ライフサイエンスコーパス: second phase

1 ht at home (n = 97 in first phase; n = 17 in second phase).

2 gdom (UK) and The Netherlands were analyzed (second phase).

3 pe via a DNA end) were not influenced by the second phase.

4 : 23-58) was followed by a slower or plateau second phase.

5 integrity in two phases and apoptosis in the second phase.

6 in two phases, and apoptosis occurred in the second phase.

7 ly has high fatigue resistance but without a second phase.

8 t are large compared with the spacing of the second phase.

9 ranscriptional phase and increase during the second phase.

10 potential to contribute significantly to the second phase.

11 and then exhibited a distinct flat or slower second phase.

12 they interact with the continuously flowing second phase.

13 st phase and 65 patients in 3 centers in the second phase.

14 ceased on the cocaine-paired side during the second phase.

15 demonstrate the role of myosin efflux in the second phase.

16 statistically significant differences in the second phase.

17 ng materials, whereas the sulfides contained second phases.

18 hrough embedding endotaxially nanostructured second phases.

19 In the second phase, 149 patients underwent education/follow-up

20 In the second phase (20-45 min), p300 is recruited to ERalpha b

21 The second phase (2012 onwards) prioritised reforming its he

22 Initial results from the second phase 3 trial (intravenous to oral therapy design

23 After the second phase, 54% (95% CI 35-72) tolerated 1400 mg chall

24 In the second phase, 59 scientists, 21 patients, and 31 stakeho

25 In the second phase, 79 slides from patients with BE (23 sample

26 ism with bright light, the above PRCs with a second phase advance region (afternoon) could support bo

27 In the second phase, all stool samples were tested by GDH and X

28 nt, the more homogeneous distribution of the second phase along the boundaries, and the more uniform

29 The second phase also is associated with a spatial transitio

30 a-TNFR1 feedforward signaling, promoting the second phase and driving RIP1 phosphorylation.

31 ed minimum internal electronic short-circuit second phase and external electronic short-circuit decor

32 erved in BiFeO3 based thin films, iron oxide second phases are often detected.

33 h is most effective when spacing between the second phase assumes the critical crack length of the me

34 ic fields (60T) by increasing the density of second phase BaZrO3 nanoparticles.

35 In the second phase, bedside clinicians were additionally assis

36 A second phase begins around week 2.5 to 3, in which relat

37 In the second phase, beta-sheet forms in the polyQ.

38 fficacy criteria for further analysis in the second phase by reducing renal endpoints 15 to 27% compa

39 In the second phase, Cdk5 activates c-Jun via ROS-mediated acti

40 In the second phase, chains are elongated in a multidirectional

41 f bone marrow-derived macrophages preceded a second phase, characterized by accelerated progression o

42 The second phase, characterized by stable DC-T cell contacts

43 In the second phase, children learn the meanings of larger numb

44 ncentrations, they form recombination-active second-phase clusters.

45 In the second phase content analysis of 33 audio-recorded prima

46 methods to successfully engineer porosities, second phase, crystallography shear-planes and oxygen va

47 In the second phase, de novo synthesis generates ceramide that

48 We show that the rate of second phase decay is determined by the death rate of in

49 a: -0.29; liver, -0.009; P < 0.001), whereas second-phase decline (posttreatment days 4-15) did not d

50 ath/loss of productively infected cells, the second-phase decline in viral RNA with a dose of 250 U/m

51 o modeling prediction that the more profound second-phase decline observed in IFN-alpha-treated patie

52 model, the C/C genotype predicted a steeper second-phase decline when adjusted for race (P = .01).

53 ents who received ribavirin had a more rapid second-phase decrease, compared with patients who did no

54 The second phase demonstrates how real measurements could be

55 the volume fraction, morphology, and size of second-phase dendrites to confine any initial deformatio

56 endent on chlamydospore-inducing cues, and a second phase dependent on Rme1 function and independent

57 damage in causing cell death, whereas in the second phase, depletion of MDMX inhibited cell death.

58 In the second phase, different participants were sequentially a

59 e formation of neuroprogenitors) and not the second phase (differentiation into neurons).

60 itial phase at a constant rate followed by a second phase during which the constriction rate decrease

61 ed from four hPSC lines exhibited first- and second-phase dynamic glucose-stimulated insulin secretio

62 vels decreased approximately 15%, and in the second phase ending at T(release), remaining CaDPA was r

63 shes the molecular circuitry that during the second phase ensures a compatible interaction with the p

64 In the second phase ("equal-reward"), a low monetary reward was

65 In the second phase, ERK1/2 is activated by tPA independently o

66 ocytosis was reduced to basal (P < 0.05) and second-phase exocytosis abolished (P < 0.05) by syn1a kn

67 creased, accompanied with the formation of a second phase, FeNi3, which is softer with a lower work f

68 la enterica serotype Typhimurium but lacking second-phase flagellar antigens, has increased considera

69 s to PI3K or Akt attenuated Formalin-induced second-phase flinching behavior, as well as carrageenan-

70 In the second phase, fMRI of response inhibition showed the exp

71 phase is intrinsically labile and requires a second phase for stabilization in embryos.

72 mechanical coupling in solution, providing a second phase for their study and demonstrating the feasi

73 -1A-betaKO islets showed impaired first- and second-phase glucose-stimulated insulin secretion (GSIS)

74 te an essential positive role for Munc18c in second-phase GSIS and suggest novel roles for Munc18c in

75 of Syt-7 in human islets reduced first- and second-phase GSIS attributed to the reduction of exocyto

76 n, increased islet Ca2+ influx, and enhanced second-phase GSIS.

77 dock) newcomer SGs accounted for the reduced second-phase GSIS.

78 ment of releasable pools required to sustain second-phase GSIS.

79 ximately 60% less insulin selectively during second-phase GSIS; RNAi-mediated Munc18c depletion funct

80 In a slow second phase, GtfB recognizes residues that are already

81 The second phase, host entry by the penetration peg originat

82 A second phase III Food and Drug Administration trial is o

83 ndent and swelling intensity correlates with second phase impedance decrease implicating a causative

84 None of the patients with flat second phase in HDV achieved CVR.

85 The observation that a flat second phase in HDV and HBsAg kinetics was associated wi

86 Effectiveness of a second phase in metallic glass heterostructures to impro

87 rms approximately 900-fold less rapidly as a second phase in the reaction under turnover conditions a

88 ase of endosperm proliferation followed by a second phase in which the embryo grows at the expense of

89 m to form a large seed cavity, followed by a second phase in which the embryo grows to replace the en

90 into the band alignment between PbS and the second phases in these materials.

91 This is a pre-requisite for the second phase, in which the Par complex localises to the

92 etection, localization and quantification of second phase inclusions in thin Aurivillius type films.

93 ads to striking increases in both first- and second-phase insulin release, greatly improved glucose t

94 hesion plaques, multimolecular platforms for second-phase insulin release.

95 oxidation (indirect calorimetry), first- and second-phase insulin secretion (2-h hyperglycemic clamp)

96 quantify the role of incretins in first- and second-phase insulin secretion (ISR) in type 2 diabetes

97 f improvements in indexes of both first- and second-phase insulin secretion (P < 0.02), but with no c

98 l TALK-1 channels as important modulators of second-phase insulin secretion and suggest a clinically

99 secretion (0-10 min) increased by 70%, while second-phase insulin secretion during the first (10-80 m

100 incubation with glucose and the reduction in second-phase insulin secretion induced by blocking R-typ

101 The model indicates that increased second-phase insulin secretion induced by the amplifying

102 Glucose sensitivity of first- and second-phase insulin secretion showed a significant cond

103 Second-phase insulin secretion sustains insulin release

104 kedly decreased in both IFG and IGT, whereas second-phase insulin secretion was decreased only in IGT

105 rglycemic clamp (+125 mg/dL), and first- and second-phase insulin secretion were quantitated.

106 se islets revealed a significant increase in second-phase insulin secretion with a trend toward incre

107 proximal glucose-specific trigger to elicit second-phase insulin secretion, signals downstream to ac

108 n secretion (FPIR), insulin sensitivity, and second-phase insulin secretion.

109 The second phase involved the development of a Markov model

110 The second phase involves following the pathway of emergent

111 2+) from endoplasmic reticulum stores, and a second phase involving STIM 1 (stromal interaction molec

112 on the outcome of any defense response, the second phase is a period of syncytium maintenance (susce

113 reduced by up to approximately 29% when the second phase is added.

114 lds in a biphasic process, in which only the second phase is affected by the known mutations.

115 The second phase is dedicated to the assembly of [4Fe-4S] pr

116 The second phase is dependent on the activation of the chlor

117 A second phase is exponential, seen in early-onset cancers

118 The second phase is formed by gel-like assemblies of the dis

119 is initially flooded with one phase before a second phase is injected via a flow-rate-controlled pump

120 o a prehairpin intermediate (PHI), while the second phase is marked by transition from the PHI to the

121 viruses that replicate in human cells; this second phase is modulated by breastfeeding.

122 Strengthening by precipitation of second phase is the guiding principle for the developmen

123 The second phase is the loss of CR and reduction to the dife

124 utrition perfusion augmented both first- and second-phase ISR but first-phase ISR more in T2DM subjec

125 endin(9-39) significantly reduced first- and second-phase ISR in both HS and T2DM subjects.

126 sulted in a significantly greater first- and second-phase ISR in HS compared with T2DM subjects.

127 In the second phase, it combines these small seeds to build lar

128 IP10-induction correlated with first- and second-phase kinetics and with ribavirin serum concentra

129 loss of trimeric structure occurring in the second phase, leaving the flexible extracellular loops a

130 which can easily be confounded by unobserved second phase magnetic inclusions.

131 els recovered to baseline, was followed by a second phase marked by an opposing down-regulation of en

132 In a second phase, microtubules and the dynein motor, in conn

133 equatorial ring formation), but also for the second phase (migration towards the animal pole).

134 econd phase's size, and beyond, the specific second phase morphology of the heterostructure is crucia

135 bands between the host PbS and the embedded second phases, MS (M = Cd, Zn, Ca, and Sr).

136 In the second phase, nine articles were excluded from the analy

137 In a second phase, no differentiation occurs while extensive

138 The second phase occurred once the membrane area from preexi

139 experienced biphasic inflammation, with the second phase occurring after the resolution of cytokine

140 At large positive pressure, a second phase of 2D monolayer ice, i.e. the puckered squa

141 This is the second phase of a 10-year follow-up study of a cohort of

142 This paper reports the findings of the second phase of a study; the first has been reported els

143 learance phase, and then the mice received a second phase of Ag and tocopherol treatments.

144 n and lung lavage fluid were reversible in a second phase of Ag challenge without tocopherols.

145 Cyr61 siRNA inhibited a second phase of Akt phosphorylation measured 12 hours af

146 ng high-throughput sequencing have enabled a second phase of association studies that assess the cont

147 During the second phase of autophagy, the size of autophagosomes an

148 of the regulatory mechanism controlling the second phase of biphasic WNT activity essential for embr

149 e Hh-dependent module is not limited to this second phase of bone growth: during later larval develop

150 role in open state maintenance and reveals a second phase of CAD/STIM1 binding after channel opening.

151 In contrast, a second phase of calcium influx occurring minutes before

152 quenching of dAP fluorescence followed by a second phase of dAP quenching, which has nearly the same

153 Disruption of the second phase of Delta expression specifically abolishes

154 activated by Delta signaling even during the second phase of delta expression, when this gene is tran

155 of A13 development but are required for the second phase of development and for maintenance of this

156 This second phase of development is dependent on NF-kappaB si

157 econstructions, we further characterized the second phase of development of the A13 nucleus in the mo

158 The second phase of discovery focused on the de novo design

159 In the second phase of dissemination, the nonmotile spirochetes

160 ymph gland, the tissue that orchestrates the second phase of Drosophila hematopoiesis.

161 The second phase of ductal growth and branching is driven by

162 esponse to EGFR activation, which leads to a second phase of EGFR-P and subsequent exaggerated mucin

163 t affect the first phase but ameliorated the second phase of endothelial barrier disruption and apopt

164 In contrast, the second phase of ERK->MSK1 activation drove apoptosis and

165 In the second phase of expression quantitative trait loci analy

166 tment with l-THP significantly inhibited the second phase of formalin-induced pain behavior.

167 rathecal injection and completely blocks the second phase of formalin-induced spontaneous nocifensive

168 intolerance and substantial reduction of the second phase of glucose-stimulated insulin secretion (GS

169 Given that Syntaxin 4 functions in the second phase of glucose-stimulated insulin secretion (GS

170 lta-deficient islets revealed an accelerated second phase of glucose-stimulated insulin secretion.

171 r CD8(+) T cell expansion and the associated second phase of GVHD.

172 and a premature entry into anagen during the second phase of hair cycling without a detectable change

173 HBsAg kinetics of decline paralleled the second phase of HDV decline consistent with HBsAg-produc

174 parasitemia and severe anemia, followed by a second phase of hyperparasitemia, more profound anemia,

175 omponent lipoteichoic acid (LTA) governs the second phase of immune responses when high concentration

176 n-12-dependent, Interferon-gamma-independent second phase of inducing the transcription factor T-bet.

177 In 2005 imatinib was added to the second phase of induction (N = 89, early imatinib).

178 The second phase of inflammation could be avoided by using G

179 om isolated islets selectively amplified the second phase of insulin release, consistent with the rol

180 elicit strong host responses, followed by a second phase of intense gene expression.

181 The second phase of JNK phosphorylation was dependent on aut

182 The second phase of JNK phosphorylation-Bcl-2 phosphorylatio

183 c, but also begins exactly at the onset of a second phase of morphogenesis, when the early bone begin

184 ic neuroblasts (NBs) in Drosophila undergo a second phase of neurogenesis to generate adult-specific

185 Data from the second phase of OHTS also were examined, and control eye

186 s found for eyes that began treatment in the second phase of OHTS, but no significant change in MD or

187 on revealed poor mice exposure; therefore, a second phase of optimization was required.

188 A second phase of persistent MT growth requires the cytoso

189 lasia, which developed postnatally, when the second phase of pituitary expansion occurs.

190 The second phase of PKD activation was followed by prolonged

191 The role of Mer kinase in regulating the second phase of platelet activation generates an opportu

192 Within the second phase of polymer growth, opened hGBP1 molecules c

193 cal spreading depression wave, we observed a second phase of prolonged, negative direct current shift

194 ring the first 6 to 7 minutes, followed by a second phase of response decay or of no further incremen

195 d quantitative measurement revealed that the second phase of RhoA activation is insensitive to rapid

196 We showed that the first and second phase of RhoA activity are dependent on p63 and C

197 consistent with its selective effect on the second phase of secretion.

198 activation of SMADs, TGF-beta also induces a second phase of STAT phosphorylation that requires SMADs

199 The second phase of study was a method development to realiz

200 maturation throughout childhood, a critical second phase of synaptic overproduction and elimination

201 The second phase of the biphasic force decay upon release of

202 In particular, in the second phase of the catalytic cycle, which involves thre

203 During the second phase of the disease, after the onset of neurolog

204 vement is very rarely seen and occurs in the second phase of the disease.

205 od or cerebrospinal fluid that appear in the second phase of the disease.

206 morph line) served as a reference when, in a second phase of the experiment, either prototype was bri

207 the duration of nocifensive behavior in the second phase of the formalin assay.

208 S inhibitor NOArg lowered both the first and second phase of the formalin response.

209 As part of the second phase of the International Cancer Benchmarking Pa

210 Participants in the second phase of the Marine Resiliency Study (MRS-II) inc

211 As part of the second phase of the North American Prodrome Longitudinal

212 596 clinical high-risk participants from the second phase of the North American Prodrome Longitudinal

213 ected from January 2009 to April 2013 in the second phase of the North American Prodrome Longitudinal

214 Hence, during this second phase of the pandemic, extensive viral migration

215 The aim of the second phase of the PARTNER study (PARTNER2) was to prov

216 in a genome-wide association study from the second phase of the Psychiatric Genomics Consortium, and

217 137 publications were scrutinized during the second phase of the review.

218 /polysulfurated forms of SufE accounts for a second phase of the slow catalytic turnover rate.

219 The second phase of the study asks: can a mathematical feedb

220 In the second phase of the study, the frequency of these abnorm

221 In a second phase of the study, we use one family-based data

222 tion and process-focused outcomes during the second phase of the study.

223 rticipants was requested to take part in the second phase of the study.

224 s required for recovery of IIS activity in a second phase of the systemic response to DNA damage.

225 dent roles in promoting the progression of a second phase of the viral lytic cycle and that these rol

226 erlies shifted northward, producing a warmer second phase of the YDS in Europe.

227 In a second phase of their migration, the surviving AMG stere

228 r option on POG 9407 after completion of the second phase of therapy.

229 The patient is currently in the second phase of treatment without gastrointestinal and j

230 gnificantly later in development, during the second phase of turtle trunk neural crest emigration.

231 While the extremely slow or flat second phase of viral RNA inhibition observed in vitro,

232 ifferent mechanisms underlying the first and second phases of neurovascular dysfunction.

233 models, fail to capture the progressive, or second, phase of PAH.

234 gated in detail the effect of CdS and ZnS as second phases on the thermoelectric properties of p-type

235 Furthermore, formalin-induced second-phase pain was suppressed by spinal injection of

236 grain growth in a Ti6Al4V alloy system with second phase particle inclusions representative of oxide

237 soriented grains, and the suppression of big second phase particles in this 3.2 mum thick REBa2Cu3Ox

238 The presence of second phase particles, which act as pinning sites for b

239 clines in the first phase, antibodies in the second phase persisted at SBA titres greater than 128.

240 In the second phase, predominantly lambda-chain-positive B cell

241 The second phase promotes prolonged, higher level MCP-1 secr

242 slets enhances the first-phase elevation and second-phase pulses of insulin.

243 imed, release-ready granule pools, while the second phase relies on granule mobilization from the res

244 curs in response to StxB1 subunit, while the second phase requires StxA1 subunit activity.

245 The second phase requires the activity of a pool of myosin t

246 The second phase, responsible for leukocyte exit from the gl

247 orylation and activation of Src, whereas the second phase resulted from the sequestration of activate

248 en removal rate continued to decrease in the second phase, resulting in an overall removal rate of 80

249 In the first and second phases, rising metabolite levels and increased po

250 This spacing should coincide with the second phase's size, and beyond, the specific second pha

251 During the second phase (sampled at E38-E45), the loosely banded S-

252 Second-phase secretion was similar across all NGT and IG

253 In the second phase, SHB1 enhances embryo cell proliferation an

254 through a one-shot measurement within a few seconds, phase-shifting interferometry (PSI) successfull

255 However, the second phase slope of viral decline was improved with SA

256 sing a biphasic model to describe first- and second-phase slopes of viral decay during therapy.

257 In the second phase specific T cells invade the infected organ,

258 In the second phase, Src family kinases phosphorylate tyrosyl r

259 tants had a shorter first phase and a longer second phase than the wild-type protein, one mutant had

260 synthesis-independent manner, followed by a second phase that is more delayed and dependent on prote

261 rst phases and a 3.5-millisecond rectilinear second phase that was half the voltage of the first phas

262 In the second phase (the oxidase phase), oxidation of alkenes a

263 In the second phase, the critically short telomeres lead to gen

264 In the second phase, the NC domain binds RNA, and the bound for

265 During the second phase, the WAVE (WASP-family verprolin homologous

266 In the second phase, these effector cells seek out and eliminat

267 In the second phase, they answered with respect to two predefin

268 In the second phase, they were divided into four treatment grou

269 sic waveform had a 60% first-phase and a 50% second-phase tilt.

270 microstructures can arrest shear bands at a second phase to prevent cracks from exceeding critical s

271 ng the microstructural length scales (of the second phase) to mechanical crack-length scales.

272 ric light (n = 243 in first phase; n = 25 in second phase) to those with electric light at home (n =

273 Sofosbuvir + ribavirin are cost-effective as second-phase treatments following peginterferon + ribavi

274 In the second phase, type II genes (hCGbeta1 and -2) were forme

275 amellar scaffolds are often infiltrated by a second phase, typically a soft polymer matrix, a hard ce

276 a favorable genotype had greater first- and second-phase viral kinetics (P = 0.004 and P = 0.036, re

277 tained virological response as the first- or second-phase viral kinetics responses.

278 First- and second-phase viral kinetics were evaluated.

279 gamma-producing NK cells was greater in fast second-phase virological responders than in slow respond

280 in vitro stimulation by IFN-alpha during the second-phase virological response.

281 In the second phase, viruses with linked MDR mutations rapidly

282 The slowly upward shift in the second phase was consistent with the slowly increasing t

283 t progressively lost as the amplitude of the second phase was incrementally increased above that of t

284 first was mainly ozone controlled, while the second phase was more related to HO(*) reactions.

285 When the amplitude of the second phase was twice that of the first phase, there wa

286 hanism for the Rac2-led PLD2 inhibition (the second phase), we used leukocytes from wild-type (WT) an

287 In a second phase, we applied an unbiased machine learning pr

288 For the second phase, we assessed the effect on mortality in tri

289 In the second phase, we carry out the alignment in the compress

290 lthough much remains to be learned about the second phase, we feel that an understanding of the first

291 In the second phase, we included all 218 subjects with mild cog

292 In this second phase, we release a new server-side specification

293 o increased synaptic strength, we identify a second phase where this potentiation is profoundly reduc

294 Linoleic acid in pastures was highest in the second phase which coincided with mid-lactation days (p<

295 healthcare centers Lagos State, Nigeria and second phase which consists of definitive clinical evalu

296 complex, NFATc1.STAT-3, to its promoter, the second phase, which is more robust, depends on NFATc1-me

297 Critical design aspect is a soft second phase, which is most effective when spacing betwe

298 tantly, the transition from the first to the second phase, which is the main determinant of the final

299 ex enhances the activity associated with the second phase, while modestly inhibiting the activity ass

300 ontrol participants underwent OIT during the second phase, with subsequent DBPCFC.