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1 suggest that thaxtomins are synthesized non-ribosomally.
2 -keto or gamma-keto amide can be synthesized ribosomally.
3 cyl-tRNA synthetases capable of charging any ribosomally accepted molecule onto an orthogonal suppres
4 ulation killing factor (SKF) is a 26-residue ribosomally assembled and posttranslationally modified s
7 acted from a ubiquitous enzyme family toward ribosomally derived peptide natural product biosynthesis
10 re, we report the genome-guided discovery of ribosomally derived, fatty-acylated lipopeptides, termed
11 A (PA) is a member of the growing family of ribosomally encoded and post-translationally modified pe
12 natural product pathways are the only known ribosomally encoded and posttranslationally modified pep
15 llin as a model system, a thiopeptide in the ribosomally encoded family of natural products that exhi
19 are natural-product antibiotics derived from ribosomally encoded peptides that undergo extensive post
22 roxy-D-valine (D-Hyv), was identified within ribosomally expressed polypeptide chains of four conopep
25 yclopentane carboxylic acid (gamma(2)), were ribosomally introduced into a library of thioether-macro
26 esent results further extend the examples of ribosomally mediated formation of peptide bond analogues
28 relates with antibacterial activity, and the ribosomally more active compounds show activity against
29 of which would generate a sgmRNA encoding a ribosomally occupied open reading frame (dORF) located d
31 unusual amino acids and are synthesized non-ribosomally on amino acid-activating polyenzyme template
32 c acid motif can be introduced into peptides ribosomally or via solid-phase synthesis using alpha-hyd
33 mes and substrates obtained from a family of ribosomally produced and post-translationally modified p
34 volved in the maturation of PapA, which is a ribosomally produced and posttranslationally modified po
40 ut its discovery raises the possibility that ribosomally produced viral or mammalian proteins that co
41 ethanobactins (Mbns) are a growing family of ribosomally produced, post-translationally modified natu
42 re copper (Cu) for pMMO by secreting a small ribosomally produced, posttranslationally modified natur
50 iverse biosynthetic gene clusters coding for ribosomally synthesized and post-translationally modifie
52 and lanthipeptides-two different families of ribosomally synthesized and post-translationally modifie
53 odified enzymes gleaned from microbial RiPP (ribosomally synthesized and post-translationally modifie
54 ring enzymes involved in the biosynthesis of ribosomally synthesized and post-translationally modifie
57 en implicated in the oxidative maturation of ribosomally synthesized and post-translationally modifie
59 a pyrimidone motif from a widely distributed ribosomally synthesized and post-translationally modifie
60 iosynthetic gene clusters (BGCs) that encode ribosomally synthesized and post-translationally modifie
61 nd trachea for gene clusters encoding RiPPs (ribosomally synthesized and post-translationally modifie
62 ead conservation of a BGC encoding a cryptic ribosomally synthesized and post-translationally modifie
63 machine-learning tool for the prediction of ribosomally synthesized and post-translationally modifie
65 talyze formation of thioether cross-links in ribosomally synthesized and post-translationally modifie
68 group of natural products that belong to the ribosomally synthesized and post-translationally modifie
69 ipknot-like structures, are a large class of ribosomally synthesized and post-translationally modifie
70 natural products that belong to the class of ribosomally synthesized and post-translationally modifie
73 es are a large and sequence-diverse class of ribosomally synthesized and post-translationally modifie
76 to d-amino acids during biosynthesis of the ribosomally synthesized and post-translationally modifie
77 any bioactive molecules, particularly in the ribosomally synthesized and post-translationally modifie
78 Pyritides are a recently described class of ribosomally synthesized and post-translationally modifie
92 yl macrocyclic linkages in three families of ribosomally synthesized and post-translationally modifie
95 malian microbiome streptococci that code for ribosomally synthesized and post-translationally modifie
97 rococcal cytolysin is a toxic, two-component ribosomally synthesized and post-translationally modifie
98 the study of natural products, including the ribosomally synthesized and post-translationally modifie
102 zole-containing pyritides (thiopeptides) are ribosomally synthesized and post-translationally modifie
105 ted biosynthetic gene clusters that code for ribosomally synthesized and post-translationally modifie
106 ous expression, we produced fuscimiditide, a ribosomally synthesized and post-translationally modifie
107 classes of peptide and protein therapeutics: ribosomally synthesized and post-translationally modifie
108 fibrosis, (iii) show the presence of a novel ribosomally synthesized and post-translationally modifie
109 el to combine enzymes sourced from bacterial ribosomally synthesized and post-translationally modifie
110 rmatic tools have bolstered the discovery of ribosomally synthesized and post-translationally modifie
112 identified an abundance of gene clusters for ribosomally synthesized and post-translationally modifie
113 ofactor in many prokaryotes, produced from a ribosomally synthesized and post-translationally modifie
115 ding nonribosomal peptides, polyketides, and ribosomally synthesized and post-translationally modifie
118 motif present in several enzymes that act on ribosomally synthesized and post-translationally modifie
119 des (PKs), nonribosomal peptides (NRPs), and ribosomally synthesized and post-translationally modifie
120 he broad family of bioactive peptides called ribosomally synthesized and post-translationally modifie
123 s to the formation of azolines and azoles in ribosomally synthesized and post-translationally modifie
124 orithm, improved predictions for terpene and ribosomally synthesized and post-translationally modifie
126 Lasso peptides are a class of bioactive ribosomally synthesized and post-translationally modifie
128 of a novel class of natural products called ribosomally synthesized and post-translationally modifie
130 Bottromycin A2 is a structurally unique ribosomally synthesized and post-translationally modifie
131 lex, bioactive natural products derived from ribosomally synthesized and post-translationally modifie
133 oloquinoline quinone (PQQ) is a product of a ribosomally synthesized and post-translationally modifie
134 atural products that belong to the family of ribosomally synthesized and post-translationally modifie
136 ynthesis machinery of the growing variety of ribosomally synthesized and post-translationally modifie
137 nthipeptides represent an important group of ribosomally synthesized and post-translationally modifie
140 scovered previously during genome mining for ribosomally synthesized and posttranslational modified p
141 osynthesis of Ruminococcin C (RumC), a novel ribosomally synthesized and posttranslationally modified
143 eptide-derived antimicrobial agents that are ribosomally synthesized and posttranslationally modified
144 e bicyclic peptides and report that they are ribosomally synthesized and posttranslationally modified
145 ive bacteria, QS is often mediated by cyclic ribosomally synthesized and posttranslationally modified
146 ances, the study highlights the potential of ribosomally synthesized and posttranslationally modified
153 dvances in understanding the biosynthesis of ribosomally synthesized and posttranslationally modified
159 iologically active molecules known as RiPPs (ribosomally synthesized and posttranslationally modified
164 the biosynthesis of ruminococcin C (RumC), a ribosomally synthesized and posttranslationally modified
168 ng peptides (lanthipeptides) are a family of ribosomally synthesized and posttranslationally modified
173 er recent years, several examples of natural ribosomally synthesized circular proteins and peptides f
178 to broaden the structural diversity of this ribosomally synthesized lantibiotic, we now report the r
179 J25 (MccJ25) is a 21-residue plasmid-encoded ribosomally synthesized lariat-protoknot antibacterial p
180 knowledge of the prevalence and diversity of ribosomally synthesized natural products (RNPs) is rapid
182 The biosynthesis of a considerable number of ribosomally synthesized peptide antibiotics involves the
183 iously unknown biochemical processes using a ribosomally synthesized peptide as scaffold for non-ribo
184 Mutacin 1140 is a member of a family of ribosomally synthesized peptide bacteriocins called lant
188 ction of coelibactin, an uncharacterized non-ribosomally synthesized peptide with predicted sideropho
189 precedented architecture consisting of a non-ribosomally synthesized peptide, a polyketide component
190 alpha-amino acid into a beta-amino acid in a ribosomally synthesized peptide, via an electrophilic in
192 We describe the enzymatic bromination of ribosomally synthesized peptides and develop protocols f
194 from screening trillion-member libraries of ribosomally synthesized peptides containing non-canonica
195 enzyme transforms up to 29 different linear ribosomally synthesized peptides into a library of polyc
196 time, the post-translational modification of ribosomally synthesized peptides is a rapidly expanding
197 onal analysis of the lantibiotics, which are ribosomally synthesized peptides produced by gram-positi
203 moieties in nonribosomal peptides (NRPs) and ribosomally synthesized post-translationally modified pe
208 -containing natural products is derived from ribosomally synthesized preproteins that undergo a casca
211 AMPs), >12 000 are synthetic, about 2700 are ribosomally synthesized, and about 170 are non-ribosomal
212 recently described class of plant-specific, ribosomally synthesized, and posttranslationally modifie
215 Some methane-oxidizing bacteria use the ribosomally synthesized, posttranslationally modified na
216 tudied group of eukaryotic tyrosine sulfated ribosomally synthesized, posttranslationally modified pe
218 y of enzymes involved in the biosynthesis of ribosomally synthesized, posttranslationally modified pe
223 iversification of moroidins, which are plant ribosomally-synthesized and posttranslationally-modified
224 cing chip to display an immense diversity of ribosomally translated proteins and peptides and then ca