ライフサイエンスコーパス: reverse turn

1 ontacts to residues of the proteasome Pro-17 reverse turn.

2 ening by repositioning the proteasome Pro-17 reverse turn.

3 ing step corresponds to the formation of the reverse turn.

4 of the substituted residue to be found in a reverse turn.

5 ropane dipeptide isosteres could stabilize a reverse turn.

6 aining amphiphilic beta-strands separated by reverse turns.

7 ino acid sequences TPEE and NPTY form type I reverse turns.

8 the direction of the peptide chain define a reverse turn, a common motif and recognition site in pro

9 antiparallel strands connected by a modified reverse turn (A27 replaced by D), a natural disulfide cr

10 This conformation, comprising two reverse turns, allows each pair of the three variable do

11 -terminally to its homeodomain-which forms a reverse turn and inserts into a hydrophobic pocket on th

12 ant challenge for the construction of stable reverse turn and loop structures.

13 (536)Y-N-G-H-P-P(541), which forms a type I' reverse turn and provides several interactions with the

14 engages the D-recruitment site (beta7-beta8 reverse turn and the alphaD-alphaE helix) of ERK2.

15 Residues 66 to 68 may form a reverse turn and the last four amino acids (69 to 72) ma

16 ype I beta-turns are the most common type of reverse turn, and they exhibit a statistical consensus s

17 y 721 and Gly 722 are located in a Type III' reverse turn, and this type of secondary structural moti

18 icate array of 29 beta-strands, 25 classical reverse turns, and 2 small alpha-helices.

19 e RGD sequence has a significant amount of a reverse turn around the RGD region, is a potent inhibito

20 eptide bound in a single conformation with a reverse turn at residues NPVY.

21 between helix II and beta-strand B, and the reverse turn between beta-strands C and D.

22 odor-evoked calcium responses in AWC(ON) but reversed turning biases in odor gradients.

23 otif with a helical turn followed by an open reverse turn centered at Gly-348, a helix-terminating C

24 sequence requirements for stabilization of a reverse turn conformation in a short peptide in water so

25 was shown to adopt a unique acyclic peptoid reverse-turn conformation.

26 evealing that peptoid macrocycles can form a reverse-turn conformation.

27 sitions are used to constrain a peptide to a reverse-turn conformation.

28 at all analogs except for SS-31 form compact reverse turn conformations in the membrane-bound state.

29 cules via a repertoire of transient hydrated reverse turn conformations.

30 ds, is evaluated as minimalist scaffolds for reverse-turn conformations.

31 )-Tyr(747) (NPLY) have a propensity to adopt reverse-turn conformations.

32 cate a region of order (beta-sheet), a tight reverse turn containing the proline, and a second region

33 scan receptors for biological recognition of reverse turns containing cis-amide bonds by the incorpor

34 h enhanced aromatic sequon in its respective reverse turn context.

35 re stabilized upon glycosylation in specific reverse turn contexts: a five-residue type I beta-turn h

36 er peptide analogues with the same conserved reverse turn demonstrated in the larger peptides.

37 beta-turn dipeptide ehr=Pro a useful general reverse-turn dipeptide.

38 before a glycosylated asparagine in distinct reverse turns facilitates stabilizing interactions betwe

39 A three nucleotide reverse turn in loop 1 positions a protonated cytidine,

40 is significantly different from that of the reverse turn in MPMV NC.

41 ere shown to give the greatest population of reverse turns in a previous study.

42 relationships of C(alpha)-C(beta) vectors of reverse turns in proteins were subjected to principal co

43 s had dramatic effects on the populations of reverse turns in solution.

44 re found to be superior to the best designed reversing turns in terms of nucleating beta-sheet struct

45 secondary structures (beta-strands, helices, reverse turns) in short peptide sequences.

46 -furanoid sugar amino acid frameworks act as reverse-turn inducers with a U-shaped conformation, wher

47 ations revealed a galactan main chain with a reverse turn involving the beta-1-->6 link between the t

48 A reverse turn is observed at the conserved GPGX sequence.

49 A similar C-terminal reverse turn-like structure was observed recently in the

50 rminal of Nle(3)-gamma-MSH-NH(2), there is a reverse-turn-like structure, suggesting that there might

51 The four-residue reverse turn -Met56-Gly-Asp-Glu59- in the Clostridium be

52 ion of the lactam ring, can act as effective reverse-turn mimics and have proven to be useful interme

53 , but slower protection is observed around a reverse turn near the C-terminus of the protein.

54 Structural studies identified a reverse turn occurring in the His-DPhe-Arg-Trp domain, w

55 orial region of the dimeric capsule, and the reverse turn of the chain and the methyl terminal in eac

56 atic sequon, a structural motif found in the reverse turns of some N-glycoproteins, to facilitate fac

57 The data suggest that a transient reverse turn or loop-type structure may be a requirement

58 that differ from each other in the designed reverse turn segment.

59 ot be readily accommodated within the native reverse turn structure.

60 e design and synthesis of an acyclic peptoid reverse-turn structure, in which N-aryl side chains outf

61 Most reverse-turn structures could be mimicked effectively wi

62 The mutation beta3(Y747A) disrupted this reverse-turn tendency and markedly reduced the affinity

63 th peptides when bound to HPTRX/CDEF adopt a reverse turn that is consistent with the C-cap structure

64 With two antiparallel helices connected by a reverse turn, the alpha-helical hairpin structure may be

65 oline is placed at the i + 1 position of the reverse turn to promote a type II' beta-turn, and (iii)

66 osylation without having to alter the native reverse turn type.

67 -MSH it has been demonstrated further that a reverse-turn type conformation exists at this pharmacoph

68 incorporates two proline residues to induce reverse turns, was designed to form a triple-stranded be

69 et(56)-Gly-Asp-Glu(59)- forms a four-residue reverse turn which undergoes a conversion from a mix of

70 e appearance of images when their colors are reversed, turning white to yellow and silver to gold, an