertebrate retinal photoreceptors and ON-bipolar cells.

60 involved in differentiation and survival of retinal photoreceptors and photoentrainment of circadian

61 n protein that is expressed predominantly in retinal photoreceptors and pinealocytes.

62 ecoverin expressed in tumor cells may damage retinal photoreceptors and play a role in the pathogenes

63 the retina, is driven synaptically, because retinal photoreceptors and second-order cells tonically

64 Synaptic transmission between retinal photoreceptors and second-order neurones is cont

65 nerating the electrical response to light in retinal photoreceptors and to odorants in olfactory rece

66 characterized by progressive degeneration of retinal photoreceptors and, consequently, visual decline

67 The confocal IOS predominantly results from retinal photoreceptors, and can be used to map localized

68 le for sensitivity to UV and visible light), retinal photoreceptors, and ocular lenses.

69 ve is the light-induced hyperpolarization of retinal photoreceptors, and the b-wave is the depolariza

70 prCAD is expressed only in retinal photoreceptors, and the prCAD protein is localiz

71 at following an intraocular injection of SNP retinal photoreceptors are affected.

72 Retinal photoreceptors are highly metabolic and their en

73 fects of drusen on the synaptic machinery of retinal photoreceptors are investigated.

74 Signals from retinal photoreceptors are processed in two parallel cha

75 Retinal photoreceptors are susceptible to mitochondrial

76 These nanoparticles anchored on retinal photoreceptors as miniature NIR light transducer

77 ve heterogeneity of transcribed sequences in retinal photoreceptors because of alternate splicing and

78 The photoresponse in retinal photoreceptors begins when a molecule of rhodops

79 When applied to retinal photoreceptors, bicarbonate enhanced the circula

80 visually driven signals as they flow through retinal photoreceptor, bipolar, and ganglion cells.

81 -ATPase ("flippase") located in membranes of retinal photoreceptors, brain cells, and testis, where i

82 gene fusion expressed high levels of FGF2 in retinal photoreceptors but developed no retinal neovascu

83 cked the membranous stacks characteristic of retinal photoreceptors but were ciliated and contained n

84 es are being developed to bypass degenerated retinal photoreceptors by directly activating retinal ne

85 5 to inner ear hair cell stereocilia, and to retinal photoreceptors by immunocytochemistry.

86 dition to rods and cones, mammals have inner retinal photoreceptors called intrinsically photosensiti

87 In retinal photoreceptors, CaM binds to the CNGB subunit of

88 sion of beta-galactosidase (beta gal) on the retinal photoreceptor cell arrestin promoter, in conjunc

89 es the opportunity to longitudinally monitor retinal photoreceptor cell death in preclinical studies.

90 role of heme metabolism in the regulation of retinal photoreceptor cell development.

91 Circadian shedding of retinal photoreceptor cell discs with subsequent phagocy

92 Mouse retinal photoreceptor cell generation and morphogenesis

93 maintain the blood-retinal barrier, sustain retinal photoreceptor cell health and function, and may

94 Retinal pigment epithelial and retinal photoreceptor cell lines were treated with TP de

95 esis and cohesion of stereocilia bundles and retinal photoreceptor cell maintenance or function.

96 ramide metabolism plays an important role in retinal photoreceptor cell survival and apoptosis.

97 th transgenic mice that expressed betagal in retinal photoreceptor cells (arrbetagal mice).

98 Several proteins found in retinal photoreceptor cells (guanylate cyclase activatin

99 Melatonin is synthesized in retinal photoreceptor cells and acts as a neuromodulator

100 ns-retinal triggers phototransduction in the retinal photoreceptor cells and causes ultimately the se

101 gene promoter are hypomethylated in DNA from retinal photoreceptor cells and pineal gland compared to

102 sorders characterized by degeneration of the retinal photoreceptor cells and progressive loss of visi

103 of Hmgb1 at the protein level occurs in rat retinal photoreceptor cells and to a lesser extent in bi

104 Retinal photoreceptor cells are particularly vulnerable

105 vertebrates is triggered when light strikes retinal photoreceptor cells causing photoisomerization o

106 Retinal photoreceptor cells contain the highest concentr

107 In vivo, AANAT activity in chicken retinal photoreceptor cells exhibits a circadian rhythm

108 c factors (NTFs) are effective in protecting retinal photoreceptor cells from the damaging effects of

109 ses selective irreversible apoptotic loss of retinal photoreceptor cells in vivo.

110 ngly, an eye with restored cornea, iris, and retinal photoreceptor cells is formed when a surface fis

111 era) visual system contains three classes of retinal photoreceptor cells that are maximally sensitive

112 is a canonical G protein-mediated cascade of retinal photoreceptor cells that transforms photons into

113 links photoactivation of visual pigments in retinal photoreceptor cells to a change in their membran

114 LEDGF enhanced survival of retinal photoreceptor cells under serum starvation and h

115 ects of LEDGF on survival of embryonic chick retinal photoreceptor cells under serum starvation and h

116 hed transgenic mice expressing human E2F1 in retinal photoreceptor cells under the regulation of the

117 pression pattern of LEDGF in embryonic chick retinal photoreceptor cells was investigated with protei

118 vels were both high in the inner segments of retinal photoreceptor cells where energy-demanding activ

119 Melatonin receptors are expressed in retinal photoreceptor cells, and this study was undertak

120 showed that both GCAP genes are expressed in retinal photoreceptor cells, but GCAP2 was nearly undete

121 oA are used as alternative Nmt substrates in retinal photoreceptor cells, even though they do not exh

122 ythmically expressed in the cytoplasm of the retinal photoreceptor cells, the only other described ve

123 Notably, expression is not observed in retinal photoreceptor cells, the opsin-containing cells

124 urnin is rhythmically transcribed in Xenopus retinal photoreceptor cells, which contain endogenous ci

125 n nuclear receptor expressed specifically by retinal photoreceptor cells.

126 r responsible for the capture of a photon in retinal photoreceptor cells.

127 ransduction in olfactory sensory neurons and retinal photoreceptor cells.

128 rtant during phototransduction in vertebrate retinal photoreceptor cells.

129 the choriocapillaris, the vascular supply of retinal photoreceptor cells.

130 laevis its mRNA is specifically expressed in retinal photoreceptor cells.

131 -sensitive regulator of phototransduction in retinal photoreceptor cells.

132 MD) leads to dysfunction and degeneration of retinal photoreceptor cells.

133 to adaptation to background illumination in retinal photoreceptor cells.

134 pe voltage-gated Ca(2+) channels (Cav1.4) in retinal photoreceptor cells.

135 te and continuously supply 11-cis-retinal to retinal photoreceptor cells.

136 ion and proper development of hair cells and retinal photoreceptor cells.

137 ndition characterized by progressive loss of retinal photoreceptor cells.

138 atic structures due to its expression in the retinal photoreceptor cilia.

139 such asymmetry in any bird and suggests that retinal photoreceptor composition should be assessed dur

140 While luminance adaptation can begin at the retinal photoreceptors, contrast adaptation has been sho

141 In retinal photoreceptors, coupling plays important roles i

142 right light can cause visual dysfunction and retinal photoreceptor damage in humans and experimental

143 activation of this gene in zebrafish induced retinal photoreceptor defects that were rescued by human

144 ammatory response was associated with marked retinal photoreceptor degeneration and massive neuronal

145 is pigmentosa comprises a group of inherited retinal photoreceptor degenerations that lead to progres

146 The activity and survival of retinal photoreceptors depend on support functions perfo

147 eptor whose loss-of-function causes abnormal retinal photoreceptor development and degeneration.

148 eptor gene, NR2E3, cause a disorder of human retinal photoreceptor development characterized by hyper

149 gulates NR2E3 and is necessary for zebrafish retinal photoreceptor development.

150 progenitor cell marker, in the biogenesis of retinal photoreceptor disk arrays.

151 ayer morphology, large areas of RPE atrophy, retinal photoreceptor dysfunction, and microglial cell a

152 Retinal photoreceptors entrain the circadian system to t

153 Retinal photoreceptors establish selective contacts with

154 These novel retinal photoreceptors express the photopigment melanops

155 ganglion cells (ipRGCs) are non-rod/non-cone retinal photoreceptors expressing the visual pigment, me

156 onses to Arm signaling that specify distinct retinal photoreceptor fates.

157 mon causes of blindness involve the death of retinal photoreceptors, followed by progressive inner re

158 ead throughout the CNS and is observed among retinal photoreceptors from essentially all vertebrates.

159 functional cell monolayer that separates the retinal photoreceptors from the choroid, are prevalent i

160 -expressing ipRGCs, showing that these inner retinal photoreceptors function as retinal irradiance de

161 Retinal photoreceptors have a distinct transcriptomic pr

162 In retinal photoreceptors, highly polarized organization of

163 dimension to an essential role for LPCAT1 in retinal photoreceptor homeostasis.

164 sed on the differential color sensitivity of retinal photoreceptors, however the developmental progra

165 Retinal photoreceptors in Cep290(ko/ko) mice lack connec

166 E) performs specialized functions to support retinal photoreceptors, including regeneration of the vi

167 ory light avoidance behavior in mice lacking retinal photoreceptors, indicating reconstitution of lig

168 age formation, the light that is detected by retinal photoreceptors influences subcortical functions,

169 al photoreceptors (rods and cones) and inner retinal photoreceptors (intrinsically photosensitive ret

170 e, we address the critical question of which retinal photoreceptor is responsible for coordinating th

171 The cGMP-specific phosphodiesterase (PDE) of retinal photoreceptors is a central regulatory enzyme in

172 specifically and transiently labeling dying retinal photoreceptors is detectable in anesthetized ani

173 n vivo, the circadian clock localized in the retinal photoreceptors is necessary for its rhythmicity.

174 nes constitute approximately 1% of adult rat retinal photoreceptors, it was estimated that the relati

175 In retinal photoreceptors, L-VGCCs are responsible for neur

176 SNP caused an increase in the number of retinal photoreceptors labeled for DNA breakdown by the

177 o have potential for success but only if the retinal photoreceptor layer is intact, as in the early-d

178 pically, patients lose vision when the outer retinal photoreceptor layer is lost, and so the therapeu

179 nes remains enigmatic as cones reside in the retinal photoreceptor layer, shielded by the blood-retin

180 complement activation capacity and a thicker retinal photoreceptor layer.

181 ian rhythm of melatonin synthesis in Xenopus retinal photoreceptor layers is driven by rhythmic chang

182 in the circadian system in cultured Xenopus retinal photoreceptor layers.

183 Here, we investigated whether the inner-retinal photoreceptor melanopsin could represent a third

184 eins of the EF-hand superfamily that inhibit retinal photoreceptor membrane guanylyl cyclase (retGC)

185 The retinal photoreceptor mosaics generated by ERICA have a

186 ,5'-monophosphate phosphodiesterase (PDE) in retinal photoreceptors, must be deactivated for the ligh

187 Rods and cones are retinal photoreceptor neurons required for our visual se

188 ion is achieved by comparing the inputs from retinal photoreceptor neurons that differ in their wavel

189 In contrast, neither RH5-expressing retinal photoreceptors nor RH2-expressing ocellar photor

190 ning electron microscopy to characterize the retinal photoreceptors of spine-bellied (Lapemis curtus)

191 evious work in the literature describing the retinal photoreceptors of T. s.

192 A circadian clock is located in the retinal photoreceptors of the African clawed frog Xenopu

193 degeneration of cerebellar Purkinje neurons, retinal photoreceptors, olfactory bulb mitral neurons, a

194 Visual transduction in retinal photoreceptors operates through a dynamic interp

195 These results indicate that a rhythm of retinal photoreceptor outer segment disk shedding exists

196 acts access to the confined space within the retinal photoreceptor outer segment signaling compartmen

197 tages of the disease is caused by atrophy of retinal photoreceptors, overlying retinal pigment epithe

198 (TLRs) in the innate immune response causes retinal photoreceptor oxidative stress and mitochondrial

199 sion, when mutated can result in an isolated retinal photoreceptor phenotype.

200 Retinal photoreceptor phosphodiesterase (PDE6) is unique

201 In vertebrate retinal photoreceptors, photoisomerization of opsin-boun

202 Retinal photoreceptors possess specialized cilia.

203 study was undertaken to investigate whether retinal photoreceptor (PR) cells lacking MTs are more su

204 Circadian oscillators in retinal photoreceptors provide a mechanism that allows p

205 Despite the loss of all known retinal photoreceptors, rd/rd cl mice showed normal supp

206 Timely termination of the light response in retinal photoreceptors requires rapid inactivation of th

207 In retinal photoreceptors, RGS9.Gbeta5 is bound to the memb

208 Both outer retinal photoreceptors (rods and cones) and inner retina

209 on within the protein-coding region of a new retinal photoreceptor-specific gene, ELOVL4, in all affe

210 acterize transgenic protein localization and retinal photoreceptor structure and function.

211 Gap junctions in retinal photoreceptors suppress voltage noise and facili

212 Transplantation of fetal retinal photoreceptor suspensions into the subretinal sp

213 In the retinal photoreceptor synapse and the cerebellar mossy f

214 ion cells (ipRGCs) comprise a third class of retinal photoreceptors that are known to mediate physiol

215 Light produces a graded hyperpolarization in retinal photoreceptors that decreases their release of s

216 In mammals, pineal function is influenced by retinal photoreceptors that project to the suprachiasmat

217 In vertebrate retinal photoreceptors, the absorption of light by rhodo

218 Synaptic transmission from retinal photoreceptors to downstream ON-type bipolar cel

219 the intrinsic ability of regenerating adult retinal photoreceptors to reconstitute properly differen

220 The outer segments of vertebrate retinal photoreceptors undergo periodic shedding of memb

221 Retinal photoreceptors use the heterotrimeric G protein

222 In retinal photoreceptors, vectorial transport of cargo is

223 al visual structures by receiving input from retinal photoreceptors via bipolar and amacrine cells.

224 to supply 11-cis-retinal from the RPE to the retinal photoreceptors was accompanied by a massive accu

225 To stimulate different retinal photoreceptors, we used a 1-second 640-nm flash

226 In retinal photoreceptors where rootlets appear particularl

227 Rac1 is expressed abundantly in mammalian retinal photoreceptors, where it is activated in respons

228 observations, we show here that adult mouse retinal photoreceptors, which are terminally differentia

229 occur through either extraretinal (brain) or retinal photoreceptors, which mediate sensitivity to blu

230 ataract removal, we have found evidence that retinal photoreceptors will swiftly realign towards the