ライフサイエンスコーパス: secretion pathway

1 may represent a novel stress-induced protein secretion pathway.

2 is a vital component of the general protein secretion pathway.

3 ry autophagy, an autophagy-based alternative secretion pathway.

4 fector proteins to plant cells via a type IV secretion pathway.

5 ly, and we suggest that they follow the same secretion pathway.

6 colitica exports Yop proteins via a type III secretion pathway.

7 problems is the type V (or autotransporter) secretion pathway.

8 rotein to plant cells via the hrp (type III) secretion pathway.

9 mpartment of eukaryotic cells via a type III secretion pathway.

10 oteins are normally exported via the type II secretion pathway.

11 g a possible role for these proteases in the secretion pathway.

12 the cytoplasm of macrophages via a type III secretion pathway.

13 oteins that function in the type III protein secretion pathway.

14 lated exocytosis but not in the constitutive secretion pathway.

15 require LepB and TraQ but not the SecA-SecY secretion pathway.

16 compete with each other for entrance to the secretion pathway.

17 ase B mediated via an unconventional protein secretion pathway.

18 s dictate the processing of CTDs by the T9SS secretion pathway.

19 -regulation of multiple genes in the insulin secretion pathway.

20 and EEs normally function in the surfactant secretion pathway.

21 vated macrophages through a vesicle-mediated secretion pathway.

22 pears to rely mostly on a distal step in the secretion pathway.

23 as a conduit for proteins that transit this secretion pathway.

24 s targeted to the cilia by an unconventional secretion pathway.

25 hat this chaperone determines the designated secretion pathway.

26 ia the autotransporter (or type V) bacterial secretion pathway.

27 a C(1) compound known to block the type III secretion pathway.

28 ec-dependent mechanism and not by a type III secretion pathway.

29 am-negative bacteria via the autotransporter secretion pathway.

30 Hemolysin A belongs to the two-partner secretion pathway.

31 newly identified NO-cGMP-dependent platelet secretion pathway.

32 of SDC1 and bound LPL into the sphingomyelin secretion pathway.

33 ke PNPase, regulates a terminal event in the secretion pathway.

34 d as unfolded substrates through the general secretion pathway.

35 retromer functions in the same conserved Wnt secretion pathway.

36 YopQ or YopR cleavage products to enter the secretion pathway.

37 structures assembled by the chaperone/usher secretion pathway.

38 o the periplasm of E. coli by use of the sec secretion pathway.

39 ory element with classical and non-classical secretion pathways.

40 fectors during infection, following distinct secretion pathways.

41 nk between the insulin signaling and insulin secretion pathways.

42 gy to chaperone proteins from other type III secretion pathways.

43 s in the SecB-dependent and SecB-independent secretion pathways.

44 nction signaling, synaptogenesis and insulin secretion pathways.

45 ession or increases in goblet cells or mucus secretion pathways.

46 eptide sequences and can make use of diverse secretion pathways.

47 ts in the known baseline or stimulated mucin secretion pathways.

48 in the regulated (LH) and constitutive (FSH) secretion pathways.

49 e was notable for increases in virulence and secretion pathways.

50 latelet aggregation, spreading, and granular secretion pathways.

51 apping are enriched in protein transport and secretion pathways.

52 maintenance of cell envelope and control of secretion pathways.

53 somally encoded and plasmid-encoded type III secretion pathways act independently.

54 upports the recent demonstration of separate secretion pathways adopted by the two types of particles

55 s been identified as the most common protein secretion pathway among Gram-negative bacteria.

56 occus aureus encodes the Sec-independent Ess secretion pathway, an ortholog of mycobacterial T7 secre

57 Collectively, secretion pathways ancestrally related to bacterial conj

58 ri and Legionella pneumophila - have evolved secretion pathways ancestrally related to conjugation sy

59 e data unveil a novel PKG-dependent platelet secretion pathway and a mechanism by which PKG promotes

60 ototype members of the bacterial two-partner secretion pathway and examples of the expanding number o

61 the immunoglobulin complexes in the default secretion pathway and further increased antibody product

62 the conventional endoplasmic reticulum-Golgi secretion pathway and is important for conferring host r

63 the twin-arginine translocase (Tat) protein secretion pathway and likely forms a secretion pore.

64 HMW1 adhesin is secreted via the two-partner secretion pathway and requires HMW1B for translocation a

65 nzae HMW1 adhesin occurs via the two-partner secretion pathway and requires the HMW1B outer membrane

66 lex nature of protein quality control in the secretion pathway and reveal multiple sites that recogni

67 te the effects that clathrin defects have on secretion pathways and plant growth.

68 f several exoenzymes that follow the type II secretion pathway, and decreased virulence.

69 into gastric epithelial cells via a type IV secretion pathway, and on entry into target cells, CagA

70 ing all known components of this alternative secretion pathway are clustered at the same genetic locu

71 Proteins destined to travel this secretion pathway are targeted to the secretion machine

72 d GSP nomenclature and the type II, IV and V secretion pathways are also described to show how they h

73 e ColIb conjugation system and other type IV secretion pathways are discussed.

74 of chylomicrons and chylomicron-independent secretion pathways are expected to be the next frontiers

75 These studies indicate two conserved secretion pathways are initiated by caspase-1, lysosome

76 In several instances protein secretion pathways are similar to those involved in asse

77 g of fatty acids into storage, oxidation and secretion pathways are tightly regulated.

78 gic and enteroaggregative E. coli, but their secretion pathways are unknown.

79 Genes involved in the "pancreatic secretion" pathway are the most strongly differentially

80 ron, two critical components of the type III secretion pathway, are as efficient as wild-type Salmone

81 y or the main terminal branch of the general secretion pathway, as it has also been referred to, is w

82 e by multiple mechanisms, including specific secretion pathways, autolysis, and membrane vesicle form

83 In these complex secretion pathways, bacterial chaperones direct effector

84 retion system can be modified to travel this secretion pathway by introduction of discrete mutations.

85 stacking protein (GRASP), an unconventional secretion pathway component, is required for Upd2 secret

86 s located in an operon that also encodes Hrp secretion pathway components and is part of the function

87 lla spp. by the zirTS antivirulence genes: a secretion pathway comprised of the outer membrane transp

88 Furthermore, this secretion pathway contributes to flagellar biogenesis an

89 as a substantial impact on astrocyte protein secretion pathways, contributing to motor neuron patholo

90 us intermedius mediate cell contact- and Esx secretion pathway-dependent growth inhibition of diverse

91 rters, calcium signaling, cell adhesion, and secretion pathways depleted in M-CHO while retinol metab

92 two substrates of the first Sec-independent secretion pathway described in M. tuberculosis, which we

93 rophyte) or hrp mutants defective in the Hrp secretion pathway did not induce hin1 significantly.

94 The P. gingivalis contact-dependent protein secretion pathway differs to some extent from type III p

95 U (ExoU), that is delivered via the type III secretion pathway directly into contacting host cells.

96 , and those that lacked a functional Type II secretion pathway displayed nanowires that were poorly c

97 n that is absent in FGF-2 and that the FGF-1 secretion pathway does not restrict the release of high

98 sts that B. anthracis activates the type VII secretion pathway during infection.

99 ; targets include components of the type III secretion pathway, elements involved in envelope and cel

100 kidney cancer arises from the fact that the secretion pathway enables ICG-PEG45 to be effectively ef

101 cretes the HrpZ harpin by a type III protein secretion pathway encoded by a cluster of hrp (hypersens

102 StcE is secreted by the etp type II secretion pathway encoded on pO157, and extracellular St

103 peptidoglycan hydrolases suggests that this secretion pathway evolved multiple times.

104 lus influenzae and are prototype two-partner secretion pathway exoproteins.

105 In gram-negative bacteria, the two-partner secretion pathway exports large, mostly virulence-relate

106 t that the specificity of the stress-induced secretion pathway for FGF-1 involves a carboxyl-terminal

107 MVs function as an alternate secretion pathway for Gram-negative bacteria; therefore,

108 However, the lysosomal-mediated secretion pathways for interleukin-1 beta secretion and

109 Due to differences in cellular sources and secretion pathways for TNF and IFN-gamma, the possibilit

110 that are essential components of the general secretion pathway found in a variety of Gram-negative pa

111 Autotransporter (AT) is a protein secretion pathway found in Gram-negative bacteria featur

112 ymes and toxins using the type II or general secretion pathway, found in a variety of Gram-negative b

113 Due to its secretion via multiple secretion pathways GLUC can find multiple applications a

114 -defined secretion factor B (SecB)-dependent secretion pathway, Gram-positive bacteria are a superior

115 The terminal branch of the general secretion pathway (Gsp or type II secretion system) is u

116 The general secretion pathway (GSP) of Vibrio cholerae is required f

117 The general secretion pathway (GSP), found in a wide range of bacter

118 he main terminal branch (MTB) of the general secretion pathway (GSP).

119 The two-partner secretion pathway has been identified as the most common

120 the target protein at various stages of the secretion pathway has proved to be important.

121 mical dissection of the hrp-encoded type III secretion pathway has revealed new mechanisms by which p

122 etion pathway rather than the SecA-dependent secretion pathway have not yet been identified.

123 negative pathogens, four distinct classes of secretion pathways have been identified that deliver vir

124 Understanding Arc's secretion pathway helps gain insights into its role in i

125 activity as key regulators of the HBV virion secretion pathway, highlighting its potential as a thera

126 ked, and processed via a vesicular-regulated secretion pathway; however, control of vesicular traffic

127 y and late events along the biosynthesis and secretion pathway impair trafficking.

128 Given the essentiality of the general secretion pathway in bacteria and the contribution of vi

129 15 enhanced GSIS by upregulating the insulin secretion pathway in beta-cells, which was abrogated in

130 wo different signal peptides for the protein secretion pathway in Escherichia coli.

131 The two-partner secretion pathway in Gram-negative bacteria consists of

132 etion of proteins via the type II or general secretion pathway in gram-negative bacteria requires the

133 erving as a quality control step in the apoB secretion pathway in hepatocytes.

134 The stimulus-secretion pathway in L-cells is still incompletely under

135 tered expression of genes within the insulin secretion pathway in mouse islets.

136 red into host mammalian cells via a type III secretion pathway in pathogenic Yersinia species.

137 and functional components (e.g., Sec vs. Tat secretion pathway in typical nos), and that previous nos

138 lular messengers in islets or other stimulus-secretion pathways in different cells.

139 chaperone pairs are identified from type III secretion pathways in different strains of bacteria.

140 differs to some extent from type III protein secretion pathways in enteric pathogens, as a gene homol

141 essing and the pancreatic beta cell stimulus-secretion pathway including PC1/3, PC2, GLUT-1, glucokin

142 osed whereby rejection of YopE-DHFR from the secretion pathway inhibits type III gene expression.

143 , several Yops are transported by a type III secretion pathway into the host cell cytoplasm.

144 spheroplast formation, indicating that their secretion pathway is accessible to the periplasm or to t

145 The type III secretion pathway is broadly distributed across many par

146 The Esx secretion pathway is conserved across Gram-positive bact

147 ggesting this chromosomally encoded type III secretion pathway is distinct from the flagella secretio

148 A model for the alternate chloride secretion pathway is proposed whereby chloride uptake vi

149 A specialized protein secretion pathway is used by some Gram-negative bacteria

150 system (main terminal branch of the general secretion pathway) is used by diverse gram-negative bact

151 layer in the VLDL assembly, trafficking, and secretion pathway, it also shows that NASH can occur wit

152 nderstanding of FVIII biology, including its secretion pathway, its interaction with von Willebrand f

153 cretion (TPS) is the most widely distributed secretion pathway known.

154 odium falciparum-specific IL-12p70/IFN-gamma secretion pathways known to play a key role in resistanc

155 -29c-3p targets the extracellular matrix and secretion pathways, known to be implicated in aging.

156 rain-specific differences in replication and secretion pathways linked to the vector-pathogen interac

157 rogression of tauopathy and that the exosome secretion pathway may be a therapeutic target.

158 ssically been used in studies of the general secretion pathway of Escherichia coli.

159 imilar to precursor protein D of the general secretion pathway of gram-negative bacilli, while the 20

160 The general secretion pathway of gram-negative bacteria is responsib

161 homology to proteins of the type II general secretion pathway of gram-negative bacteria.

162 ialized mode of substrate recognition by the secretion pathway of gram-positive cocci.

163 For instance, the chitinase secretion pathway of Serratia marcescens uses an endopep

164 protein production methods by employing the secretion pathway of serum-free adapted human suspension

165 ating the terminal step in the extracellular secretion pathway of TcpF.

166 acement were constructed and directed to the secretion pathway of the methylotropic yeast Pichia past

167 ich are known to be involved in the type III secretion pathway of virulence proteins.

168 retion pathway is distinct from the flagella secretion pathway of Y. enterocolitica.

169 The type II secretion pathway or the main terminal branch of the gen

170 A novel secretion pathway originally found in plants has recentl

171 on is the designation given to those protein secretion pathways, primarily in pathogenic Gram-negativ

172 We find that a Rab10-based secretion pathway promotes pericellular BM protein accum

173 the secretion of Fap1 to the SecA2-dependent secretion pathway rather than the SecA-dependent secreti

174 nsfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and eff

175 the TTSS-associated chaperones is to confer secretion-pathway specificity to their cognate secreted

176 n A, a well known inhibitor of the classical secretion pathway, suggesting that it follows an unconve

177 To test the hypothesis that the anterograde secretion pathway supplies PM components for retrograde

178 it functions at a later step in the protein secretion pathway than formation of post-Golgi secretory

179 the changes in the lipoprotein assembly and secretion pathway that are caused by 7alpha-hydroxylase.

180 that SecA2-dependent export is a new type of secretion pathway that is part of a virulence mechanism

181 Y. enterocolitica thus has three type III secretion pathways that appear to act independently.

182 Gram-negative bacteria contain multiple secretion pathways that facilitate the translocation of

183 EHEC, including those encoding the type III secretion pathway, the secreted Esp proteins, Tir, and i

184 However, the regulators and secretion pathway through which Arc capsids maneuver car

185 of bacterial pathogens utilize the type III secretion pathway to deliver effector proteins directly

186 ies use a virulence-plasmid encoded type III secretion pathway to escape the innate immune response a

187 embrane channel component used by the type I secretion pathway to export toxins and other bacterial v

188 identify novel contributions of the type III secretion pathway to post-invasion-specific processes, d

189 ggest that excess soluble A1PiZ transits the secretion pathway to the trans-Golgi network and is sele

190 variety of pathogenic bacteria use type III secretion pathways to translocate virulence proteins int

191 mber of pathogenic bacteria utilize type III secretion pathways to translocate virulence proteins int

192 een EpsE and other components of the type II secretion pathway together with these data further suppo

193 Each secretion pathway was associated with different traffick

194 The Ess (ESX secretion) pathway was previously defined as a genomic c

195 ng protein Cdc42, in the mastoparan stimulus-secretion pathway, was examined.

196 ould help identify substrates of the general secretion pathway, we analyzed the main porin of M. smeg

197 to host cells through the bacterial type III secretion pathway, where it activates disease resistance

198 nce factors are secreted via the two-partner secretion pathway, which consists of an exoprotein calle

199 of an ancestral alphaproteobacterial protein secretion pathway, which has been lost almost entirely i

200 components of the glucose-dependent insulin secretion pathway whose expression is dependent upon HNF

201 ained unchanged upon blockage of the tubular secretion pathway with probenecid, a necessary condition

202 balancing the anabolic lipoprotein assembly/secretion pathway with the cholesterol catabolic bile ac

203 ence that directly links the Mtb specialized secretion pathway with the evolutionary conserved signal

204 Thus, the Snm secretion pathway works to subvert normal macrophage res