ライフサイエンスコーパス: scope

1 d it offers significantly expanded substrate scope.

2 lead to detonation and suffered from limited scope.

3 the best ancestors but exhibits an unrivaled scope.

4 n a targeted workflow, which can limit their scope.

5 hows high atom economy and a broad substrate scope.

6 reactions, and function only within a narrow scope.

7 methodology showed good yields and substrate scope.

8 ey composition represent a challenge to this scope.

9 re need to be explored in a broader material scope.

10 definitional clarity and their overly broad scope.

11 pment of site-selective catalysts with broad scope.

12 computationally intensive or have a limited scope.

13 rtners of 2-oxindoles with a broad substrate scope.

14 The SCOPE 2 trial (Safety and Efficacy Comparison of Two TAV

15 SCOPE 2 was a randomized trial performed at 23 centers i

16 gional input-output (GMRIO) model to develop scope 3 emission reduction targets for individual econom

17 l partnerships for utilities, accounting for scope 3 emissions of utilities, and being open to extend

18 ivity, use of expensive oxidants and limited scope(6-13).

19 are EMR technique utilizing a novel over the scope additional accessory channel, termed EMR Plus (EMR

20 A novel external over-the-scope additional working channel (AWC) (Ovesco, Tuebinge

21 ial review will outline examples showing the scope, advantages and pitfalls of using internal catalys

22 y hypothesis-testing toolkit, limiting their scope and application.

23 We aimed to describe the national scope and associated tradeoffs of financial hardship fro

24 tocol is distinguished by its wide substrate scope and broad applicability, even in the context of la

25 The process shows broad substrate scope and delivers complex, chiral homopropargyl amines;

26 gineering applications, vastly enhancing the scope and efficiencies of genetic editing and transcript

27 asic conditions that can sometimes limit the scope and efficiency of [(18)F]fluoride incorporation ch

28 al route toward pyrrolocarbazoles with broad scope and functional group tolerance.

29 The reaction proceeds with a broad substrate scope and good functional group compatibility.

30 This method features a broad substrate scope and good functional group tolerance, and the in si

31 n and spirocyclization showed wide substrate scope and good functional group tolerance.

32 pplicable method featuring a broad substrate scope and high functional group tolerance remains elusiv

33 A wide substrate scope and high functional group tolerance were observed

34 ve been constructed efficiently with a broad scope and high functional group tolerance.

35 , and imply that a full understanding of the scope and impact of dust-mediated processes will require

36 Third, we need to define the scope and importance of potential responses across level

37 iting capabilities, expanded their targeting scope and improved editing specificity.

38 ed transcriptomics approaches to compare the scope and kinetics of the host response to the wild-type

39 Theoretical support to the mechanism and the scope and limitation of the reaction are discussed.

40 These mechanistic insights delineate the scope and limitations of S1-chaperoned unfolding of stru

41 The scope and limitations of the reaction were explored, wit

42 eview recent developments to demonstrate the scope and limitations of this interesting and versatile

43 lts of our systematic investigation into the scope and limitations of this process and have identifie

44 The optimization and scope and limitations of this short and general sequence

45 This study significantly expands both the scope and method of identification for construction of a

46 What makes this pandemic notable is that the scope and number of reported cases have been primarily i

47 ddressing these hypotheses remain limited in scope and number.

48 ionic, etc.) natures have proven their wide scope and opportunities.

49 n order to address basic questions about the scope and power of the group identity explanation.

50 The reaction proved to be general in scope and proceeds through a triple domino process.

51 tions are described that expand the reaction scope and provide for mild temperatures (T >= 60 degrees

52 The scope and regioselectivity of the reaction are presented

53 d I-band and H-zone models with unparalleled scope and resolution.

54 les were devalued, and others had increasing scope and responsibility.

55 nt: HEM modeling, including model structure, scope and scale, demographics, time horizons, counterfac

56 t, which substantially expanded the reaction scope and significantly improved the enantioselectivity

57 de, optimization of reaction parameters, the scope and simplification of its implementation through i

58 rative approach to test hypotheses about the scope and strength of convergence in a marine fish clade

59 ted; subordinated task-doers; and broadening scope and strengthened identity.

60 tion of this transformation to establish its scope and synthetic utility.

61 lustrative examples that highlight substrate scope and the application of titanium catalysis to the s

62 From the broad substrate scope and the high enzymatic enantioselectivity of LeuDH

63 lecular-weight control, CTA functional group scope, and accessible polymer architectures.

64 tional simplicity, mild conditions and broad scope, and allows for the synthesis of highly functional

65 tous and inexpensive reagents, boasts a wide scope, and can be made highly atom economic, makes this

66 advantages but also stereochemical aspects, scope, and limitations, in particular side reactions, ar

67 merging, but they are limited in complexity, scope, and scalability.

68 er mild reaction conditions, display a broad scope, and show excellent functional group tolerance.

69 The method has a reasonable substrate scope, and the products are formed in 50-70% yields.

70 he features, reaction selectivity, substrate scopes, and limitations of the approaches.

71 (SARDs) and pan-antagonists that exert broad-scope AR antagonism.

72 unclear due to traditional MS models' narrow scope around a limited number of cell-cycle regulation b

73 ing behavior from that of 2, affecting guest scope as well as binding affinities.

74 t studies is limited by the small geographic scope as well as limited breadth and integration of meas

75 Both species exhibited decreases in aerobic scope (as a function of reduced maximum metabolic rate)

76 The reaction has a broad scope, as demonstrated by the synthesis of 35 different

77 ion's progress in combatting poverty, PSID's scope broadened quickly to a variety of topics and field

78 Herein, we expand this scope by utilizing phytic acid-doped polyaniline as a no

79 se examples usually possess limited property scope, can be difficult to process, and are non-responsi

80 CTICE ADVICE 5: Hemostasis using an over-the-scope clip should be considered in select patients with

81 o, FAAH exhibits a more restricted substrate scope compared to PM20D1.

82 sure on healthy and prediabetic individuals (SCOPE)] conducted in Beijing between August 2013 and Feb

83 aign scenarios that differed in geographical scope, coverage, and rollout duration.

84 The synthetic strategy is efficient and the scope covers a variety of functional groups.

85 istry since 2010 with a focus on the general scope, current limitations, stereochemical reaction cont

86 These advances in scope enable independent regulations of many desired pho

87 The reactivity is broad in scope, enabling the copolymerization of highly functiona

88 to generate guidance for modeling studies on scoping, estimating, and reporting population health eff

89 ion from aldehydes and ketones, the reaction scope for 3,6-bis(thiomethyl)-1,2,4,5-tetrazine, a surve

90 , scalability to the gram scale, and a broad scope for both aromatics and halogens.

91 ith an innate-like biology, albeit with some scope for clonal amplification.

92 The scope for data annotation has been substantially expande

93 This method has a general scope for detecting a broad range of redox active and no

94 protective treatments in this population and scope for further benefits if use of these treatments is

95 s of the existing protocols and the possible scope for future development are also discussed.

96 iderably simplifies and extends the modeling scope for granular dynamics, with potential applications

97 m 38.38 min/day), which may have limited the scope for improvement.

98 Furthermore, the scope for plasticity resulting from warm acclimation dec

99 Our approach has scope for point-of-care clinical application to aid in t

100 lytic methodology displays a broad substrate scope for the N-alkylation of aromatic and heteroaromati

101 is new versatile methodology provides a wide scope for the synthesis of different functionally substi

102 ctory mechanical properties have limited the scope for wider applications of these exciting materials

103 gressed the drag coefficients for wind speed scope from 10 ms(-1) to 28 ms(-1).

104 oles were synthesized with a broad substrate scope from the reaction of cyclic 1,3-dienyl boronic est

105 al-free one-pot synthesis, broader substrate scope, good-to-excellent yields, use of cost-effective a

106 Diverse substrate scope has been demonstrated with 48 different examples w

107 The reaction exhibits a broad substrate scope, has high functional-group tolerance, and can be e

108 tolerance and an immense array of substrate scope have been explored with the successful synthesis o

109 efficient, highly regioselective, and broad-scope hydration method that is facilitated by an unusual

110 ar biology and mechanobiology illustrate the scope, impact and potential of nanomechanical mapping me

111 Moderate reaction conditions, a large scope in experiment design for selective reactions, easy

112 his flow process enables a broader substrate scope, including less-activated (hetero)aryl bromides an

113 Substrate scope is documented and the role of base in the C-C bond

114 Reaction optimization, substrate scope, mechanistic features, and synthetic applications

115 A discussion of the reaction scope, mechanistic insights, and synthetic applications

116 Single-cell proteomics by mass spectrometry (SCoPE-MS) is a recently introduced method to quantify mu

117 Pomeranz-Fritsch protocol, which expands the scope of 1,2-dihydroisoquinoline (DHIQ) products.

118 n fruit flies, significantly expanding their scope of action.

119 esults invite us to reconsider the range and scope of actions achievable by large groups, and to expl

120 al synapses encourages a reassessment of the scope of activity-dependent pH influences on neurotransm

121 The scope of adaptive phenotypic change within a lineage is

122 This protocol is accepting of a broad scope of alkene and carboxylic acids, including challeng

123 couples (hetero)aromatic esters with a broad scope of amines to form (hetero)aryl amine products.

124 more focused ligand spectrum can expand the scope of application of such metabolite sensors.

125 ependent acquisition (DIA) and extending its scope of application.

126 imum throughput performance and broadens the scope of applications for this emerging technique.

127 on between small protein domains have a wide scope of applications, from using as a molecular anchora

128 t that global warming will limit the aerobic scope of aquatic ectotherms and may place a greater meta

129 and active metabolic rate and hence aerobic scope of aquatic ectotherms.

130 This reactivity paradigm, which broadens the scope of aryl donor partners to homoenolates, allows ope

131 or microbial tropism changes and expands the scope of biological C1 conversion.

132 ie a consequence or causal effect within the scope of biological functionality needs additional resea

133 CcCas9 can potentially broaden the existing scope of biotechnological applications of Cas9 nucleases

134 Herein, we report the expanded scope of calcium diazeniumdiolates from benzylic amines,

135 ver ultra-large optical asymmetry on a wider scope of chiral materials.

136 he purpose of this study was to describe the scope of clinical phenotype in female carriers with muta

137 and topologies, and broadens the family and scope of COFs.

138 ystematically measuring usability as well as scope of content.

139 Overall, this reaction broadens the scope of Cr-mediated carbonyl alkylations and discloses

140 cal allylic alkylation expands the synthetic scope of cross-coupling reactions and can be further ext

141 ight/electron microscopy, thus expanding the scope of cryogenic cellular imaging.

142 A broad scope of cycloaddition donors and acceptors participated

143 e probes can be limited by high cost, narrow scope of detection, lengthy protocols and/or cross-conta

144 of ongoing global change across the daunting scope of diversity in Earth's biota and environments.

145 Fickian ion diffusion), which are beyond the scope of each individual tool.

146 pproach that has the potential to expand the scope of electrosynthesis immensely.

147 lity using the graphene grids and expand the scope of EM imaging.

148 lic and allylic C-H bonds, affording a broad scope of enantioenriched primary amines.

149 Given the global scope of ESMs, a comprehensive evaluation of such models

150 Finally, the scope of Gel-BSA-OHG substrate-based ELISA for clinical

151 blished genetic disorders and determined the scope of GUM as a discovery tool in patients with no dia

152 variants that retain the substrate-targeting scope of high-activity CBEs while maintaining minimal Ca

153 some common terminology, review the immense scope of HMMs for applied ecological research and provid

154 The scope of human learning and development poses a radical

155 ormative standard to reassess the limits and scope of human rationality.

156 s modality requires critical analysis of the scope of indications and rules of conduct for trauma tea

157 This minireview attempts to cover the scope of infectious agents potentially implicated in CSA

158 n diet study by expanding its spatiotemporal scope of inference and recommend this integrative method

159 ystem established in Vietnam to identify the scope of influenza viruses present in live bird markets

160 well-documented in North Carolina, the full scope of invasive drug-related infections (IDRIs) has no

161 ols that are expected to further enhance the scope of knowledge attainable through nanometer-scale re

162 imental data on Gal-3 and -7, and extend the scope of KS binding to Gal-1 and -9N.

163 i(II) for other metal ions could broaden the scope of metalloenzyme target.

164 The extension of the substrate scope of mTG beyond canonical amines thus substantially

165 A wide scope of N-arylimine and quinoline derivatives was demon

166 and high-resolution imaging, can extend the scope of neural crest lineage studies beyond development

167 cemases and epimerases, widely expanding the scope of NPN-dependent enzymes.

168 ported additional clinical duties within the scope of ophthalmology, and 3.2% reported being re-deplo

169 res beyond layers and columns may expand the scope of PBI-based materials.

170 vities of a critical care pharmacist and the scope of pharmacy services within the ICU.

171 By considering the broader scope of plant-herbivore-natural enemy interactions that

172 materials and may significantly broaden the scope of polymer applications.

173 e positives, and identifying the appropriate scope of population-based screening efforts are all pote

174 perties of MOFs and, therefore, increase the scope of possibilities for colloidal crystal engineering

175 on-wide, observation-based assessment of the scope of potential seawater intrusion exists.

176 racteristics contribute to understanding why scope of practice differences exist.

177 spective document, the authors delineate the scope of practice in cardio-oncology and the proposed tr

178 the management of addiction as part of their scope of practice, and here we seek to give a name and d

179 y for conservation(1,2), given the shrinking scope of protected areas in many regions.

180 This chemistry expands the known scope of pyridazine/pyrazine chemistry and can be applie

181 icting the Irving-Williams series, while the scope of reactivity remains unexplored.

182 This work expands the scope of reticular chemistry to include, for the first t

183 This work expands the scope of ribosome-mediated polymerization, setting the s

184 Despite two decades of study, the full scope of RNAi in mammalian cells has remained obscure.

185 able comonomers, our methodology expands the scope of ROCOP and gives access to diverse materials fea

186 This protocol extends the scope of saturated azacycles to piperidines, azepane, an

187 on profiling using RNA-seq has increased the scope of sequencing experiments to include more complex

188 The targeting scope of Streptococcus pyogenes Cas9 (SpCas9) and its en

189 tereoselectivity (up to >20:1 dr) for a wide scope of substituents.

190 These measures will increase the scope of such analyses, allowing more accurate model est

191 The application scope of such polymers could be extended to fields such

192 to prepare these materials have limited the scope of synthetic control over their physical propertie

193 nced postintervention monitoring, beyond the scope of TAS, to ensure sustained success.

194 y O-glycosides, significantly broadening the scope of the approach.

195 pathway, created by expanding the substrate scope of the carboxylic acid reductase toward noncognate

196 tion of "probable" has been expanded and the scope of the category "possible" has been diminished.

197 ns isomerization of CTD prolines expands the scope of the code in ways that are not well understood.

198 t reaction times, mild conditions, and broad scope of the coupling partners, it enables the synthesis

199 ates, compromising the overall efficiency or scope of the cycloaddition reaction.

200 human genome, which considerably limited the scope of the DNA methylation analysis in those studies.

201 Moreover, the scope of the indole substrate is very broad, extending t

202 We extended the scope of the microdroplet reaction and obtained a series

203 The scope of the NICE approach is demonstrated via this comp

204 ase count by 55% and expanded the geographic scope of the outbreak.

205 To investigate the mechanisms and scope of the problem, we compared the leadership attainm

206 The scope of the process tolerates a range of nucleophiles t

207 The scope of the process was explored through the labeling o

208 r proved to be an efficient way to widen the scope of the proposed experimental approach to foods tha

209 The mechanistic aspects and scope of the reaction are discussed.

210 The scope of the reaction is demonstrated with 35 examples (

211 The substrate scope of the reaction was also explored in detail.

212 pecies are not well understood, limiting the scope of the relationships used in flow management.

213 Outlined here are studies exploring the scope of the sequential photoelectrocyclization, [1,5]-h

214 The reaction conditions and substrate scope of the transformation have been studied demonstrat

215 lls but a detailed understanding of the full scope of their cognition was, until now, not existent.

216 us of signaling networks but also reveal the scope of their regulatory functions.

217 This condition limits the practical scope of these reactions to simple, inexpensive alcohols

218 nd actions need to be taken now to limit the scope of this anticipated problem.

219 Demonstrated here is the substrate scope of this bioconjugation by attaching a variety of t

220 However, to date, the scope of this catalytic methodology has been limited to

221 The scope of this consideration is broad, and it will not be

222 While the scope of this crosstalk is well-recognized, precise mole

223 The scope of this isocyanide insertion reaction is rather br

224 oles generated a chiral center to extend the scope of this method.

225 aries makes it difficult to characterize the scope of this phenomenon without invasive sampling of ox

226 We demonstrate the scope of this platform through the degradation of therap

227 This report further expands the substrate scope of this reaction by varying the substituents on ar

228 We have explored the full scope of this reaction using complex peptide systems and

229 The scope of this review article is to provide an overview o

230 The scope of this review was to systematize the available sc

231 ng field, their contributions are beyond the scope of this review.

232 The scope of this tandem 1,3-dipolar cycloaddition/rDA react

233 r feedstocks has significantly increased the scope of transition-metal-catalyzed cross-couplings, esp

234 nd data preprocessing steps and widening the scope of valid downstream analyses.

235 The wide scopes of MBH adducts and indolizines were investigated,

236 Yet, scopes of practice in some political jurisdictions (e.g.

237 level factors influencing Nurse Practitioner Scopes of Practice.

238 rchitectures, cognitive constraints, and the scope or resource rational analysis (RRA).

239 This method exhibits wide substrate scope (primary and secondary alcohols) functional group

240 ching for Operative Performance Enhancement (SCOPE) program, 46 surgeons within 4 US academic medical

241 We defined the scope, proposed statements and searched electronic datab

242 lick reactions fulfilled key criteria (broad scope, quantitative yield, abundant starting material, m

243 IFN is strikingly increased in magnitude and scope relative to type III IFN.

244 A broad-scoped review of kiwifruit guides further innovative app

245 A scoping review conducted using the Arksey and O'Malley (

246 Scoping review DATA SOURCES: Four electronic databases -

247 This scoping review explored current literature to identify e

248 Authors completed a scoping review following guidelines from the Joanna Brig

249 Our scoping review identified three consent-related strategi

250 Overall, the papers reviewed in this scoping review indicate that healthcare providers are re

251 A scoping review methodology was employed.

252 We conducted a scoping review of articles published between January 200

253 We performed a scoping review of empirical evaluations of dental studie

254 We also did a scoping review of strategies that could improve adolesce

255 We conducted a comprehensive scoping review of the literature to clarify the meanings

256 We conducted a scoping review of the literature to identify domains and

257 This scoping review revealed that the endoluminal and minimal

258 Through a scoping review, we have utilized an empirically derived

259 We undertook a systematic scoping review.

260 After discussion of the scoping reviews and the evidence update, the task force

261 Additional summaries of scoping reviews are presented for the use of a recovery

262 nce reviews include 16 systematic reviews, 5 scoping reviews, and 1 evidence update.

263 cludes evidence from 7 systematic reviews, 3 scoping reviews, and 12 evidence updates.

264 the extant literature of systematic reviews, scoping reviews, and other related reviews regarding the

265 ons of behaviour change techniques and three scoping reviews.

266 ews and Meta-Analyses (PRISMA) extension for Scoping Reviews.

267 Data integration (scoping-reviews, professional-surveys, expert-opinion, a

268 We demonstrate the broad scope, scalability, and robustness of this unconventiona

269 edy this with studies that are increasing in scope, scale, and visibility.

270 We demonstrate the utility of SCOPE-seq2 for fluorescence, morphological, and expressi

271 ion is impressive with regard to the product scope since primary, secondary, and tertiary alkyl amine

272 limited because of its restricted geographic scope, small sample size, and possible recall bias, whic

273 ors (CARs), no comprehensive survey of their scope, targets and design exists.

274 ungi should be identified in a single assay (scope), taxonomy and nomenclature, discriminating coloni

275 ing the challenging group of mono-alcohols-a scope that stands out among previously reported UV, fluo

276 itional bioluminescent probes are limited in scope, though, as they cannot be easily distinguished in

277 Published and unpublished literature was scoped through development of a research question, ident

278 Preliminary expansion of the scope to 3-vinylindoles and to aza-oxyallyl cations is r

279 Broadening our scope to cytochrome c and lysozyme, we showed that altho

280 ate this dynamic often lack the scale and/or scope to faithfully model the dual and co-dependent natu

281 findings suggest that there is considerable scope to improve the transparency of the hiring process.

282 Expansion of the monomer scope to include enantioenriched vinyl ethers enabled th

283 ignificantly extended the reaction substrate scope to include relatively less electron-rich arenes in

284 of mechanistic export flux models that offer scope to incorporate underlying dynamical and biological

285 monly used RV association tests have limited scope to leverage variant functions.

286 This study suggests there is scope to optimise the contribution of primary care, comm

287 The results yield a great scope to promote the development of robust, efficient an

288 Scope, tolerance for these transition-metal-free C-H/C-L

289 We examined the substrate scope using substituted aromatic and aliphatic derivativ

290 characteristics, including a broad substrate scope, using easy-to-handle alcohols as starting materia

291 Within this scope, we categorize human diseases according to how wel

292 A broad scope with all six-carbon-substituted arene motifs, cont

293 lex (3 mol %) and exhibited a broad reaction scope with different alcohols, allowing primary and seco

294 reoselectivities and showed a wide substrate scope with high atom economy.

295 The transformation shows a broad substrate scope with high chemoselectivity for the synthesis of 8-

296 The strategy showed a good substrate scope with respect to boronic acids as well as 2-carbony

297 The reaction is broad in scope with respect to the (hetero)aromatic aldehyde-deri

298 rheology is inherently complex and broad in scope with wide-ranging applications in the biology, che

299 The reaction shows broad substrate scope, with a range of different electrophiles and boron

300 nd even devices derived from trees in a full scope yet.