ライフサイエンスコーパス: secondary

1 ugh the use of mixed crystals containing the secondary 1,4-phenylene pillar.

2 Conversely, the secondary (2 degrees Mn) type facilitates and has low an

3 c rather than in LC3 lipidation brings this "secondary" activity of ATG16L1 in full light and emphasi

4 f an adverse-risk karyotype, the presence of secondary acute myeloid leukaemia arising from previous

5 Secondary acute myeloid leukemias (AMLs) evolving from a

6 iable risks may be effective for primary and secondary AF prevention.

7 A secondary aim was to assess relationships between nausea

8 The secondary aim was to gauge the confidence and experience

9 Our secondary aim was to model volume by using restricted cu

10 Our secondary aims were to determine the trends of LT, reaso

11 Mechanistically, the dehydrogenation of secondary alcohol follows clean pseudo-first-order kinet

12 is developed from easily available benzylic secondary alcohols employing thiophenol-stabilized iodon

13 Various secondary alcohols including cyclic and acyclic alcohols

14 ith different alcohols, allowing primary and secondary alcohols to be employed as nonhazardous and gr

15 -disubstituted ketones via the alkylation of secondary alcohols with primary alcohols is reported.

16 ded to five-membered and six-membered cyclic secondary alcohols.

17 riven photochemical oxidation of primary and secondary aliphatic alcohols using a pair of flavin and

18 A broad range of primary and secondary amines may be inserted by this method, includi

19 g of 1,3-dihydro-1H-benzimidazol-2-ones with secondary amines.

20 rimary amines, as well as cyclic and acyclic secondary amines.

21 Secondary analyses considered natural versus surgical pr

22 Secondary analyses indicated that this interaction was m

23 These are secondary analyses of a randomized controlled trial in r

24 Secondary analyses were conducted among those with HIV-i

25 In secondary analyses, normalized pT(308) AKT1 was positive

26 In secondary analyses, saliva Mn, hair Cu, and saliva Cr we

27 In secondary analyses, we also assessed the ability of NM-M

28 This secondary analysis examined factors related to initiatin

29 Secondary analysis included myocardial infarction (MI) a

30 This study was based on a secondary analysis of cross-sectional data collected as

31 rtality relationship.Methods: We undertook a secondary analysis of patients with ARDS, who were invas

32 A secondary analysis of recovered missing vital status dat

33 NCT03194932) and is now enrolling to address secondary and exploratory objectives.

34 wide range of epoxides and oxetanes yielding secondary and tertiary alcohols in excellent yields and

35 rder-to-order shift, adopting higher average secondary and tertiary structure.

36 ns between the stage of syphilis (primary vs secondary) and behavioral data collected by computer-ass

37 e of aliphatic fluorides, including primary, secondary, and tertiary benzylic fluorides as well as un

38 2852 women (and their 3070 fetuses) from 29 secondary- and tertiary-level hospitals across Banglades

39 sphosphate (PIP(2)) activates the channel; a secondary anionic lipid site has been identified, which

40 PCE, where tau protein was sandwiched with a secondary antibody labeled with horseradish peroxidase (

41 ive immunoassay format without the need of a secondary antibody, or washing steps.

42 nt in primary auditory cortex and refined in secondary auditory cortex, in which sound repetition fac

43 sporadic axon damage followed by progressive secondary axon damage.

44 Patients with lean NAFLD had higher serum secondary BA and FGF19 levels and reduced 7-alpha-hydrox

45 ITC quantifies primary and secondary binding separately, whereas microscale thermop

46 a series of reactions leading to primary and secondary brain injuries and permanent neurological defi

47 ter enlargement of shoot modules and quicker secondary branching of roots.

48 m an unusual 12-connected pai-stacked pyrene secondary building unit (SBU) and a typical 12-connected

49 structure with fcu topology built on a Th(6) secondary building unit and a tetrazole-based linker.

50 ecular building block (MBB) as a tetrahedral secondary building unit, a prerequisite for zeolite-like

51 sitions for the generation of heterometallic secondary building units (SBUs) with variable nuclearity

52 efined single site catalyst on MOF inorganic secondary building units, in particular the in situ synt

53 was associated with the later development of secondary Candida infection.

54 a possible neurovascular contact and exclude secondary causes.

55 ion, biosynthesis, and, in specific tissues, secondary cell wall (SCW) deposition, yet the coordinati

56 network of lignin biosynthesis genes during secondary cell wall formation in P. deltoides.

57 tal transition from rapid cell elongation to secondary cell wall synthesis.

58 and localizes around forming pits and under secondary cell wall thickenings in metaxylem cells.

59 plex phenolic biopolymer found mainly in the secondary cell walls of vascular plants, where it contri

60 We also show that sorghum secondary cell walls present a high ratio of amorphous t

61 Secondary cell walls provide a physical barrier that pro

62 l UK nests derived from the European zone of secondary colonisation, rather than from the native rang

63 A secondary composite 1 event occurred in 76 patients (23.

64 69 [95% CI, 0.59-0.80]; P=0.000001); the key secondary composite end point occurred in 16.6% versus 1

65 ents may directly influence the selection of secondary concomitant alterations to promote oncogenic s

66 have facilitated a dynamic of isolation and secondary contact.

67 e neocortex are well studied, what generates secondary cortical areas is virtually unknown.

68 patients with RA receive poorer primary and secondary CVD preventive care than other high-risk patie

69 This manuscript presents results from a secondary data analysis for 1,022 women aged 15-24 who r

70 A secondary data analysis was performed with data collecte

71 f photoreceptors and a role for apoptosis in secondary degeneration of cones, highlighting the import

72 e effects on retinal neurons via influencing secondary degeneration process.

73 Potato tuber formation is a secondary developmental programme by which cells in the

74 t regulations and patient deferrals, and the secondary economic impacts of the pandemic.

75 Secondary effectiveness outcomes included mean monocular

76 uced by bedaquiline and moxifloxacin through secondary effects downstream from their main target path

77 Improving our understanding of these secondary effects is becoming vital now that FUS-BBB ope

78 Here we report the key secondary efficacy endpoint of the proportion of partici

79 Secondary end points included angiographic and safety ou

80 Secondary end points included overall survival and safet

81 Secondary end points included predisposing factors for t

82 Secondary end points included progression-free survival

83 Secondary end points were 5-year locoregional control an

84 Primary and secondary end points were assessed in a hierarchic model

85 Secondary end points were locoregional control, local co

86 ignificant benefit with respect to all other secondary end points, including the time to first sympto

87 Of the 6 prespecified secondary end points, none showed a statistically signif

88 was assessed in the first 11 months, and the secondary endpoints (efficacy by baseline serostatus, se

89 The secondary endpoints analysed within this report include

90 Secondary endpoints did not reveal any significant group

91 Secondary endpoints included 6-item asthma control quest

92 rence at 3-year follow-up, respectively, and secondary endpoints included anastomotic leakage rate.

93 Secondary endpoints included fatigue, sexual function, a

94 The secondary endpoints included virological suppression at

95 Secondary endpoints were antimicrobial consumption, in-h

96 Secondary endpoints were duration of response, disease c

97 Key secondary endpoints were overall survival, event-free su

98 Secondary endpoints were survival and inflation-adjusted

99 Secondary endpoints were the effects of S44819 on the NI

100 Secondary endpoints were the ICU length of stay and the

101 Secondary endpoints were treatment failure (biopsy-prove

102 Secondary endpoints were: hemispheric space-modifying ed

103 y and anaphylaxis episodes were evaluated as secondary endpoints.

104 sive building heating, but it can also drive secondary energy-conversion steps.

105 ive success with pair-bond length could be a secondary factor favouring perennial social monogamy, pa

106 .9%) had primary glaucoma and 74 (87.1%) had secondary glaucoma.

107 tcome measure was the presence or absence of secondary glaucoma.

108 uity, endothelial cell count (ECC), rates of secondary graft failure (SGF), and postoperative complic

109 Young (<29 y) secondary grasslands were composed of weedy species, and

110 ichness increased over decades to centuries, secondary grasslands were still missing characteristic o

111 The secondary group consisted of patients with a history of

112 f bee communities between primary and mature secondary (>100 years old) fire-maintained forests in Ge

113 cal response when she was 18 years old), and secondary haemochromatosis.

114 actice Research Datalink (CPRD), linked with secondary healthcare and mortality data, to derive an op

115 Others suffer from secondary HLH as a complication of infection, malignancy

116 enhanced virulence following emergence into secondary hosts with immune systems that diverge from th

117 ain is anchored to the helical scaffold by a secondary hydrophobic core, pinning down the long loops

118 data, calibration rulers, or comparisons to secondary imaging modalities.

119 were aged at least 18 years, with primary or secondary immune thrombocytopenia and platelet counts le

120 Prevalence of hypertension (both primary and secondary) in children and adolescents in the US ranges

121 We found substantial evidence of secondary infections among household contacts.

122 9.1%) in the standard care group experienced secondary infections, 47 (31.1%) vs 42 (28.3%) needed in

123 licit trained immunity and protection from a secondary infectious challenge in the skin.

124 cause of infertility in men with primary and secondary infertility, respectively.

125 states and might underestimate the impact of secondary interactions.

126 n-based surveillance data, we quantified the secondary invasive group A Streptococcus disease risk am

127 Time-of-flight secondary ion mass spectrometry (TOF-SIMS) detectors hav

128 ctrometry (IMS) combined with time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging.

129 reports on the first systematic study using secondary ion mass spectrometry with MeV ions (MeV-SIMS)

130 In general, the secondary ion signals were significantly enhanced by up

131 The differences as observed by secondary-ion mass spectrometry, differential scanning c

132 atment completion combined with 12 months of secondary IPT would avert 2472 DALYs (95% UI -888 to 780

133 Based on primary and beta-secondary isotope effects, it is established that the is

134 sed for pulmonary nodules (PN) detection and secondary lung cancer (SLC) diagnosis.

135 lymphovenous bypass (LVB), on patients with secondary lymphedema of the upper or lower extremity (UE

136 tiotemporal scenarios of antigen access into secondary lymphoid organs, antigen valency and cellular

137 a(+), double-negative (DN) T cells, in mouse secondary lymphoid organs.

138 ents with histologically verified primary or secondary lymphoma of the lacrimal gland were included.

139 med of patients undergoing adrenalectomy for secondary malignancy (2002-2015) at 6 institutions.

140 The significant amount of secondary materials stocked in products, buildings, and

141 nd 2% to 6% of PNH patients go on to develop secondary MDS/AML by 10 years of follow-up.

142 phering molecular mechanism of regulation of secondary metabolism and gene expression in the glandula

143 Microbial secondary metabolism is a reservoir of bioactive compoun

144 own for their role in organisms' primary and secondary metabolism.

145 We apply PRISM 4 to chart secondary metabolite biosynthesis in a collection of ove

146 hic acid A as the founding member of a novel secondary metabolite family.

147 rcurrent chromatography (HPCCC) to study the secondary metabolite formation, whereby HPCCC showed a s

148 ndant CAZymes (598 per species) and prolific secondary metabolite gene clusters (73 per species) in s

149 EOs are complex mixture of secondary metabolites (terpenes, phenolic compounds, alc

150 ulfate, cysteine, and some sulfur-containing secondary metabolites accumulated in higher amounts in A

151 important for biosynthesis of plant defense secondary metabolites and repressed the accumulation of

152 es such as avermectin are mainly produced as secondary metabolites during the stationary phase of gro

153 for the first time in addition to well-known secondary metabolites including emodin, aloe-emodin, bet

154 es, phenotypic assays, and identification of secondary metabolites, highlights the genetic and metabo

155 y have favored this functional diversity for secondary metabolites, including signaling robustness an

156 d the main bioactivities described for these secondary metabolites, to offer an overview of the situa

157 CrO(4)(2-), calcite and gypsum are formed as secondary mineral phases, which allows for oxyanion part

158 tly administered to patients with primary or secondary mitochondrial dysfunction, might be due to its

159 (HF) patients with moderate-severe or severe secondary mitral regurgitation with transcatheter mitral

160 ) of primary MN cases, 3% (one out of 35) of secondary MN cases, and in 0% of healthy controls.

161 Secondary Mo atoms on the surface act as electron pumps

162 Fourth, because secondary mortality effects and indirect effects of para

163 We find that these 'secondary motifs' bind Rbfox robustly in cells and that

164 - 11 years of age, 68% men) with significant secondary MR were included.

165 th (from septicemia) during remission, and 1 secondary myeloid leukemia.

166 ive apoptosis and promotes immunostimulatory secondary necrosis by binding to the phagocytic marker p

167 anisms: psychosine-induced demyelination and secondary neuroinflammation from galactosylceramide stor

168 ottom of the suboxic zone and coincided with secondary NO(2) (-) maxima and available NH(4) (+) .

169 evolved from viral proteases through gain of secondary nuclease activity.

170 This finding highlights the generality of secondary nucleation and its independence of the detaile

171 irect evidence that self-replication through secondary nucleation occurs along the sides of fibrils,

172 transient species during the aggregation and secondary nucleation of the Abeta42 peptide.

173 lly high degree of catenation stems from the secondary nucleation of the precursor molecules around t

174 atalytic proliferation of amyloid fibrils by secondary nucleation on the fibril surface.

175 both by competing for monomers and blocking secondary nucleation sites.

176 A secondary objective of the trial was to assess angina-re

177 A secondary objective was to assess anthropogenically deri

178 microstent in different types of primary and secondary open angle glaucoma.

179 motional restriction without a well-defined secondary or tertiary hydrogen bond stabilized structure

180 bulk particle phase of a viscous atmospheric secondary organic aerosol (SOA) can have a profound impa

181 Anthropogenic emissions alter secondary organic aerosol (SOA) formation chemistry from

182 omposition and physicochemical properties of secondary organic aerosol (SOA).

183 es in atmospheric aerosols, to contribute to secondary organic aerosol mass.

184 ons for nucleation and growth of atmospheric secondary organic aerosols and atmospheric OH recycling.

185 utcome measure, while change in CDVA was the secondary outcome measure.

186 and contaminants were assessed, along with a secondary outcome of time to positivity (TTP) of blood c

187 ary outcome was all-cause mortality, and the secondary outcome was cause-specific mortality.

188 The secondary outcome was control over the SMA assessed in n

189 Weight change at 18 months was a secondary outcome.

190 Secondary outcomes - clinical symptom scores at 2, 3, an

191 The secondary outcomes analyzed here were OS, TTP, and DFS.

192 Secondary outcomes included additional QoL assessments (

193 Secondary outcomes included agreement to the genotype-gu

194 Secondary outcomes included an IGA score indicating clea

195 Secondary outcomes included corrected distance visual ac

196 Secondary outcomes included individual components of the

197 Secondary outcomes included major adverse cardiovascular

198 Secondary outcomes included neonatal acquisition of any

199 Secondary outcomes included pain and satisfaction scores

200 Secondary outcomes included peri-intubation complication

201 Prespecified secondary outcomes included primary outcome components,

202 The secondary outcomes included the change from baseline in

203 Secondary outcomes included total inpatient opioid use,

204 primary outcome of the study was safety, and secondary outcomes included visual acuity, microperimetr

205 Secondary outcomes including the score on the Owestry Di

206 f alcohol withdrawal symptoms and associated secondary outcomes of alcohol craving and mood, anxiety,

207 Analyses of the secondary outcomes showed that a higher between-day vari

208 Secondary outcomes were cardiovascular disease (CVD) and

209 Secondary outcomes were cumulative probabilities of infe

210 Secondary outcomes were multimodal imaging results.

211 Secondary outcomes were postoperative opioid consumption

212 Secondary outcomes were postoperative pancreatic fistula

213 Secondary outcomes were safety, survival, and functional

214 Secondary outcomes were scores six months post treatment

215 Other secondary outcomes were similar in the two groups.

216 The secondary outcomes were the molecular diagnostic yield,

217 Secondary outcomes were the percentage of cases associat

218 ences were found for any of the prespecified secondary outcomes, including changes in knee pain asses

219 For the secondary outcomes, only the men's UBL intervention sign

220 This pattern generally held for secondary outcomes.

221 maintained over time, were observed for most secondary outcomes.

222 and fidelity) were additionally evaluated as secondary outcomes.

223 this aim, a kinetic study of the primary and secondary oxidative process was run and the kinetic para

224 d sulfur dioxide concentrations (a marker of secondary particle formation).

225 ncludes findings on primary, functional, and secondary patency at 12 months; reinterventions; and add

226 distribution for rhamnogalacturonan lyase, a secondary pectinase hydrolyzing the pectic heteropolymer

227 dinal growth, the cambium-based formation of secondary phloem depends on the function of SUPPRESSOR O

228 els can be therefore envisioned as models of secondary plant cell walls prior to lignification.

229 r care, mobility assessments, and consistent secondary prevention can prove to be key elements to imp

230 S) mean profile (3.9 vs 3.3, p = 0.01), more secondary prevention indication for a defibrillator (64.

231 ly met very high-risk criteria for intensive secondary prevention lipid-lowering therapy (28.3% vs. 4

232 disease, their effectiveness in primary and secondary prevention of complications is still uncertain

233 XI are potentially tractable new targets for secondary prevention of ischaemic stroke, while factor V

234 may identify participants closest to MCI for secondary prevention trials.

235 of sinapic acid, from C4 to C12, reduced the secondary products of oxidation, when echium oil emulsio

236 psing-remitting multiple sclerosis (RRMS) to secondary progressive MS (SPMS) represents a huge clinic

237 edictors (within 5 years of presentation) of secondary progressive MS at 30 years were presence of ba

238 ddition of 1.8g n-3 PUFA to standard of care secondary prophylaxis in elderly patients who have survi

239 s idiopathic intracranial hypertension), and secondary pseudotumor cerebri, in which the cause can be

240 imary radical prostatectomy (RP) (79/187 had secondary radiotherapy), 30 had undergone primary radiot

241 ribute most to the hidden units to develop a secondary random-forest classifier for directly predicti

242 ed cancers [26 of 3156]) were detected after secondary recall through quality assurance sessions.

243 cacy; primary - requiring one treatment, and secondary - requiring two treatments (ii) complication a

244 However, primary or secondary resistance to immunotherapy prevents benefits

245 After secondary review, 91.1% of manual-positive/automation-ne

246 (grade point sum, non-eligibility for upper secondary school and national test results) and measured

247 onest type of refractive error found amongst secondary school students.

248 pared it with the non-obligate ectoparasitic secondary screwworm flies, C. macellaria, that invade ne

249 CD277 was secondary, serving as a mandatory coactivating ligand.

250 s, angiogenesis, metastasis, and invasion to secondary sites.

251 angstrom resolution, sufficient to identify secondary structural elements and produce an atomic mode

252 Protein hydration and secondary structure appeared to be key factors affecting

253 ich are measures of uncertainty in predicted secondary structure at each position in the sequence; th

254 side chain are determined by the type of the secondary structure at the attachment site.

255 alysis indicated that Asp t 36 shows similar secondary structure content and temperature sensitivity

256 g restrictions and suggests that the protein secondary structure defines not only tertiary geometry,

257 ed a suppression of the response of specific secondary structure elements, indicating that the intrac

258 ehavior of food proteins by determination of secondary structure elements.

259 We investigated the role of in vivo RNA secondary structure in miRNA cleavage by developing the

260 BID fibers display both types of secondary structure in the fiber, whereas BAX was conver

261 FTIR studies revealed alterations in protein secondary structure induced by plasma, particularly cont

262 G-quadruplex (G4) is a noncanonical secondary structure of DNA or RNA which can enhance or r

263 ngly associated with the modification of the secondary structure of shrimp proteins, including the in

264 ontacts form before or concurrently with the secondary structure of the disordered protein)-an observ

265 d interrogate the impact of STR sequence and secondary structure on their genomic representation and

266 Finally, DeepMSA was used for secondary structure prediction and resulted in statistic

267 In this model, secondary structure prediction programs are used to calc

268 currently available for both 3- and 8-state secondary structure prediction.

269 r: samples tree graph topologies from an RNA secondary structure to predict corresponding tertiary to

270 ngle nucleotide polymorphisms can affect RNA secondary structure, and here we show that single nucleo

271 hough the N-terminal region of RNF4 bears no secondary structure, it maintains a compact global archi

272 m outside binding motifs through altered RNA secondary structure.

273 -40) was less prone to adopt the alpha-helix secondary structure.

274 nstraints are relieved in the absence of RNA secondary structure.

275 as high proline content, and lacks predicted secondary structure.

276 NA sequencing and machine learning to detect secondary structures in cellular RNAs.

277 we show that replication hurdles, including secondary structures in template, slowed helicase, or un

278 s, the atomic-level contributions of various secondary structures of luciferase to its fold's mechani

279 lar dynamics simulations to examine specific secondary structures that resist mechanical unfolding wh

280 ontrolling the formation of higher-order DNA secondary structures to regulate transcription beyond it

281 DNA and RNA can adopt various secondary structures.

282 o test the functional relevance of viral RNA secondary structures.

283 their sequences upon their G-quadruplex and secondary structures.

284 For more challenging substrates, such as secondary sulfamides, the reaction efficiency is documen

285 ve analysis of MSM diagnosed with primary or secondary syphilis at Melbourne Sexual Health Centre bet

286 ally accurate, as independently validated by secondary testing.

287 xicities from targeted therapies are usually secondary to "on target toxicities." Management is large

288 Participants were 55 to 90 years with GA secondary to age-related macular degeneration (AMD) and

289 of ECC remodeling in the cardiac dysfunction secondary to chronic sympathetic activity.

290 m acute respiratory distress syndrome (ARDS) secondary to influenza A(H1N1) infection and 10 age-matc

291 the majority of preventable SCEs (74%) were secondary to provider management factors.

292 p adverse LV remodeling following I/R injury secondary to the collateral damage from sustained myocar

293 y reduced tumor-initiating cell frequency in secondary transplants and reduced the formation of spont

294 C homing to the endothelium, a first step in secondary tumor formation.

295 view discusses the current literature on the secondary use of electronic health record data for clini

296 , to May 24, 2020, that were recorded in the Secondary Uses Service Admitted Patient Care database.

297 mmunity among measles cases, associated with secondary vaccine failure and modified clinical illness,

298 how a primary vascular insult in addition to secondary vascular damage due to ganglion cell damage.

299 ildren treated with dabigatran etexilate for secondary venous thromboembolism (VTE) prevention.

300 Secondary walls were affected also in the interfascicula