ライフサイエンスコーパス: rotor

1 ator-unit modulates its association with the rotor.

2 sociation rate on the force delivered to the rotor.

3 nstitute the membrane domain of the enzyme's rotor.

4 d TICT phenomenon and behaved like molecular rotor.

5 olded-unfolded equilibrium of an N-arylimide rotor.

6 protonates an acidic glutamate in the c-ring rotor.

7 ss the membrane generates the turning of the rotor.

8 e central stalk and c-ring form the enzyme's rotor.

9 tween transmembrane proteins (stators) and a rotor.

10 l stalk, holding them static relative to the rotor.

11 the membrane domain constitute the enzyme's rotor.

12 ue at the interface between stator units and rotor.

13 ronic devices based on fluorescent molecular rotors.

14 ed and investigated as redox-gated molecular rotors.

15 EES-based analysis was conducted to identify rotors.

16 to be highly efficient fluorescent molecular rotors.

17 of LGE signal intensity and the presence of rotors.

18 d to highlight high-curvature wavefronts and rotors.

19 ranged between -5 and -9 kJ mol(-1) for </=5 rotors.

20 s singularity points and visually highlights rotors.

21 d nonrotational singularity points and false rotors.

22 alyzed to study phase singularity points and rotors.

23 single mapping catheter enabled detection of rotors.

24 rroborated well with the spatial location of rotors.

25 fferent collective modes are selected by the rotors.

26 loting the motion of optically-trapped micro-rotors.

27 e separated by a sublattice of BCO molecular rotors.

28 Crystals of molecular rotor 1 with a central 1,4-phenylene rotator linked to t

29 (11), fluorescent pairs(12,13) and molecular rotors(14-16) have been designed to measure intracellula

30 port a loosely packed crystal of dendrimeric rotor 2 and the fast dynamics of all its aromatic groups

31 Increasing amounts of the larger molecular rotor 2 in the solid solution results in significant dyn

32 Molecular rotor 2 with a central 1,4-diethynyl-2,3-difluorophenyle

33 is identified a total number of 410 electric rotors, 47.8% were located in the left atrium and 52.2%

34 the first example of the use of a molecular rotor, a BODIPY dye, to quantitatively visualize the vis

35 y is determined by tumbling of the molecular rotor about the long acene axis.

36 batic cooling due to rotor stretching during rotor acceleration and the reverse process on rotor dece

37 Rotors act like revolving doors limiting the number of p

38 whereas no significant conduction slowing or rotor activity occurred in the LA of monocrotaline-treat

39 ant rate-dependent RA conduction slowing and rotor activity, including stable rotors in 4 of 11 PH ra

40 llows for the identification of sources with rotor activity.

41 ing that mutant stators not engaged with the rotor allow some proton leakage.

42 d to increase </=100% the time with detected rotors, although provoked the apparition of false rotors

43 low as 1 sample point in the vicinity of the rotors, an accuracy as high as 86% (P<0.001) was obtaine

44 A molecular rotor analogue 3 has properties similar to those of 2, s

45 ch consists of a single acetylene (C(2)H(2)) rotor anchored to a chiral atomic cluster provided by a

46 a catenane-based chemically driven molecular rotor and a synthetic molecular assembler or pump, are d

47 rage conditions, enzymatic digestion, stator-rotor and bead motion-based homogenizing combined with c

48 Both stator-rotor and bead motion-based homogenizing were found to r

49 ine analysis revealed no differences between rotor and distant sites in dominant frequency or Shannon

50 agellar motor, protein molecules in both the rotor and stator exchange with freely circulating pools

51 tics of atrial electrograms used to identify rotors and describe acute procedural outcomes of FIRM-gu

52 al electrogram characteristics expected from rotors and did not differ quantitatively from surroundin

53 studies evaluating the relationship between rotors and fibrosis in patients with persistent atrial f

54 aim of this study was to analyze the role of rotors and focal sources in a large academic registry of

55 gly support the mechanistic role of biatrial rotors and focal sources in maintaining AF in diverse po

56 ution required for correct identification of rotors and focal sources is a linear function of spatial

57 METHODS AND Simulations of rotors and focal sources were performed to estimate the

58 echnique to examine the relationship between rotors and LGE signal intensity in patients with persist

59 ly around frameworks, can rotate microscopic rotors and magnets fast enough to generate an electric p

60 signal morphologies around the locations of rotors and nonrotors were identified and quantified.

61 al phase/frequency mapping methods to locate rotors and track changes induced by their ablation.

62 ability to detect organized stable drivers (rotors) and target them for therapy.

63 es of subunit a in Fo wrap around the c-ring rotor, and a total of six vertical helices assigned to s

64 Further theoretical studies of this membrane rotor, and of two others with a much stronger and a slig

65 tion is still lacking for the MS-ring of the rotor, and proposed mismatches in stoichiometry between

66 rdiolipin in stabilizing and lubricating the rotor, and, by interacting with the enzyme at the inlet

67 achines based on mechanical bonds, molecular rotors, and light-powered rotary motors.

68 nd a "turnover" in the binding rate data vs. rotor angle for angles greater than [Formula: see text]4

69 ucleotides in F1-ATPase as a function of the rotor angle is further extended in several respects.

70 tion steps have an exponential dependence on rotor angle.

71 (radius at the clot and end of the tube); 2) rotor angulation for the tube holder; 3) revolutions per

72 nsional treatment, which validates the rigid-rotor approach widely used in scattering calculations.

73 The fluorescent emissions from two of the rotors are found to originate, not from the localized ex

74 Rotors are inclusions of omega-phase that aligns under s

75 Stationary rotors are more reliably identified compared with meande

76 oron-dipyrromethene (BODIPY)-based molecular rotors are rigidochromic by means of coupling the rate o

77 rystal form consists of 1D columns of nested rotors arranged in helical arrays with the central aroma

78 The structure of the two-dimensional rotor arrays contained in these surface inclusions was e

79 ture and dimensions of the ordered molecular rotor arrays dictate the correlated switching properties

80 usly prolonged action potential duration and rotors, as well as wave and wavelets in the atria, and t

81 erahertz spectroscopy of gas-phase molecular rotors at room temperature.

82 l mapping do require HDF filtering to detect rotors at the expense of a decreased specificity.

83 our knowledge, viscosity-sensitive molecular rotor based on mesosubstituted boron-dipyrrin used to in

84 rst study demonstrating that the presence of rotors based on NEEES analysis is not directly associate

85 We report a new class of luminescent rotors, based on the sensitized emission of a terbium(II

86 Molecular rotor-based fluorophores (RBFs) have been widely used in

87 Here we introduce origami-rotor-based imaging and tracking (ORBIT), a method that

88 High-resolution rotor bead tracking (RBT) measures DNA torque, twist, an

89 of Cas9 R-loop formation and collapse using rotor bead tracking (RBT), a single-molecule technique t

90 that directly measure DNA rotation, such as rotor bead tracking(1-3), angular optical trapping(4) an

91 perties of a series of phenyl-ring molecular rotors bearing three, five, six, and seven phenyl groups

92 ided accurate fits to measurements of stator-rotor binding over a wide range of loads.

93 lifetime imaging microscopy of the molecular rotor BODIPY C10 in the membranes of live Escherichia co

94 ultrasensitive AP site-specific fluorescent rotor (BTBM-CN(2)) was designed by the strategy of molec

95 A molecular rotor built with a stator formed by two rigid 9beta-mest

96 on to induce single, stable, and centralized rotors by optical S1-S2 cross-field stimulation.

97 angles, slight reorientations of individual rotors can occur, resulting in the rotator arms pointing

98 a two-dimensional array of dipolar molecular rotors can undergo simultaneous rotational switching whe

99 Rotors change the size distribution to P(s) ~ exp(-s/s(0

100 re, decreased core meandering, and increased rotor complexity. Application of quinidine and disopyram

101 d other experimental data on the F(1)-ATPase rotor compliance.

102 ynamic gating for impeding CR in a molecular rotor, comprising an electron donor and acceptor directl

103 In metazoans, their rotors contain a ring of eight c-subunits consisting of

104 detect and track rotors when placed over the rotor core although the low-resolution basket catheter i

105 dicate that self-assembly of two-dimensional rotor crystals produces systems with correlated dynamics

106 ncreased rotor rotation frequency, increased rotor curvature, decreased core meandering, and increase

107 otor acceleration and the reverse process on rotor deceleration.

108 The molecular rotor design achieves a robust >250-500-fold increase in

109 w generation of rod-shaped dipolar molecular rotors designed for controlled insertion into channel ar

110 away from the core region resulted merely in rotor destabilization (ie, drifting).

111 ysis, to prevent misinterpretation and false rotor detection.

112 show that the quantum state of the molecular rotor determines whether or not anisotropic long-range i

113 e functions of these systems, as pendulum or rotor devices or as switchable catalysts, are described.

114 versus the dipolar interactions between the rotors, different collective modes are selected by the r

115 ew generation of double pyridazine molecular rotors differing in intramolecular dipole-dipole spacing

116 s established by the spatial location of the rotor domain (P=0.016).

117 A rotor domain was defined as an area displaying at least

118 Overall, rotor domains (9.2+/-2.2 rotations) displayed higher fre

119 Ablation of rotor domains (ablation line, 3.5+/-0.9 cm) effectively

120 Rotor domains appropriately explain long-standing persis

121 We identified 19 rotor domains in 10 patients (1.8+/-1.1 per patient; 7 i

122 was observed in 2 patients after ablation of rotor domains.

123 ation plus linear ablation of extrapulmonary rotor domains.

124 rotor network and to stabilize the switched rotor domains.

125 d, the motion being activated by an internal rotor driven by a battery mechanism.

126 Tilt-rotor/duct/wing VTOLs are efficient when cruising but co

127 epi)), and prolonged AF cycle length (AFCL); rotor duration, tip trajectory, and variance of AFCL wer

128 s, although provoked the apparition of false rotors during 100% of time.

129 Fluorescent molecular rotor dyes, including Cy3, Cy5, and Alexa Fluor 555, dis

130 The implementation of (2)H-(13)C adiabatic rotor-echo-short-pulse-irradiation cross-polarization (R

131 ort the design, synthesis and application of rotor-fluorogenic D-amino acids (RfDAAs), enabling real-

132 e first set of rationally designed molecular rotor fluorophores that evenly cover a wide range of vis

133 gFluor is comprised of a series of molecular rotor fluorophores that span a wide range of viscosity s

134 ion of localized sustained re-entrant waves (rotors), followed by progressive wave breakdown and roto

135 aggregation induced emission (AIE) molecular rotors for in vitro bio-imaging is reported.

136 ion and mechanistic studies to determine how rotors form, progress, and regress are needed.

137 CL and likely vortex shedding contributes to rotor formation, compensating for any rotor loss, and ma

138 oli is under the control of a complex on the rotor formed from the proteins FliG, FliM, and FliN.

139 r the alpha(3)beta(3)-domain and prevent the rotor from turning.

140 e bond dissociation energy, termed OH "super rotors", from the vacuum ultraviolet photodissociation o

141 understanding of the mechanisms involved in rotor-guided ablation.

142 poor performance obtained, while quasi-rigid rotor harmonic oscillator thermal contributions are impo

143 on is consistent with the finding that their rotors have been arrested at the same point in their rot

144 Rotor identification is accurate and sensitive and does

145 All patients had rotors identified (mean, 2.3+/-0.9 per patient; 72% in l

146 The most highly excited OH(X) super rotors identified at 115.2 nm photolysis have an interna

147 merged, which involves the identification of rotors (ie, local drivers) followed by the localized tar

148 d and the resultant switches in neighbouring rotors imaged.

149 ependent stator complexes which surround the rotor in a ring.

150 etic approach to induce and locally target a rotor in atrial monolayers.

151 o do this, we measured stator-binding to the rotor in mutants in which motors reportedly develop lowe

152 d flow along an axial path using an internal rotor in the blood.

153 slowing and rotor activity, including stable rotors in 4 of 11 PH rats, whereas no significant conduc

154 In summary, the initiation and sustenance of rotors in AF is linked to atrial APD heterogeneity and A

155 is review, we outline the pathophysiology of rotors in animal and in-silico studies of fibrillation,

156 Localized optogenetic targeting of rotors in atrial monolayers could lead to both stabiliza

157 e we report the use of fluorescent molecular rotors in combination with Fluorescence Lifetime Imaging

158 The dynamics of molecular rotors in deuterated MFM-180a-d16 and MFM-181a-d16 were

159 Conversely, ablation of rotors in high-excitability regions migrated spiral wave

160 Second, ablation of rotors in regions of low-excitability (from remodeling)

161 ing tunnelling microscopy enables individual rotors in the arrays to be switched and the resultant sw

162 es values of one out of every five molecular rotors in the chain.

163 es based on a BODIPY core, termed "molecular rotors", in combination with Fluorescence Lifetime Imagi

164 fibrillation (AF) show spiral wave sources (rotors) in nearly all studies including humans, while mo

165 omplex in situ, but also revealed the stator-rotor interaction at an unprecedented detail.

166 Importantly, the stator-rotor interaction induces a conformational change in the

167 The rotation is generated by the stator-rotor interaction, coupled with an ion flux through the

168 by either disengaging or jamming the stator-rotor interaction.

169 sic domain where the turning of the enzyme's rotor is generated from the transmembrane proton-motive

170 The rotor is modeled as a point mass mounted inside a spheri

171 r theoretical predictions, we find that this rotor is significantly H(+) selective, although not suff

172 the yield of vibrationally-excited OH super rotors is detected when exciting the bending vibration o

173 xtracted modulation index-based detection of rotors is feasible with few electrodes and has greater d

174 ple of a porous molecular crystal containing rotors is presented.

175 within an area of simultaneously identified rotor-like electrical patterns in a porcine model of chr

176 Our precipitates act as "rotors": local stress initiates the rotation of inclusio

177 Rotor localization errors are larger for electrogram dat

178 lectrogram signatures in the vicinity of the rotor locations suggest that 62.5% of the rotors occur a

179 as 86% (P<0.001) was obtained in separating rotor locations versus nonrotor locations.

180 tes to rotor formation, compensating for any rotor loss, and may underlie the inefficacy of ranolazin

181 series of stator units surrounding a central rotor made up of two ring complexes, the MS-ring and the

182 Several hundred rotors made from porphyrin-based double-decker complexes

183 n of the stator with respect to the fluorene rotors, make these novel motors particularly promising a

184 analysis revealed accelerated and stabilized rotors manifested by increased rotor rotation frequency,

185 is proposed for single molecule imaging and rotor manipulation experiments on F1-ATPase.

186 Hence, the rotor may have potential applications varying from accur

187 A new class of low-barrier molecular rotors, metal trans-dihydrides, is suggested here.

188 fibrillation (AF) include focal impulse and rotor modulation (FIRM) mapping, and initial results rep

189 Focal impulse and rotor modulation (FIRM) with an endocardial basket cathe

190 brillation With or Without Focal Impulse and Rotor Modulation) trial, in which 92 consecutive patient

191 The elastic compliance resides in the rotor module that includes the membrane-embedded FO c-ri

192 All rotor molecules formed bulk inclusions in a tris( o-phen

193 taneously by reaction of precursor molecular rotor molecules with a metal surface.

194 , followed by progressive wave breakdown and rotor multiplication in both atria.

195 This is determined by the molecular rotor nature of ThT, where the direction of the ThT tran

196 essential to increase electric torque on the rotor network and to stabilize the switched rotor domain

197 e phenomenon is observed only in a hexagonal rotor network due to the degeneracy of the ground-state

198 e simultaneously rotated when in a hexagonal rotor network on a Cu(111) surface by applying biases ab

199 he rotor locations suggest that 62.5% of the rotors occur at locations where the bipolar electrogram

200 /H(+) selectivity of the ion-driven membrane rotor of an F-type ATP synthase.

201 n addition, a constant energetic penalty per rotor of approximately 5-6 kJ mol(-1) was observed in le

202 ng to three rotational states of the central rotor of the enzyme.

203 interact with FliG in the cytoplasmic C ring rotor of the flagellum.

204 cterization of two new fluorescent molecular rotors of boron derived from Schiff bases: (2,4,8,10-tet

205 scale examination of monolayers from all the rotors on a subphase and after transfer is underway and

206 e free rotation of the fluorescent molecular rotor, only observed in the binuclear compound, was decr

207 ple groove machined in a high-pressure valve rotor or by a 1 muL external sample loop, although other

208 n their application as either unidirectional rotors or as chiral multistate switches.

209 nstead of creating lift through conventional rotors or wings, the nanocardboard plates levitate due t

210 A shaft connected to the rotor passes through the peptidoglycan and the outer mem

211 ch that it cannot be regarded as a molecular rotor phase.

212 ong-standing persistent atrial fibrillation, rotors potentially explain atrial fibrillation maintenan

213 herto brightest FBA that has ideal molecular rotor properties for detecting local dynamic motions ass

214 changes in MotA that are transmitted to the rotor protein FliG.

215 hindrance of the core unit exerted upon the rotors proved pivotal in controlling the speed of rotati

216 e-property analysis shows that replacing the rotor pyridyl group of our typical hydrazone switch with

217 to PRF, which include: 1) dimensions of the rotor (radius at the clot and end of the tube); 2) rotor

218 In computer simulations of rotors, reducing I(Na) decreased dominant frequency, inc

219 )-catalytic, peripheral stalk (PS), and c(8)-rotor ring modules.

220 and in other cells lacking the enzyme's c(8) rotor ring or, separately, its peripheral stalk subunits

221 ring the self-assembly of the four-component rotor ROT-2 through metal translocation.

222 sion to the dark S1 state by restricting the rotor rotation enhances fluorescence, which leads to the

223 nd stabilized rotors manifested by increased rotor rotation frequency, increased rotor curvature, dec

224 accomplished this with crystalline molecular rotors self-assembled by halogen bonding of diazabicyclo

225 FIRM-identified rotor sites did not exhibit quantitative atrial electrog

226 no rotational activation at FIRM-identified rotor sites in 23 of 24 patients (96%).

227 ys used centrifugation parameters with equal rotor sizes, angulation of tubes, and/or tube design.

228 100-fold with a quasi-continuous increase of rotor speed during the experiment.

229 Our results show that increasing the rotor speed from 2400rpm to 3600rpm led to a rise in oil

230 Hammer mill rotor speed is a processing variable that can be tuned t

231 the present work, the impact of hammer mill rotor speed on extraction yield and overall quality of s

232 of configurations (screen aperture size and rotor speed) of ultracentrifugal mill on the physicochem

233 traditionally been carried out at a constant rotor speed, which limits the range of sedimentation coe

234 ids, and triterpenoids levels increased with rotor speed.

235 A parameterized rotor-speed schedule is optimized with the goal of achie

236 The resulting rotor-speed schedule may include multiple over- and unde

237 used to further refine the prediction of the rotor-speed schedule.

238 thods to implement experiments with variable rotor speeds, in combination with variable field solutio

239 s, which supports the existence of localized rotors (spiral waves) or focal drivers.

240 ls and unipolar or bipolar electrograms) and rotor stability on resolution requirements were investig

241 lf-limiting VF, was characterized by greater rotor stability: 1) rotors were present in 68 +/- 17% of

242 F0 and F1 complexes connect via a central rotor stalk and a peripheral stator stalk.

243 on as outer water phase was prepared using a rotor stator system.

244 The rotor-stator interface comprises four membrane-embedded

245 o lipid molecules that may contribute to the rotor/stator interaction within the F(o) motor.

246 its N-terminal inhibitory domain at the same rotor/stator interface where the mitochondrial IF1 or th

247 h by monitoring the adiabatic cooling due to rotor stretching during rotor acceleration and the rever

248 mation was verified with the simplest of the rotor structures.

249 embrane-embedded VO region via rotation of a rotor subcomplex.

250 atalytic F1 region via rotation of a central rotor subcomplex.

251 subunit a (aNT) changes conformation to bind rotor subunit d However, insufficient resolution preclud

252 btle random potential of frozen BCO Brownian rotors suppresses magnetic order down to the lowest temp

253 The motor consists of a central rotor surrounded by stator units that couple ion flow ac

254 When the dipole interaction is dominant the rotors swing upwards or downwards in alternating stripes

255 ver strongly resemble the characteristics of Rotor syndrome, suggesting that mutations in ATP11C can

256 g that mutations in ATP11C can predispose to Rotor syndrome.

257 were placed in a specially designed metallic rotor that prevents the heating of absorbing solution an

258 These proteins exert torque on a rotor that spans the inner membrane.

259 alse detections and may incorrectly identify rotors that are not present.

260 ify electrogram morphologies colocalizing to rotors that can be implemented on few electrograms needs

261 ational exchange rates in the self-assembled rotors that directly affect catalysis, and (iii) togglin

262 hat these three frameworks contain molecular rotors that exhibit motion in fast, medium, and slow reg

263 include precise localization and ablation of rotors that maintain the arrhythmia using multielectrode

264 primarily because of the development of MAS rotors that spin at frequencies of 40 to 60 kHz or highe

265 nitial beats of VT/VF identified one or more rotors that were localized along the nodal line separati

266 aging microviscosimetry toolbox of molecular rotors that yield complete microviscosity maps of cells

267 ase of the bacterial flagella, a cytoplasmic rotor (the C-ring) generates torque and reverses rotatio

268 characteristics contributed by the molecular rotors, they can be employed as novel biological fluores

269 ricting the dynamics of AIE-active molecular rotors though multiple external stimuli.

270 it a conducts protons to and from the c-ring rotor through two conserved aqueous channels.

271 ling and understanding the role of molecular rotors through design of organic linkers within porous M

272 d to minimize energy via crosstalk among the rotors through dipolar interactions.

273 and maintenance of VT due to less meandering rotor tip.

274 haft to transmit torque from the cytoplasmic rotor to the external filament.

275 h the ring were brief and sufficient for the rotor to turn only a fraction of a degree in the active

276 Third, ablation may connect rotors to nonconducting anatomic orifices.

277 that uses fluorescently labelled DNA origami rotors to track DNA rotation at the single-molecule leve

278 of arrhythmia mechanisms and the analysis of rotor trajectories with respect to the myocardial substr

279 rnumerary subunits, kept in contact with the rotor turning at speeds up to 350 Hz.

280 l patterns in an array of identical magnetic rotors under an uniform, oscillating magnetic field.

281 dominates over the dipolar interactions, the rotors undergo full rotations, with different quarters o

282 alize the equal rate of rotation of both its rotor units.

283 hing properties of the internal submolecular rotor units.

284 Liquid-vapor partitioning in the NMR rotor was quantified using the (13)C NMR resonances for

285 for the preparation of crystalline molecular rotors was devised from a set of stators and rotators to

286 Next, the core region of these rotors was specifically and precisely targeted by light

287 change rates of the mutant stator around the rotor were not significantly different from wild-type st

288 The spatial locations of rotors were identified using phase maps constructed from

289 Rotors were present in 16 of 19 patients with VF and in

290 characterized by greater rotor stability: 1) rotors were present in 68 +/- 17% of cycles in sustained

291 A series of 16 molecular rotors were synthesized to investigate the ability of n-

292 isengaged and sequestered from the flagellar rotor when bound by MotI.

293 nt resolution to accurately detect and track rotors when placed over the rotor core although the low-

294 tational barrier were isolated using control rotors, which could not form n->pai* interactions.

295 the high sorption properties of a molecular rotor with no permanent voids or channels in its crystal

296 Herein we report a crystalline molecular rotor with rotationally modulated triplet emission that

297 ty by incorporating a magnetically levitated rotor with wide blood-flow paths and an artificial pulse

298 e rotation of six shape-persistent molecular rotors with central naphthalene (2), anthracene (3a, 3b,

299 e design of a crystalline array of molecular rotors with inertial diffusional rotation at the nanosca

300 heses of six triptycene-containing molecular rotors with several single-crystal X-ray diffraction ana

301 Rotors with strong acceptor pai* orbitals, such as keton

302 ered the first crystalline steroid molecular rotor without the alkyne axle.