ライフサイエンスコーパス: sedate

1 ause they are either too sick or too heavily sedated.

2 s can be activated in children who have been sedated.

3 1.02-1.10) and a noninferior time adequately sedated.

4 all cases but 2 because all the babies were sedated.

5 CT imaging of the circumpapillary RNFL while sedated.

6 randomized studies, 621 (34.4%) of whom were sedated.

7 of ERK renders a stimulatory dose of ethanol sedating.

8 uce increased activity, while high doses are sedating.

9 (-5), "deeply sedated" (-4 to -3), "lightly sedated" (-2 to 0), and "agitated" (+1 to +4).

10 of medical/surgical patients ventilated and sedated 24 hours or more.

11 chmond Agitation- Sedation Scale = -5, -4), "sedated" (-3, -2, -1), "awake" (0), "agitated" (+1, +2,

12 four levels denoted "comatose" (-5), "deeply sedated" (-4 to -3), "lightly sedated" (-2 to 0), and "a

13 at lorazepam patients were more likely to be sedated (66.9% vs 50%, respectively; absolute risk diffe

14 The exposed group were adequately sedated 74% (95% CI, 72-75%) of the study time compared

15 articipants were nonsedated (awake), lightly sedated (a slowed response to conversation), and deeply

16 ater under ultrasound guidance with patients sedated, achieving a success rate of 76%.

17 ficantly greater odds of being restrained or sedated across all categories compared with non-Hispanic

18 rmine the most effective agent with which to sedate adult patients who have respiratory failure that

19 rmine the most effective agent with which to sedate adult patients who have respiratory failure that

20 Sedated adults (>/=18 years of age) in the ICU who had b

21 Placing sedated adults in the lateral position significantly red

22 After a single, sedating alcohol exposure, flies experienced loss of nig

23 On the day of shock, the animals were sedated (alpha-chloralose) and 50 mL/kg of arterial bloo

24 reatment of alcoholism and may provide a non-sedating alternative for enhancing GABA(A) receptor func

25 routes of administration), time required to sedate and before discharge, American Society of Anesthe

26 Average time to sedate and decrease in V O2 were not different.

27 Patients on ECMO are frequently maintained sedated and immobilized until weaning from ECMO, first,

28 Six pigs were sedated and mechanically ventilated for 2.5 days with pa

29 In sedated and mechanically ventilated septic patients with

30 parameters to define fluid responsiveness in sedated and mechanically ventilated septic patients.

31 penditure in critically ill children who are sedated and mechanically ventilated; the degree of reduc

32 surgical, ventilated and nonventilated, and sedated and nonsedated adult ICU patients.

33 Comparing survival of sedated and nonsedated patients, the sedation approach w

34 few studies exist comparing the survival of sedated and nonsedated patients.

35 All were sedated and paralyzed and received positive-pressure ven

36 Infants and children who were sedated and paralyzed and were receiving mechanical vent

37 Twenty-five consecutive sedated and paralyzed patients with acute respiratory di

38 otein (EGFP) in their endothelial cells were sedated and small intraocular injections of PBS were mad

39 responses to auditory and noxious stimuli in sedated and unresponsive states.

40 In patients, compared with sedated c-EGD, sedated and unsedated sc-EGD were 96% and 97% accurate,

41 ty, tolerability, and diagnostic accuracy of sedated and unsedated sc-EGD were determined by having e

42 Sedated and unsedated sc-EGD were technically feasible a

43 Six matched subjects were similarly sedated and ventilated but were not paced.

44 cing therapy for protecting the diaphragm in sedated and ventilated pigs.

45 Patients are lightly sedated and ventilated with the lowest pressure providin

46 proteins, in mechanically ventilated, deeply sedated and/or pharmacologically paralysed intensive car

47 at adult Drosophila develop tolerance to the sedating and motor-impairing effects of ethanol with kin

48 Sedating and novel antidepressants may improve sleep con

49 lunteers at three behavioral states: awake, "sedated" and "unresponsive." Performance in a verbal tas

50 ed into a central venous catheter of intact, sedated, and mechanically ventilated rats.

51 hs) were compared with tracheally intubated, sedated, and restrained patients (group 2, n = 79; mean

52 The anxiolytic, sedating, and myorelaxant effects of BZDs are mediated b

53 The rabbits were sedated, anesthetized, and instrumented with tracheostom

54 patients, lower body weight, study location, sedated/anesthetized patients, studies performed and int

55 aortic pressures were recorded in conscious, sedated animals, and the 3D marker coordinates were comp

56 automatically in a bottom-up manner even in sedated animals, is critical to the creation of a map of

57 In decerebrated, spinalised, pentobarbitone-sedated animals, mustard oil applied to any site on the

58 imaging approaches or have been conducted in sedated animals.

59 lysis was significantly impaired in propofol-sedated animals.

60 ite widespread use of standard hypnotics and sedating antidepressants for chronic insomnia, their rol

61 Sedating antihistamines may impair driving performance a

62 was associated with similar time adequately sedated as a matched unexposed group although no reducti

63 All infants were sedated as part of the routine care policy.

64 A similar threshold was estimated for sedated autistic subjects on the basis of differences be

65 basis of differences between nonsedated and sedated autistic subjects.

66 enabled identification of 26 of the 27 (96%) sedated autistic subjects.

67 iod, animals were studied in a closed-chest, sedated, autonomically blocked state.

68 f activation and connectivity in the lightly sedated awake mouse brain and provide evidence supportin

69 A review of the data on all patients sedated between 1997 and 2003 for magnetic resonance ima

70 Non-sedated brain MRI was acquired for full-term (n = 13) an

71 s large populations of neurons in normal and sedated brains.

72 Many can be sedated, but others will need anaesthesia with careful a

73 dures under sedation or anesthesia, 41% were sedated by non-anesthesiologists.

74 sc-EGD was only slightly worse than that of sedated c-EGD (median, 2 vs. 1 on a scale of 1-10).

75 512.4 US dollars (+/- 100.8 US dollars) for sedated C-EGD and 328.6 US dollars (+/- 70.3 US dollars)

76 -EGD are as satisfied as patients undergoing sedated C-EGD and are just as willing to repeat an unsed

77 patients randomized to unsedated UT-EGD and sedated C-EGD were similar.

78 In patients, compared with sedated c-EGD, sedated and unsedated sc-EGD were 96% and

79 t EGD were randomized to unsedated UT-EGD or sedated C-EGD.

80 toxin infusions were investigated for 96 hin sedated canines receiving mechanical ventilation.

81 ional sleep promotion bundles should include sedated children and could be applicable in multicenter

82 We used DTI to investigate the brains of sedated children with autism (n = 39) and naturally asle

83 In conscious, sedated children with myocardial hypertrophy, systolic f

84 Handheld OCT imaging in sedated children with optic pathway gliomas produces hig

85 atient acceptance during unsedated or mildly sedated colonoscopy.

86 and sedation doses in unsedated and lightly sedated colonoscopy.

87 Noninferiority of time adequately sedated (COMFORT Behavior Score 11-16) while mechanicall

88 and without (phase 4) sedation, followed by sedated conventional EGD (c-EGD) (Olympus GIF-100 or GIF

89 paring unsedated ultrathin EGD (UT-EGD) with sedated conventional EGD (C-EGD) in a diverse American p

90 ally decrease the costs and complications of sedated conventional EGD.

91 a frequent phenomenon recently recognized in sedated critically ill patients under controlled ventila

92 orneal damage in mechanically ventilated and sedated critically ill patients.

93 Marker images were obtained in sedated dogs by simultaneous biplane videofluoroscopy 7

94 The PLR in healthy, mildly sedated dogs could be elicited at low light intensities

95 rms included increased use of restraints and sedating drugs and decreased efforts to mobilize patient

96 ted after rewarming while two were once more sedated due to pneumonia requiring invasive ventilator t

97 ute locomotor-activating effect, but not the sedating effect, of ethanol.

98 imulating effects of alcohol and reduced the sedating effects compared to wild-type mice, despite sim

99 nced during the rising limb-to-peak BrAC and sedating effects emerged during the declining limb.

100 A reduced sensitivity to the sedating effects of alcohol is a characteristic associat

101 We further examined acute stimulating and sedating effects of alcohol on locomotor activity, loss

102 /-)) mice display reduced sensitivity to the sedating effects of clozapine compared with wild-type (W

103 erved biochemical pathway that underlies the sedating effects of ethanol in Drosophila.

104 The RC transcript mediates the sedating effects of ethanol, while the RA transcript reg

105 ing RhoGAP18B, are strongly resistant to the sedating effects of ethanol.

106 sent in alphaCaMKII(T286A) mice, whereas the sedating effects of high-dose (3.5 g/kg) were preserved

107 effects and/or resistant to its aversive and sedating effects.

108 hotography, fundus autofluorescence imaging, sedated electroretinography, optical coherence tomograph

109 onal 8-11-mm endoscopes is an alternative to sedated endoscopy but is generally perceived as unaccept

110 n/ventilation (SJOV) can reduce hypoxemia in sedated endoscopy but may increase minor side effects li

111 d cholinergic activity synergized with a sub-sedating ethanol exposure to cause sleep deficits.

112 d, suggesting that CNS-depressant effects of sedating ethanol exposures are required for long-lasting

113 intracortical microstimulation techniques in sedated female cebus monkeys while recording EMG signals

114 ents, who were ventilated and expected to be sedated for >2 days, were studied for 50 hrs, beginning

115 scopy (p < 0.001), and patients who were not sedated for endoscopy were more likely to rate the Cytos

116 d the sedation target was "sedated" or "very sedated" for 59%, "calm and cooperative" for 25%, and "u

117 We found more patients with delirium in the sedated group (96% vs 69% of patients; p = 0.002) and in

118 4% in the nonsedation group and 37.0% in the sedated group (difference, 5.4 percentage points; 95% co

119 verall, 23.2% (n/N = 26/112) patients on non-sedating H(1) -antihistamines (nsAH) and 41.9% (n/N = 44

120 Non-sedating H(1) -antihistamines (nsAH) are the most common

121 ty to capture gastrointestinal biopsies from sedated human participants.

122 tissues, in an in vivo porcine model, and in sedated human participants.

123 are safe and proven to improve outcomes for sedated ICU patients when these approaches result in red

124 All patients were sedated immediately after the first 2.5-mg/kg propofol l

125 ods to improve outcomes for patients who are sedated in the ICU.

126 theterization laboratory, and 51 were deeply sedated in the intensive care unit after open heart surg

127 Children who required MRI were sedated in the unit by designated sedationist nurses, wh

128 ons of the gut using endoscopy in fasting or sedated individuals(7).

129 rway (Raw) and tissue (Rti) resistance in 16 sedated infants (age 15 to 88 wk) with a history of whee

130 Telemetered and sedated KO(alphaMHC-Cre) and KO(HCN4-CreERT2) mice show

131 vered using positive airflow via facemask to sedated macaques pre- and post-infection.

132 rst 7 days of an ICU stay; (4) do not deeply sedate mechanically ventilated patients without a specif

133 (six treated and four control animals) were sedated, mechanically ventilated and connected to an ext

134 Twenty-four sedated, mechanically ventilated patients immediately pr

135 cts intensive care unit-acquired weakness in sedated, mechanically ventilated patients.

136 Nonanesthetized, sedated, mechanically ventilated pigs.

137 Forty sedated, mechanically ventilated, instrumented canines c

138 Nonanesthetized, sedated, mechanically ventilated, minimally invasive swi

139 d not differ between the time awake vs. time sedated [median [interquartile range] of 0% [0, 0] compa

140 proportion of patients receiving their first sedating medication via the oral route increased after t

141 proportion of patients receiving their first sedating medication via the oral route.

142 r), the proportion of patients receiving any sedating medication was similar between time periods (11

143 to reversible risk factors, limiting use of sedating medications (especially benzodiazepines), effec

144 Among 1178 patients receiving sedating medications during implementation (860 [73.0%]

145 nd reserving use of antipsychotics and other sedating medications for treatment of severe agitation t

146 Sedating medications such as benzodiazepines should be u

147 olic derangements, hypoxemia, or exposure to sedating medications that may have contributed to the de

148 e to their underlying illness and the use of sedating medications.

149 venom increased left ventricular function in sedated mice in vivo, prolonged ventricular repolarizati

150 f the contralateral barrel cortex in lightly sedated mice, while interhemispheric inhibition reduces

151 onor cells directly into the femur cavity of sedated mice.

152 he impact of bulk motion is reduced in a non-sedated neonatal patient and (b) where the observation o

153 females and cytokine levels were blunted in sedated NHPs when compared to awake cooperating NHPs.

154 slowed response to conversation), and deeply sedated (no conversational response, rousable by loud co

155 ly higher proportion of patients was lightly sedated on days 1, 2, and 3 (12/19 [63.2%], 19/21 [90.5%

156 intensive care unit patients who are either sedated or awake, and may help preserve muscle architect

157 Older children who are not sedated or restrained and who are allowed liberal physic

158 neurons in the VLPO, but only when mice are sedated or unconscious.

159 acheal or tracheostomy tube with the patient sedated or under general anesthesia.

160 Third-line antiepileptic drug therapies with sedating or anesthetic effects predicted poor outcome an

161 ute of administration, short duration, and a sedating or energizing effect.

162 esic infusions, and the sedation target was "sedated" or "very sedated" for 59%, "calm and cooperativ

163 mulus located inside the RF in nitrous oxide sedated owls.

164 , 0] compared with 0% [0, 0] while they were sedated [p=.17]).

165 are unit within 6 hours of surgery and while sedated, paralyzed, and mechanically ventilated.

166 nocephalus) were anesthetized with ketamine, sedated, paralyzed, and mechanically ventilated.

167 Pigs were tracheally intubated, sedated, paralyzed, and mechanically ventilated.

168 n-induced fulminant hepatic failure who were sedated, paralyzed, and mechanically ventilated; 16 age-

169 o cynocephalus), anesthetized with ketamine, sedated, paralyzed, mechanically ventilated for 11 days,

170 identifying hypoventilation and apnea in the sedated patient at an earlier stage than conventional mo

171 cedures are best accomplished in the lightly sedated patient, who is breathing spontaneously, whereas

172 To sedate patients in the ICU, midazolam is commonly admini

173 f propofol but not midazolam are required to sedate patients managed with PH.

174 0.002) and increased duration of delirium in sedated patients (median 5 vs 1 d; p < 0.001).

175 tation and reducing the proportion of deeply sedated patients (primary outcome).

176 Heavily sedated patients (SAS score = 1-2, n = 20) had higher FI

177 dependent of brain function, even in heavily sedated patients during high acuity of their disease.

178 Very sedated patients had BIS scores ranging from 35 to 98, w

179 Mildly sedated patients had BIS scores ranging from 67 to 91, w

180 Sedated patients had received more sedatives, whereas do

181 and the need for capnography when monitoring sedated patients varied.

182 rvention group, and the proportion of deeply sedated patients was reduced from 60.2% to 38.8% ( p < 0

183 Sedated patients were randomly assigned (1:1) to receive

184 The finding of lower S100-beta levels in DEX-sedated patients with GCS less than 13 warrants further

185 rt, while maintaining diaphragm activity, in sedated patients with lung injury.

186 Sedated patients with severe traumatic brain injury.

187 impairments (six nonsedated patients vs four sedated patients) or severe cognitive impairments (16 no

188 ion, 3) personnel responsible for monitoring sedated patients, 4) skills and training of individuals

189 e found between the scores in nonsedated and sedated patients.

190 l stroke research as stroke rarely occurs in sedated patients.

191 on, and 5) equipment required for monitoring sedated patients.

192 ve impairments (16 nonsedated patients vs 17 sedated patients; p = 0.71).

193 tives, volatile agents are capable of deeply sedating patients, which can have respiratory depressant

194 tudy was to create a protocol for a complete sedated piglet transthoracic echocardiogram.

195 Eight sedated pigs that had been previously instrumented for c

196 by using ex vivo porcine ureter segments and sedated pigs that, with respect to the administration of

197 non-spinalised, decerebrated, pentobarbitone-sedated preparations, flexor reflexes were facilitated s

198 st that 5HT(2A)Rs may also contribute to the sedating properties of these medications in humans.

199 in is instilled directly into the tears of a sedated rabbit, and phosphorescence is measured before a

200 Studying sedated rabbits randomized equally into control animals,

201 Using a healthy, sedated rat model of NAc-DBS, we employed both evoked- a

202 In lightly sedated rats, we found that focal enhancement of motor c

203 n somatosensory cortical barrels of fentanyl-sedated rats.

204 neurovascular coupling was intact in lightly sedated, responsive mice genetically lacking astrocytic

205 ing on cortical blood flow in awake, lightly sedated, responsive mice using multiphoton laser-scannin

206 coupling in visual cortex of awake, lightly sedated, responsive mice.

207 liably discriminate (accuracy = 79%) between sedated (Richmond Agitation-Sedation Scale < 0) and nons

208 5 to 7), 26% were calm (SAS 4), and 29% were sedated (SAS 1 to 3).

209 d from unarousable (SAS score of 1), to very sedated (SAS score of 2), to mildly sedated (SAS score o

210 to very sedated (SAS score of 2), to mildly sedated (SAS score of 3).

211 d assessment of the technical feasibility of sedated sc-EGD and the tolerability of unsedated sc-EGD,

212 lane videofluoroscopy in seven closed-chest, sedated sheep before and during asynchronous LV pacing.

213 allow for successful acquisition during non-sedated sleep.

214 lishing the feasibility of functional MRI in sedated songbirds, our results demonstrate spatial codin

215 ) curves from near TLC to FRC in 49 healthy, sedated, spontaneously breathing infants of 1 to 104 wk

216 PV, left atrial (LA) and LV pressures in 10 sedated, spontaneously breathing normal dogs.

217 hypnosis as discrete elements comprising the sedated state has facilitated an individualized approach

218 ce of its increased influence, in the mildly sedated state, over a few highly central cortical region

219 th after instrumentation in the closed-chest sedated state.

220 o later with the animals in the closed-chest sedated state.

221 e in oxygen consumption (V O2) from awake to sedated state.

222 fractions of ischemic time between awake and sedated states persisted with analysis of the subgroup o

223 Spontaneously breathing, ketamine-sedated swine (4 to 8 wks of age) were given an intraven

224 The mean time to sedate the patient (+/- SD) was 23.6 minutes +/- 15.2 fo

225 ve] to +4 [combative]) was -2 to +1 (lightly sedated to restless).

226 h any of the preparatory interventions, were sedated, unconscious, hemodynamically unstable, developm

227 heal tube was assured, and all patients were sedated using continuous infusions of midazolam and/or f

228 Patients sedated using inhaled volatile agent displayed faster re

229 The animals were sedated, ventilated, and connected to the artificial lun

230 Times to sedate were assessed by consensus agreement among nurses

231 us and rhesus macaques either cooperating or sedated were compared.

232 tory pressures of < 5 cm H2O, paralyzed, and sedated) were examined (n = 12), the correlation between

233 10 mice ranging in age from P14 to P206 were sedated with 1% isoflurane.

234 Conclusions: In patients 65 years of age sedated with dexmedetomidine and propofol combination, p

235 Patients were sedated with dexmedetomidine or lorazepam for as many as

236 Patients sedated with dexmedetomidine spent more time within 1 RA

237 l percentage of objects recalled by patients sedated with either drug.

238 mechanical ventilation and three others were sedated with intravenous chlormethiazole.

239 were given the choice of having their child sedated with intravenously administered propofol or pent

240 .006) were significantly shorter in patients sedated with isoflurane when compared with IV sedation a

241 animal experiments were performed in animals sedated with ketamine or anesthetized with ketamine/diaz

242 f their sedation goal compared with patients sedated with lorazepam (median percentage of days, 80% v

243 ons to relieve obstruction than did patients sedated with pentobarbital (23% vs 0%, P < .001).

244 g or CT, infants younger than 12 months were sedated with PO pentobarbital (4-8 mg per kilogram body

245 end of the treatment period, each animal was sedated with propofol and administered a bolus of fenflu

246 years +/- 3.1), who underwent imaging while sedated with propofol as part of routine clinical MR eva

247 very after traumatic brain injury, rats were sedated with propofol either during or 2 hours after exp

248 Patients sedated with propofol underwent significantly more airwa

249 ministering propofol and monitoring patients sedated with propofol, and the need for capnography when

250 In the posttrauma protocol, animals were sedated with sevoflurane during the controlled cortical

251 neuromuscular blockade (46%) or were heavily sedated with State Behavioral Scale scores -3/-2 (34%) b

252 Eight patients were adequately sedated with the starting propofol dose regimen, whereas

253 ity of whom were mechanically ventilated and sedated, with fever > or =38.3 degrees C for >2 consecut

254 scores (3.3 vs. 1.0, p = .036) and were more sedated, with higher suppression ratios (3.5 vs. 0.6, p

255 Three sedated young children underwent thin-section computed t

256 noninvasive functional MRI method in mildly sedated zebra finches (Taeniopygia guttata) to localize