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1 nctate lines of density that run through the rootlet.
2 the acetylated microtubules and along the D4 rootlet.
3 f the gene for rootletin, a component of the rootlet.
4 g-sought structural component of the ciliary rootlet.
5 m their normal localization near microvillar rootlets.
6 It was originally cloned from human hair rootlets.
7 mal basal bodies and cytoplasmic microtubule rootlets.
8 lation of neurons among the trigeminal motor rootlets.
9 exist between the sciatic notch to the nerve rootlets.
10 er ear hair cell cytoskeleton, forming dense rootlets.
11 tous actin density and abnormal stereociliar rootlets.
12 at the junction between the lower and upper rootlets.
13 iate preferential binding to centrioles over rootlets.
14 tly, via microtubules, to some stereociliary rootlets.
15 rrelated with shorter acetylated microtubule rootlets.
16 hereditary deafness DFNB28, is localized to rootlets.
17 number of single spindle afferents in dorsal rootlets.
18 t the ciliary base in photoreceptors lacking rootlets.
19 In the mutant, ciliated cells are devoid of rootlets.
21 s indicate that pericentriolar fibres termed rootlets, also known as the centrosome linker, entangle
23 at support microvilli have their pointed-end rootlets anchored in a filamentous meshwork referred to
24 propose a model of eyespot assembly wherein rootlet and photoreceptor direct EYE2 to an area of the
26 ate with the basal bodies and their striated rootlets and form complexes named ciliary adhesions (CAs
29 functional paradigm for Nesprin1 at ciliary rootlets and suggest that the wide spectrum of human pat
30 of Nesprin1alpha with photoreceptor ciliary rootlets and the functional interaction between rootleti
32 ceptor patches were not restricted to the D4 rootlet, and more anterior eyespots correlated with shor
34 localizes to cilia-forming basal bodies and rootlets, and is required for ciliary adhesion complexes
35 function of the rotational stiffness of the rootlets; and 4) how the standing tension of the tip lin
40 l tissue sections, we found that microvillar rootlets are decorated with the severing protein, cofili
47 n brewer's spent grain (BSG) and barley malt rootlets (BMR), common waste products of beer processing
50 s into uniquely dense bundles reminiscent of rootlets but distinct from bundles formed by espin, an a
51 ls of pejvakin-deficient mice develop normal rootlets, but hair bundle morphology and mechanotransduc
52 on of the intercentriolar linker and ciliary rootlet component rootletin, and rootletin knockdown in
53 Pejvakin binds to and colocalizes with the rootlet component TRIOBP at the base of stereocilia in i
54 the daughter four-membered (D4) microtubule rootlet, comprises an elliptical patch of rhodopsin phot
59 in reveal, respectively, the way stereocilia rootlets contribute to the hair bundle's mechanical prop
62 ioned adjacent to the daughter four-membered rootlet (D4), a unique bundle of acetylated microtubules
65 s and in a mix of afferents in lumbar dorsal rootlets (dorsal root potential [DRP]) with bipolar elec
66 s where rootlets appear particularly robust, rootlets extend from the basal bodies to the synaptic te
71 cilium, they are especially dependent on the rootlet for structural integrity and long-term survival.
72 strategically located to augment stereocilia rootlet formation and their pivot point flexibility for
74 ructions of membrane-associated and purified rootlets from mouse retina using cryo-electron tomograph
77 developed largely unbranched, root-hairless rootlets, here we report that stigmarian rootlets were h
79 oreover, pejvakin localizes to stereociliary rootlets in hair cells and is required for stereocilia m
80 cells, and ANKRD24 no longer localizes with rootlets in mice lacking TRIOBP-5; exogenous DsRed-TRIOB
82 cord explants and formation of "miniventral rootlets." In neonatal mice, PTN protected the facial mo
83 eurography, which separates intradural nerve rootlets into normal, partial mild, severe, and complete
90 a major structural component of the ciliary rootlet, is located at the basal bodies and centrosomes
94 es the apical plasma membrane with the lower rootlet, maintaining a normal distribution of TRIOBP-5.
96 striated fiber is incomplete in this mutant, rootlet microtubules can be misplaced, and multiflagella
99 ure that in the algal ancestor served as the rootlet of the flagellar basal bodies is required for pa
102 aralogs Rootletin and C-Nap1, assembles into rootlets of diverse lengths among sensory neuron subtype
105 Nesprin1 are integral components of ciliary rootlets of multiciliated ependymal and tracheal cells.
106 tletin recruits Nesprin1alpha at the ciliary rootlets of photoreceptors and identify asymmetric NE ag
107 Nerve impulses were recorded from the dorsal rootlets of the L7-S1 segments of the spinal cord, and a
108 ith respect to flagellar number, microtubule rootlet organization, cleavage furrow positioning, and b
110 t a density of approximately 25,600 terminal rootlets per meter of rhizomorph, and were covered in ro
111 flections of up to +/-35 degrees, ruling out rootlet prestressing as the basis for sliding adhesion.
113 investigated the structure and dimensions of rootlets relative to the stereocilia in apical (low-freq
117 eferentially expressed in the I. echinospora rootlets, S. moellendorffii roots and A. thaliana roots
121 eate nucleus at 15-25 weeks after the dorsal rootlet section, than those mapped only 7 days postlesio
125 nk membranes may serve as part of the stable rootlet structure for anchoring the tip links of stereoc
126 ar plates and association with stereociliary rootlets suggest that this isozyme participates in rigid
127 s-positive vesicles adjacent to the striated rootlet suggests a transport role for this cytoskeletal
129 -bands, associated with accumulations on the rootlet surface, and discrete (D)-bands corresponding to
130 We show that flexible protrusions on the rootlet surface, which emanate from the cross-striations
134 root entry zone and the lateral funiculi via rootlets that had become adherent to the lateral spinal
135 neous rhythmic activity in hypoglossal (XII) rootlets that occur in synchrony with periodic bursts of
136 ortical fibers in oral apparatus and ciliary rootlets, the apical filament ring and to inner arm (14S
140 f C-NAP1, although components of the ciliary rootlet were aberrantly localized away from the base of
141 fting with preceding normal intradural nerve rootlets were diagnosed by an experienced neuroradiologi
142 ess rootlets, here we report that stigmarian rootlets were highly branched, developed at a density of
143 gene expression signatures of I. echinospora rootlets were similar to gene expression signatures of t
144 Annular ANKRD24 continues into the lower rootlet, where it surrounds and binds TRIOBP-5, which it
145 ler that localizes specifically to the basal rootlets, where the pointed ends of core bundle filament
147 Stereocilia that lack TPRN develop warped rootlets with gradual loss of TRIOBP-5 and ANKRD24 from
148 or the XIIMN while recording from XII nerve rootlets (XIIn) as an index of respiratory motor output.