ライフサイエンスコーパス: scoliosis

1 derlying heart defect, surgical history, and scoliosis.

2 heir age, skeletal immaturity, and degree of scoliosis.

3 fragmented in some juveniles with idiopathic scoliosis.

4 cant weakness, respiratory insufficiency, or scoliosis.

5 rgery in patients with adolescent idiopathic scoliosis.

6 sion for patients with adolescent idiopathic scoliosis.

7 camptocormia, antecollis, Pisa syndrome, and scoliosis.

8 sis (HGPPS), a rare disease marked by severe scoliosis.

9 ssful in all but one patient, who had severe scoliosis.

10 ine, such as those observed in patients with scoliosis.

11 on and treatment of patients with idiopathic scoliosis.

12 ties, weight changes, hind limb atrophy, and scoliosis.

13 and small joint laxity and early progressive scoliosis.

14 ght than normal littermates and many develop scoliosis.

15 in infancy, early spinal rigidity, and early scoliosis.

16 of girls and 0.3% of boys) were treated for scoliosis.

17 had Marfan's disease, and one had congenital scoliosis.

18 mented medical or chiropractic evaluation of scoliosis.

19 Most commonly seen is idiopathic scoliosis.

20 ed craniofacial defects, heart anomalies and scoliosis.

21 penia, recurrent fracture of long bones, and scoliosis.

22 als also displayed peripheral neuropathy and scoliosis.

23 ne protein also associated astrogliosis with scoliosis.

24 diagnosis of cortical visual impairment and scoliosis.

25 formation defects as well as idiopathic-like scoliosis.

26 brain malformations, muscular hypotonia, and scoliosis.

27 ated with coronal asymmetry in those without scoliosis.

28 ng of the aetiology of adolescent idiopathic scoliosis.

29 vioral abnormalities, Marfanoid habitus, and scoliosis.

30 mnasts and to develop a model for predicting scoliosis.

31 lt spines with misshapen vertebral bones and scoliosis.

32 corrective surgery in patients who developed scoliosis.

33 lts are iatrogenic flatback and degenerative scoliosis.

34 d, with implications for understanding human scoliosis.

35 survival or quality of life indicators, like scoliosis.

36 hondral bone formation and subsequent severe scoliosis.

37 uman plays an important role in induction of scoliosis.

38 osteocyte function in adolescent idiopathic scoliosis.

39 ings, are prone to 3D deformation leading to scoliosis.

40 gularities, and vertebral anomalies, such as scoliosis.

41 , and horizontal gaze palsy with progressive scoliosis.

42 ition, provide new opportunities to evaluate scoliosis.

43 d how defects in those processes may lead to scoliosis.

44 therapeutic intervention may prevent severe scoliosis.

45 eptibility has been implicated in congenital scoliosis.

46 characteristic of TBX6-associated congenital scoliosis.

47 mutation is insufficient to cause congenital scoliosis.

48 dactyly of the hands, vertebral fusions, and scoliosis.

49 D PARTICIPANTS: The Adult Symptomatic Lumbar Scoliosis 1 (ASLS-1) study was a multicenter, prospectiv

50 inesia patients is not fully associated with scoliosis [10, 11], other pathogenic mechanisms remain t

51 in the 161 persons with sporadic congenital scoliosis (11%); we did not observe any null mutations i

52 Han Chinese persons with sporadic congenital scoliosis, 166 Han Chinese controls, and 2 pedigrees, fa

53 cardiomyopathy (5), developmental delay (4), scoliosis (3), epilepsy (3) and hearing-difficulties (2)

54 keletal abnormalities were common, including scoliosis (64%), arthrogryposis (33%) and foot deformiti

55 There was a high rate of scoliosis (81%), scoliosis surgery (36%), and walking di

56 nction in vitro Adult Myh3 null mice exhibit scoliosis, a characteristic phenotype exhibited by indiv

57 entricles is associated with idiopathic-like scoliosis across diverse genetic models.

58 study found that major depressive disorder, scoliosis, acute appendicitis with peritonitis, asthma,

59 atric diseases, including adult degenerative scoliosis (ADS).

60 Minor residual scoliosis after fusion does not adversely affect outcome

61 Adolescent idiopathic scoliosis (AIS) affects 1-3% of children in the at-risk

62 Adolescent idiopathic scoliosis (AIS) affects 3% to 4% of children between the

63 Adolescent idiopathic scoliosis (AIS) affects around 3% of the general populat

64 Adolescent idiopathic scoliosis (AIS) and pectus excavatum (PE) are common ped

65 Adolescent idiopathic scoliosis (AIS) causes spinal deformity in 3% of childre

66 Adolescent idiopathic scoliosis (AIS) is a common and progressive spinal defor

67 Adolescent idiopathic scoliosis (AIS) is a complex inherited spinal deformity

68 Adolescent idiopathic scoliosis (AIS) is a complex spine deformity, affecting

69 Adolescent idiopathic scoliosis (AIS) is a prevalent spinal deformity occurrin

70 Adolescent idiopathic scoliosis (AIS) is a three-dimensional (3D) deformity of

71 Adolescent idiopathic scoliosis (AIS) is an unexplained and common spinal defo

72 Adolescent idiopathic scoliosis (AIS) is the most common form of spinal deform

73 Adolescent idiopathic scoliosis (AIS) is the most common spinal deformity affe

74 Adolescent idiopathic scoliosis (AIS) is the most prevalent pediatric spinal d

75 Moderate-grade adolescent idiopathic scoliosis (AIS) may be treated with full-time bracing.

76 formity progression in adolescent idiopathic scoliosis (AIS) remain poorly understood.

77 Adolescent idiopathic scoliosis (AIS), a sideways curvature of the spine, is t

78 that observed in human adolescent idiopathic scoliosis (AIS).

79 r posterior fusion for adolescent idiopathic scoliosis, although outcomes are adversely affected if p

80 ith idiopathic, congenital, or neuromuscular scoliosis and 41 matched controls of the same sex and ap

81 es of 76 Han Chinese persons with congenital scoliosis and a multicenter series of 42 persons with 16

82 tients who undergo surgery for correction of scoliosis and craniofacial anomalies should have serum m

83 the most common cause of mortality, and also scoliosis and diabetes.

84 joint contractures at birth and progressive scoliosis and fractures, but there is remarkable variabi

85 ost common phenotypes included thoracolumbar scoliosis and gait disturbance.

86 three with hip dysplasia, and one with both scoliosis and hip dysplasia.

87 The rapidly developing scoliosis and its associated pelvic obliquity can even c

88 that Nf1(Col2)(-/-) mice display progressive scoliosis and kyphosis, tibial bowing and abnormalities

89 advances in understanding tibial dysplasia, scoliosis and malignant peripheral nerve sheath tumors.

90 al-dominant SMD characterized by significant scoliosis and mild metaphyseal abnormalities in the pelv

91 l dysplasias characterized by a short trunk, scoliosis and mild short stature.

92 udy aimed to examine the association between scoliosis and musculoskeletal characteristics in young f

93 Scoliosis and pectus excavatum were significantly more p

94 ubset of control subjects were evaluated for scoliosis and pectus excavatum.

95 cting the cervical and dorso-lumbar regions, scoliosis and respiratory insufficiency.

96 eletal manifestations, such as osteoporosis, scoliosis and short statures.

97 Respiratory failure was common and scoliosis and spinal rigidity were significant in some o

98 hyseal injuries; breast and pelvic injuries; scoliosis and spondylolysis; multidirectional shoulder i

99 ate treatment of fractures, the treatment of scoliosis and the use of intramedullary rods.

100 t careful attention be paid to screening for scoliosis and tibial dysplasia.

101 Dystrophic scoliosis and tibial pseudoarthrosis are the most severe

102 uctural anomalies such as spondylolisthesis, scoliosis and vertebral segmentation anomalies and previ

103 n with a slender body morphotype, often with scoliosis and/or pectus excavatum.

104 93.8%), foot deformities (n = 11, 84.6%) and scoliosis and/or rigid spine (n = 12, 80%).

105 itional fusions between skeletal structures, scoliosis, and altered cartilage in the intervertebral j

106 phenotype of developmental delay, hypotonia, scoliosis, and cerebellar atrophy in three families.

107 nditions characterized by multiple pterygia, scoliosis, and congenital contractures of the limbs.

108 arpal/tarsal coalition, conductive deafness, scoliosis, and craniosynostosis.

109 , previous thoracotomy/ies, body mass index, scoliosis, and diaphragm palsy.

110 haracterized by camptodactyly, tall stature, scoliosis, and hearing loss (CATSHL syndrome) to chromos

111 s, variable skeletal abnormalities including scoliosis, and hepatic and renal involvement, including

112 inal problems, including kyphosis, lordosis, scoliosis, and hypoplasia.

113 cal manifestations of horizontal gaze palsy, scoliosis, and intellectual disability.

114 phy predominantly of the distal lower limbs, scoliosis, and mild distal sensory involvement.

115 cases can cause spinal deformities, such as scoliosis, and result in disability and distress of affe

116 yposis (DA) who had congenital contractures, scoliosis, and short stature.

117 83) likely to have spontaneous pneumothorax, scoliosis, and striae but were comparable in revised Ghe

118 astia, cleft palate/bifid uvula, progressive scoliosis, and structural brain abnormalities.

119 In contrast, cartilage overgrowth and scoliosis are absent in rare viable nkx3.2 knockdown ani

120 screening programs for adolescent idiopathic scoliosis are mandated in 26 states in the United States

121 Although Pisa syndrome and scoliosis are sometimes used interchangeably to describe

122 xhibited stereotypical positioning of limbs, scoliosis, arthrogryposis, pulmonary hypoplasia, and res

123 velopmental abnormalities such as congenital scoliosis as well as diseases such as T-cell acute lymph

124 rative treatment of adult symptomatic lumbar scoliosis (ASLS) are needed to assess benefits and durab

125 7 days postfertilization, the same time when scoliosis became apparent and prior to multiciliated epe

126 ration pre- and intraoperatively, or type of scoliosis between those who developed SIADH and those wh

127 oration of cilia motility after the onset of scoliosis blocks spinal curve progression.

128 g identified 5 of the 9 children treated for scoliosis but resulted in referrals for another 87 child

129 bone mineral density (BMD) in patients with scoliosis by using quantitative computed tomography (QCT

130 ificant medical morbidity and deformity that scoliosis can insidiously inflict.

131 nificant p-values for most of the idiopathic scoliosis candidate loci, and for some loci, the estimat

132 f TBX6 accounted for up to 11% of congenital scoliosis cases in the series that we analyzed.

133 as a novel pathogenic mechanism of zebrafish scoliosis caused by cilia dysfunction.

134 ic manifestations of Marfan syndrome include scoliosis, chest wall deformity, dural ectasia, joint hy

135 by severe intellectual disability, epilepsy, scoliosis, choreoathetosis, dysmorphic facial features a

136 ent = -13.53), who more often develop severe scoliosis compared to those classified in the other two

137 with osteopenia, severe osteoarthritis, and scoliosis compared with previously described techniques.

138 ance: Horizontal gaze palsy with progressive scoliosis, Congenital mirror movements, and Congenital f

139 Surgical management of idiopathic scoliosis continues to evolve, and now a thoracoscopic e

140 ervative Treatment for Adolescent Idiopathic Scoliosis (CONTRAIS) randomized clinical trial was condu

141 patients with SMA-II undergoing surgery for scoliosis correction.

142 t rank, 19; prevalence rank, 10; ICC, 0.49), scoliosis (cost rank, 6; prevalence rank, 38; ICC, 0.27)

143 Scoliosis, coxa vara, childhood cataracts, short dental

144 Skeletal defects include kyphosis, scoliosis, crooked tails and curvature and overgrowth of

145 ificant health problems including congenital scoliosis (CS) and recurrent organ system malformation s

146 Congenital scoliosis (CS) is a complex genetic disorder characteriz

147 Congenital scoliosis (CS) is a type of vertebral malformation for w

148 es caused by malformed vertebrae (congenital scoliosis (CS)) are apparent at birth.

149 n frontal radiographs and the measurement of scoliosis curves as important tools in the management of

150 Scoliosis developed in 19 (25%) patients; 6 patients req

151 d Annexin levels as a potential mechanism of scoliosis development in rpgrip1l juveniles.

152 Predicting scoliosis development in young gymnasts can be important

153 identify variables associated with survival, scoliosis development, and need for corrective scoliosis

154 Variables correlated with survival, scoliosis development, or need for corrective surgeries

155 tion, and tumor size are not associated with scoliosis development.

156 hypertriglyceridemia, hypercholesterolemia, scoliosis, developmental delay and pulmonary and urologi

157 In children with spinal cord injury (SCI), scoliosis due to trunk muscle paralysis frequently requi

158 e report zebrafish ccdc57 mutants exhibiting scoliosis during late development, similar to that obser

159 cles, progressive joint contractures, severe scoliosis, elevated serum creatine kinase level, myopath

160 ing the growing rod treatment in early-onset scoliosis (EOS) and identify the risk factors of sagitta

161 several were much more common and included: scoliosis from bony overgrowth (94%), pulmonary venous d

162 alizations, inability to walk, bradykinesia, scoliosis, gastrostomy feeding, age of seizure onset, an

163 Only a quarter of patients with structural scoliosis had evidence of bony fusion on the side of the

164 ron distribution and metabolism and frequent scoliosis have also been associated with an allele of in

165 Prognostic indicators for juvenile scoliosis have been identified.

166 Previous long-term studies of idiopathic scoliosis have included patients with other etiologies,

167 cause horizontal gaze palsy with progressive scoliosis (HGPPS), a rare disease marked by severe scoli

168 ed in horizontal gaze palsy with progressive scoliosis (HGPPS).

169 with horizontal gaze palsy with progressive scoliosis (HGPPS).

170 Other conditions such as scoliosis, hip instability, patellar instability and foo

171 ly, short stature, mild spasticity, thoracic scoliosis, hyperextendable MCP joints, rocker-bottom fee

172 nd 9 conditions had an ICC higher than 0.20 (scoliosis: ICC, 0.27; hypertrophy of tonsils and adenoid

173 There was hearing loss in 21 and scoliosis in 17.

174 present in 5.4%, Marfan syndrome in 1.1% and scoliosis in 29%.

175 t with the emergence of axial curvatures and scoliosis in adult animals.

176 togenesis defects associated with congenital scoliosis in amniotes.

177 We demonstrate that the scoliosis in dstyk mutants is related to the wavy and ma

178 e defect in notochord vacuole biogenesis and scoliosis in dstyk mutants.

179 Adolescent idiopathic scoliosis in humans is often associated with vestibulomo

180 the impact of primary myopathy on idiopathic scoliosis in mice and man.

181 The severe scoliosis in most individuals and rare developmental cox

182 of Ptk7 in motile ciliated lineages prevents scoliosis in ptk7 mutants, and mutation of multiple inde

183 ruled out Urp1/2 levels as a main driver of scoliosis in rpgrip1 mutants.

184 raising the possibility that it may underlie scoliosis in SMA patients.

185 sufficient to generate vertebral fusions and scoliosis in the adult spine.

186 The cumulative incidence of diagnosed scoliosis in this population was 1.8% (95% confidence in

187 ystem, and its disruption has been linked to scoliosis in zebrafish [1, 2].

188 rity defects are one of the earliest sign of scoliosis in zebrafish and disclose the essential and co

189 Cilia defects lead to scoliosis in zebrafish, but the underlying pathogenic me

190 hyperextensible joints (in 68 percent), and scoliosis (in 76 percent of patients 16 years of age or

191 The finding of 'structural scoliosis' in Pisa syndrome should not preclude interven

192 eous conclusion that all types of idiopathic scoliosis inevitably end in disability.

193 dicate a neuropathic origin for "idiopathic" scoliosis, involving the dysfunction of synaptic neurotr

194 Congenital scoliosis is a common type of vertebral malformation.

195 Adolescent idiopathic scoliosis is a complex disease with unclear etiopathogen

196 Scoliosis is a complex genetic disorder of the musculosk

197 Congenital scoliosis is a deformity of the developing spine that re

198 Idiopathic scoliosis is a diagnosis of exclusion and the approach t

199 Scoliosis is a disease estimated to affect more than 8%

200 Idiopathic scoliosis is a lateral curvature of the spine greater th

201 tection and close surveillance of congenital scoliosis is critical, as a rapidly progressive curve ma

202 ibes a patient who lists to the side whereas scoliosis is defined by spinal curvature and rotation an

203 Scoliosis is described as a lateral curvature of the spi

204 Idiopathic scoliosis is more clearly understood recently and is rec

205 Scoliosis is more common in patients with missense mutat

206 onal asymmetry of the spine in those without scoliosis is related to features of spinal sagittal shap

207 Adolescent idiopathic scoliosis is the most prevalent spine deformity and the

208 Scoliosis is traditionally evaluated by measuring the Co

209 Idiopathic scoliosis (IS) affects 3% of children worldwide, yet the

210 Idiopathic scoliosis (IS) is a common paediatric musculoskeletal di

211 Idiopathic scoliosis (IS) is a complex 3D deformation of the spine

212 Idiopathic scoliosis (IS) is a complex pediatric disease of unknown

213 Idiopathic scoliosis (IS) is a spine deformity that affects approxi

214 Idiopathic scoliosis (IS) is the deformation and/or abnormal curvat

215 Idiopathic scoliosis (IS) is the most common spinal deformity diagn

216 Idiopathic scoliosis (IS) is the most common spinal deformity in ch

217 underlying vertebral abnormality (idiopathic scoliosis (IS)) most commonly manifest during adolescenc

218 in which the spine curves abnormally such as scoliosis, kyphosis, and lordosis.

219 characterized by skeletal defects including scoliosis, large epiphyses, wide growth plates and super

220 f notochord vacuoles and a severe congenital scoliosis-like phenotype in zebrafish.

221 E) of the notochord, and detected congenital scoliosis-like vertebral malformations (CVMs).

222 Late-onset idiopathic scoliosis (LIS) is a distinct entity with a unique natur

223 ) surface topography images of those without scoliosis, measures of coronal asymmetry, along with mea

224 a median follow-up of 5 years, 13% developed scoliosis (median Cobb angle 26) and 5% required correct

225 progression of axial curvatures in distinct scoliosis mutant zebrafish models.

226 In those patients with scoliosis necessitating treatment, bracing should be the

227 zed by slowly progressive or non-progressive scoliosis, neck and spine contractures, hypotonia and re

228 Nineteen had idiopathic scoliosis, nine had neuromuscular scoliosis, one had Mar

229 Scoliosis occurs in 13% of patients, but patient-reporte

230 an adult man with a gracile build and severe scoliosis of the thoracic spine.

231 All patients had scoliosis on standing radiographs, and 12 had scoliosis

232 idiopathic scoliosis, nine had neuromuscular scoliosis, one had Marfan's disease, and one had congeni

233 c and rhombencephalic ventricles just before scoliosis onset and increasing with time in severity.

234 Here, we dissected the mechanisms of scoliosis onset in a zebrafish mutant for the rpgrip1l g

235 ch encompass contractures of hands and feet, scoliosis, ophthalmoplegia, and ptosis.

236 abnormalities of the thoracic cage, such as scoliosis or flail chest, interfere with the action of t

237 specifics (e.g. to decide whether this is a scoliosis or sagittal imbalance) and assess its extend,

238 ssues include electrocardiographic findings, scoliosis, osteopenia, and motor control.

239 was found between idiopathic and congenital scoliosis patients (p > 0.05).

240 gilant monitoring and thorough evaluation of scoliosis patients can steer patients toward appropriate

241 compare the BMD of idiopathic and congenital scoliosis patients.

242 ll and lean body habitus and higher rates of scoliosis, pectus excavatum, mitral valve prolapse, and

243 Anti-inflammatory drug treatment reduced scoliosis penetrance and severity and this correlated wi

244 coliosis on standing radiographs, and 12 had scoliosis persisting in the supine position.

245 numerous ciliary genes are associated with a scoliosis phenotype, among ciliopathies and knockout ani

246 They can cause scoliosis, pressure on the neighboring lung parenchyma a

247 nts, this network may be used for monitoring scoliosis progression in patients.

248 Scoliosis progression is influenced by growth rate, but

249 onserved roles of Urotensin signaling during scoliosis progression.

250 Sim2 mutants also develop congenital scoliosis, reflected by the unequal sizes of the left an

251 Although the etiology of idiopathic scoliosis remains unclear, there continues to be a searc

252 The primary cause of scoliosis remains unknown.

253 mean age 15.5 [11-26] years) with late-onset scoliosis requiring corrective surgery were enrolled.

254 were the Oswestry Disability Index (ODI) and Scoliosis Research Society 22 (SRS-22) at 2-, 5-, and 8-

255 increased frequency of perinatal mortality, scoliosis, resting tremors and ptosis.

256 Egr3-/- mice develop gait ataxia, scoliosis, resting tremors, and ptosis, suggesting a def

257 ded early onset axial and proximal weakness, scoliosis, rigid spine, dysmorphic facies, cutaneous inv

258 In this population, school scoliosis screening identified some children who went on

259 sidered in making decisions regarding school scoliosis screening.

260 ), sex (P = .83), body mass index (P = .63), scoliosis severity (P = .44), or image type (low-dose st

261 eir haplotypes with plasma YKL-40 levels and scoliosis severity as a function of their classification

262 Scoliosis severity in AIS cases was associated with FBN1

263 exclusion and the approach to a patient with scoliosis should aim toward ruling out other possible ca

264 ms, Pediatrics, Machine Learning Algorithms, Scoliosis, Spine Supplemental material is available for

265 otential amplitude, and in the prevalence of scoliosis, suggesting the possibility of a milder phenot

266 There was a high rate of scoliosis (81%), scoliosis surgery (36%), and walking difficulty (94%) am

267 everal medical complications can occur after scoliosis surgery in children and adolescents.

268 ticularly pulmonary complications related to scoliosis surgery, embolic complications of joint arthro

269 to recent literature specifically related to scoliosis surgery.

270 oliosis development, and need for corrective scoliosis surgery.

271 ts are time-consuming, limiting their use in scoliosis surgical planning and postoperative monitoring

272 Each participant was identified for scoliosis suspected status (Adam's test and scoliometer)

273 istic regression model for the prediction of scoliosis suspected status in gymnasts using age, bone s

274 The scoliosis suspected status was associated with hyperlaxi

275 The scoliosis suspected status was highly prevalent in young

276 ifferences between gymnasts with and without scoliosis suspected status were found in range of motion

277 ts revealed that 79/274 (28.8%) gymnasts had scoliosis suspected status without a significant differe

278 d, and low bone strength are associated with scoliosis suspected status, while menarche and pubertal

279 and skeletal symptoms, including progressive scoliosis, that did not conform to standard diagnostic c

280 s them at risk for functional impairment and scoliosis, these patients are also at significant risk f

281 als presented with hearing loss, eleven with scoliosis, three with hip dysplasia, and one with both s

282 iographs obtained in patients with suspected scoliosis to automatically measure Cobb angles.

283 using zebrafish have linked idiopathic-like scoliosis to irregularities in motile cilia-mediated cer

284 ng program for the identification of treated scoliosis was 0.05 (95% CI, 0.048-0.052), with 448 child

285 Scoliosis was associated with posterior rib resection (H

286 Scoliosis was noted in 28% (340).

287 Studies with instrumentation and scoliosis were excluded.

288 Twenty-two of the patients with scoliosis were idiopathic, 15 were congenital, four were

289 The mean BMD values of patients with scoliosis were significantly lower compared with the con

290 rtebral body BMD values of the patients with scoliosis were significantly lower than those seen in th

291 olinium studies and studies of patients with scoliosis, were excluded.

292 pinal curves of adolescents with and without scoliosis, were generated.

293 be exposed to increased radiation, that is, scoliosis, where level of radiation exposure is known.

294 ents who had undergone laminectomy developed scoliosis, whereas spinal deformities were only detected

295 syndactyly, clinodactyly, cleft palate, and scoliosis, which, together with cardiodysrhythmic period

296 acing in patients with adolescent idiopathic scoliosis who are at risk for curve progression and even

297 involving additional persons with congenital scoliosis who carried a deletion affecting TBX6 confirme

298 atropic dysplasia present with a progressive scoliosis, widespread metaphyseal involvement of the app

299 llmarks of AIS, including postnatal onset of scoliosis without malformations of vertebral units.

300 Among patients who develop scoliosis, younger patients are more likely to require c