ライフサイエンスコーパス: safely

1 to move a compound into clinical development safely.

2 logies for engineering cells efficiently and safely.

3 sider a target of 6.5% if it can be achieved safely.

4 the eyes in which treatment may be suspended safely.

5 repair of the inguinal hernia were performed safely.

6 r sectors may be able to resume on-site work safely.

7 d enables foods to be transported and stored safely.

8 dual-mode ultrasound array (DMUA) system to safely ablate the CB in vivo in a spontaneously hyperten

9 eneration and suggest that 3S may be used to safely accelerate healing after injury in diverse clinic

10 FSHD, followed by needle muscle biopsies in safely accessible muscles.

11 that supraphysiological levels of D-mannose safely achievable by drinking-water supplementation supp

12 ram of aerobic and resistance exercise could safely achieve body composition changes in patients with

13 naturally occurring sugar trehalose at doses safely achieved in humans inhibits HIV through two mecha

14 her 28 days of allometric miltefosine dosing safely achieves a higher systemic exposure than linear d

15 ted toward developing AR agonists capable of safely achieving a net negative energy balance while avo

16 olid-state batteries are a proposed route to safely achieving high energy densities, yet this archite

17 idual tissue thermogenesis in humans; how to safely activate BAT and other organ thermogenesis; and h

18 ter selectivity for ABO and the potential to safely administer high doses of huPMN310 are expected to

19 identification of any concerns to address to safely administer PRRT is provided.

20 Conclusion: (18)F-PSMA-11 can be safely administered and results in a mean effective dose

21 The mv mAbs can be safely administered as a single large dose to mice with

22 DAT can be safely administered in a setting with basic critical car

23 ity threshold above which these drugs can be safely administered is not yet defined.

24 onger than 24 weeks are effective and can be safely administered on ambulatory basis.

25 Omalizumab was safely administered to a difficult-to-treat patient popu

26 The procedure was safely adopted by our sample of surgeons.

27 erstanding of these processes can be used to safely advance FUS-BBB opening into a wider range of cli

28 KEY POINTS: To swallow food and liquid safely, airway protection is essential.

29 Treatment that safely alleviates peripheral thyrotoxicosis and reverses

30 United States are determining how to operate safely amid the coronavirus disease 2019 (COVID-19) pand

31 Approaches to safely and effectively augment cellular functions withou

32 echanical clamping and electrohydraulics can safely and effectively benefit postoperative patients al

33 range of anticancer drugs that can be tested safely and effectively by using PEG-b-PLA and PEG-b-PCL

34 NTA percutaneous vascular closure device can safely and effectively close large bore arteriotomies cr

35 ey disease and metabolic acidosis, veverimer safely and effectively corrected metabolic acidosis and

36 Coronary IVL safely and effectively facilitated stent implantation in

37 cated ways to manipulate MiT factor activity safely and effectively must be developed.

38 that utilizes anti-Fel d 1 IgY antibodies to safely and effectively neutralize Fel d 1 after its prod

39 that cDCD LT following postmortem NRP can be safely and effectively performed in selected recipients

40 irst steps toward new therapeutics that more safely and effectively reduce memory decline in menopaus

41 t (MLE4901) could be practice changing as it safely and effectively relieves hot flush symptoms witho

42 n of high molecular weight (MW) free PEG can safely and effectively restore the circulation of PEG li

43 TNFR2 antibody agonist has the potential to safely and effectively treat various inflammatory disord

44 y to carry out patient care responsibilities safely and effectively, is a problem of functioning.

45 HP-diet supplemented with beta-cryptoxanthin safely and efficaciously improves NAFLD.

46 th-old immobilized with a pillow can be done safely and efficaciously without general anesthesia.

47 ammable nucleases-TALENs and CRISPR/Cas9-can safely and efficiently correct genetic defects in cultur

48 ns have the expertise to deploy theranostics safely and efficiently, ensuring that these agents attai

49 ge outcomes significantly if it is performed safely and efficiently.

50 st that the proposed platform may be used to safely and noninvasively enhance the delivery of miRNA-l

51 lication represents a promising strategy for safely and noninvasively treating this debilitating dise

52 ubcellular sites provides a new paradigm for safely and precisely targeting individual properties of

53 A novel lattice-tip catheter could safely and rapidly ablate atrial fibrillation using eith

54 ing-guided PHBP is feasible can be performed safely and results in a significant reduction in fluoros

55 ypothesized that anti-tau2-18 antibodies may safely and specifically reduce pathological tau and prev

56 he present study demonstrated the ability to safely and successfully place percutaneous electrical ph

57 drug-polymer pills in vitro, and the LA-DAAS safely and successfully provided at least month-long rel

58 cessful procedure, ablation can be performed safely and successfully resulting in decreased arrhythmi

59 s of this study indicate that TG can be used safely and the occurrence of hepatotoxicity was low.

60 e of intravenously injected microbubbles, to safely and transiently increase the permeability of the

61 FDG uptake is helpful to achieve biopsy more safely and with a higher yield.

62 sequence, the analysed feed additives can be safely applied as an appropriate material in poultry nut

63 the conclusion that 2'-F nucleotides can be safely applied for the design of metabolically stabilize

64 These findings suggest that CS can be safely applied for transcatheter aortic valve replacemen

65 However, although the two methods can be safely applied in many cases, their usefulness is limite

66 allow off-the-shelf statistical tools to be safely applied to microbiota surveys.

67 cells can be expanded to clinical scale and safely applied to treat patients with cancer.

68 Moreover, DHOPE was safely applied with promising results in a recently perf

69 efficacy is limited by the dose that can be safely applied.

70 Here, we show that AA7075 can be safely arc welded without hot cracks by introducing nano

71 The mechanisms that allow cells to use iron safely are not clear; defects in iron management are a c

72 VSIAs can be treated as effectively and safely as larger aneurysms, by both endovascular and sur

73 th rhbeta-Gal is a tunable approach that can safely augment beta-Gal levels while maintaining NEU1 at

74 TI-RADS can safely avert avoidable FNACs in a significant proportion

75 genomic risk on the basis of MammaPrint may safely avoid adjuvant chemotherapy.

76 pregnancy-adapted algorithm could be used to safely avoid diagnostic imaging in pregnant women with s

77 th lower gastrointestinal bleeding who could safely avoid hospital admission.

78 d advanced chronic liver disease (cACLD) can safely avoid screening endoscopy with a platelet count >

79 Biopsy may be safely avoided.

80 t preferentially at the bottom of the anode, safely away from the separator.

81 the crystal during the deformation, they can safely be considered (deformed) single crystals with a h

82 ommatzsch demonstrated that omalizumab could safely be continued during active COVID-19 infection in

83 re-can identify low-risk individuals who can safely be excluded from a fracture risk screening progra

84 the brain once it has learned that they can safely be ignored.

85 as distractors, once it has learned they can safely be ignored.SIGNIFICANCE STATEMENT We constantly t

86 ter attack, and that mechanism can therefore safely be ruled out.

87 To travel safely behind screens that can protect us from stones an

88 e expected to be expressed at concentrations safely below their solubility limits.

89 phan 2,3-dioxygenase (TDO) and IDO2 may also safely broaden efficacy.

90 al electrical PV isolation could be achieved safely by single pulse IRE ablation.

91 tteries with high energy density that can be safely charged and discharged at high rates are desirabl

92 Pembrolizumab can be safely combined with trastuzumab and chemotherapy and ha

93 Should I associate the positive outcome of safely completing a street-crossing with the situation '

94 r conception strategies empowered couples to safely conceive.

95 e explained and it will be shown what can be safely concluded with their help and what not.

96 n yielding optimal bioeconomic returns while safely conserving resource abundance.

97 Although added sugars most likely can be safely consumed in low amounts as part of a healthy diet

98 changes may allow urgent cancer treatment to safely continue during the COVID-19 pandemic, even durin

99 nt of effector-linked gene drives that could safely control wild populations of Ae. aegypti to combat

100 Veverimer effectively and safely corrected metabolic acidosis.

101 mbined with vitrectomy and gas tamponade can safely create an effective intraretinal barrier to fluid

102 RNA (siRNA) targeting hepatic FXIII-B could safely decrease FXIII-A.

103 vity is critical to allow food processors to safely decrease product holding time.

104 r PVI guided by unipolar signal modification safely decreases procedural burden while ensuring robust

105 trategies to eradicate HIV-1 infection or to safely deescalate antiretroviral treatment.IMPORTANCE Th

106 dentify patients in whom chemotherapy can be safely deescalated and patients likely to respond to imm

107 ulse ultrasound sequence can efficiently and safely deliver drugs to the murine brain.

108 w that ultrasound-activated microbubbles can safely deliver high concentrations of drugs into urothel

109 Radiotherapy can be safely delivered during the coronavirus disease 2019 (CO

110 unds, the BIST-caged neurotransmitter can be safely delivered onto neurons in acutely isolated brain

111 esthetic depth over which anaesthesia may be safely delivered when titrating volatile anaesthetic con

112 rrigated multipolar linear ablation catheter safely delivers contiguous endocardial or epicardial les

113 awaits SARS-CoV-2 vaccines to be tested and safely deployed, the rapidity with which antiviral monoc

114 There is currently no treatment to safely desensitize mast cells to enable robust allergen

115 entification of low-risk patients who can be safely discharged from the emergency department for outp

116 SA to better understand when patients can be safely discharged.

117 Safely discontinuing PrEP also requires greater understa

118 valuate the ability of vaccine candidates to safely elicit antibodies that bind and neutralize HIV-1.

119 ncreasing the local MTX and hROS levels, and safely eliminating the biocompatible structure from kidn

120 s, computationally inexpensive models can be safely employed to model magnetophoresis.

121 g models to define treatment parameters that safely enabled targeted, noninvasive drug delivery to li

122 vanguard of new immunometabolic adjuvants to safely enhance the efficacy of cancer immunotherapy, rad

123 ed for a standardized, efficient approach to safely evaluate, prepare, and transport patients in need

124 an 2.5 ng/L, do not generally allow users to safely exclude inducible myocardial ischemia.

125 Such information would help to safely expand FUS-BBB opening protocols into a wider ran

126 in Nature, identifying potential methods for safely extracting natural gases stored in naturally occu

127 an [Formula: see text] spin updates and thus safely extrapolate the numerical data both in the thermo

128 Use of an IV push strategy may safely facilitate more rapid administration of beta-lact

129 vise post-neurosurgical patients if they can safely fly.

130 r the intervention effect could be sustained safely for 1 year while reducing pharmacist travel time.

131 apeutic agents into human trials rapidly and safely for COVID-19.

132 TMP-SMZ may be used safely for prophylaxis of recurrent toxoplasmic retinoch

133 intracellular reservoir, where it may reside safely from extracellular stressors prior to causing an

134 with low clinical risk who can be discharged safely from the ED.

135 The new AATP algorithm safely generated ATP sequences and controlled therapy pr

136 ed PAH in two experimental models and can be safely given in combination with currently approved PAH

137 Consequently, such cells continued to safely grow in the presence of antimitotic agents.

138 encing, and response to systemic therapy, to safely guide patients through this cautious recovery pha

139 nd imaging and charge density mapping system safely guided ablation of nonpulmonary vein targets in p

140 able effects, and how these molecules can be safely harnessed for drug development and precursors or

141 The ability to perform APOLT safely has also opened up a range of exciting indication

142 nI assays, an optimized threshold of <5 ng/l safely identified almost one-half of all patients as low

143 utoff after 1-2 wk of treatment allows us to safely identify 41% of the patients who will not benefit

144 The EYEMATE-IO sensor was safely implanted in 22 patients and performed reliably u

145 ring vaccination strategy can be rapidly and safely implemented at scale in response to Ebola virus d

146 ur confidence that audit and feedback can be safely implemented in this setting.

147 The OVIVA trial findings can be safely implemented into clinical practice when patients

148 , only bilevel adiabatic decoupling could be safely implemented.

149 luid IL-1beta and IL-8 could effectively and safely improve antibiotic stewardship in patients with c

150 nds the IL-23 p19 subunit, significantly and safely improved psoriatic arthritis in a phase 2 study.

151 hreshold dose of 13 mug of LSD might be used safely in an investigation of repeated administrations.

152 ons of infectious materials can be performed safely in BSL-2 laboratories within a biological safety

153 rthermore, cataract surgery may be performed safely in eyes with functioning filtering blebs.

154 m saturation allows Hg disc-wells to operate safely in highly concentrated environments at long times

155 ults hint that (18)F-clofarabine can be used safely in humans to measure tissue dCK expression.

156 thoracic MRI examinations, can be performed safely in patients who have non-MRI-conditional devices,

157 the Glissonean pedicle approach was achieved safely in patients with HCC.

158 genetic systems so-encoded should fail more safely in response to most spontaneous mutations.

159 However, until now OBBBO has been achieved safely in subcortical structures, which prevented direct

160 mendations for handling coupling agents more safely in the research laboratory.

161 er blood testing combined with PET-CT can be safely incorporated into routine clinical care, in some

162 e posttransplant function of these organs to safely increase the donor pool, protect these livers aga

163 ion can be a valuable SSI prevention tool to safely increase the proportion of patients receiving BL

164 type II receptors with bimagrumab treatment safely increased skeletal muscle mass but did not improv

165 The new dosing regimen safely increased the efficacy of miltefosine for Eastern

166 -18, exhibit potent antitumor responses, and safely induce complete remissions in patients with leuke

167 Combination therapy with drugs able to safely induce NQO1 in neurons, as well as other brain ce

168 Agents that safely induce, enhance, or sustain multiple innate immun

169 TAA-Ts safely induced disease stabilization, prolonged time to

170 e that an endogenous healing response can be safely induced in tendon by means of biophysical cues us

171 The A/Bethesda/MM1/H3N2 challenge virus safely induced MMID in healthy volunteers, but caused le

172 a-5T4 (MVA-5T4) in mCRC demonstrated that it safely induced serologic and T-cell responses.

173 phoid irradiation and anti-T-cell antibodies safely induces immune tolerance to combined hematopoieti

174 Also, it is unresolved whether DGAT2 can be safely inhibited as a therapy for NAFLD.

175 These biodevices can be safely integrated with biological systems for applicatio

176 I might help determine when treatment can be safely interrupted.

177 and near single-spore sensitivity and can be safely introduced into and recovered from the environmen

178 st two metastatic lesions: one that could be safely irradiated and one measurable by RECIST version 1

179 omatic and presymptomatic cases, in order to safely lift current restrictions and minimize the risk o

180 be used to determine resources needed before safely lifting state policies on social distancing.

181 enervation compared with a sham procedure to safely lower blood pressure in the absence of antihypert

182 In conclusion, allopurinol effectively and safely lowered serum uric acid levels in adults with sta

183 ithm on the basis of the current evidence to safely manage patients with advanced RCC during this pan

184 atients with acute pulmonary embolism can be safely managed as outpatients.

185 velopment goals call for universal access to safely managed sanitation by 2030.

186 osed to better serve those without access to safely managed systems (Target 6.2: universal sanitation

187 "free from contamination" to be defined as "safely managed" (SDG Indicator 6.1.1).

188 iasis is co-endemic and ivermectin cannot be safely mass administered.

189 further development of technologies that can safely measure cortical porosity in vivo.

190 Doffing strategies included doffing safely (minimizing self-contamination) and doffing exped

191 re facilities are largely not using lifts to safely mobilize patients.

192 adapt their locomotion and gaze behaviour to safely negotiate objects in temporally unconstrained sit

193 itigated by developing new therapeutics that safely neutralize anticoagulant activity and inhibit act

194 We demonstrate that FUS can safely, noninvasively, transiently, reproducibly, and fo

195 Whether breast-conservation can be safely offered to BRCA1/2 mutation carriers is debatable

196 scopic surveillance in expert centres can be safely offered to patients who wish to postpone surgery,

197 HIV-1 salvage therapy can safely omit NRTIs without compromising efficacy or durab

198 Drains can be safely omitted for one-quarter of PDs.

199 erse transcriptase inhibitors (NRTIs) can be safely omitted from salvage therapy as long as the regim

200 cRT could be safely omitted in patients with HL presenting with an LN

201 ls to investigate if axillary surgery can be safely omitted in these selected patients when image-gui

202 anetary boundaries within which humanity can safely operate, but is not comprehensively understood.

203 mulate latency reversal more effectively and safely or to prevent viral rebound following ART cessati

204 hat noninvasive ventilation can be delivered safely outside of the ICU, we advocate for hospital-spec

205 e anti-arrhythmic drug levels are reached to safely perform catheter ablation.

206 paroscopic removal of the Linx device can be safely performed as a 1-stage procedure and in conjuncti

207 support the premise that appendectomy can be safely performed as an urgent rather than emergency proc

208 Easy LLRs can be safely performed by most surgeons with minimum expertise

209 This procedure was safely performed in patients with previous augmented Kes

210 require coronary revascularization, IVL was safely performed with high procedural success and minima

211 t of appropriate medical imaging that can be safely performed.

212 We conclude LEN can be administered safely post-allograft in conjunction with AZA, and this

213 Thus, peripheral CB1R blockade may allow safely potentiating the antiobesity and antidiabetic eff

214 enotypic direct-acting antiviral therapy can safely prevent the development of chronic hepatitis C vi

215 rated that IgE-mediated anaphylaxis could be safely prevented in wild-type BALB/c mice by rapid desen

216 iabetes research is to develop treatments to safely promote human ss-cell replication.

217 level expression of antiviral effectors that safely protect them from various viruses.

218 (-)-P7C3-S243 safely protected aging male and female wild-type and TgF

219 w-dose-rate far-UVC exposure can potentially safely provide a major reduction in the ambient level of

220 Junior residents can safely provide on-call triage of patients with symptoms

221 sponse to the COVID-19 pandemic, the need to safely provide patient care meant that many health-care

222 tic target, the function of which can now be safely quantified using non-invasive MRI.

223 s that must be filled in the coming years to safely realize the potential of these novel strategies t

224 infected patients with end organ failure can safely receive an organ transplant from an HIV uninfecte

225 chronic obstructive pulmonary disease could safely receive noninvasive ventilation outside of the IC

226 rs of sepsis are needed to guide measures to safely reduce antimicrobial exposure in this high-risk p

227 c monoclonal antibody that has been shown to safely reduce exacerbations and improve lung function fo

228 pancreas initialised only with body mass can safely reduce mean glycaemia and hypoglycaemia in adults

229 rithm based on blood eosinophil counts could safely reduce systemic corticosteroid exposure in patien

230 healthy volunteers, we found oral Bif195 to safely reduce the risk of small-intestinal enteropathy c

231 Mild hypothermia in the donor safely reduced the rate of delayed graft function in kid

232 on intervals for whole blood donation can be safely reduced to meet blood shortages.

233 in which antibiotic prescribing may be more safely reduced.

234 antisense oligonucleotide successfully, and safely, reduced the CSF concentration of mHTT in individ

235 sVan models accurately predicts BSI risk and safely reduces unnecessary antibiotic use in febrile, no

236 review progress towards the ultimate goal of safely reducing disease activity and preventing damage a

237 Safely reducing red blood cell transfusions can prevent

238 Cow's milk can be successfully and safely reintroduced in a cautious low-dose exclusively h

239 egg-allergic with anti-FcepsilonRIalpha mAbs safely removed >98% of IgE from peritoneal mast cells an

240 GS mice with anti-FcepsilonRIalpha mAbs also safely removed ~98% of mast cell IgE and prevented IgE-m

241 from COVID-19, a key parameter necessary to safely reopen local communities.

242 the editorialists believe that the plan for safely reopening colleges and universities in Taiwan off

243 suggests that, under certain circumstances, safely reopening colleges and universities this fall may

244 feriority, the conventional 6 steps could be safely replaced by a simpler hand hygiene technique.

245 improve health and prevent disease, through safely replacing a large amount of daily sedentary time

246 PI therapy was safely resumed in 89% of patients, although 41% required

247 T pulmonary angiography was not indicated to safely rule out pulmonary embolism.

248 Pulmonary embolism was safely ruled out by the pregnancy-adapted YEARS diagnost

249 stimulation which enables users with SCI to safely stand and exercise.

250 potential of WST-D/NIR therapy as a means of safely stiffening the cornea.

251 rials have studied whether or when women can safely stop screening mammography.

252 ma could be ruled out and asthma medications safely stopped in randomly selected adults with physicia

253 dual fungal lesions to support decisions for safely stopping antifungals.

254 mv anti-FcepsilonRIalpha mAbs more safely suppress IgE-mediated anaphylaxis and food allerg

255 TUS safely suppressed TMS-elicited motor cortical activity,

256 axis, while a rapid desensitization approach safely suppresses disease in mice with increased suscept

257 ggest that HSP70-mediated degradation can be safely targeted with domperidone to rescue ER-retained A

258 igate the molecular mechanism of disease and safely test novel therapies for LCA4 in vitro.

259 mmitted to ensuring that FMT products can be safely tested in clinical trials.

260 managing GM1 gangliosidosis potentially more safely than with gene therapy approaches.

261 elative their body size and form to navigate safely through complex environments.

262 arranted to examine whether KE could be used safely to have longer-term effects on metabolic control.

263 ster the most effective therapy patients can safely tolerate.

264 CAM2038 weekly, 24 and 32 mg, was safely tolerated and produced immediate and sustained op

265 gests that telomerase activation is not only safely tolerated but also advantageous for clonal expans

266 olunteers (n = 192 and n = 81), subjects who safely took potentially hepatotoxic drugs without advers

267 In order to safely translate this approach to humans, a more in-dept

268 ally improved our ability to effectively and safely treat chronic inflammatory diseases.

269 gned to provide practical guidance on how to safely treat patients with this therapy.

270 ion of therapeutics within the epidermis can safely treat skin inflammation, scaling, and erythema as

271 tation does not identify patients who can be safely treated with rFVIII, as relates to immunogenicity

272 er outcomes than LNJSA and may be able to be safely treated with shorter antimicrobial courses.

273 atients receiving deep brain stimulation may safely undergo 1.5- and 3-T MRI.

274 suggest that blood collection services could safely use shorter donation intervals and more intensive

275 udy demonstrate that CMV-specific ACT can be safely used as an adjuvant therapy for primary GBM and,

276 presented here illustrate that UHRA could be safely used as an antidote during adverse therapeutic mo

277 Regadenoson is well tolerated and can be safely used for cardiac MRI stress tests.

278 gues and CpG oligodeoxynucleotides have been safely used in clinical trials, our study supports combi

279 As fasudil has been safely used in humans, our results suggest that it could

280 ICMA is effective and can be safely used in patients with well-controlled diabetes, w

281 may provide some reassurance that IPT can be safely used in the second or third trimester of pregnanc

282 lts provide some reassurance that IPT can be safely used in the second or third trimester of pregnanc

283 e pharmacological PKCeta inhibition could be safely used in vivo to inhibit undesired contact-depende

284 n the multi-microsecond timescale and can be safely used to reproduce global structure of DNA duplexe

285 ological systems before such products can be safely utilized in humans.

286 parameters under which this can be performed safely, whereby the BBB is disrupted to the point of bei

287 ry barriers in the tumor microenvironment to safely widen the therapeutic window of a nanoformulated

288 These patients were able to walk safely with 65-70% body weight support, accumulating a t

289 Hiatal hernia repair can be performed safely with a low incidence of complications.

290 e suggests that IOL implantation can be done safely with acceptable side effects in children older th

291 RVX208 could be combined safely with contemporary PAH standard of care.

292 , we demonstrate that RAMIE can be performed safely with excellent oncologic outcomes and decreased h

293 d pancreatic adenocarcinoma can be performed safely with limited mortality and morbidity.

294 ated protein 4) inhibitor, could be combined safely with microwave ablation to enhance the effect of

295 ntravascular filter fragments can be removed safely with success rates that vary according to locatio

296 ipants need an informed approach for working safely with the etiological agent, the novel human coron

297 Although studies indicate that Tac can be safely withdrawn in a subset of kidney transplant recipi

298 n KTx is necessary, immunosuppression can be safely withhold in case of same donor for both grafts an

299 ogrammed to manufacture and deliver products safely without interference from the host genome.

300 Intravitreal injection can be given safely without pre-operative and post-operative antibiot