ライフサイエンスコーパス: secretory component

1 her spot was identified as the transmembrane secretory component.

2 ved polymeric IgA and IgM with a recombinant secretory component.

3 associated with a 70-kDa glycoprotein called secretory component.

4 ctor H (FH) and secretory IgA (sIgA) via the secretory component.

5 r binding of human J chain-containing IgA to secretory component.

6 osinophil interactions with secretory IgA or secretory component.

7 ways, plus glycans present on the antibody's secretory component.

8 is showed that eosinophils bound to purified secretory component.

9 uantitative immunoblotting using Abs against secretory component.

10 SecA/SecYEG pathways, suggesting they share secretory components.

11 The structure of IgA and the associated secretory component allow IgA to survive the highly prot

12 This preferential interaction between secretory component and eosinophils may provide a novel

13 Anti-meningococcal C-specific secretory component and IgA antibody titers were closely

14 overlay assays, we found that ricin bound to secretory component and the H chain of human IgA, and th

15 henotypes are enhanced by mutations in other secretory components and are at least partially overcome

16 organized into two operons, one encoding the secretory components and the other encoding the structur

17 of desialylation included human lactoferrin, secretory component, and IgA2 that were shown to be pres

18 s in the calf intestine, while the flagellar secretory components are also necessary for the inductio

19 These vesicles appear to have a secretory component, as QPP is secreted in a functionall

20 Secretory component bound to IgA mediates transepithelia

21 production stimulated with secretory IgA or secretory component but not with serum IgA, suggesting a

22 ound that monoclonal IgA Abs with or without secretory component, but not IgG or IgM Abs, bound to th

23 bacterial OPC than did mIgA, indicating that secretory component does not hinder the effect of comple

24 bacterial IgA1 protease, demonstrating that secretory component does not prevent the proteolytic deg

25 Gentle partial deglycosylation of the SIgA secretory component enhanced susceptibility to proteolys

26 5 KO mice had normal expression of other key secretory components; however, stimulation-dependent sec

27 cific immunoglobulin A (IgA), IgA1, IgA2 and secretory component, IgG antibodies, and total IgG and I

28 S. aureus to include DMBT1(gp-340), mucin-7, secretory component, immunoglobulin A, immunoglobulin G,

29 n isotype and that the sputum IgA contains a secretory component, indicating that it is locally produ

30 nflammation, demonstrating that IgA bound to secretory component is not necessary for the development

31 f VHH-IgA with the porcine joining chain and secretory component led to the production of light-chain

32 peptides, Acan1 and Nak1, from the excretory/secretory component of parasitic hookworms for their the

33 of lung epithelia but was essential for the secretory component of phospholipid synthesis and critic

34 that bacteria from IgA-low mice degrade the secretory component of secretory IgA as well as IgA itse

35 most apparent on the heavily N-glycosylated secretory component of the antibody.

36 e joining chain (JC) and in complex with the secretory component of the pIgR.

37 ultant secretory IgA; however, the effect of secretory component on the biologic activity of IgA is u

38 cretory component was inhibited by unlabeled secretory component or secretory IgA but not by serum Ig

39 statherins, and histatins but not MG1, sIgA, secretory component, or cystatins.

40 ptional regulators (hilA and invF), type III secretory components (orgA, invG and spaR) and secreted

41 Thus, secretory component plays important roles in activating

42 igh-molecular-weight forms of IgA-containing secretory component predominated in all saliva samples.

43 Here, we report that secretory IgA and secretory component preferentially activate human eosino

44 an be competitively inhibited by recombinant secretory component protein.

45 blotting with specific antibodies to IgA and secretory component revealed that secretory IgA (SIgA) d

46 of a single-chain Fv directed against human secretory component (SC) and linked to human alpha(1)-AT

47 IgA receptor (pIgA-R) and redistribution of secretory component (SC) from bile to blood.

48 st pathogens targeting mucosal surfaces, and secretory component (SC) fulfills multiple roles in this

49 varying time intervals, and RCMV titers and secretory component (SC) levels in media or cell extract

50 from human plasma is able to associate with secretory component (SC) to generate SIgA-like molecules

51 chains produced by the plasma cells, whereas secretory component (SC), a cleavage product of the poly

52 Ig containing an unusual extra polypeptide, secretory component (SC), added during transcytosis thro

53 A2 synthesis, pIgR expression, production of secretory component (SC), IgA and relevant IgA antibodie

54 where the N-terminal domain of pIgR, termed secretory component (SC), is proteolytically cleaved and

55 IL-4 and IFN-gamma increase release of secretory component (SC), the polymeric IgA (plgA)-bindi

56 Western blot analysis with an Ab to secretory component (SC), the portion of the pIgR that r

57 the polymeric Ig-receptor ectodomain, called secretory component (SC).

58 the dIgA and the pIgR ectodomain, called the secretory component (SC).

59 roteolytic cleavage releases the ectodomain (secretory component [SC]) as an integral component of se

60 al secretions, where the cleaved ectodomain (secretory component; SC) becomes a component of secretor

61 was enhanced synergistically by immobilized secretory component; secretory component showed no effec

62 stically by immobilized secretory component; secretory component showed no effect on neutrophil activ

63 anti-HIV IgA was frequently associated with secretory component, suggesting transepithelial transpor

64 Secretory component, the cleaved epithelial receptor for

65 isting of a single-chain Fv directed against secretory component, the extracellular portion of the pI

66 Here by binding human secretory component to overlapping decapeptides of Calph

67 biological functions for trout pIgR or trout secretory component (tSC) remain unknown.

68 The binding of 125I-labeled secretory component was inhibited by unlabeled secretory

69 The distribution of axonal secretory components was evaluated in axons of the sciat

70 vel of PIGR expression in the cells and PIGR secretory component were evaluated by real-time quantita